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The map label for this gene is tlpC-2

Identifier: 11498650

GI number: 11498650

Start: 950947

End: 953451

Strand: Reverse

Name: tlpC-2

Synonym: AF1045

Alternate gene names: 11498650

Gene position: 953451-950947 (Counterclockwise)

Preceding gene: 11498651

Following gene: 11498649

Centisome position: 43.77

GC content: 49.26

Gene sequence:

>2505_bases
ATGAATGACGAGCTTGCAAACCTGATTTCAGCCTTGGGGGATGAGGAGGCTGTATCGAGGCTGAAATCTCTGCTGGAGGG
ATCGAAGAAGCCCCCAGATTCAGATTGCAAGGAGGAGAGGGAGGAGATTGAGGAACTGCGACGAAAACTTGCTGAAACGG
AAAGAGAGCTGGAGAAAACCAAAAAGTTCGTCAGAGAACTGGTAAGGCAGATTCCGAAGCCCGCCTTCGTCCTTTTCCTT
AACAAGGACGGCATTATAGAGTACATCAATGAATACGCAGCGGAGGTTTACGGTGCGGAGATCTCAGAGATGATTGGCAG
GAAACCTTCAGAACTTGCGAGCAACGTTGCCGCTGGAGGAAAGACATTTGTAGAGCTGGCATTCGAAAACAAAATGAAAA
TTGAGGGGAAAGAGGGGTTCCTGGAGGTCAAAACCGGAAAAGCGATGCCCATCCTTACATCATGCGCCCCTGTGTACGTC
GATGGAGAGTTTGAGGGAATGGTGGACTTCTTCATAGACATTACAGAGCAGAAAAAGAGAGAGGAGGAGGCGAAGAAGGC
CTACGAGCTCATAAAAGAGGTTTTCAGAAACCTGCCGACGTACGTTATATTCGTAGGGGAGGATGGGTTGATAAAGTTCG
CAAACAACAACGTAGCGAGGTTAGCGGGCTTCGAGACTGCTGATGAGGTTGTGGGGTTAAGGCCAGCGGATGTTGCAGTA
ATACACAAAGACTACCTCGACAACGCCAAGAAAATAGTGGAAGCGATAAAGAACAGGGAGAGGATTGAAAACGTCGAGGT
TAAGCTCGTAGGGAAAGATGGTAGCGAGTTCATAGCTTCTGCTTCAATATATCCAGTATACGTCGGAGACGAATTTGCGG
GGTACATTGAGGTCTTTTACGATATCACAGAGCTTAAGGAGAAGGAGGCGGAAATGAAGGGACTGGTCAACAGCACTCCT
GTTGCGGTAATGTACATCGACTCCAATCACAACGTTGTTTACTGGAACAATGCGGCAGAAGAGCTTACAGGAGTTAAGGC
TGAGGAGATGGTGGGGACGAAGAGAACATGGTATCCGTTCTACGATCAGGAGAGGCCAATACTGGCTGATCTGGTTCTCG
ACAACCCACATGAGGCGCACAAGCTTTACGACGTTATTAAGAAACATCCTGTAATTGAAGGAGCGTATCTGACCGAGATA
TGGCTCAACTTCCCGAGAAATGGCAGAAAGGCTTACGTCAGGGCTACAGCCGCACCGGTTTACAATGAGAAGGGGGAGAT
TATTGGTGTGGTAGAGTCTATTGAGGACCTCACCGAAATCAAGGAGAAAGAAAAAGAAATCGAAGAAATGCTCGCCTACA
CCGGCAGATGCCTCAACATGCTCAGCAACGGAATCAGAGAGCTGCAGGCAGGAAACCTCGACGTCAGGCTTGAAAAAATC
AGGGACGACGAGTTCGGAGAGACGTTCGAGGCTTTCAACGAGTTCGCAGGAAGGATGCAGGAAATTGTAAGGAAGCTTGC
CGATGACATGAAGGAAACTGCCAACCAAGTTAGAGAAGCTGCAGAAGCAGTAAACCAGATGAACGCTGGAATGCAGCAGA
TAAGCTCAGCCTCGCAGCAAATAGCAACGGGAAGCGAGAACCTATCAAGGCTGGCAAACGCCTCAACACTCGACCTCAAG
GCAGCAGAAGAAATATTCAAGGACCTGACCGCAAGAGCCGAAAACTCCGCCAAATTCGCCGATGAGGCATCGCAGAATGC
AGAGATGGCGAAGAAAGAAGGTGTTAAAGCTCTAGAAATCATCAAGAGCATAGTCCAGGAGGTAGAGAACGCATCAAAAG
TCGTCGAAACCCTTGAGCAGGCGGTAAGAAACATAGGCAAGGTAACTGAAAGAATAAAATCAATAGCAGATCAAACAAAC
CTCCTCGCCCTCAATGCAGCTATCGAAGCGGCAAGAGCTGGAGAGCACGGAAGAGGCTTTGCTGTTGTTGCTGATGAGGT
TAGAAAGCTCGCTGAAGAGTCGAGAAAGAGCACTGAGGAGATAGACGAGATAGTCAGGAACGTGCAGGAAGAAACGAGAA
AGGTAATCGAGGCAACGAACAAGGTTAAGGAGAGCAGCCTGCAGGGGAGCGAGGGGATAGAAAACGCCCTCATGAAGGCA
GGAGAAATAGCTGAAGCTGTTAACAGAATCAACGAAATGCTCGGGCAGGTTGCGGCAAAGGCAGAAGAAGGCCTCGCAAA
GATAGAGCAGCTCGCCAGAAACTTCGAGGAGGTGGCATCAACAGCAGAAGAAAACGCAGCGAGCAGCGAGGAAACCTCAG
CAGCAATTGAAGAGCAGACAGCAGCAGTCCAGCAGGTCAGCATCGCAATGGAGAAAGTCAACGAGATAGCCAACGCAACC
CTGCAAACCATAATCGAGAACTTCAGAATCTTCGACGCTCTCGGCCAGGACATCTCCGCCAGCTATGCAAAGACGATGAC
GAATGGAGGGGACAAACTCCTCTAA

Upstream 100 bases:

>100_bases
TTTCCAAACGCTAATTACACTTCTGAATTTTCTTATTCGAAATTTTACTTTATAGAGAAAATTTTATTTTTTATTTTCGC
AATCTACTTTCGGTGGTGTT

Downstream 100 bases:

>100_bases
TTTTTTGGAGGTGATGTTAGTGCAGCAGTCGGAAGGTGTGATTAAGGGTAGCGAGACTGTTCAGGTTATCGTGTTCAACC
TCGGCGATGAGAGGTACGGC

Product: methyl-accepting chemotaxis protein (tlpC-2)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 834; Mature: 834

Protein sequence:

>834_residues
MNDELANLISALGDEEAVSRLKSLLEGSKKPPDSDCKEEREEIEELRRKLAETERELEKTKKFVRELVRQIPKPAFVLFL
NKDGIIEYINEYAAEVYGAEISEMIGRKPSELASNVAAGGKTFVELAFENKMKIEGKEGFLEVKTGKAMPILTSCAPVYV
DGEFEGMVDFFIDITEQKKREEEAKKAYELIKEVFRNLPTYVIFVGEDGLIKFANNNVARLAGFETADEVVGLRPADVAV
IHKDYLDNAKKIVEAIKNRERIENVEVKLVGKDGSEFIASASIYPVYVGDEFAGYIEVFYDITELKEKEAEMKGLVNSTP
VAVMYIDSNHNVVYWNNAAEELTGVKAEEMVGTKRTWYPFYDQERPILADLVLDNPHEAHKLYDVIKKHPVIEGAYLTEI
WLNFPRNGRKAYVRATAAPVYNEKGEIIGVVESIEDLTEIKEKEKEIEEMLAYTGRCLNMLSNGIRELQAGNLDVRLEKI
RDDEFGETFEAFNEFAGRMQEIVRKLADDMKETANQVREAAEAVNQMNAGMQQISSASQQIATGSENLSRLANASTLDLK
AAEEIFKDLTARAENSAKFADEASQNAEMAKKEGVKALEIIKSIVQEVENASKVVETLEQAVRNIGKVTERIKSIADQTN
LLALNAAIEAARAGEHGRGFAVVADEVRKLAEESRKSTEEIDEIVRNVQEETRKVIEATNKVKESSLQGSEGIENALMKA
GEIAEAVNRINEMLGQVAAKAEEGLAKIEQLARNFEEVASTAEENAASSEETSAAIEEQTAAVQQVSIAMEKVNEIANAT
LQTIIENFRIFDALGQDISASYAKTMTNGGDKLL

Sequences:

>Translated_834_residues
MNDELANLISALGDEEAVSRLKSLLEGSKKPPDSDCKEEREEIEELRRKLAETERELEKTKKFVRELVRQIPKPAFVLFL
NKDGIIEYINEYAAEVYGAEISEMIGRKPSELASNVAAGGKTFVELAFENKMKIEGKEGFLEVKTGKAMPILTSCAPVYV
DGEFEGMVDFFIDITEQKKREEEAKKAYELIKEVFRNLPTYVIFVGEDGLIKFANNNVARLAGFETADEVVGLRPADVAV
IHKDYLDNAKKIVEAIKNRERIENVEVKLVGKDGSEFIASASIYPVYVGDEFAGYIEVFYDITELKEKEAEMKGLVNSTP
VAVMYIDSNHNVVYWNNAAEELTGVKAEEMVGTKRTWYPFYDQERPILADLVLDNPHEAHKLYDVIKKHPVIEGAYLTEI
WLNFPRNGRKAYVRATAAPVYNEKGEIIGVVESIEDLTEIKEKEKEIEEMLAYTGRCLNMLSNGIRELQAGNLDVRLEKI
RDDEFGETFEAFNEFAGRMQEIVRKLADDMKETANQVREAAEAVNQMNAGMQQISSASQQIATGSENLSRLANASTLDLK
AAEEIFKDLTARAENSAKFADEASQNAEMAKKEGVKALEIIKSIVQEVENASKVVETLEQAVRNIGKVTERIKSIADQTN
LLALNAAIEAARAGEHGRGFAVVADEVRKLAEESRKSTEEIDEIVRNVQEETRKVIEATNKVKESSLQGSEGIENALMKA
GEIAEAVNRINEMLGQVAAKAEEGLAKIEQLARNFEEVASTAEENAASSEETSAAIEEQTAAVQQVSIAMEKVNEIANAT
LQTIIENFRIFDALGQDISASYAKTMTNGGDKLL
>Mature_834_residues
MNDELANLISALGDEEAVSRLKSLLEGSKKPPDSDCKEEREEIEELRRKLAETERELEKTKKFVRELVRQIPKPAFVLFL
NKDGIIEYINEYAAEVYGAEISEMIGRKPSELASNVAAGGKTFVELAFENKMKIEGKEGFLEVKTGKAMPILTSCAPVYV
DGEFEGMVDFFIDITEQKKREEEAKKAYELIKEVFRNLPTYVIFVGEDGLIKFANNNVARLAGFETADEVVGLRPADVAV
IHKDYLDNAKKIVEAIKNRERIENVEVKLVGKDGSEFIASASIYPVYVGDEFAGYIEVFYDITELKEKEAEMKGLVNSTP
VAVMYIDSNHNVVYWNNAAEELTGVKAEEMVGTKRTWYPFYDQERPILADLVLDNPHEAHKLYDVIKKHPVIEGAYLTEI
WLNFPRNGRKAYVRATAAPVYNEKGEIIGVVESIEDLTEIKEKEKEIEEMLAYTGRCLNMLSNGIRELQAGNLDVRLEKI
RDDEFGETFEAFNEFAGRMQEIVRKLADDMKETANQVREAAEAVNQMNAGMQQISSASQQIATGSENLSRLANASTLDLK
AAEEIFKDLTARAENSAKFADEASQNAEMAKKEGVKALEIIKSIVQEVENASKVVETLEQAVRNIGKVTERIKSIADQTN
LLALNAAIEAARAGEHGRGFAVVADEVRKLAEESRKSTEEIDEIVRNVQEETRKVIEATNKVKESSLQGSEGIENALMKA
GEIAEAVNRINEMLGQVAAKAEEGLAKIEQLARNFEEVASTAEENAASSEETSAAIEEQTAAVQQVSIAMEKVNEIANAT
LQTIIENFRIFDALGQDISASYAKTMTNGGDKLL

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=278, Percent_Identity=30.9352517985612, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI2367378, Length=308, Percent_Identity=30.8441558441558, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1788195, Length=306, Percent_Identity=30.718954248366, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1787690, Length=322, Percent_Identity=31.055900621118, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1789453, Length=294, Percent_Identity=29.5918367346939, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 92718; Mature: 92718

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS00216 SUGAR_TRANSPORT_1 ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDELANLISALGDEEAVSRLKSLLEGSKKPPDSDCKEEREEIEELRRKLAETERELEKT
CCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KKFVRELVRQIPKPAFVLFLNKDGIIEYINEYAAEVYGAEISEMIGRKPSELASNVAAGG
HHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
KTFVELAFENKMKIEGKEGFLEVKTGKAMPILTSCAPVYVDGEFEGMVDFFIDITEQKKR
HHHHHEEECCCEEECCCCCEEEEECCCCCCCHHCCCCEEECCCHHHHHHHHHHHHHHHHH
EEEAKKAYELIKEVFRNLPTYVIFVGEDGLIKFANNNVARLAGFETADEVVGLRPADVAV
HHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCHHHCCCCCHHHHHCCCCCHHHH
IHKDYLDNAKKIVEAIKNRERIENVEVKLVGKDGSEFIASASIYPVYVGDEFAGYIEVFY
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHCCCEEEEEECCHHHHHHHHHH
DITELKEKEAEMKGLVNSTPVAVMYIDSNHNVVYWNNAAEELTGVKAEEMVGTKRTWYPF
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCHHHHHCCCHHHHHCCCCCCCCC
YDQERPILADLVLDNPHEAHKLYDVIKKHPVIEGAYLTEIWLNFPRNGRKAYVRATAAPV
CCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCC
YNEKGEIIGVVESIEDLTEIKEKEKEIEEMLAYTGRCLNMLSNGIRELQAGNLDVRLEKI
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHH
RDDEFGETFEAFNEFAGRMQEIVRKLADDMKETANQVREAAEAVNQMNAGMQQISSASQQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IATGSENLSRLANASTLDLKAAEEIFKDLTARAENSAKFADEASQNAEMAKKEGVKALEI
HHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHH
IKSIVQEVENASKVVETLEQAVRNIGKVTERIKSIADQTNLLALNAAIEAARAGEHGRGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AVVADEVRKLAEESRKSTEEIDEIVRNVQEETRKVIEATNKVKESSLQGSEGIENALMKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GEIAEAVNRINEMLGQVAAKAEEGLAKIEQLARNFEEVASTAEENAASSEETSAAIEEQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AAVQQVSIAMEKVNEIANATLQTIIENFRIFDALGQDISASYAKTMTNGGDKLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNDELANLISALGDEEAVSRLKSLLEGSKKPPDSDCKEEREEIEELRRKLAETERELEKT
CCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KKFVRELVRQIPKPAFVLFLNKDGIIEYINEYAAEVYGAEISEMIGRKPSELASNVAAGG
HHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
KTFVELAFENKMKIEGKEGFLEVKTGKAMPILTSCAPVYVDGEFEGMVDFFIDITEQKKR
HHHHHEEECCCEEECCCCCEEEEECCCCCCCHHCCCCEEECCCHHHHHHHHHHHHHHHHH
EEEAKKAYELIKEVFRNLPTYVIFVGEDGLIKFANNNVARLAGFETADEVVGLRPADVAV
HHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCHHHCCCCCHHHHHCCCCCHHHH
IHKDYLDNAKKIVEAIKNRERIENVEVKLVGKDGSEFIASASIYPVYVGDEFAGYIEVFY
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHCCCEEEEEECCHHHHHHHHHH
DITELKEKEAEMKGLVNSTPVAVMYIDSNHNVVYWNNAAEELTGVKAEEMVGTKRTWYPF
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCHHHHHCCCHHHHHCCCCCCCCC
YDQERPILADLVLDNPHEAHKLYDVIKKHPVIEGAYLTEIWLNFPRNGRKAYVRATAAPV
CCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCC
YNEKGEIIGVVESIEDLTEIKEKEKEIEEMLAYTGRCLNMLSNGIRELQAGNLDVRLEKI
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHH
RDDEFGETFEAFNEFAGRMQEIVRKLADDMKETANQVREAAEAVNQMNAGMQQISSASQQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IATGSENLSRLANASTLDLKAAEEIFKDLTARAENSAKFADEASQNAEMAKKEGVKALEI
HHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHH
IKSIVQEVENASKVVETLEQAVRNIGKVTERIKSIADQTNLLALNAAIEAARAGEHGRGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AVVADEVRKLAEESRKSTEEIDEIVRNVQEETRKVIEATNKVKESSLQGSEGIENALMKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GEIAEAVNRINEMLGQVAAKAEEGLAKIEQLARNFEEVASTAEENAASSEETSAAIEEQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AAVQQVSIAMEKVNEIANATLQTIIENFRIFDALGQDISASYAKTMTNGGDKLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]