BacMap

Definition	Archaeoglobus fulgidus DSM 4304, complete genome.
Accession	NC_000917
Length	2,178,400

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The map label for this gene is cdc48-1

Identifier: 11498895

GI number: 11498895

Start: 1156904

End: 1159105

Strand: Reverse

Name: cdc48-1

Synonym: AF1297

Alternate gene names: 11498895

Gene position: 1159105-1156904 (Counterclockwise)

Preceding gene: 11498896

Following gene: 11498894

Centisome position: 53.21

GC content: 53.91

Gene sequence:

>2202_bases
ATGAGTGATAAAAAAGGTGAGGAAATAACCCTTAGAGTTGCTGAAGCTTTCTATCGCGATGTTGGAAGGGGTGTTGCCAG
AATCGATCCAGCAGTGATGGAAAAGTACGGACTGCAGAGCGGTGACATAATAGAGATTATAGGAAAGAGCACCGTTCCAG
CAATAGTCTGGCCGAGCTATCCGGAGGATAGGGGAACCGGAATAATAAGGATTGATGGCAGCATTAGAAGCAACGCAGGC
GTTGGTATTGATGACAAAGTCAGAATAAGGAAGGTTACAGCAAAGCCAGCAGAGAAAGTTACACTCGCTCCAACAGAGCC
GGTAAGGCTGATGGGTGGCGAGGCGTATCTGCTGAGGCTGCTTGAAGGCAGACCGGTCATCAAAGGTCAGAAAATCAGGG
TTGAGGTTTTCGGTCACACTCTGACGTTCGTAATAACCGCCACCAGGCCCTCAGGAGTCGTCGTTGTCACGAGAAACACT
GCGATCGAGCTTAAGGAGAAGCCGGCCGAGGAGGTAAAGAGGGCTGTTCCTGACGTAACTTATGAGGACATAGGCGGTCT
GAAGAGGGAGCTTAGGCTGGTCAGAGAGATGATAGAGCTTCCATTGAAGCATCCCGAGCTCTTCCAGAGGCTCGGAATCG
AGCCGCCCAAGGGTGTGCTGCTCTACGGTCCGCCGGGAACTGGAAAAACGCTGATTGCCAAGGCTGTGGCGAATGAGGTG
GACGCGCACTTCATACCCATCAGCGGGCCGGAAATCATGAGCAAGTACTATGGAGAGAGCGAGCAGAGGCTGAGGGAGAT
TTTCGAGGAGGCTAAGGAGAACGCTCCGTCGATAATCTTCATAGACGAAATCGACTCAATTGCTCCTAAGAGAGAAGAGG
TCACCGGAGAAGTTGAGAGAAGGGTCGTCGCCCAGCTGCTGGCGCTGATGGACGGGCTTGAGGCAAGAGGAGACGTCATA
GTCATTGCCGCTACAAACAGGCCTGACGCGATCGATCCTGCACTGAGAAGGCCGGGAAGGTTCGACAGGGAGATTGAGAT
CGGAGTTCCGGACAAGGAGGGCAGGAAGGAGATTCTCGAGATTCACACCAGAAAGATGCCCCTCGCCGAGGATGTTGACC
TTGAAGAGCTTGCCGAGCTGACAAACGGATTTGTTGGAGCGGATCTGGAAGCACTGTGCAAGGAAGCAGCGATGCACGCC
TTGAGGAGAGTTCTGCCGGAGATAGACATCGAGGCCGAGGAAATTCCCGCAGAGGTCATTGAGAATCTCAAAGTCACGAG
GGAGGACTTCATGGAGGCTCTGAAGAACATCGAGCCGTCTGCGATGAGAGAGGTGCTGGTGGAGGTGCCCAACGTCAAGT
GGGAGGACATCGGTGGACTTGAGCATGCTAAGCAGGAGCTGATGGAGGCAGTTGAATGGCCATTGAAGTATCCGGAGGTG
TTCAGGGCAGCAAACATCAAGCCGCCGAGGGGAATACTGCTGTTCGGCCCACCCGGAACGGGTAAGACCTTGCTGGCTAA
GGCTGTGGCAAACGAGAGCAATGCGAACTTCATCAGCGTGAAGGGGCCTGAGCTGCTGAGCAAGTGGGTTGGTGAGAGCG
AGAAGCACGTCAGGGAGATGTTCAGGAAGGCAAGGCAGGTAGCTCCGTGTGTCATATTCTTCGACGAGATCGACAGCCTT
GCCCCCAGAAGAGGCGGAATTGGCGATTCACACGTCACTGAGAGAGTTGTGAGCCAGCTCCTGACGGAGCTCGACGGACT
GGAGGAGCTCAAAGATGTGGTGGTCATAGCCGCCACCAACAGGCCGGACATGATTGATCCAGCGCTGCTCAGACCCGGAA
GGCTTGAAAGGCACATCTACATACCTCCACCCGACAAGAAGGCGAGAGTGGAGATATTCAAGATACACCTCAGAGGAAAA
CCGCTTGCGGATGACGTGAACATCGAAGAGCTTGCGGAGAAGACGGAGGGATACAGCGGAGCGGACATCGAGGCAGTGTG
CAGGGAGGCAGGAATGCTCGCAATCAGGGAGCTCATCAAGCCGGGTATGACGAGAGAGGAGGCTAAAGAGGCGGCGAAGA
AGCTCAAGATTACGAAGAAGCACTTTGAGGAAGCGCTGAAAAAGGTCAGGCCGAGCCTAACCAAGGAGGACGTTGAGAAG
TATGAGAAGTTGATTGAAGATTTCCACAGGATGTACGCTTAA

Upstream 100 bases:

>100_bases
TTGAAAGAGCCCTAAACTCCCTTCACGAAAAGGGGTTGGTTGAGAAAGAGGAAAAGAATGGTGAAGTTGTTTGGATGATA
AAGTAAGGAGGTGGTAGAAG

Downstream 100 bases:

>100_bases
AGGAGGTGAGGTTGTATGGTTTGGAGGAGAAGGAGAAGGGACTGGGATGAGGAATGGGACATCTTCGATGAGTTCTTCAG
ATTCGGCATAGACGACATAT

Product: cell division protein CDC48

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 733; Mature: 732

Protein sequence:

>733_residues
MSDKKGEEITLRVAEAFYRDVGRGVARIDPAVMEKYGLQSGDIIEIIGKSTVPAIVWPSYPEDRGTGIIRIDGSIRSNAG
VGIDDKVRIRKVTAKPAEKVTLAPTEPVRLMGGEAYLLRLLEGRPVIKGQKIRVEVFGHTLTFVITATRPSGVVVVTRNT
AIELKEKPAEEVKRAVPDVTYEDIGGLKRELRLVREMIELPLKHPELFQRLGIEPPKGVLLYGPPGTGKTLIAKAVANEV
DAHFIPISGPEIMSKYYGESEQRLREIFEEAKENAPSIIFIDEIDSIAPKREEVTGEVERRVVAQLLALMDGLEARGDVI
VIAATNRPDAIDPALRRPGRFDREIEIGVPDKEGRKEILEIHTRKMPLAEDVDLEELAELTNGFVGADLEALCKEAAMHA
LRRVLPEIDIEAEEIPAEVIENLKVTREDFMEALKNIEPSAMREVLVEVPNVKWEDIGGLEHAKQELMEAVEWPLKYPEV
FRAANIKPPRGILLFGPPGTGKTLLAKAVANESNANFISVKGPELLSKWVGESEKHVREMFRKARQVAPCVIFFDEIDSL
APRRGGIGDSHVTERVVSQLLTELDGLEELKDVVVIAATNRPDMIDPALLRPGRLERHIYIPPPDKKARVEIFKIHLRGK
PLADDVNIEELAEKTEGYSGADIEAVCREAGMLAIRELIKPGMTREEAKEAAKKLKITKKHFEEALKKVRPSLTKEDVEK
YEKLIEDFHRMYA

Sequences:

>Translated_733_residues
MSDKKGEEITLRVAEAFYRDVGRGVARIDPAVMEKYGLQSGDIIEIIGKSTVPAIVWPSYPEDRGTGIIRIDGSIRSNAG
VGIDDKVRIRKVTAKPAEKVTLAPTEPVRLMGGEAYLLRLLEGRPVIKGQKIRVEVFGHTLTFVITATRPSGVVVVTRNT
AIELKEKPAEEVKRAVPDVTYEDIGGLKRELRLVREMIELPLKHPELFQRLGIEPPKGVLLYGPPGTGKTLIAKAVANEV
DAHFIPISGPEIMSKYYGESEQRLREIFEEAKENAPSIIFIDEIDSIAPKREEVTGEVERRVVAQLLALMDGLEARGDVI
VIAATNRPDAIDPALRRPGRFDREIEIGVPDKEGRKEILEIHTRKMPLAEDVDLEELAELTNGFVGADLEALCKEAAMHA
LRRVLPEIDIEAEEIPAEVIENLKVTREDFMEALKNIEPSAMREVLVEVPNVKWEDIGGLEHAKQELMEAVEWPLKYPEV
FRAANIKPPRGILLFGPPGTGKTLLAKAVANESNANFISVKGPELLSKWVGESEKHVREMFRKARQVAPCVIFFDEIDSL
APRRGGIGDSHVTERVVSQLLTELDGLEELKDVVVIAATNRPDMIDPALLRPGRLERHIYIPPPDKKARVEIFKIHLRGK
PLADDVNIEELAEKTEGYSGADIEAVCREAGMLAIRELIKPGMTREEAKEAAKKLKITKKHFEEALKKVRPSLTKEDVEK
YEKLIEDFHRMYA
>Mature_732_residues
SDKKGEEITLRVAEAFYRDVGRGVARIDPAVMEKYGLQSGDIIEIIGKSTVPAIVWPSYPEDRGTGIIRIDGSIRSNAGV
GIDDKVRIRKVTAKPAEKVTLAPTEPVRLMGGEAYLLRLLEGRPVIKGQKIRVEVFGHTLTFVITATRPSGVVVVTRNTA
IELKEKPAEEVKRAVPDVTYEDIGGLKRELRLVREMIELPLKHPELFQRLGIEPPKGVLLYGPPGTGKTLIAKAVANEVD
AHFIPISGPEIMSKYYGESEQRLREIFEEAKENAPSIIFIDEIDSIAPKREEVTGEVERRVVAQLLALMDGLEARGDVIV
IAATNRPDAIDPALRRPGRFDREIEIGVPDKEGRKEILEIHTRKMPLAEDVDLEELAELTNGFVGADLEALCKEAAMHAL
RRVLPEIDIEAEEIPAEVIENLKVTREDFMEALKNIEPSAMREVLVEVPNVKWEDIGGLEHAKQELMEAVEWPLKYPEVF
RAANIKPPRGILLFGPPGTGKTLLAKAVANESNANFISVKGPELLSKWVGESEKHVREMFRKARQVAPCVIFFDEIDSLA
PRRGGIGDSHVTERVVSQLLTELDGLEELKDVVVIAATNRPDMIDPALLRPGRLERHIYIPPPDKKARVEIFKIHLRGKP
LADDVNIEELAEKTEGYSGADIEAVCREAGMLAIRELIKPGMTREEAKEAAKKLKITKKHFEEALKKVRPSLTKEDVEKY
EKLIEDFHRMYA

Specific function: Seems To Act As An ATP-Dependent Zinc Metallopeptidase. Involved In The Degradation Of Sigma-32. Degrades Carboxy- Terminal-Tagged Cytoplasmic Proteins. These Proteins Are Tagged With An 11-Amino-Acid Nonpolar Destabilizing Tail VIa A Mechanism Involving

COG id: COG0464

COG function: function code O; ATPases of the AAA+ class

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AAA ATPase family. CDC48 subfamily

Homologues:

Organism=Homo sapiens, GI6005942, Length=762, Percent_Identity=47.244094488189, Blast_Score=665, Evalue=0.0,
Organism=Homo sapiens, GI157671927, Length=557, Percent_Identity=54.0394973070018, Blast_Score=603, Evalue=1e-172,
Organism=Homo sapiens, GI45643125, Length=619, Percent_Identity=47.172859450727, Blast_Score=545, Evalue=1e-155,
Organism=Homo sapiens, GI45643123, Length=619, Percent_Identity=47.172859450727, Blast_Score=544, Evalue=1e-154,
Organism=Homo sapiens, GI229577436, Length=774, Percent_Identity=38.7596899224806, Blast_Score=462, Evalue=1e-130,
Organism=Homo sapiens, GI4505725, Length=541, Percent_Identity=36.9685767097967, Blast_Score=318, Evalue=8e-87,
Organism=Homo sapiens, GI194018488, Length=526, Percent_Identity=35.9315589353612, Blast_Score=298, Evalue=1e-80,
Organism=Homo sapiens, GI153792536, Length=274, Percent_Identity=47.4452554744526, Blast_Score=265, Evalue=1e-70,
Organism=Homo sapiens, GI24497618, Length=273, Percent_Identity=47.2527472527472, Blast_Score=265, Evalue=1e-70,
Organism=Homo sapiens, GI24430151, Length=264, Percent_Identity=47.3484848484849, Blast_Score=248, Evalue=1e-65,
Organism=Homo sapiens, GI24497435, Length=230, Percent_Identity=53.9130434782609, Blast_Score=244, Evalue=3e-64,
Organism=Homo sapiens, GI5901990, Length=311, Percent_Identity=45.9807073954984, Blast_Score=243, Evalue=5e-64,
Organism=Homo sapiens, GI14149767, Length=311, Percent_Identity=45.3376205787781, Blast_Score=240, Evalue=4e-63,
Organism=Homo sapiens, GI62177112, Length=311, Percent_Identity=45.3376205787781, Blast_Score=240, Evalue=4e-63,
Organism=Homo sapiens, GI4506209, Length=229, Percent_Identity=50.6550218340611, Blast_Score=236, Evalue=4e-62,
Organism=Homo sapiens, GI21361144, Length=300, Percent_Identity=43, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI195539395, Length=266, Percent_Identity=44.7368421052632, Blast_Score=234, Evalue=3e-61,
Organism=Homo sapiens, GI5729991, Length=229, Percent_Identity=49.7816593886463, Blast_Score=230, Evalue=4e-60,
Organism=Homo sapiens, GI89064750, Length=229, Percent_Identity=49.7816593886463, Blast_Score=230, Evalue=4e-60,
Organism=Homo sapiens, GI24430155, Length=229, Percent_Identity=49.7816593886463, Blast_Score=230, Evalue=5e-60,
Organism=Homo sapiens, GI300192933, Length=281, Percent_Identity=44.8398576512456, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI31742536, Length=306, Percent_Identity=41.8300653594771, Blast_Score=216, Evalue=7e-56,
Organism=Homo sapiens, GI112789543, Length=306, Percent_Identity=41.8300653594771, Blast_Score=216, Evalue=7e-56,
Organism=Homo sapiens, GI156564401, Length=436, Percent_Identity=36.0091743119266, Blast_Score=215, Evalue=1e-55,
Organism=Homo sapiens, GI7019569, Length=247, Percent_Identity=46.1538461538462, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI17865802, Length=247, Percent_Identity=44.1295546558704, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI226371754, Length=298, Percent_Identity=37.9194630872483, Blast_Score=196, Evalue=6e-50,
Organism=Homo sapiens, GI11875211, Length=306, Percent_Identity=39.2156862745098, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI40806170, Length=306, Percent_Identity=39.2156862745098, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI4507173, Length=287, Percent_Identity=39.0243902439024, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI21327685, Length=224, Percent_Identity=46.4285714285714, Blast_Score=191, Evalue=3e-48,
Organism=Homo sapiens, GI7657689, Length=224, Percent_Identity=46.4285714285714, Blast_Score=191, Evalue=3e-48,
Organism=Homo sapiens, GI310125282, Length=281, Percent_Identity=41.2811387900356, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI310125280, Length=272, Percent_Identity=41.5441176470588, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI31377644, Length=306, Percent_Identity=32.6797385620915, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI64084766, Length=308, Percent_Identity=33.1168831168831, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI116292174, Length=308, Percent_Identity=26.9480519480519, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI40806173, Length=138, Percent_Identity=42.7536231884058, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI11321607, Length=237, Percent_Identity=30.379746835443, Blast_Score=84, Evalue=6e-16,
Organism=Escherichia coli, GI1789568, Length=239, Percent_Identity=46.8619246861925, Blast_Score=213, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI17532375, Length=734, Percent_Identity=47.5476839237057, Blast_Score=666, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17531535, Length=733, Percent_Identity=46.2482946793997, Blast_Score=651, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17537217, Length=609, Percent_Identity=41.3793103448276, Blast_Score=440, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI17508053, Length=568, Percent_Identity=37.1478873239437, Blast_Score=321, Evalue=1e-87,
Organism=Caenorhabditis elegans, GI133931034, Length=278, Percent_Identity=44.6043165467626, Blast_Score=247, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI193206116, Length=278, Percent_Identity=44.6043165467626, Blast_Score=247, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI193206114, Length=278, Percent_Identity=44.6043165467626, Blast_Score=247, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17554786, Length=275, Percent_Identity=44.7272727272727, Blast_Score=243, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI25153574, Length=482, Percent_Identity=34.4398340248963, Blast_Score=243, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI17563250, Length=264, Percent_Identity=45.4545454545455, Blast_Score=242, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI71987364, Length=263, Percent_Identity=44.8669201520913, Blast_Score=241, Evalue=9e-64,
Organism=Caenorhabditis elegans, GI71987372, Length=263, Percent_Identity=45.2471482889734, Blast_Score=241, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17562804, Length=495, Percent_Identity=33.3333333333333, Blast_Score=240, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI25144281, Length=230, Percent_Identity=52.1739130434783, Blast_Score=238, Evalue=8e-63,
Organism=Caenorhabditis elegans, GI25144278, Length=230, Percent_Identity=52.1739130434783, Blast_Score=238, Evalue=8e-63,
Organism=Caenorhabditis elegans, GI17563248, Length=229, Percent_Identity=48.9082969432314, Blast_Score=231, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17508701, Length=300, Percent_Identity=41.3333333333333, Blast_Score=228, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI193209502, Length=227, Percent_Identity=49.3392070484581, Blast_Score=226, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI17505546, Length=230, Percent_Identity=48.695652173913, Blast_Score=225, Evalue=6e-59,
Organism=Caenorhabditis elegans, GI17554784, Length=229, Percent_Identity=49.3449781659389, Blast_Score=221, Evalue=9e-58,
Organism=Caenorhabditis elegans, GI71994521, Length=286, Percent_Identity=43.3566433566434, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI86561515, Length=237, Percent_Identity=44.7257383966245, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI25146157, Length=286, Percent_Identity=38.8111888111888, Blast_Score=192, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI133901662, Length=422, Percent_Identity=34.1232227488152, Blast_Score=189, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17508421, Length=283, Percent_Identity=40.6360424028269, Blast_Score=189, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI133901658, Length=422, Percent_Identity=33.8862559241706, Blast_Score=188, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI32563584, Length=286, Percent_Identity=40.2097902097902, Blast_Score=187, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17554264, Length=215, Percent_Identity=40.9302325581395, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17560432, Length=288, Percent_Identity=37.5, Blast_Score=169, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17541224, Length=256, Percent_Identity=36.71875, Blast_Score=168, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI115534323, Length=233, Percent_Identity=41.2017167381974, Blast_Score=168, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI17541226, Length=256, Percent_Identity=36.71875, Blast_Score=168, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI17570397, Length=103, Percent_Identity=43.6893203883495, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI32566590, Length=103, Percent_Identity=43.6893203883495, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71990294, Length=144, Percent_Identity=30.5555555555556, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17533043, Length=213, Percent_Identity=28.6384976525822, Blast_Score=69, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320077, Length=752, Percent_Identity=46.8085106382979, Blast_Score=651, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323429, Length=744, Percent_Identity=41.2634408602151, Blast_Score=542, Evalue=1e-155,
Organism=Saccharomyces cerevisiae, GI6322994, Length=624, Percent_Identity=42.6282051282051, Blast_Score=484, Evalue=1e-137,
Organism=Saccharomyces cerevisiae, GI6322651, Length=492, Percent_Identity=34.1463414634146, Blast_Score=275, Evalue=3e-74,
Organism=Saccharomyces cerevisiae, GI6324000, Length=587, Percent_Identity=31.3458262350937, Blast_Score=261, Evalue=4e-70,
Organism=Saccharomyces cerevisiae, GI6321709, Length=278, Percent_Identity=48.5611510791367, Blast_Score=260, Evalue=6e-70,
Organism=Saccharomyces cerevisiae, GI6321390, Length=231, Percent_Identity=53.2467532467532, Blast_Score=249, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6320197, Length=273, Percent_Identity=46.8864468864469, Blast_Score=242, Evalue=1e-64,
Organism=Saccharomyces cerevisiae, GI6324833, Length=230, Percent_Identity=51.304347826087, Blast_Score=229, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6322704, Length=229, Percent_Identity=48.0349344978166, Blast_Score=227, Evalue=6e-60,
Organism=Saccharomyces cerevisiae, GI6319554, Length=410, Percent_Identity=36.5853658536585, Blast_Score=226, Evalue=9e-60,
Organism=Saccharomyces cerevisiae, GI6325431, Length=317, Percent_Identity=41.3249211356467, Blast_Score=221, Evalue=5e-58,
Organism=Saccharomyces cerevisiae, GI6320602, Length=261, Percent_Identity=45.5938697318008, Blast_Score=220, Evalue=8e-58,
Organism=Saccharomyces cerevisiae, GI6324691, Length=265, Percent_Identity=44.1509433962264, Blast_Score=218, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6320854, Length=292, Percent_Identity=40.7534246575342, Blast_Score=200, Evalue=6e-52,
Organism=Saccharomyces cerevisiae, GI6325183, Length=319, Percent_Identity=37.6175548589342, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6323736, Length=263, Percent_Identity=42.5855513307985, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6325281, Length=277, Percent_Identity=37.9061371841155, Blast_Score=191, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6320887, Length=365, Percent_Identity=33.972602739726, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6321465, Length=232, Percent_Identity=41.8103448275862, Blast_Score=186, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6320583, Length=200, Percent_Identity=28, Blast_Score=78, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI9755327, Length=183, Percent_Identity=30.0546448087432, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17137560, Length=768, Percent_Identity=47.3958333333333, Blast_Score=666, Evalue=0.0,
Organism=Drosophila melanogaster, GI161076486, Length=733, Percent_Identity=48.2946793997271, Blast_Score=663, Evalue=0.0,
Organism=Drosophila melanogaster, GI161076488, Length=724, Percent_Identity=48.6187845303867, Blast_Score=661, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921202, Length=723, Percent_Identity=37.2060857538036, Blast_Score=432, Evalue=1e-121,
Organism=Drosophila melanogaster, GI45552965, Length=308, Percent_Identity=50, Blast_Score=308, Evalue=9e-84,
Organism=Drosophila melanogaster, GI281365776, Length=307, Percent_Identity=49.5114006514658, Blast_Score=308, Evalue=9e-84,
Organism=Drosophila melanogaster, GI24660075, Length=308, Percent_Identity=50, Blast_Score=308, Evalue=1e-83,
Organism=Drosophila melanogaster, GI21355121, Length=529, Percent_Identity=35.1606805293006, Blast_Score=306, Evalue=4e-83,
Organism=Drosophila melanogaster, GI24652279, Length=258, Percent_Identity=51.5503875968992, Blast_Score=270, Evalue=2e-72,
Organism=Drosophila melanogaster, GI281363136, Length=585, Percent_Identity=32.8205128205128, Blast_Score=267, Evalue=2e-71,
Organism=Drosophila melanogaster, GI78707192, Length=585, Percent_Identity=32.8205128205128, Blast_Score=267, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24656825, Length=533, Percent_Identity=31.7073170731707, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24656820, Length=552, Percent_Identity=30.6159420289855, Blast_Score=260, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24649446, Length=264, Percent_Identity=46.969696969697, Blast_Score=246, Evalue=5e-65,
Organism=Drosophila melanogaster, GI19920408, Length=230, Percent_Identity=53.4782608695652, Blast_Score=244, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24651451, Length=268, Percent_Identity=47.0149253731343, Blast_Score=243, Evalue=3e-64,
Organism=Drosophila melanogaster, GI18860063, Length=229, Percent_Identity=51.0917030567686, Blast_Score=242, Evalue=8e-64,
Organism=Drosophila melanogaster, GI24640100, Length=263, Percent_Identity=46.7680608365019, Blast_Score=239, Evalue=7e-63,
Organism=Drosophila melanogaster, GI17137738, Length=229, Percent_Identity=49.7816593886463, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI17738151, Length=300, Percent_Identity=42.3333333333333, Blast_Score=234, Evalue=2e-61,
Organism=Drosophila melanogaster, GI281361487, Length=229, Percent_Identity=48.471615720524, Blast_Score=234, Evalue=2e-61,
Organism=Drosophila melanogaster, GI24644145, Length=293, Percent_Identity=44.7098976109215, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24663015, Length=263, Percent_Identity=45.2471482889734, Blast_Score=228, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24665814, Length=269, Percent_Identity=44.2379182156134, Blast_Score=219, Evalue=7e-57,
Organism=Drosophila melanogaster, GI28574878, Length=269, Percent_Identity=44.2379182156134, Blast_Score=219, Evalue=8e-57,
Organism=Drosophila melanogaster, GI281360146, Length=293, Percent_Identity=40.9556313993174, Blast_Score=216, Evalue=4e-56,
Organism=Drosophila melanogaster, GI281360138, Length=293, Percent_Identity=40.9556313993174, Blast_Score=216, Evalue=4e-56,
Organism=Drosophila melanogaster, GI281360142, Length=293, Percent_Identity=40.9556313993174, Blast_Score=216, Evalue=6e-56,
Organism=Drosophila melanogaster, GI21357333, Length=293, Percent_Identity=40.9556313993174, Blast_Score=216, Evalue=6e-56,
Organism=Drosophila melanogaster, GI281360136, Length=293, Percent_Identity=40.9556313993174, Blast_Score=215, Evalue=9e-56,
Organism=Drosophila melanogaster, GI24644411, Length=293, Percent_Identity=40.9556313993174, Blast_Score=215, Evalue=9e-56,
Organism=Drosophila melanogaster, GI281360144, Length=293, Percent_Identity=40.9556313993174, Blast_Score=215, Evalue=9e-56,
Organism=Drosophila melanogaster, GI281360140, Length=293, Percent_Identity=40.9556313993174, Blast_Score=215, Evalue=9e-56,
Organism=Drosophila melanogaster, GI28573010, Length=398, Percent_Identity=37.6884422110553, Blast_Score=211, Evalue=1e-54,
Organism=Drosophila melanogaster, GI17864540, Length=436, Percent_Identity=35.3211009174312, Blast_Score=211, Evalue=2e-54,
Organism=Drosophila melanogaster, GI18859657, Length=321, Percent_Identity=38.3177570093458, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24581396, Length=281, Percent_Identity=41.6370106761566, Blast_Score=202, Evalue=5e-52,
Organism=Drosophila melanogaster, GI24658770, Length=224, Percent_Identity=47.3214285714286, Blast_Score=198, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24639391, Length=232, Percent_Identity=44.3965517241379, Blast_Score=190, Evalue=3e-48,
Organism=Drosophila melanogaster, GI20129423, Length=268, Percent_Identity=38.0597014925373, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI28571849, Length=305, Percent_Identity=37.0491803278689, Blast_Score=181, Evalue=2e-45,
Organism=Drosophila melanogaster, GI28571847, Length=305, Percent_Identity=37.0491803278689, Blast_Score=181, Evalue=2e-45,
Organism=Drosophila melanogaster, GI20129529, Length=280, Percent_Identity=36.7857142857143, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24639486, Length=351, Percent_Identity=32.4786324786325, Blast_Score=158, Evalue=1e-38,
Organism=Drosophila melanogaster, GI45554047, Length=166, Percent_Identity=42.1686746987952, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28573181, Length=199, Percent_Identity=31.6582914572864, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI20129417, Length=189, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24583262, Length=189, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1297_ARCFU (O28972)

Other databases:

- EMBL:   AE000782
- PIR:   H69411
- RefSeq:   NP_070126.1
- ProteinModelPortal:   O28972
- GeneID:   1484523
- GenomeReviews:   AE000782_GR
- KEGG:   afu:AF1297
- NMPDR:   fig|224325.1.peg.1286
- TIGR:   AF_1297
- HOGENOM:   HBG597299
- OMA:   YLADVTH
- ProtClustDB:   CLSK2746840
- BioCyc:   AFUL224325:AF_1297-MONOMER
- InterPro:   IPR009010
- InterPro:   IPR003593
- InterPro:   IPR005938
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR003338
- InterPro:   IPR004201
- InterPro:   IPR015415
- Gene3D:   G3DSA:2.40.40.20
- SMART:   SM00382
- TIGRFAMs:   TIGR01243

Pfam domain/function: PF00004 AAA; PF02933 CDC48_2; PF02359 CDC48_N; PF09336 Vps4_C; SSF50692 Asp_decarb_fold

EC number: 3.4.24.- [C]

Molecular weight: Translated: 81793; Mature: 81662

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKKGEEITLRVAEAFYRDVGRGVARIDPAVMEKYGLQSGDIIEIIGKSTVPAIVWPSY
CCCCCCCEEEHHHHHHHHHHHCCCHHHCCHHHHHHHCCCCCCEEEEECCCCCCEEECCCC
PEDRGTGIIRIDGSIRSNAGVGIDDKVRIRKVTAKPAEKVTLAPTEPVRLMGGEAYLLRL
CCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCCHHHCCCHHHHHHH
LEGRPVIKGQKIRVEVFGHTLTFVITATRPSGVVVVTRNTAIELKEKPAEEVKRAVPDVT
HCCCCCCCCCEEEEEEECCEEEEEEEECCCCCEEEEECCCEEEECCCCHHHHHHHCCCCC
YEDIGGLKRELRLVREMIELPLKHPELFQRLGIEPPKGVLLYGPPGTGKTLIAKAVANEV
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHC
DAHFIPISGPEIMSKYYGESEQRLREIFEEAKENAPSIIFIDEIDSIAPKREEVTGEVER
CCEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHH
RVVAQLLALMDGLEARGDVIVIAATNRPDAIDPALRRPGRFDREIEIGVPDKEGRKEILE
HHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHCCCCCCCEEEECCCCCHHHHHHHH
IHTRKMPLAEDVDLEELAELTNGFVGADLEALCKEAAMHALRRVLPEIDIEAEEIPAEVI
HHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ENLKVTREDFMEALKNIEPSAMREVLVEVPNVKWEDIGGLEHAKQELMEAVEWPLKYPEV
HHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHCCCCCHHH
FRAANIKPPRGILLFGPPGTGKTLLAKAVANESNANFISVKGPELLSKWVGESEKHVREM
HHHCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHCCCCHHHHHHH
FRKARQVAPCVIFFDEIDSLAPRRGGIGDSHVTERVVSQLLTELDGLEELKDVVVIAATN
HHHHHHCCCEEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHCEEEEEECC
RPDMIDPALLRPGRLERHIYIPPPDKKARVEIFKIHLRGKPLADDVNIEELAEKTEGYSG
CCCCCCHHHCCCCCCCCEEECCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHCCCCC
ADIEAVCREAGMLAIRELIKPGMTREEAKEAAKKLKITKKHFEEALKKVRPSLTKEDVEK
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
YEKLIEDFHRMYA
HHHHHHHHHHHCC
>Mature Secondary Structure 
SDKKGEEITLRVAEAFYRDVGRGVARIDPAVMEKYGLQSGDIIEIIGKSTVPAIVWPSY
CCCCCCEEEHHHHHHHHHHHCCCHHHCCHHHHHHHCCCCCCEEEEECCCCCCEEECCCC
PEDRGTGIIRIDGSIRSNAGVGIDDKVRIRKVTAKPAEKVTLAPTEPVRLMGGEAYLLRL
CCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCCHHHCCCHHHHHHH
LEGRPVIKGQKIRVEVFGHTLTFVITATRPSGVVVVTRNTAIELKEKPAEEVKRAVPDVT
HCCCCCCCCCEEEEEEECCEEEEEEEECCCCCEEEEECCCEEEECCCCHHHHHHHCCCCC
YEDIGGLKRELRLVREMIELPLKHPELFQRLGIEPPKGVLLYGPPGTGKTLIAKAVANEV
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHC
DAHFIPISGPEIMSKYYGESEQRLREIFEEAKENAPSIIFIDEIDSIAPKREEVTGEVER
CCEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHH
RVVAQLLALMDGLEARGDVIVIAATNRPDAIDPALRRPGRFDREIEIGVPDKEGRKEILE
HHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHCCCCCCCEEEECCCCCHHHHHHHH
IHTRKMPLAEDVDLEELAELTNGFVGADLEALCKEAAMHALRRVLPEIDIEAEEIPAEVI
HHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ENLKVTREDFMEALKNIEPSAMREVLVEVPNVKWEDIGGLEHAKQELMEAVEWPLKYPEV
HHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHCCCCCHHH
FRAANIKPPRGILLFGPPGTGKTLLAKAVANESNANFISVKGPELLSKWVGESEKHVREM
HHHCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHCCCCHHHHHHH
FRKARQVAPCVIFFDEIDSLAPRRGGIGDSHVTERVVSQLLTELDGLEELKDVVVIAATN
HHHHHHCCCEEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHCEEEEEECC
RPDMIDPALLRPGRLERHIYIPPPDKKARVEIFKIHLRGKPLADDVNIEELAEKTEGYSG
CCCCCCHHHCCCCCCCCEEECCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHCCCCC
ADIEAVCREAGMLAIRELIKPGMTREEAKEAAKKLKITKKHFEEALKKVRPSLTKEDVEK
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
YEKLIEDFHRMYA
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9389475