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The map label for this gene is gap

Identifier: 11499321

GI number: 11499321

Start: 1554648

End: 1555670

Strand: Reverse

Name: gap

Synonym: AF1732

Alternate gene names: 11499321

Gene position: 1555670-1554648 (Counterclockwise)

Preceding gene: 11499322

Following gene: 11499320

Centisome position: 71.41

GC content: 52.98

Gene sequence:

>1023_bases
ATGATGAAGGTTAAGGTGGCGATAAACGGTTACGGAACCATCGGAAAGAGAGTGGCTGATGCAGTCAGCCTTCAGGACGA
TATGGAGGTTGTCGGAGTTACCAAAACCCGCCCAGACTTTGAGGCGAAACTCGGCGCCAAAAGGTATCCTCTCTACGTGG
CCAAGCCCGAGAACGTGGAGCTTTTCGAGAGGGCGGGGATCGAGATTCAGGGAACAATAGAGGATTTGCTGCCAAAAGCC
GACATCGTTGTCGACTGCAGCCCGAACAAGGTTGGGGCGGAAAACAAGGCGAAGTATTACGAGAAAGCGGGCATAAAGGC
GATATTCCAGGGCGGGGAGAAGAAGGACGTTGCCGAGGTCTCCTTCAACGCGCTGGCCAACTATGATGAGGCTGTTGGGA
AAAGCTACGTAAGGGTTGTGAGCTGTAACACCACCGGTTTGACGAGGCTCATTTACATGCTCAAAACGAACTTCAGCATC
GGCAGGATTAGGGCGACGATGCTGAGAAGGGTTGTCGACCCGAAGGAAGACAAGAAGGGGCTCGTCAACGGAATCATGCC
TGATCCGGTTGCGATTCCATCCCACCACGGGCCGGACGTCAAGACTGTTTTGCCCGATGTTGATATTGTAACAACAGCAT
TCAAGCTCCCCACAACGCTTATGCACGTCCACTCCCTCTGCGTTGAGATGAGAGAAGCGGTCAAAGCAGAAGACGTCGTG
AGCGCTCTCAGCGAGGAGCCGAGAATCATGCTTATTTCCGCAGAGGATGGCTTCACCTCAACGGCAAAGGTAATCGAGTT
CGCGAGAGAGCTCAGGCTCAGGTACGACCTCTACGAGAACATCGTTTGGAGGGAATCGATCGGCGTTGATGGAAACGACC
TCTTCGTAACGCAGGCGGTGCATCAGGAGGCTATTGTTGTTCCGGAGAACATTGACGCCATAAGGGCCATGTTCGAGCTT
GCGGAGAAGGAGGAGAGCATAAGGAAGACGAACGAGAGCCTTGGAATTGGGAAAGTTTTTTAA

Upstream 100 bases:

>100_bases
AAAAAGTAAAAATGTGGGACATTCTGGGAGATTACAGAGAGGTAAGAGGTAGAGTTGTTGAGATGGATTTGGTTGGGCAC
AAAATAATACTGGAGGGAGA

Downstream 100 bases:

>100_bases
AATTTTTACCTCACTTTTGCCATGGATATTCAGACGAGAAAGTCGATACTCTGGGACGCCTTTGAGGAGCTGAAAACAAG
GTGGGGTGCGGACGAAAAGT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH; NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MMKVKVAINGYGTIGKRVADAVSLQDDMEVVGVTKTRPDFEAKLGAKRYPLYVAKPENVELFERAGIEIQGTIEDLLPKA
DIVVDCSPNKVGAENKAKYYEKAGIKAIFQGGEKKDVAEVSFNALANYDEAVGKSYVRVVSCNTTGLTRLIYMLKTNFSI
GRIRATMLRRVVDPKEDKKGLVNGIMPDPVAIPSHHGPDVKTVLPDVDIVTTAFKLPTTLMHVHSLCVEMREAVKAEDVV
SALSEEPRIMLISAEDGFTSTAKVIEFARELRLRYDLYENIVWRESIGVDGNDLFVTQAVHQEAIVVPENIDAIRAMFEL
AEKEESIRKTNESLGIGKVF

Sequences:

>Translated_340_residues
MMKVKVAINGYGTIGKRVADAVSLQDDMEVVGVTKTRPDFEAKLGAKRYPLYVAKPENVELFERAGIEIQGTIEDLLPKA
DIVVDCSPNKVGAENKAKYYEKAGIKAIFQGGEKKDVAEVSFNALANYDEAVGKSYVRVVSCNTTGLTRLIYMLKTNFSI
GRIRATMLRRVVDPKEDKKGLVNGIMPDPVAIPSHHGPDVKTVLPDVDIVTTAFKLPTTLMHVHSLCVEMREAVKAEDVV
SALSEEPRIMLISAEDGFTSTAKVIEFARELRLRYDLYENIVWRESIGVDGNDLFVTQAVHQEAIVVPENIDAIRAMFEL
AEKEESIRKTNESLGIGKVF
>Mature_340_residues
MMKVKVAINGYGTIGKRVADAVSLQDDMEVVGVTKTRPDFEAKLGAKRYPLYVAKPENVELFERAGIEIQGTIEDLLPKA
DIVVDCSPNKVGAENKAKYYEKAGIKAIFQGGEKKDVAEVSFNALANYDEAVGKSYVRVVSCNTTGLTRLIYMLKTNFSI
GRIRATMLRRVVDPKEDKKGLVNGIMPDPVAIPSHHGPDVKTVLPDVDIVTTAFKLPTTLMHVHSLCVEMREAVKAEDVV
SALSEEPRIMLISAEDGFTSTAKVIEFARELRLRYDLYENIVWRESIGVDGNDLFVTQAVHQEAIVVPENIDAIRAMFEL
AEKEESIRKTNESLGIGKVF

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family

Homologues:

None

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): G3P_ARCFU (O28542)

Other databases:

- EMBL:   AE000782
- PIR:   C69466
- RefSeq:   NP_070560.1
- ProteinModelPortal:   O28542
- GeneID:   1484955
- GenomeReviews:   AE000782_GR
- KEGG:   afu:AF1732
- NMPDR:   fig|224325.1.peg.1721
- TIGR:   AF_1732
- HOGENOM:   HBG392099
- OMA:   HHGPDVQ
- ProtClustDB:   PRK04207
- BioCyc:   AFUL224325:AF_1732-MONOMER
- BRENDA:   1.2.1.59
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00559
- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006436
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR10836
- PIRSF:   PIRSF000149
- SMART:   SM00846
- TIGRFAMs:   TIGR01546

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N

EC number: =1.2.1.59

Molecular weight: Translated: 37620; Mature: 37620

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00071 GAPDH

Important sites: ACT_SITE 142-142 BINDING 112-112 BINDING 170-170 BINDING 302-302

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKVKVAINGYGTIGKRVADAVSLQDDMEVVGVTKTRPDFEAKLGAKRYPLYVAKPENVE
CEEEEEEECCCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHCCCCCCCEEEECCCCCH
LFERAGIEIQGTIEDLLPKADIVVDCSPNKVGAENKAKYYEKAGIKAIFQGGEKKDVAEV
HHHHCCCEEEECHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHCCHHHHCCCCCCCHHHH
SFNALANYDEAVGKSYVRVVSCNTTGLTRLIYMLKTNFSIGRIRATMLRRVVDPKEDKKG
HHHHHHCHHHHHCCCEEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHH
LVNGIMPDPVAIPSHHGPDVKTVLPDVDIVTTAFKLPTTLMHVHSLCVEMREAVKAEDVV
HHCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SALSEEPRIMLISAEDGFTSTAKVIEFARELRLRYDLYENIVWRESIGVDGNDLFVTQAV
HHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEC
HQEAIVVPENIDAIRAMFELAEKEESIRKTNESLGIGKVF
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MMKVKVAINGYGTIGKRVADAVSLQDDMEVVGVTKTRPDFEAKLGAKRYPLYVAKPENVE
CEEEEEEECCCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHCCCCCCCEEEECCCCCH
LFERAGIEIQGTIEDLLPKADIVVDCSPNKVGAENKAKYYEKAGIKAIFQGGEKKDVAEV
HHHHCCCEEEECHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHCCHHHHCCCCCCCHHHH
SFNALANYDEAVGKSYVRVVSCNTTGLTRLIYMLKTNFSIGRIRATMLRRVVDPKEDKKG
HHHHHHCHHHHHCCCEEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHH
LVNGIMPDPVAIPSHHGPDVKTVLPDVDIVTTAFKLPTTLMHVHSLCVEMREAVKAEDVV
HHCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SALSEEPRIMLISAEDGFTSTAKVIEFARELRLRYDLYENIVWRESIGVDGNDLFVTQAV
HHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEC
HQEAIVVPENIDAIRAMFELAEKEESIRKTNESLGIGKVF
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475