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The map label for this gene is aroK

Identifier: 115350366

GI number: 115350366

Start: 352011

End: 352565

Strand: Direct

Name: aroK

Synonym: Bamb_0311

Alternate gene names: 115350366

Gene position: 352011-352565 (Clockwise)

Preceding gene: 115350365

Following gene: 115350367

Centisome position: 9.9

GC content: 64.14

Gene sequence:

>555_bases
TTGCAAGCGCGGGACCCACACGCAAACGTATTTTTCGTCGGCCTTATGGGAGCGGGTAAGACCACCGTGGGCCGTGCGGT
CGCGCGCCGGCTCGACAGGACGTTCTTCGACTCCGACCACGAAATCGAGGCCCGCACGGGTGCGCGCATTCCGGTGATCT
TCGAGATGGAAGGCGAGGCCGGCTTTCGCGACCGCGAATCGCAGGTGATCGCGGATCTCACGCAGCGCGAGAACATCGTG
CTCGCGACGGGCGGCGGCGCGGTGTTGCGCGCCGAAAATCGCGATTGCCTGAAAGGCCACGGCATCGTCATCTATCTGCG
CGCCAATCCGCACGATCTGTGGCTGCGCACGCGCAAGGACAAGAACCGCCCGCTGTTGCAGACCGGCGACCCGAAGGCGC
GTCTCGAAGCGCTCTACGAAGTGCGCGATCCGCTGTACCGCGAATGCGCGGACTTCATCATCGAGACCGGCCGTCCGTCG
GTCAACGGCCTCGTCAACATGGTGCTGATGCAACTCGAACTCGCAGGCGTCATCGCCAAGCCGCTACAAGCATGA

Upstream 100 bases:

>100_bases
GGAAAAAGGGGGCCGGAAGCGGGTGGCGCAGGCTCGACAAGGCAGCCGCTTTGCCAGTAAGCTGCGCCACACACCAGCAA
GATTCAAGCAGAGGAAGCCG

Downstream 100 bases:

>100_bases
TTACCGTCAACGTCGACCTGGGCGAGCGCGCCTACCCGATTCACATTGGTGCCGGCCTGATCGGCCGCACCGACCTGTTC
GCCCCTCATATCACCGGTTC

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MQARDPHANVFFVGLMGAGKTTVGRAVARRLDRTFFDSDHEIEARTGARIPVIFEMEGEAGFRDRESQVIADLTQRENIV
LATGGGAVLRAENRDCLKGHGIVIYLRANPHDLWLRTRKDKNRPLLQTGDPKARLEALYEVRDPLYRECADFIIETGRPS
VNGLVNMVLMQLELAGVIAKPLQA

Sequences:

>Translated_184_residues
MQARDPHANVFFVGLMGAGKTTVGRAVARRLDRTFFDSDHEIEARTGARIPVIFEMEGEAGFRDRESQVIADLTQRENIV
LATGGGAVLRAENRDCLKGHGIVIYLRANPHDLWLRTRKDKNRPLLQTGDPKARLEALYEVRDPLYRECADFIIETGRPS
VNGLVNMVLMQLELAGVIAKPLQA
>Mature_184_residues
MQARDPHANVFFVGLMGAGKTTVGRAVARRLDRTFFDSDHEIEARTGARIPVIFEMEGEAGFRDRESQVIADLTQRENIV
LATGGGAVLRAENRDCLKGHGIVIYLRANPHDLWLRTRKDKNRPLLQTGDPKARLEALYEVRDPLYRECADFIIETGRPS
VNGLVNMVLMQLELAGVIAKPLQA

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=166, Percent_Identity=48.7951807228916, Blast_Score=160, Evalue=5e-41,
Organism=Escherichia coli, GI1786587, Length=156, Percent_Identity=39.7435897435897, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 20536; Mature: 20536

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS01128 SHIKIMATE_KINASE ; PS00267 TACHYKININ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQARDPHANVFFVGLMGAGKTTVGRAVARRLDRTFFDSDHEIEARTGARIPVIFEMEGEA
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCEEEEEECCCC
GFRDRESQVIADLTQRENIVLATGGGAVLRAENRDCLKGHGIVIYLRANPHDLWLRTRKD
CCCCCHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCCCCEEEEEECCCCEEEEEECCC
KNRPLLQTGDPKARLEALYEVRDPLYRECADFIIETGRPSVNGLVNMVLMQLELAGVIAK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
PLQA
CCCC
>Mature Secondary Structure
MQARDPHANVFFVGLMGAGKTTVGRAVARRLDRTFFDSDHEIEARTGARIPVIFEMEGEA
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCEEEEEECCCC
GFRDRESQVIADLTQRENIVLATGGGAVLRAENRDCLKGHGIVIYLRANPHDLWLRTRKD
CCCCCHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCCCCEEEEEECCCCEEEEEECCC
KNRPLLQTGDPKARLEALYEVRDPLYRECADFIIETGRPSVNGLVNMVLMQLELAGVIAK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
PLQA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA