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The map label for this gene is ubiA

Identifier: 115350673

GI number: 115350673

Start: 694237

End: 695109

Strand: Direct

Name: ubiA

Synonym: Bamb_0619

Alternate gene names: 115350673

Gene position: 694237-695109 (Clockwise)

Preceding gene: 115350672

Following gene: 115350680

Centisome position: 19.52

GC content: 65.98

Gene sequence:

>873_bases
ATGCTTGCCCGCTTTCCCCTGTATCTGCGGCTCGTCCGGATGGACAAGCCGATCGGCAGCCTGCTGCTGCTGTGGCCGAC
GCTCAACGCACTGTGGATCGCGTCGGACGGCCATCCGCGCTGGCCGCTGCTCGCGATCTTCGTGCTCGGCACGCTGCTGA
TGCGCTCGGCCGGCTGCGCGATGAACGACTATGCCGACCGCGATTTCGACCGTCACGTGAAGCGCACGGCCGACCGGCCG
CTGACGTCCGGCAAGATCCGCGCATGGGAAGCCGTCGCGATCGCGGTGGTGCTGGCCTTCATCTCGTTCCTGCTGATCCA
GCCGCTCAATACGCTGACGAAAGAGCTGTCGGTCGTCGCGCTGTTCGTCGCGGGCTCGTATCCGTTCATGAAGCGTTTCT
TCGCGATTCCGCAGGCGTATCTCGGCATCGCGTTCGGCTTCGGCATCCCGATGGCGTTCGCGGCCGTGCAGGACACGGTG
CCGATGCTCGCGTGGGTGATGCTGATCGCGAACATCTTCTGGTCGGTCGCGTACGACACCGAATACGCGATGGTCGACCG
CGACGACGACATCAAGATCGGCATTCGCACGTCCGCGCTGACGTTCGGCCGCTTCGACGTCGCGGCCGTCATGCTCTGCT
ATGCGGCGACGCTCGGCATCTATGTGTGGATCGGCGTGACGCTCGGCTTCGGCCTCGCATATTGGGCCGGCTGGGCCGCG
GCGGTCGGCTGCGCGCTGTATCACTACACGCTGATCAAGGACCGCGAGCGGATGCCGTGCTTCGCGGCGTTCCGGCACAA
CAACTGGCTCGGCGGCGTGCTGTTCGCGGGGATCGCCGCGCACTACCTGCTGGCGGGCACGGCAGGCAACTGA

Upstream 100 bases:

>100_bases
GCCGGCGCGCGGGTCGCGGCAGCCGTCGCGGGCCTGCCCGACATGACGTGACCCGCCGCTCGGCTCTAAAATGCCGGGGT
TATCTTCCCGGTGCTTCGCC

Downstream 100 bases:

>100_bases
AGAGGCCGCGCCCGGCCGCGATGCCAACTAAAAAGCGGCCGAGGCCGCTTTTTTGTTGCCGGTGCCGGAAGCCCGGCGGA
GCGTGCCGCGCTTACGCGCG

Product: 4-hydroxybenzoate octaprenyltransferase

Products: @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGHPRWPLLAIFVLGTLLMRSAGCAMNDYADRDFDRHVKRTADRP
LTSGKIRAWEAVAIAVVLAFISFLLIQPLNTLTKELSVVALFVAGSYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTV
PMLAWVMLIANIFWSVAYDTEYAMVDRDDDIKIGIRTSALTFGRFDVAAVMLCYAATLGIYVWIGVTLGFGLAYWAGWAA
AVGCALYHYTLIKDRERMPCFAAFRHNNWLGGVLFAGIAAHYLLAGTAGN

Sequences:

>Translated_290_residues
MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGHPRWPLLAIFVLGTLLMRSAGCAMNDYADRDFDRHVKRTADRP
LTSGKIRAWEAVAIAVVLAFISFLLIQPLNTLTKELSVVALFVAGSYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTV
PMLAWVMLIANIFWSVAYDTEYAMVDRDDDIKIGIRTSALTFGRFDVAAVMLCYAATLGIYVWIGVTLGFGLAYWAGWAA
AVGCALYHYTLIKDRERMPCFAAFRHNNWLGGVLFAGIAAHYLLAGTAGN
>Mature_290_residues
MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGHPRWPLLAIFVLGTLLMRSAGCAMNDYADRDFDRHVKRTADRP
LTSGKIRAWEAVAIAVVLAFISFLLIQPLNTLTKELSVVALFVAGSYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTV
PMLAWVMLIANIFWSVAYDTEYAMVDRDDDIKIGIRTSALTFGRFDVAAVMLCYAATLGIYVWIGVTLGFGLAYWAGWAA
AVGCALYHYTLIKDRERMPCFAAFRHNNWLGGVLFAGIAAHYLLAGTAGN

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=275, Percent_Identity=33.8181818181818, Blast_Score=147, Evalue=9e-36,
Organism=Escherichia coli, GI1790473, Length=275, Percent_Identity=55.2727272727273, Blast_Score=282, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI17553718, Length=280, Percent_Identity=32.1428571428571, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI32565247, Length=280, Percent_Identity=31.4285714285714, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17553720, Length=337, Percent_Identity=27.893175074184, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI32565245, Length=137, Percent_Identity=37.956204379562, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI32565243, Length=133, Percent_Identity=37.593984962406, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324370, Length=290, Percent_Identity=28.2758620689655, Blast_Score=108, Evalue=7e-25,
Organism=Drosophila melanogaster, GI21355567, Length=296, Percent_Identity=34.4594594594595, Blast_Score=140, Evalue=9e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 32150; Mature: 32150

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGHPRWPLLAIFVLGTLLMRSAGCA
CCCCHHHHHHHHHHCCCHHHHEEHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCC
MNDYADRDFDRHVKRTADRPLTSGKIRAWEAVAIAVVLAFISFLLIQPLNTLTKELSVVA
CCHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVAGSYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTVPMLAWVMLIANIFWSVAYDT
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EYAMVDRDDDIKIGIRTSALTFGRFDVAAVMLCYAATLGIYVWIGVTLGFGLAYWAGWAA
EEEEECCCCCEEEEEEECEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGCALYHYTLIKDRERMPCFAAFRHNNWLGGVLFAGIAAHYLLAGTAGN
HHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGHPRWPLLAIFVLGTLLMRSAGCA
CCCCHHHHHHHHHHCCCHHHHEEHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCC
MNDYADRDFDRHVKRTADRPLTSGKIRAWEAVAIAVVLAFISFLLIQPLNTLTKELSVVA
CCHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVAGSYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTVPMLAWVMLIANIFWSVAYDT
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EYAMVDRDDDIKIGIRTSALTFGRFDVAAVMLCYAATLGIYVWIGVTLGFGLAYWAGWAA
EEEEECCCCCEEEEEEECEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGCALYHYTLIKDRERMPCFAAFRHNNWLGGVLFAGIAAHYLLAGTAGN
HHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-Hydroxybenzoate; Farnesylfarnesylgeraniol [C]

Specific reaction: 4-Hydroxybenzoate + Farnesylfarnesylgeraniol = @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA