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The map label for this gene is rpl6P

Identifier: 11499493

GI number: 11499493

Start: 1717379

End: 1717969

Strand: Reverse

Name: rpl6P

Synonym: AF1909

Alternate gene names: 11499493

Gene position: 1717969-1717379 (Counterclockwise)

Preceding gene: 11499494

Following gene: 11499492

Centisome position: 78.86

GC content: 49.92

Gene sequence:

>591_bases
ATGCGAGAAAACAGAGGTTGGGAGGTGTTCTCCTTGCTTACGTCTACTGAAGTTTACGAGGAAAGAGTTGTTGAAGTGCC
GGAGGACGTGCAGCTAACCATCGAGGGAGACAGCTTCAGAGGTTACACTCTCAAGGCTGTGGGTCCGAAGGGGGAGAACA
CGAGGTATCTGAAGTACAGGGGAGTTTTCATTGAGGTTGGGGACGGGAAGGTGAGGGTTTACACAACCTCTCCCAAGAAA
AAACACAAGGCAATGGTTGGGACCTTTGCTGGGCACATCGAAAACCTCATAACCGGAGTTAAGGAAGGTTTCGAGTACCA
TCTGAAGGTTGTTTACGCTCACTTTCCCATCAAGGTCAGAGTTGAAGGTAATGAGGTTATAATCGAGAACTTCATTGGAG
AGAAGCATCCGAGAAGGGCGAAGATAGTTGGAAGGGCGCAGGTTGAGATAAGCGGTCAGGACATCTACGTGAGGGGCATA
GACATCGAAGAGTGCGGTCAGACTGCCGCGAACCTCGAACAGGCGACAAAGATCAAGAGAAAGGACCCGCGTGTTTTCCA
GGATGGGATATACATCGTAAAGAAGCCGTGA

Upstream 100 bases:

>100_bases
TCCGTCACAGAGTACGAGATGTACGAGAAAAGATACCTGCCTGCCAGGGACTTCGGGATTCTGATTGTTTCAACAACAAA
GGGTGTTATGTCGCAGAAGG

Downstream 100 bases:

>100_bases
GTGGTTGTAATGGAGCACAAAAGGCTGCTTAAGGTGAGAAGGAGGCAGAAGGCAAGAAAGCCAGAGTTCAGAAGATACTG
CTGGAACAAGAAGCTCAGAT

Product: 50S ribosomal protein L6P (rpl6P)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MRENRGWEVFSLLTSTEVYEERVVEVPEDVQLTIEGDSFRGYTLKAVGPKGENTRYLKYRGVFIEVGDGKVRVYTTSPKK
KHKAMVGTFAGHIENLITGVKEGFEYHLKVVYAHFPIKVRVEGNEVIIENFIGEKHPRRAKIVGRAQVEISGQDIYVRGI
DIEECGQTAANLEQATKIKRKDPRVFQDGIYIVKKP

Sequences:

>Translated_196_residues
MRENRGWEVFSLLTSTEVYEERVVEVPEDVQLTIEGDSFRGYTLKAVGPKGENTRYLKYRGVFIEVGDGKVRVYTTSPKK
KHKAMVGTFAGHIENLITGVKEGFEYHLKVVYAHFPIKVRVEGNEVIIENFIGEKHPRRAKIVGRAQVEISGQDIYVRGI
DIEECGQTAANLEQATKIKRKDPRVFQDGIYIVKKP
>Mature_196_residues
MRENRGWEVFSLLTSTEVYEERVVEVPEDVQLTIEGDSFRGYTLKAVGPKGENTRYLKYRGVFIEVGDGKVRVYTTSPKK
KHKAMVGTFAGHIENLITGVKEGFEYHLKVVYAHFPIKVRVEGNEVIIENFIGEKHPRRAKIVGRAQVEISGQDIYVRGI
DIEECGQTAANLEQATKIKRKDPRVFQDGIYIVKKP

Specific function: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center

COG id: COG0097

COG function: function code J; Ribosomal protein L6P/L9E

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L6P family

Homologues:

Organism=Homo sapiens, GI15431303, Length=186, Percent_Identity=34.4086021505376, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI67944630, Length=186, Percent_Identity=34.4086021505376, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI310133141, Length=166, Percent_Identity=31.9277108433735, Blast_Score=84, Evalue=6e-17,
Organism=Homo sapiens, GI310118095, Length=130, Percent_Identity=33.8461538461538, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17554746, Length=175, Percent_Identity=35.4285714285714, Blast_Score=93, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6324262, Length=186, Percent_Identity=33.8709677419355, Blast_Score=105, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6321291, Length=186, Percent_Identity=34.4086021505376, Blast_Score=105, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24583602, Length=184, Percent_Identity=33.695652173913, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI17137198, Length=184, Percent_Identity=33.695652173913, Blast_Score=100, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RL6_ARCFU (O28370)

Other databases:

- EMBL:   AE000782
- PIR:   D69488
- RefSeq:   NP_070734.1
- ProteinModelPortal:   O28370
- SMR:   O28370
- GeneID:   1485132
- GenomeReviews:   AE000782_GR
- KEGG:   afu:AF1909
- NMPDR:   fig|224325.1.peg.1895
- TIGR:   AF_1909
- HOGENOM:   HBG606796
- OMA:   QLTRIND
- ProtClustDB:   CLSK2747079
- BioCyc:   AFUL224325:AF_1909-MONOMER
- GO:   GO:0005840
- GO:   GO:0006412
- HAMAP:   MF_01365_A
- InterPro:   IPR000702
- InterPro:   IPR020040
- InterPro:   IPR002359
- InterPro:   IPR019907
- Gene3D:   G3DSA:3.90.930.12
- PANTHER:   PTHR11655
- PIRSF:   PIRSF002162
- TIGRFAMs:   TIGR03653

Pfam domain/function: PF00347 Ribosomal_L6; SSF56053 Ribosomal_L6

EC number: NA

Molecular weight: Translated: 22313; Mature: 22313

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS00700 RIBOSOMAL_L6_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRENRGWEVFSLLTSTEVYEERVVEVPEDVQLTIEGDSFRGYTLKAVGPKGENTRYLKYR
CCCCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCCCCEEEEEEE
GVFIEVGDGKVRVYTTSPKKKHKAMVGTFAGHIENLITGVKEGFEYHLKVVYAHFPIKVR
EEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCEEEE
VEGNEVIIENFIGEKHPRRAKIVGRAQVEISGQDIYVRGIDIEECGQTAANLEQATKIKR
ECCCEEEEEHHCCCCCCCCEEEEEEEEEEECCCEEEEEECCHHHHCCHHHHHHHHHHHHC
KDPRVFQDGIYIVKKP
CCCCEEECCEEEEECC
>Mature Secondary Structure
MRENRGWEVFSLLTSTEVYEERVVEVPEDVQLTIEGDSFRGYTLKAVGPKGENTRYLKYR
CCCCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCCCCEEEEEEE
GVFIEVGDGKVRVYTTSPKKKHKAMVGTFAGHIENLITGVKEGFEYHLKVVYAHFPIKVR
EEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCEEEE
VEGNEVIIENFIGEKHPRRAKIVGRAQVEISGQDIYVRGIDIEECGQTAANLEQATKIKR
ECCCEEEEEHHCCCCCCCCEEEEEEEEEEECCCEEEEEECCHHHHCCHHHHHHHHHHHHC
KDPRVFQDGIYIVKKP
CCCCEEECCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475