Click here to switch to the map view.

The map label for this gene is pepQ [H]

Identifier: 115350472

GI number: 115350472

Start: 467415

End: 469229

Strand: Direct

Name: pepQ [H]

Synonym: Bamb_0418

Alternate gene names: 115350472

Gene position: 467415-469229 (Clockwise)

Preceding gene: 115350471

Following gene: 115350473

Centisome position: 13.14

GC content: 70.74

Gene sequence:

>1815_bases
ATGAATGCCCGTCTCCCCGAAGTCTCGCCGGTGCCGGCCCGCCTCGCGCTGCTGCGCGGCGCGATGGTCCGCGAGGATCT
GGCCGCCTATCTCGTGCCGTCCGCCGATCCGCACCTGTCCGAGTACCTGCCCGAGCGCTGGCAGGCGCGCCGCTGGCTGT
CCGGTTTCACGGGCTCGGTCGGCACGCTGGTCGTGACCGCCGATTTCGCGGGCTTGTGGGTCGACAGCCGTTACTGGGTG
CAGGCCGAGGCCGAACTCGCCGGCACGGGCGTCCAGCTGATGAAGATGACGGGCGGCCAGCAGAGCGCACCCCACGTCGA
CTGGCTCGCGCAGAACGTGCCGGCCGGTGCGACGGTCGGCGTCGACGGCGCCGTGCTCGGCGTCACGGCGGCACGCGCGC
TGACGGCCGCGCTGAGCGCGCGCGGCATCGCGCTGCGCACCGACCTCGACCTGCTCGACGCGATCTGGCCGGAGCGCCCG
GGGCTGCCGGGTGACGCGGTGTTCGAGCATCTCGCGCCGCAGGCCGACACGACGCGCGCGAGCAAGCTCGCCGAAGTGCG
CCGCGCGATGCACGCGCAGGGCGCGCAATGGCATTTCGTGTCGACGCTCGACGATCTCGCGTGGCTGTTCAACCTGCGCG
GCGCCGACGTCAACTTCAACCCCGTGTTCGTCGCGCACGCGCTGATCGGTGCCGATCGCGCGACGCTGTTCGTCGCCGAC
GGCAAGGTGTCGCCGGCGCTGGCCGCGTCGCTCGCGCGGGACGGTGTCGAGGTCCGCGCATACGATGCAGTGCACGCGTC
GCTCGCGGCGCTGCCCGACGGCGCGACGCTGCTGATCGATCCGCGCCGTGTGACGTTCGGCACGCTCGAGGCCGTGCCGG
CCGGCGTGAAGCTGATCGAGGCGGTGAACCCGTCGACGTTCGCGAAGTCGCGCAAGACATCCGCCGAGATCGAGCACGTG
CGCGTGACGATGGAGCACGACGGCGCCGCGCTTGCCGAATTCTTCGCGTGGTTCGAGCAGGCGGTGAACCGCGAGACCGT
CACCGAGCTGACGATCGACGAGAAGCTAACGGCCGCGCGCGCACGGCGCCCCGGCTACGTGTCGCCGAGCTTCGCCACGA
TCGCCGGCTTCAACGCGAACGGCGCGATGCCGCACTATCGTGCAACGCCCGAGTCGCACGCGACGATCGCCGGTGACGGC
CTGCTGCTCGTCGATTCGGGCGGCCAGTACACGACCGGCACCACCGACATCACGCGCGTCGTGCCGGTCGGCACGCTCAG
CGACCTGCAGCGACGCGATTTCACGATCGTGCTGAGGTCGATGATGGCGCTGTCGCGCGCACGCTTTCCGCGCGGCATCC
GCTCGCCGATGCTCGATGCGATCGCGCGCGCGCCGATGTGGGCGGCCGGGCTCGACTACGGCCACGGCACCGGCCACGGC
GTCGGCTACTTCCTGAACGTGCACGAGGGCCCGCAGGTCATCTCGCACTACGCGCCGGCTGAGCCGCACACGGCGATGGA
AGAAGGGATGATCACGTCGATCGAGCCGGGCGTGTATCGGCCCGGCAAATGGGGCATCCGGATCGAGAACCTGGTCGTGA
ACCGCGCGGGCGGGCAGACCGAGTTCGGCGACTTCCTCGCGTTCGAGACGCTCACGTTGTGCCCGATCGACACGCGCTGC
GTGCTCGTCGAGATGCTGCATGAAGAAGAGCGCGCGTGGCTGAACGCGTATCACGCGACCGTCCGCGAGCGTGTCGGCCG
GCACGTGAGCGGCGACGCGAAGGCGTGGCTCGACGCGCGCACGCAGCCGATCTGA

Upstream 100 bases:

>100_bases
GCGAAACGCTCGAATGGCCGGTCTGCACCGGCGTCGCGTTCCTCGCCGTAGCCGTGACGGTCGCCCTGTCGGCACGTCGC
GAAAGCGCTCAGGTGAAATC

Downstream 100 bases:

>100_bases
CGCAATACGCGATACCGGCCGCACGACGGCCGGACCTTGACCGAGAGGGCAACCGATGGCAGACACCGCAGTGATCGTGA
TCGACATGCAGCGCGGGCTG

Product: peptidase M24

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MNARLPEVSPVPARLALLRGAMVREDLAAYLVPSADPHLSEYLPERWQARRWLSGFTGSVGTLVVTADFAGLWVDSRYWV
QAEAELAGTGVQLMKMTGGQQSAPHVDWLAQNVPAGATVGVDGAVLGVTAARALTAALSARGIALRTDLDLLDAIWPERP
GLPGDAVFEHLAPQADTTRASKLAEVRRAMHAQGAQWHFVSTLDDLAWLFNLRGADVNFNPVFVAHALIGADRATLFVAD
GKVSPALAASLARDGVEVRAYDAVHASLAALPDGATLLIDPRRVTFGTLEAVPAGVKLIEAVNPSTFAKSRKTSAEIEHV
RVTMEHDGAALAEFFAWFEQAVNRETVTELTIDEKLTAARARRPGYVSPSFATIAGFNANGAMPHYRATPESHATIAGDG
LLLVDSGGQYTTGTTDITRVVPVGTLSDLQRRDFTIVLRSMMALSRARFPRGIRSPMLDAIARAPMWAAGLDYGHGTGHG
VGYFLNVHEGPQVISHYAPAEPHTAMEEGMITSIEPGVYRPGKWGIRIENLVVNRAGGQTEFGDFLAFETLTLCPIDTRC
VLVEMLHEEERAWLNAYHATVRERVGRHVSGDAKAWLDARTQPI

Sequences:

>Translated_604_residues
MNARLPEVSPVPARLALLRGAMVREDLAAYLVPSADPHLSEYLPERWQARRWLSGFTGSVGTLVVTADFAGLWVDSRYWV
QAEAELAGTGVQLMKMTGGQQSAPHVDWLAQNVPAGATVGVDGAVLGVTAARALTAALSARGIALRTDLDLLDAIWPERP
GLPGDAVFEHLAPQADTTRASKLAEVRRAMHAQGAQWHFVSTLDDLAWLFNLRGADVNFNPVFVAHALIGADRATLFVAD
GKVSPALAASLARDGVEVRAYDAVHASLAALPDGATLLIDPRRVTFGTLEAVPAGVKLIEAVNPSTFAKSRKTSAEIEHV
RVTMEHDGAALAEFFAWFEQAVNRETVTELTIDEKLTAARARRPGYVSPSFATIAGFNANGAMPHYRATPESHATIAGDG
LLLVDSGGQYTTGTTDITRVVPVGTLSDLQRRDFTIVLRSMMALSRARFPRGIRSPMLDAIARAPMWAAGLDYGHGTGHG
VGYFLNVHEGPQVISHYAPAEPHTAMEEGMITSIEPGVYRPGKWGIRIENLVVNRAGGQTEFGDFLAFETLTLCPIDTRC
VLVEMLHEEERAWLNAYHATVRERVGRHVSGDAKAWLDARTQPI
>Mature_604_residues
MNARLPEVSPVPARLALLRGAMVREDLAAYLVPSADPHLSEYLPERWQARRWLSGFTGSVGTLVVTADFAGLWVDSRYWV
QAEAELAGTGVQLMKMTGGQQSAPHVDWLAQNVPAGATVGVDGAVLGVTAARALTAALSARGIALRTDLDLLDAIWPERP
GLPGDAVFEHLAPQADTTRASKLAEVRRAMHAQGAQWHFVSTLDDLAWLFNLRGADVNFNPVFVAHALIGADRATLFVAD
GKVSPALAASLARDGVEVRAYDAVHASLAALPDGATLLIDPRRVTFGTLEAVPAGVKLIEAVNPSTFAKSRKTSAEIEHV
RVTMEHDGAALAEFFAWFEQAVNRETVTELTIDEKLTAARARRPGYVSPSFATIAGFNANGAMPHYRATPESHATIAGDG
LLLVDSGGQYTTGTTDITRVVPVGTLSDLQRRDFTIVLRSMMALSRARFPRGIRSPMLDAIARAPMWAAGLDYGHGTGHG
VGYFLNVHEGPQVISHYAPAEPHTAMEEGMITSIEPGVYRPGKWGIRIENLVVNRAGGQTEFGDFLAFETLTLCPIDTRC
VLVEMLHEEERAWLNAYHATVRERVGRHVSGDAKAWLDARTQPI

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Homo sapiens, GI264681563, Length=610, Percent_Identity=37.0491803278689, Blast_Score=381, Evalue=1e-106,
Organism=Homo sapiens, GI264681565, Length=610, Percent_Identity=35.4098360655738, Blast_Score=346, Evalue=3e-95,
Organism=Homo sapiens, GI93141226, Length=604, Percent_Identity=34.2715231788079, Blast_Score=343, Evalue=2e-94,
Organism=Escherichia coli, GI1788728, Length=179, Percent_Identity=34.6368715083799, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17509539, Length=595, Percent_Identity=33.6134453781513, Blast_Score=308, Evalue=6e-84,
Organism=Caenorhabditis elegans, GI25149105, Length=614, Percent_Identity=27.1986970684039, Blast_Score=235, Evalue=5e-62,
Organism=Saccharomyces cerevisiae, GI6322999, Length=655, Percent_Identity=30.6870229007634, Blast_Score=289, Evalue=7e-79,
Organism=Drosophila melanogaster, GI17137632, Length=613, Percent_Identity=34.257748776509, Blast_Score=315, Evalue=5e-86,
Organism=Drosophila melanogaster, GI161078230, Length=606, Percent_Identity=27.5577557755776, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI21357287, Length=606, Percent_Identity=27.5577557755776, Blast_Score=240, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 65201; Mature: 65201

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARLPEVSPVPARLALLRGAMVREDLAAYLVPSADPHLSEYLPERWQARRWLSGFTGSV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
GTLVVTADFAGLWVDSRYWVQAEAELAGTGVQLMKMTGGQQSAPHVDWLAQNVPAGATVG
EEEEEEECCCEEEECCEEEEEEECHHCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCEEC
VDGAVLGVTAARALTAALSARGIALRTDLDLLDAIWPERPGLPGDAVFEHLAPQADTTRA
CCCHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHH
SKLAEVRRAMHAQGAQWHFVSTLDDLAWLFNLRGADVNFNPVFVAHALIGADRATLFVAD
HHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEEC
GKVSPALAASLARDGVEVRAYDAVHASLAALPDGATLLIDPRRVTFGTLEAVPAGVKLIE
CCCCHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCEEEECCCEEEEHHHHHCCCCHHHHH
AVNPSTFAKSRKTSAEIEHVRVTMEHDGAALAEFFAWFEQAVNRETVTELTIDEKLTAAR
HCCCHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHCHHHHHEEEHHHHHHHHH
ARRPGYVSPSFATIAGFNANGAMPHYRATPESHATIAGDGLLLVDSGGQYTTGTTDITRV
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCEECCCCCCEEE
VPVGTLSDLQRRDFTIVLRSMMALSRARFPRGIRSPMLDAIARAPMWAAGLDYGHGTGHG
EECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
VGYFLNVHEGPQVISHYAPAEPHTAMEEGMITSIEPGVYRPGKWGIRIENLVVNRAGGQT
EEEEEEECCCHHHHHHCCCCCCCHHHHCCCEEECCCCCCCCCCCCEEEEEEEEECCCCCC
EFGDFLAFETLTLCPIDTRCVLVEMLHEEERAWLNAYHATVRERVGRHVSGDAKAWLDAR
CHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCC
TQPI
CCCC
>Mature Secondary Structure
MNARLPEVSPVPARLALLRGAMVREDLAAYLVPSADPHLSEYLPERWQARRWLSGFTGSV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
GTLVVTADFAGLWVDSRYWVQAEAELAGTGVQLMKMTGGQQSAPHVDWLAQNVPAGATVG
EEEEEEECCCEEEECCEEEEEEECHHCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCEEC
VDGAVLGVTAARALTAALSARGIALRTDLDLLDAIWPERPGLPGDAVFEHLAPQADTTRA
CCCHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHH
SKLAEVRRAMHAQGAQWHFVSTLDDLAWLFNLRGADVNFNPVFVAHALIGADRATLFVAD
HHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEEC
GKVSPALAASLARDGVEVRAYDAVHASLAALPDGATLLIDPRRVTFGTLEAVPAGVKLIE
CCCCHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCEEEECCCEEEEHHHHHCCCCHHHHH
AVNPSTFAKSRKTSAEIEHVRVTMEHDGAALAEFFAWFEQAVNRETVTELTIDEKLTAAR
HCCCHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHCHHHHHEEEHHHHHHHHH
ARRPGYVSPSFATIAGFNANGAMPHYRATPESHATIAGDGLLLVDSGGQYTTGTTDITRV
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCEECCCCCCEEE
VPVGTLSDLQRRDFTIVLRSMMALSRARFPRGIRSPMLDAIARAPMWAAGLDYGHGTGHG
EECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
VGYFLNVHEGPQVISHYAPAEPHTAMEEGMITSIEPGVYRPGKWGIRIENLVVNRAGGQT
EEEEEEECCCHHHHHHCCCCCCCHHHHCCCEEECCCCCCCCCCCCEEEEEEEEECCCCCC
EFGDFLAFETLTLCPIDTRCVLVEMLHEEERAWLNAYHATVRERVGRHVSGDAKAWLDAR
CHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCC
TQPI
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9733678; 11223522; 11210522 [H]