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The map label for this gene is aroE

Identifier: 115350568

GI number: 115350568

Start: 578841

End: 579707

Strand: Direct

Name: aroE

Synonym: Bamb_0514

Alternate gene names: 115350568

Gene position: 578841-579707 (Clockwise)

Preceding gene: 115350567

Following gene: 115350569

Centisome position: 16.28

GC content: 72.32

Gene sequence:

>867_bases
ATGACCGCGATCGCGCCGACGAGCGGCGTCGACCGCTACGTGGTGTTCGGCAATCCGGTGGCGCACAGCAAGTCGCCGTT
CATCCACGCGCAGTTCGCCGCGCAGACGGGCGAGGCGATCACTTACGAGCACCGGCTCGCGCCGGTGGACGGCTTCGAGG
CCGCCGTGCGCGCGTTCGTCGCCGAAGGCGGGCGCGGCGCGAACGTCACCGTGCCGTTCAAGCTCGACGCGCATGCGCTC
GCCGACACGCTGTCGCCGCGCGCGGCGGCGGCCGGCGCGGTAAACACGCTGCGTTTCGACGCCGACGGCCGCATTTACGG
CGACAACACCGACGGTGTCGGCCTCGTGCGCGACATCGAATCGAATCTCGGCGTGTCGCTCGCAGGCGCGCGCATCCTGC
TGCTCGGCGCGGGCGGCGCCGCCCGCGGCGTCGTGCTGCCGATGCTCGAGCGCGCACCGCTGTCGATCACGATCGTGAAC
CGCACCGCGAGCAAGGCCGAGACGCTCGTCGGTCAGTTCACGCAGGCCGCGCACGATGCGGGCTGCGTGCTGGCGGGCGG
CGGCCCGGACACCGTACGTGCCGAACCGTACGACGTGATCGTCAACGCGACGGCCGGCAGTCTCGATGCGGCGCTGCCGG
AGTGCGACGCTGCCGCGTTCGGTGCCGGCACGCTGGCCTACGACATGATGTATGGCGCGCAGCCGACCGTGTTCATGCAG
CATGCGGCGTCGCTCGGCGCACGCACGGCCGACGGTCTCGGCATGCTGGTCGAGCAGGCGGCCGAATCGTTCTTCATCTG
GCGCGGCGTGCGGCCGGACGGCGCACCCGTGCTGGCCGCGCTGCGCCAGGCGCTCGCGGCGGCCTGA

Upstream 100 bases:

>100_bases
AAACCGAGGCCGAAGCGCTGGCCGAATCGGACGGCGCGGCGGCCGAAGGCGGCGATGCCGCGACCGGCAACGGCCAGGCA
AGCGAAGAGGGCCGCGCATC

Downstream 100 bases:

>100_bases
GCGGAGCGCGGCAGGTGGCGGCGGTAAGCGGCATGCGGCGCACGCGCACGGTCAGCCCGACCCGCTGGATCGTCTATGCG
GGTTCGGTGTTCGCGGGCGC

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MTAIAPTSGVDRYVVFGNPVAHSKSPFIHAQFAAQTGEAITYEHRLAPVDGFEAAVRAFVAEGGRGANVTVPFKLDAHAL
ADTLSPRAAAAGAVNTLRFDADGRIYGDNTDGVGLVRDIESNLGVSLAGARILLLGAGGAARGVVLPMLERAPLSITIVN
RTASKAETLVGQFTQAAHDAGCVLAGGGPDTVRAEPYDVIVNATAGSLDAALPECDAAAFGAGTLAYDMMYGAQPTVFMQ
HAASLGARTADGLGMLVEQAAESFFIWRGVRPDGAPVLAALRQALAAA

Sequences:

>Translated_288_residues
MTAIAPTSGVDRYVVFGNPVAHSKSPFIHAQFAAQTGEAITYEHRLAPVDGFEAAVRAFVAEGGRGANVTVPFKLDAHAL
ADTLSPRAAAAGAVNTLRFDADGRIYGDNTDGVGLVRDIESNLGVSLAGARILLLGAGGAARGVVLPMLERAPLSITIVN
RTASKAETLVGQFTQAAHDAGCVLAGGGPDTVRAEPYDVIVNATAGSLDAALPECDAAAFGAGTLAYDMMYGAQPTVFMQ
HAASLGARTADGLGMLVEQAAESFFIWRGVRPDGAPVLAALRQALAAA
>Mature_287_residues
TAIAPTSGVDRYVVFGNPVAHSKSPFIHAQFAAQTGEAITYEHRLAPVDGFEAAVRAFVAEGGRGANVTVPFKLDAHALA
DTLSPRAAAAGAVNTLRFDADGRIYGDNTDGVGLVRDIESNLGVSLAGARILLLGAGGAARGVVLPMLERAPLSITIVNR
TASKAETLVGQFTQAAHDAGCVLAGGGPDTVRAEPYDVIVNATAGSLDAALPECDAAAFGAGTLAYDMMYGAQPTVFMQH
AASLGARTADGLGMLVEQAAESFFIWRGVRPDGAPVLAALRQALAAA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=279, Percent_Identity=46.9534050179211, Blast_Score=236, Evalue=1e-63,
Organism=Escherichia coli, GI1787983, Length=266, Percent_Identity=29.6992481203008, Blast_Score=99, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6320332, Length=166, Percent_Identity=34.9397590361446, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29430; Mature: 29298

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAIAPTSGVDRYVVFGNPVAHSKSPFIHAQFAAQTGEAITYEHRLAPVDGFEAAVRAFV
CCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHH
AEGGRGANVTVPFKLDAHALADTLSPRAAAAGAVNTLRFDADGRIYGDNTDGVGLVRDIE
HCCCCCCEEEEEEEECHHHHHHHCCCHHHHCCCCEEEEECCCCEEECCCCCCCEEEEEHH
SNLGVSLAGARILLLGAGGAARGVVLPMLERAPLSITIVNRTASKAETLVGQFTQAAHDA
HCCCEEEECCEEEEEECCCCCCCHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHCCC
GCVLAGGGPDTVRAEPYDVIVNATAGSLDAALPECDAAAFGAGTLAYDMMYGAQPTVFMQ
CEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCHHHHH
HAASLGARTADGLGMLVEQAAESFFIWRGVRPDGAPVLAALRQALAAA
HHHHHCCCCCCHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TAIAPTSGVDRYVVFGNPVAHSKSPFIHAQFAAQTGEAITYEHRLAPVDGFEAAVRAFV
CCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHH
AEGGRGANVTVPFKLDAHALADTLSPRAAAAGAVNTLRFDADGRIYGDNTDGVGLVRDIE
HCCCCCCEEEEEEEECHHHHHHHCCCHHHHCCCCEEEEECCCCEEECCCCCCCEEEEEHH
SNLGVSLAGARILLLGAGGAARGVVLPMLERAPLSITIVNRTASKAETLVGQFTQAAHDA
HCCCEEEECCEEEEEECCCCCCCHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHCCC
GCVLAGGGPDTVRAEPYDVIVNATAGSLDAALPECDAAAFGAGTLAYDMMYGAQPTVFMQ
CEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCHHHHH
HAASLGARTADGLGMLVEQAAESFFIWRGVRPDGAPVLAALRQALAAA
HHHHHCCCCCCHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA