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Identifier: 11498856

GI number: 11498856

Start: 1120755

End: 1121717

Strand: Reverse

Name: Not Available

Synonym: AF1257

Alternate gene names: NA

Gene position: 1121717-1120755 (Counterclockwise)

Preceding gene: 11498857

Following gene: 11498855

Centisome position: 51.49

GC content: 49.22

Gene sequence:

>963_bases
ATGAAGTTCCTCTTCTACCTCTCTGCGGATAACCTCGAAATCGCGAGAAAGGAGGTTCTTGTTCTTGCCGAACGCTACGG
ATGGGTTGAGGACTACCAGTTCGAGGAAAGACTTCTGCTGCTGGACTACGCAGGAGAGAAGTTTTTTGAGAGACTTGCCT
ACACAAACGAAGTAACCAAGATATACGACATCTGCTCAGTTAGCGAGCTTGAGCAGGTTTTTTCGGAGATTCCTGTTTAC
GACAGACTGTGCTGTGTCAGGGTTAAAGGAGGTAAGGGAAAAACGGCACTCGAAAGGAAGCTTGGAGCGTTGTTGTGGAA
GAGGGGAGCAAAAGTCAGCGTTTCGAATCCAGAAATCGTTTACAAAGTTTACATACAGGACGATAAATGCTACGTCGGTT
TGCTTGAGTTCGAAAGAGATACCAGACAGTTCTTCCTCAGGAGACCGGACAGAAGGCCCTTTTTAATGCCCTCCGCCATT
AAGCCAAAGCTTGCCAGGGCGCTGGTGAACCTTACGGGAGTTCTGGAAGGAGAAACTCTTCTCGACCCGATGTGCGGAAC
GGGCAGCTTTCTTATTGAGGCTGGCCTCATGGGAATCAATCCAATCGGAATCGACTTCATCGAGAAAATAGTCAGGGGCT
GCAGAGTAAACCTTGAGTACTACGGCATTGAAGGGAGCGTCCTGCTCGGTGACGCGAAAAACCTCCCCTTGAGGGACGAG
TCTGTCCGCGGGATAGCAACGGACTATCCGTACCTCAGGTCAACCAAGGCTGCGGGAACTCTTGATGAGCTCTACTCGAA
AACCAGCGAGGAATTTGAGAGGGTGCTAAAGAAGGGTGGAAGGGCCGCCATTGTCACCAACATTGATGTTGAGAGCTTTT
TTTCGAATTTCGAAATAGAGATGAAAACTGAAGAGAGAGTCCACGGAAGCCTGACGAGGAGAATATACCTGCTCAGAAGG
TAA

Upstream 100 bases:

>100_bases
GGGGCACCAAGACGAAGCTCATGATCGAGCTTGCGAGAAAAATTGCTGAGATAAGGGAGCAAAAGAGGGAGCAGAAGAAG
GACAAGAAAAAGAAGAAGAA

Downstream 100 bases:

>100_bases
CATTTATATTATTCAAAATGAAGGGAAAAGGGGGTAGCATGAAGCCAAGAGTAATGATTGTTGAGGACGACCTCGCAGTT
CTTGAGGCCCTTAAGTTAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKFLFYLSADNLEIARKEVLVLAERYGWVEDYQFEERLLLLDYAGEKFFERLAYTNEVTKIYDICSVSELEQVFSEIPVY
DRLCCVRVKGGKGKTALERKLGALLWKRGAKVSVSNPEIVYKVYIQDDKCYVGLLEFERDTRQFFLRRPDRRPFLMPSAI
KPKLARALVNLTGVLEGETLLDPMCGTGSFLIEAGLMGINPIGIDFIEKIVRGCRVNLEYYGIEGSVLLGDAKNLPLRDE
SVRGIATDYPYLRSTKAAGTLDELYSKTSEEFERVLKKGGRAAIVTNIDVESFFSNFEIEMKTEERVHGSLTRRIYLLRR

Sequences:

>Translated_320_residues
MKFLFYLSADNLEIARKEVLVLAERYGWVEDYQFEERLLLLDYAGEKFFERLAYTNEVTKIYDICSVSELEQVFSEIPVY
DRLCCVRVKGGKGKTALERKLGALLWKRGAKVSVSNPEIVYKVYIQDDKCYVGLLEFERDTRQFFLRRPDRRPFLMPSAI
KPKLARALVNLTGVLEGETLLDPMCGTGSFLIEAGLMGINPIGIDFIEKIVRGCRVNLEYYGIEGSVLLGDAKNLPLRDE
SVRGIATDYPYLRSTKAAGTLDELYSKTSEEFERVLKKGGRAAIVTNIDVESFFSNFEIEMKTEERVHGSLTRRIYLLRR
>Mature_320_residues
MKFLFYLSADNLEIARKEVLVLAERYGWVEDYQFEERLLLLDYAGEKFFERLAYTNEVTKIYDICSVSELEQVFSEIPVY
DRLCCVRVKGGKGKTALERKLGALLWKRGAKVSVSNPEIVYKVYIQDDKCYVGLLEFERDTRQFFLRRPDRRPFLMPSAI
KPKLARALVNLTGVLEGETLLDPMCGTGSFLIEAGLMGINPIGIDFIEKIVRGCRVNLEYYGIEGSVLLGDAKNLPLRDE
SVRGIATDYPYLRSTKAAGTLDELYSKTSEEFERVLKKGGRAAIVTNIDVESFFSNFEIEMKTEERVHGSLTRRIYLLRR

Specific function: Unknown

COG id: COG1041

COG function: function code L; Predicted DNA modification methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 THUMP domain

Homologues:

Organism=Homo sapiens, GI254553431, Length=266, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32566195, Length=149, Percent_Identity=31.5436241610738, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1257_ARCFU (O29011)

Other databases:

- EMBL:   AE000782
- PIR:   H69406
- RefSeq:   NP_070085.1
- ProteinModelPortal:   O29011
- SMR:   O29011
- GeneID:   1484481
- GenomeReviews:   AE000782_GR
- KEGG:   afu:AF1257
- NMPDR:   fig|224325.1.peg.1245
- TIGR:   AF_1257
- HOGENOM:   HBG724197
- OMA:   GSDIDEQ
- ProtClustDB:   CLSK2746824
- BioCyc:   AFUL224325:AF_1257-MONOMER
- InterPro:   IPR005885
- InterPro:   IPR000241
- InterPro:   IPR004114
- SMART:   SM00981
- TIGRFAMs:   TIGR01177

Pfam domain/function: PF02926 THUMP; PF01170 UPF0020

EC number: NA

Molecular weight: Translated: 36674; Mature: 36674

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS51165 THUMP; PS01261 UPF0020

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLFYLSADNLEIARKEVLVLAERYGWVEDYQFEERLLLLDYAGEKFFERLAYTNEVTK
CEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
IYDICSVSELEQVFSEIPVYDRLCCVRVKGGKGKTALERKLGALLWKRGAKVSVSNPEIV
HHHHHCHHHHHHHHHHCCHHHCEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEECCCCEE
YKVYIQDDKCYVGLLEFERDTRQFFLRRPDRRPFLMPSAIKPKLARALVNLTGVLEGETL
EEEEEECCCEEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHEECCCHH
LDPMCGTGSFLIEAGLMGINPIGIDFIEKIVRGCRVNLEYYGIEGSVLLGDAKNLPLRDE
HCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHEEEEEEEECCCEEEEECCCCCCCCCC
SVRGIATDYPYLRSTKAAGTLDELYSKTSEEFERVLKKGGRAAIVTNIDVESFFSNFEIE
CCCCEECCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCEEE
MKTEERVHGSLTRRIYLLRR
EEHHHHHHHHHHHEEEEECC
>Mature Secondary Structure
MKFLFYLSADNLEIARKEVLVLAERYGWVEDYQFEERLLLLDYAGEKFFERLAYTNEVTK
CEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
IYDICSVSELEQVFSEIPVYDRLCCVRVKGGKGKTALERKLGALLWKRGAKVSVSNPEIV
HHHHHCHHHHHHHHHHCCHHHCEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEECCCCEE
YKVYIQDDKCYVGLLEFERDTRQFFLRRPDRRPFLMPSAIKPKLARALVNLTGVLEGETL
EEEEEECCCEEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHEECCCHH
LDPMCGTGSFLIEAGLMGINPIGIDFIEKIVRGCRVNLEYYGIEGSVLLGDAKNLPLRDE
HCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHEEEEEEEECCCEEEEECCCCCCCCCC
SVRGIATDYPYLRSTKAAGTLDELYSKTSEEFERVLKKGGRAAIVTNIDVESFFSNFEIE
CCCCEECCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCEEE
MKTEERVHGSLTRRIYLLRR
EEHHHHHHHHHHHEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475