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Identifier: 11499068

GI number: 11499068

Start: 1333887

End: 1334288

Strand: Reverse

Name: Not Available

Synonym: AF1473

Alternate gene names: 11499068

Gene position: 1334288-1333887 (Counterclockwise)

Preceding gene: 11499069

Following gene: 11499067

Centisome position: 61.25

GC content: 43.78

Gene sequence:

>402_bases
ATGGACAGAATCCTGCTGGTTGAGGATAATCCAGACGATGTTTTCATGATTAAGAGGGCTTTTGAGAAGGCCAAGATAAT
CAATCCCCTTGATGTGGCGAAGGATGGGGAGGAGGCGATAAGCTACCTGCAAGAAAACAAGCCCGTGCTGATTCTCCTTG
ACTTAAAGCTTCCAAAGGTTTCGGGTTTTGAAGTTCTGAAGTGGGTTAAATCGAAGGAAAGGCTGAAGAGGATTCCCGTG
GTTGTTTTAACTTCATCAAGAAATGGAGAGGACATAAACAGAGCTTACGACCTCGGAGCAAACTCCTACCTTGTGAAGCC
TGTCCGCTTTGAGGATTTACTGAATCTCACCAAACATATGAATATTTACTGGCTAATTCTTAATGAGAAACCGGAGGTTT
GA

Upstream 100 bases:

>100_bases
GAAAGTTTTTGATTATGTTGGCGGAGCAGCGGTAATCACACGAAAAATATTTAATTTTGAATGGGATAGTGTCAATCGCA
GGATAATCAGAGGTGTGAAG

Downstream 100 bases:

>100_bases
GATGAGAATACTTATAGCCGATGACAACCCGGATGACAGAATTCTGGCTGTGAGAGAGCTTAAAAAAGAGTTTGCGGATT
TGGAAGTGGTTGAAATACTC

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MDRILLVEDNPDDVFMIKRAFEKAKIINPLDVAKDGEEAISYLQENKPVLILLDLKLPKVSGFEVLKWVKSKERLKRIPV
VVLTSSRNGEDINRAYDLGANSYLVKPVRFEDLLNLTKHMNIYWLILNEKPEV

Sequences:

>Translated_133_residues
MDRILLVEDNPDDVFMIKRAFEKAKIINPLDVAKDGEEAISYLQENKPVLILLDLKLPKVSGFEVLKWVKSKERLKRIPV
VVLTSSRNGEDINRAYDLGANSYLVKPVRFEDLLNLTKHMNIYWLILNEKPEV
>Mature_133_residues
MDRILLVEDNPDDVFMIKRAFEKAKIINPLDVAKDGEEAISYLQENKPVLILLDLKLPKVSGFEVLKWVKSKERLKRIPV
VVLTSSRNGEDINRAYDLGANSYLVKPVRFEDLLNLTKHMNIYWLILNEKPEV

Specific function: Forms a two-component system with cph1 in which it acts as receiver substrate [H]

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=112, Percent_Identity=33.0357142857143, Blast_Score=67, Evalue=6e-13,
Organism=Escherichia coli, GI1786599, Length=116, Percent_Identity=36.2068965517241, Blast_Score=60, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 15406; Mature: 15406

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRILLVEDNPDDVFMIKRAFEKAKIINPLDVAKDGEEAISYLQENKPVLILLDLKLPKV
CCEEEEEECCCCCEEHHHHHHHHHHCCCCHHCCCCHHHHHHHHHCCCCEEEEEECCCCCC
SGFEVLKWVKSKERLKRIPVVVLTSSRNGEDINRAYDLGANSYLVKPVRFEDLLNLTKHM
CCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHCCCCCEEECCCCHHHHHHHHHCC
NIYWLILNEKPEV
EEEEEEECCCCCC
>Mature Secondary Structure
MDRILLVEDNPDDVFMIKRAFEKAKIINPLDVAKDGEEAISYLQENKPVLILLDLKLPKV
CCEEEEEECCCCCEEHHHHHHHHHHCCCCHHCCCCHHHHHHHHHCCCCEEEEEECCCCCC
SGFEVLKWVKSKERLKRIPVVVLTSSRNGEDINRAYDLGANSYLVKPVRFEDLLNLTKHM
CCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHCCCCCEEECCCCHHHHHHHHHCC
NIYWLILNEKPEV
EEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9278513 [H]