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The map label for this gene is yiaJ [H]

Identifier: 115350572

GI number: 115350572

Start: 583323

End: 584222

Strand: Direct

Name: yiaJ [H]

Synonym: Bamb_0518

Alternate gene names: 115350572

Gene position: 583323-584222 (Clockwise)

Preceding gene: 115350571

Following gene: 115350573

Centisome position: 16.4

GC content: 69.56

Gene sequence:

>900_bases
ATGACCAAGATGCCCGAATCCCTTGCCCTCGACGCCCGGCGTGCGACGCCGGACGATGCGCCGCTGACCGACAGCATCGG
CGCGACCAGCACGCCGCTCGACCTCGCCGCGCAGCAGGCCGGCACGCAGACGCTGTTGCGCGGCCTCGCGATCCTCGAAG
CGATCGCGAACGGCGCGCGCGACATGCGTGCGATCGGCGCCGCGCTCGGCACGACGCGCAGCACGACGCACCGTCTCGTC
AGCAGCCTCGTGCAGGCGCGCTACCTGCGACAGGTGCAGGGCGGTTACCTGCTCGGCCCGAAGCTGATCGAGCTCGGCAC
GATCGCGCTCGAGCAGATGCCGCTCACGGCGGTCGCGCGGCCCCACCTCGAAGCGCTCGCGGAAGCGACGCTCGACACGA
TTCACCTCGGCGTGCGCGACGGCGACGACGTGCTGTACATCGACAAGATTCCCGGCACGCGTGGCCTCGAGATGCGTTCG
CGCGTCGGCCACCGGATGCCGCTCGCCTCCACCGGCATCGGCAAGGCGATGATGCTCGACCTCGATCCGGACGTGTGGCG
CTCGCTGTTCGAAGCCGCGCGCCGCGCACTGGCCGGCGTCAATTTCAAGCCGGACAACCGCCCCGAGACGAGCGCGTTCC
TGCAGCGCATGGCGCACTACGCGGCCGGCGGCTACACGTTCGACCTCGAGGAAAACGAGGCGTCGATCCGCTGCGTGGCC
GCGCCGATTCGCGACGCATCGGGCGCGGTCGTCGCGGCCGTGTCGGTCGCGAGCACGATTCCGTACATGCCGCACGACCG
GATGGATGAACTGATTCCGCTCGTGCAGCGTGAAGCGCGAGCCATTTCCGCTGAACTGGGCTGGAGCCCGCCGCAAGGTA
CCCGCAGGATCAAACGATGA

Upstream 100 bases:

>100_bases
CGCTTTCCTCGGTGCATCGACCGCCGCGTTGCCGCGACGCCCGACCTCGTTCCGGCTTCGCGACCGCCGCTTCACCGATT
CCGCTGAAGAAGCCCGTTCC

Downstream 100 bases:

>100_bases
CCCATTCGACCCGGACCGCTCCGGACGCCAACTCCGCCGCCCCGTCGCTGATTGCGCTCGACTGGGGCACGACGTCGCTG
CGCGCGTATCTGTTCGATGC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: YiaKLMNOPQRS operon repressor; YiaK-S operon repressor [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTKMPESLALDARRATPDDAPLTDSIGATSTPLDLAAQQAGTQTLLRGLAILEAIANGARDMRAIGAALGTTRSTTHRLV
SSLVQARYLRQVQGGYLLGPKLIELGTIALEQMPLTAVARPHLEALAEATLDTIHLGVRDGDDVLYIDKIPGTRGLEMRS
RVGHRMPLASTGIGKAMMLDLDPDVWRSLFEAARRALAGVNFKPDNRPETSAFLQRMAHYAAGGYTFDLEENEASIRCVA
APIRDASGAVVAAVSVASTIPYMPHDRMDELIPLVQREARAISAELGWSPPQGTRRIKR

Sequences:

>Translated_299_residues
MTKMPESLALDARRATPDDAPLTDSIGATSTPLDLAAQQAGTQTLLRGLAILEAIANGARDMRAIGAALGTTRSTTHRLV
SSLVQARYLRQVQGGYLLGPKLIELGTIALEQMPLTAVARPHLEALAEATLDTIHLGVRDGDDVLYIDKIPGTRGLEMRS
RVGHRMPLASTGIGKAMMLDLDPDVWRSLFEAARRALAGVNFKPDNRPETSAFLQRMAHYAAGGYTFDLEENEASIRCVA
APIRDASGAVVAAVSVASTIPYMPHDRMDELIPLVQREARAISAELGWSPPQGTRRIKR
>Mature_298_residues
TKMPESLALDARRATPDDAPLTDSIGATSTPLDLAAQQAGTQTLLRGLAILEAIANGARDMRAIGAALGTTRSTTHRLVS
SLVQARYLRQVQGGYLLGPKLIELGTIALEQMPLTAVARPHLEALAEATLDTIHLGVRDGDDVLYIDKIPGTRGLEMRSR
VGHRMPLASTGIGKAMMLDLDPDVWRSLFEAARRALAGVNFKPDNRPETSAFLQRMAHYAAGGYTFDLEENEASIRCVAA
PIRDASGAVVAAVSVASTIPYMPHDRMDELIPLVQREARAISAELGWSPPQGTRRIKR

Specific function: Negatively controls the transcription of the yiaKLMNOPQRS operon, which may be involved in the utilization of 2,3-diketo-L-gulonate [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1789999, Length=258, Percent_Identity=32.5581395348837, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1788131, Length=266, Percent_Identity=32.3308270676692, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786468, Length=250, Percent_Identity=30, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87082359, Length=252, Percent_Identity=29.3650793650794, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788581, Length=249, Percent_Identity=31.3253012048193, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1786715, Length=253, Percent_Identity=28.4584980237154, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1790752, Length=256, Percent_Identity=23.828125, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 32222; Mature: 32091

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKMPESLALDARRATPDDAPLTDSIGATSTPLDLAAQQAGTQTLLRGLAILEAIANGAR
CCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHH
DMRAIGAALGTTRSTTHRLVSSLVQARYLRQVQGGYLLGPKLIELGTIALEQMPLTAVAR
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHCCHHHHHH
PHLEALAEATLDTIHLGVRDGDDVLYIDKIPGTRGLEMRSRVGHRMPLASTGIGKAMMLD
HHHHHHHHHHHHHHEEECCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEE
LDPDVWRSLFEAARRALAGVNFKPDNRPETSAFLQRMAHYAAGGYTFDLEENEASIRCVA
CCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEE
APIRDASGAVVAAVSVASTIPYMPHDRMDELIPLVQREARAISAELGWSPPQGTRRIKR
ECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCC
>Mature Secondary Structure 
TKMPESLALDARRATPDDAPLTDSIGATSTPLDLAAQQAGTQTLLRGLAILEAIANGAR
CCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHH
DMRAIGAALGTTRSTTHRLVSSLVQARYLRQVQGGYLLGPKLIELGTIALEQMPLTAVAR
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHCCHHHHHH
PHLEALAEATLDTIHLGVRDGDDVLYIDKIPGTRGLEMRSRVGHRMPLASTGIGKAMMLD
HHHHHHHHHHHHHHEEECCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEE
LDPDVWRSLFEAARRALAGVNFKPDNRPETSAFLQRMAHYAAGGYTFDLEENEASIRCVA
CCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEE
APIRDASGAVVAAVSVASTIPYMPHDRMDELIPLVQREARAISAELGWSPPQGTRRIKR
ECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]