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Identifier: 11500016

GI number: 11500016

Start: 292876

End: 293373

Strand: Reverse

Name: Not Available

Synonym: AF0323b

Alternate gene names: 11500016

Gene position: 293373-292876 (Counterclockwise)

Preceding gene: 11500015

Following gene: 11497936

Centisome position: 13.47

GC content: 53.01

Gene sequence:

>498_bases
ATGCTGCCAGGTATCGTTGTTAAACCGCTCAAAACCTTCGCAGACGAGAGGGGTTTCTTCACGGAGATAATGCGAAGAGA
CTGGGATGTTTTTGAGGATGAAATCCTTCAGGCGAACATGTCCGTGACCTATCCGGGAATCGTGAGGGCTTGGCACAAGC
ATGAGAGGGGGCAGGTGGACTACTTCGTCTGCATAGGCGGGGCGATAAAGATATGTGCCTACGATGATGAAACTCAGGAG
CTGGCAGAAATAGTTTCGACGGGCAAAAACCTTCAGGTTGTGAGGGTGCCGGGACATTACTGGCACGGCTTCAAGGCGAT
TGGGGTGGAGCCTGCAGTGCTGGTGTATTTCGTCAGCAGACTGTATGACTACGAGAATCCCGACGAGGTGAGGAGGCCCT
GGAACGACTCCACAATTGTGCCTGCAAAGATAAACGGCAGGGAAGACGACCCTCGCTGCGGAAAGCCGTGGGACTGGTTT
TATCCTCCGCATAAATGA

Upstream 100 bases:

>100_bases
AAAACTACAAACTCGAAAGAATTGGCATTAAGATGAGGCACTGGAGGGAAGCTTTAAGAGATTATTTAGCTGAGAAGGGT
TTGGTTTGATTGGTGGTAGT

Downstream 100 bases:

>100_bases
GGACTGTTTACGCAATCGTTGTGAACTACAACAATTTCGATGATACCGCTGAATGCATAGACTCCCTCTTGAACCAGACA
TATCCGTGCAGGGTAGTTGT

Product: dTDP-4-dehydrorhamnose 3,5-epimerase and related enzyme

Products: dTDP-4-dehydro-6-deoxy-L-mannose

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MLPGIVVKPLKTFADERGFFTEIMRRDWDVFEDEILQANMSVTYPGIVRAWHKHERGQVDYFVCIGGAIKICAYDDETQE
LAEIVSTGKNLQVVRVPGHYWHGFKAIGVEPAVLVYFVSRLYDYENPDEVRRPWNDSTIVPAKINGREDDPRCGKPWDWF
YPPHK

Sequences:

>Translated_165_residues
MLPGIVVKPLKTFADERGFFTEIMRRDWDVFEDEILQANMSVTYPGIVRAWHKHERGQVDYFVCIGGAIKICAYDDETQE
LAEIVSTGKNLQVVRVPGHYWHGFKAIGVEPAVLVYFVSRLYDYENPDEVRRPWNDSTIVPAKINGREDDPRCGKPWDWF
YPPHK
>Mature_165_residues
MLPGIVVKPLKTFADERGFFTEIMRRDWDVFEDEILQANMSVTYPGIVRAWHKHERGQVDYFVCIGGAIKICAYDDETQE
LAEIVSTGKNLQVVRVPGHYWHGFKAIGVEPAVLVYFVSRLYDYENPDEVRRPWNDSTIVPAKINGREDDPRCGKPWDWF
YPPHK

Specific function: Unknown

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To dTDP-4-dehydrorhamnose reductase [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: 5.1.3.13

Molecular weight: Translated: 19174; Mature: 19174

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPGIVVKPLKTFADERGFFTEIMRRDWDVFEDEILQANMSVTYPGIVRAWHKHERGQVD
CCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEE
YFVCIGGAIKICAYDDETQELAEIVSTGKNLQVVRVPGHYWHGFKAIGVEPAVLVYFVSR
EEEEECCEEEEEEECCHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCHHHHHHHHHH
LYDYENPDEVRRPWNDSTIVPAKINGREDDPRCGKPWDWFYPPHK
HHCCCCHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLPGIVVKPLKTFADERGFFTEIMRRDWDVFEDEILQANMSVTYPGIVRAWHKHERGQVD
CCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEE
YFVCIGGAIKICAYDDETQELAEIVSTGKNLQVVRVPGHYWHGFKAIGVEPAVLVYFVSR
EEEEECCEEEEEEECCHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCHHHHHHHHHH
LYDYENPDEVRRPWNDSTIVPAKINGREDDPRCGKPWDWFYPPHK
HHCCCCHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTDP-4-dehydro-6-deoxy-D-glucose

Specific reaction: dTDP-4-dehydro-6-deoxy-D-glucose = dTDP-4-dehydro-6-deoxy-L-mannose

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]