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The map label for this gene is panF-2

Identifier: 11498804

GI number: 11498804

Start: 1075937

End: 1077361

Strand: Reverse

Name: panF-2

Synonym: AF1205

Alternate gene names: 11498804

Gene position: 1077361-1075937 (Counterclockwise)

Preceding gene: 11498805

Following gene: 11498803

Centisome position: 49.46

GC content: 52.63

Gene sequence:

>1425_bases
GTGTATTTCCTGGTGACAACCCTTGGTGTTGGATTCTACCTGATGAAAAGGATGGAAAAATCCGAAGAGGACTATCTGGT
TGCGAAAAGGGGTCTGGGTGCGGTTCCAGTTGGTGTTACCCTCGCCCTTACGGTGCTTGGAACTCCCCACATACTGGGAG
TTATGGAGTCGGCATATGACATCGGATTGCCCGCGGTCTGGTTTTCCTTCGCACACGCAATAATGCTGGCAATTGTATGT
CTTTTTACTGGAAGATGGGCGAGAAAGCTCAAAGTGGAGTCCGTTCCAGAGTTTCTTGACGTCATTTTCAGCAACTACTG
GTTGAGGCTGATGGTCGGTGCTGTCATAGCCGGAGCCATTTTCGGAATCTGCACCCTTGAAACACAGGGACTCGGTGTTT
TCGTCTCAATTCTCACCGGAACTTCTATAGAAGTGGGGATAGTGATTGGAGCGCTGATAGGAATTCTTTACGTCGTCCTT
TCGGGCATGAAAGAGGTTGCATGGCTCAACGTTCTCAACGCGGTTATTCTTTACATAGGCATCATTGCCGCAACCTTCGT
TCTCGGCTCAGGGCTGCAGAACGGATGGGAGGGCGTTAACGAGTTCTACATCTCCAACGATTTGGCGGGCAAACTCAACA
TATTCGGATCATGGGAGGTTTTCGTCGGCTTTGCTCTCGTGAACGTGCTCGCAACGGTGTTTTTCCAGGGAATCAGCCAG
CAGGGACTGCATGCGGCACTGGCAGCAAAATCTCCGGATGTGCTTAGAAAAGCTATGCTCATTGCCGTGCCTGTGAACGG
ATCCTTTGCCGTGTTTGCCGCAGTTATGGGAATGGCTGCAAGGGCAACACCGGAATTTGCCGAGCTCGGTGCGAAGACTG
CTACACCCGCAATGATTGTGTCGGTTCTGCCAACATGGGCGTCGGCACTGCTTCTTGCAACCTGTCTTGTTGCTGTGCTG
TCATCCTACGCCATCACACTTCTCGCCCCCACAACGATATTCGTTAACGACATTTACAAGGCCGTTCTCAAGCCGAATGC
CTCGCATGAGGAGCTTCTCCGGCTCTCCAGAATTCTTACCGTTCTGCTCGCTGTTGCCGCGCTGATTCCTGCTGTGAGCC
TCCCACCAATACTCGCCGCCATGATGTGGTTGTTCTCATGGCTCGTCCCAGTGTTCTGGTTCGTCATATTCGGGCTCTTC
TGGAAGAGGTCCGCCCCAGCGGCGATTATCACGTGCTTGCTGGTTTGGGTGACCATAAACGCATGGACGATGACTCCACT
GCCAGAAGTTCTCGGAGCTCCGGGTTGGCTGCATCAGGTCTATCTCGCTCTCATAGTTACTCTGGTGATCGGCTCACTGC
TAAACGCGGTTCTGCCAGGGAAGCCGGGACTCTTCAGAGAAAAAGCTTTGGCTGTGAGGGGGTGA

Upstream 100 bases:

>100_bases
ATGATCAGCTGGCGAAGATTCTCAAATTGATTTTGGAGGATGGTTAATTGCAGGAGGTGGTATTTTGGAGGCAAGATGGG
ATATACTGATACCCGTTTTG

Downstream 100 bases:

>100_bases
AAGGGAATGTTTCCGGCAGACGTTATACTGCAATGCTTCGGATTCAGTGTGGGAATAGCTCTGGTGGGATACGTCATCTC
GCTATTCCTTGACTGGAGCG

Product: pantothenate permease (panF-2)

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MYFLVTTLGVGFYLMKRMEKSEEDYLVAKRGLGAVPVGVTLALTVLGTPHILGVMESAYDIGLPAVWFSFAHAIMLAIVC
LFTGRWARKLKVESVPEFLDVIFSNYWLRLMVGAVIAGAIFGICTLETQGLGVFVSILTGTSIEVGIVIGALIGILYVVL
SGMKEVAWLNVLNAVILYIGIIAATFVLGSGLQNGWEGVNEFYISNDLAGKLNIFGSWEVFVGFALVNVLATVFFQGISQ
QGLHAALAAKSPDVLRKAMLIAVPVNGSFAVFAAVMGMAARATPEFAELGAKTATPAMIVSVLPTWASALLLATCLVAVL
SSYAITLLAPTTIFVNDIYKAVLKPNASHEELLRLSRILTVLLAVAALIPAVSLPPILAAMMWLFSWLVPVFWFVIFGLF
WKRSAPAAIITCLLVWVTINAWTMTPLPEVLGAPGWLHQVYLALIVTLVIGSLLNAVLPGKPGLFREKALAVRG

Sequences:

>Translated_474_residues
MYFLVTTLGVGFYLMKRMEKSEEDYLVAKRGLGAVPVGVTLALTVLGTPHILGVMESAYDIGLPAVWFSFAHAIMLAIVC
LFTGRWARKLKVESVPEFLDVIFSNYWLRLMVGAVIAGAIFGICTLETQGLGVFVSILTGTSIEVGIVIGALIGILYVVL
SGMKEVAWLNVLNAVILYIGIIAATFVLGSGLQNGWEGVNEFYISNDLAGKLNIFGSWEVFVGFALVNVLATVFFQGISQ
QGLHAALAAKSPDVLRKAMLIAVPVNGSFAVFAAVMGMAARATPEFAELGAKTATPAMIVSVLPTWASALLLATCLVAVL
SSYAITLLAPTTIFVNDIYKAVLKPNASHEELLRLSRILTVLLAVAALIPAVSLPPILAAMMWLFSWLVPVFWFVIFGLF
WKRSAPAAIITCLLVWVTINAWTMTPLPEVLGAPGWLHQVYLALIVTLVIGSLLNAVLPGKPGLFREKALAVRG
>Mature_474_residues
MYFLVTTLGVGFYLMKRMEKSEEDYLVAKRGLGAVPVGVTLALTVLGTPHILGVMESAYDIGLPAVWFSFAHAIMLAIVC
LFTGRWARKLKVESVPEFLDVIFSNYWLRLMVGAVIAGAIFGICTLETQGLGVFVSILTGTSIEVGIVIGALIGILYVVL
SGMKEVAWLNVLNAVILYIGIIAATFVLGSGLQNGWEGVNEFYISNDLAGKLNIFGSWEVFVGFALVNVLATVFFQGISQ
QGLHAALAAKSPDVLRKAMLIAVPVNGSFAVFAAVMGMAARATPEFAELGAKTATPAMIVSVLPTWASALLLATCLVAVL
SSYAITLLAPTTIFVNDIYKAVLKPNASHEELLRLSRILTVLLAVAALIPAVSLPPILAAMMWLFSWLVPVFWFVIFGLF
WKRSAPAAIITCLLVWVTINAWTMTPLPEVLGAPGWLHQVYLALIVTLVIGSLLNAVLPGKPGLFREKALAVRG

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Escherichia coli, GI1790113, Length=440, Percent_Identity=24.0909090909091, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082237, Length=446, Percent_Identity=21.9730941704036, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17539284, Length=411, Percent_Identity=22.3844282238443, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 50856; Mature: 50856

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCC
>Mature Secondary Structure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CEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]