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Identifier: 11499401

GI number: 11499401

Start: 1626329

End: 1627678

Strand: Reverse

Name: Not Available

Synonym: AF1813

Alternate gene names: NA

Gene position: 1627678-1626329 (Counterclockwise)

Preceding gene: 11499409

Following gene: 11499397

Centisome position: 74.72

GC content: 51.56

Gene sequence:

>1350_bases
ATGGCGGGCGAAATCAGGGAAATCACCCAGACATTTGAGAGGATAAGTGCTCACTCACACATTCGCGGTCTTGGACTGGA
TGAAAATCTCAGGGCTAAGGATGTTGCCGACGGTCTTGTGGGGCAGAAGAGGGCGAGAGAGGCGGCGGGAGTTATAGTGA
GGCTCATCAAATCAGGGAAAATGGCAGGCAGGGGAATACTGATGGCAGGCCCGCCGGGAACTGGAAAAACCGCCATTGCA
GTAGCCATAAGCAAGGAGCTTGGAAAGGATATCCCATTCGTTCAGGTTTCAGCGAGCGAGTTCTACAGCGCGGAGATGAA
GAAGACTGAAGCTCTCATTCAGGCGATGAGAAAGGCAATCGGTGTGAGGATAAGAGAGACGAGGACTGTGCTTGAAGGAG
AGGTTGTTGGCCTCGACTACAACATGGTTCCCAACCCCTACAACCCCACACAGAAGATTCCTGAGTCTGCAACACTCACT
CTGGCAACAAAGGATGAGAAGAGAACCTTCAGCGTTGGGGGAAGGCTTGCGATGCAGTTCTTCACTCAAGGAATCGAGGT
TGGAGATGTCATAGTTATTGACAAGGAGACGGGGAGAATAGGGAAGCTTGGAAGGAGCGAGAAGGCGAAGAAGAAGTATG
ATCTGGGGGATGATGAGGTCGTTCCCGTCCCATCGGGAAAGGTGGAGAAGGAGAAGGAGTTCACGTATGTTGTAACATTG
CACGACCTGGATGAGGCAAATGCGAGAAGGACGAGCATATTCAGCCTCTTCTCCCCGCCGAGCAGGGAAATCGACAATGA
AGTTAGAGAAGCTGTGGATGAGCAGGTAAAGAGGCTCGTTGAGGAGGGCAGAGCTGAGCTTGTTCCGGGAGTGCTTTTTA
TCGACGAAACACATCTCATGGACATCGAGCTCTTTGCCTTCATGAACAGGGCAATGGAGTCGGAAATGGCGCCAATAATA
ATTCTCGCCTCCAACAGAGGATTTTCGAGGATTAGAGGGACCGATATTGTTGCTCCGCACGGCATCCCGCTTGACTTGCT
TGACAGGCTGCTGATCATCACGACAGAGCCCTACAGCAGGGAGGAAATCAAGACAATAATAGAGATAAGAGCAGCCGAGT
CCGGAATAATGCTCAGCAACGAGGCGATGGAGAAGCTCACTGACATAGGGGAGAAGACGAGTTTGAGGTATGCGGTTCAG
CTCCTCGCCCCAGCCTACGAGTTTGCCAAGATGAGAAACTCAGGAAAAGTGGAACTTGAGGACGTTGAGAGGGCTGCAAG
CATCTTCGCTGATGTTAGCCAGAGCTCAGCCTACCTGAAAAAGTGGGAAGAGAAGATGCTCGGCATGTGA

Upstream 100 bases:

>100_bases
TGTCCTCTGAGCTTCATGCTTTTCAGTTGTAAAGAAACAAATTTAGCTGACGGAGGAATATTTATATAGCCCTACTTTTC
CACCAATTTTGGTGGTGGCC

Downstream 100 bases:

>100_bases
TTTTAATTTTTTCTTCGGCAATGGTTTTATATTTCTAATACAAATAAATCCTGAATATGGAATTCCTAAAACAGAGGGCC
CTTCGCTTCTACTCCAAGGC

Product: TBP-interacting protein TIP49

Products: NA

Alternate protein names: TIP49 Domain Protein; TIP49-Like Protein; TIP49 Domain-Containing Protein; Tbp-Interacting Protein Tip; DNA Helicase; TIP49-Like; TBP-Interacting Proten; TIP49 C-Terminal Domain Family Protein; DNA Helicase TIP

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MAGEIREITQTFERISAHSHIRGLGLDENLRAKDVADGLVGQKRAREAAGVIVRLIKSGKMAGRGILMAGPPGTGKTAIA
VAISKELGKDIPFVQVSASEFYSAEMKKTEALIQAMRKAIGVRIRETRTVLEGEVVGLDYNMVPNPYNPTQKIPESATLT
LATKDEKRTFSVGGRLAMQFFTQGIEVGDVIVIDKETGRIGKLGRSEKAKKKYDLGDDEVVPVPSGKVEKEKEFTYVVTL
HDLDEANARRTSIFSLFSPPSREIDNEVREAVDEQVKRLVEEGRAELVPGVLFIDETHLMDIELFAFMNRAMESEMAPII
ILASNRGFSRIRGTDIVAPHGIPLDLLDRLLIITTEPYSREEIKTIIEIRAAESGIMLSNEAMEKLTDIGEKTSLRYAVQ
LLAPAYEFAKMRNSGKVELEDVERAASIFADVSQSSAYLKKWEEKMLGM

Sequences:

>Translated_449_residues
MAGEIREITQTFERISAHSHIRGLGLDENLRAKDVADGLVGQKRAREAAGVIVRLIKSGKMAGRGILMAGPPGTGKTAIA
VAISKELGKDIPFVQVSASEFYSAEMKKTEALIQAMRKAIGVRIRETRTVLEGEVVGLDYNMVPNPYNPTQKIPESATLT
LATKDEKRTFSVGGRLAMQFFTQGIEVGDVIVIDKETGRIGKLGRSEKAKKKYDLGDDEVVPVPSGKVEKEKEFTYVVTL
HDLDEANARRTSIFSLFSPPSREIDNEVREAVDEQVKRLVEEGRAELVPGVLFIDETHLMDIELFAFMNRAMESEMAPII
ILASNRGFSRIRGTDIVAPHGIPLDLLDRLLIITTEPYSREEIKTIIEIRAAESGIMLSNEAMEKLTDIGEKTSLRYAVQ
LLAPAYEFAKMRNSGKVELEDVERAASIFADVSQSSAYLKKWEEKMLGM
>Mature_448_residues
AGEIREITQTFERISAHSHIRGLGLDENLRAKDVADGLVGQKRAREAAGVIVRLIKSGKMAGRGILMAGPPGTGKTAIAV
AISKELGKDIPFVQVSASEFYSAEMKKTEALIQAMRKAIGVRIRETRTVLEGEVVGLDYNMVPNPYNPTQKIPESATLTL
ATKDEKRTFSVGGRLAMQFFTQGIEVGDVIVIDKETGRIGKLGRSEKAKKKYDLGDDEVVPVPSGKVEKEKEFTYVVTLH
DLDEANARRTSIFSLFSPPSREIDNEVREAVDEQVKRLVEEGRAELVPGVLFIDETHLMDIELFAFMNRAMESEMAPIII
LASNRGFSRIRGTDIVAPHGIPLDLLDRLLIITTEPYSREEIKTIIEIRAAESGIMLSNEAMEKLTDIGEKTSLRYAVQL
LAPAYEFAKMRNSGKVELEDVERAASIFADVSQSSAYLKKWEEKMLGM

Specific function: Unknown

COG id: COG1224

COG function: function code K; DNA helicase TIP49, TBP-interacting protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI5730023, Length=446, Percent_Identity=46.8609865470852, Blast_Score=416, Evalue=1e-116,
Organism=Homo sapiens, GI4506753, Length=452, Percent_Identity=46.9026548672566, Blast_Score=404, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17542510, Length=430, Percent_Identity=44.8837209302326, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17558290, Length=457, Percent_Identity=39.8249452954048, Blast_Score=321, Evalue=5e-88,
Organism=Saccharomyces cerevisiae, GI6325021, Length=440, Percent_Identity=45, Blast_Score=402, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6320396, Length=435, Percent_Identity=45.2873563218391, Blast_Score=380, Evalue=1e-106,
Organism=Drosophila melanogaster, GI17737635, Length=447, Percent_Identity=47.2035794183445, Blast_Score=417, Evalue=1e-117,
Organism=Drosophila melanogaster, GI21358125, Length=454, Percent_Identity=45.8149779735683, Blast_Score=370, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 49703; Mature: 49572

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGEIREITQTFERISAHSHIRGLGLDENLRAKDVADGLVGQKRAREAAGVIVRLIKSGK
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
MAGRGILMAGPPGTGKTAIAVAISKELGKDIPFVQVSASEFYSAEMKKTEALIQAMRKAI
CCCCEEEEECCCCCCCEEEEEEEEHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
GVRIRETRTVLEGEVVGLDYNMVPNPYNPTQKIPESATLTLATKDEKRTFSVGGRLAMQF
CEEEHHHHHHHCCEEEEEECCCCCCCCCCHHHCCCCCEEEEEECCCCCEEHHHHHHHHHH
FTQGIEVGDVIVIDKETGRIGKLGRSEKAKKKYDLGDDEVVPVPSGKVEKEKEFTYVVTL
HHCCCCCCCEEEEECCCCCCCCCCCCHHHHHCCCCCCCCEEECCCCCCCCCCCEEEEEEE
HDLDEANARRTSIFSLFSPPSREIDNEVREAVDEQVKRLVEEGRAELVPGVLFIDETHLM
ECCCCCCCHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEECCHHH
DIELFAFMNRAMESEMAPIIILASNRGFSRIRGTDIVAPHGIPLDLLDRLLIITTEPYSR
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEECCCCCCHHHHCCEEEEECCCCCH
EEIKTIIEIRAAESGIMLSNEAMEKLTDIGEKTSLRYAVQLLAPAYEFAKMRNSGKVELE
HHHHHHHHHHHCCCCCEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHH
DVERAASIFADVSQSSAYLKKWEEKMLGM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGEIREITQTFERISAHSHIRGLGLDENLRAKDVADGLVGQKRAREAAGVIVRLIKSGK
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
MAGRGILMAGPPGTGKTAIAVAISKELGKDIPFVQVSASEFYSAEMKKTEALIQAMRKAI
CCCCEEEEECCCCCCCEEEEEEEEHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
GVRIRETRTVLEGEVVGLDYNMVPNPYNPTQKIPESATLTLATKDEKRTFSVGGRLAMQF
CEEEHHHHHHHCCEEEEEECCCCCCCCCCHHHCCCCCEEEEEECCCCCEEHHHHHHHHHH
FTQGIEVGDVIVIDKETGRIGKLGRSEKAKKKYDLGDDEVVPVPSGKVEKEKEFTYVVTL
HHCCCCCCCEEEEECCCCCCCCCCCCHHHHHCCCCCCCCEEECCCCCCCCCCCEEEEEEE
HDLDEANARRTSIFSLFSPPSREIDNEVREAVDEQVKRLVEEGRAELVPGVLFIDETHLM
ECCCCCCCHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEECCHHH
DIELFAFMNRAMESEMAPIIILASNRGFSRIRGTDIVAPHGIPLDLLDRLLIITTEPYSR
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEECCCCCCHHHHCCEEEEECCCCCH
EEIKTIIEIRAAESGIMLSNEAMEKLTDIGEKTSLRYAVQLLAPAYEFAKMRNSGKVELE
HHHHHHHHHHHCCCCCEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHH
DVERAASIFADVSQSSAYLKKWEEKMLGM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA