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The map label for this gene is caiB-2

Identifier: 11498595

GI number: 11498595

Start: 891233

End: 892204

Strand: Reverse

Name: caiB-2

Synonym: AF0990

Alternate gene names: 11498595

Gene position: 892204-891233 (Counterclockwise)

Preceding gene: 11498596

Following gene: 11498592

Centisome position: 40.96

GC content: 50.51

Gene sequence:

>972_bases
ATGACGCTCGATTTGAAACAGGAGAAGGGCAGGGAGATTTTTTTCAGGCTTGCAGAGAAGGCTGATGTCATAATCGAGAA
CTTTGTTCCGGGAGTTGTGAAGAAGCTCGGTGTTGACTATGAGGCTGTAAAAAAAGTAAAGCCGGACATCATCTATTGCC
ACGTTTCGGGCTTTGGGCAGGACGGGCCTTACAGAGACCGCCCGGCCTTTGACCAGCTCATTCAGGGCGAGGCGGGGATA
ATCAGCTACACAGGAACAAGAGAAACGCCGTGCAAGATTAACGTTCCCATCACTGATTTGCTGGCTTCAATGTACGGTGC
CTATGCTGTTCTCGCAGCACTGCTGAGAAGAGAAAAGACGGGGGAGGGAATGGAGATTGACATCTCCCTGTTTGATTGTG
CCGTCACAATGATGCTCAATCTGATGAACATGGCCATTGTCGAGGGAATGAAGGATGAAGAGCTTAGAATGGGGACAAAG
TACTTCCTCGCCACACCCTACGAGCCTTATCCGGCTGGAGACGGAAAGCTGGTCAACGTTGTTGTTGCAACCGAGTGGCA
CTGGAAGGAGTTCTGCAAGGCTGTGGGGCTGGAGGAGCTGCTTGACGACCCAAGGTTTGCAACAAACCAGCAGAGGCTGA
AGCACAGGGAGCAGCTTGAGAGAATCATCATAGAGAAGTTCAGGGAGAAGCCGAGGGACGACTGGATAGAGATACTGCTC
AAAGCTGGAGTGCCATGCGGGGCTGTGAACACAATACAGGAAGTTATAGAGCACCCGCAGACAAAGCACCGCAAAACTGT
GGTTGAGGTGGATTACCCTGAACTTGGAAAAATCAAGCTCTTCAACAACCCTGTGAAGTTCTCAGGCTTTGAGGTTGAGG
TGAGAAGGCCGCCAAAGCTTGGGGAGCACACTGAAGAGATTTTGAAGTCTATTGGGCTTTCAGAGGAGGAAATAGCAGAT
TTGAGGGCTTAA

Upstream 100 bases:

>100_bases
CATTGAAAGGCCGGGAGTTGGGGATCTGGCTAGGCACTGGATCCCCATAAGGGCTGACCTGAGCTTTTACTTTGGTGTTG
TCAACAGAAACAAAAAGTCA

Downstream 100 bases:

>100_bases
AAGTAATTTAAAATATTTTTATTCCTCCATCATGGATATTTTCTTGGTCTGTCTGAAACCCAGGAAAACCACAACAACAG
AAATCAGTGCAAGCATTGGA

Product: L-carnitine dehydratase (caiB-2)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MTLDLKQEKGREIFFRLAEKADVIIENFVPGVVKKLGVDYEAVKKVKPDIIYCHVSGFGQDGPYRDRPAFDQLIQGEAGI
ISYTGTRETPCKINVPITDLLASMYGAYAVLAALLRREKTGEGMEIDISLFDCAVTMMLNLMNMAIVEGMKDEELRMGTK
YFLATPYEPYPAGDGKLVNVVVATEWHWKEFCKAVGLEELLDDPRFATNQQRLKHREQLERIIIEKFREKPRDDWIEILL
KAGVPCGAVNTIQEVIEHPQTKHRKTVVEVDYPELGKIKLFNNPVKFSGFEVEVRRPPKLGEHTEEILKSIGLSEEEIAD
LRA

Sequences:

>Translated_323_residues
MTLDLKQEKGREIFFRLAEKADVIIENFVPGVVKKLGVDYEAVKKVKPDIIYCHVSGFGQDGPYRDRPAFDQLIQGEAGI
ISYTGTRETPCKINVPITDLLASMYGAYAVLAALLRREKTGEGMEIDISLFDCAVTMMLNLMNMAIVEGMKDEELRMGTK
YFLATPYEPYPAGDGKLVNVVVATEWHWKEFCKAVGLEELLDDPRFATNQQRLKHREQLERIIIEKFREKPRDDWIEILL
KAGVPCGAVNTIQEVIEHPQTKHRKTVVEVDYPELGKIKLFNNPVKFSGFEVEVRRPPKLGEHTEEILKSIGLSEEEIAD
LRA
>Mature_322_residues
TLDLKQEKGREIFFRLAEKADVIIENFVPGVVKKLGVDYEAVKKVKPDIIYCHVSGFGQDGPYRDRPAFDQLIQGEAGII
SYTGTRETPCKINVPITDLLASMYGAYAVLAALLRREKTGEGMEIDISLFDCAVTMMLNLMNMAIVEGMKDEELRMGTKY
FLATPYEPYPAGDGKLVNVVVATEWHWKEFCKAVGLEELLDDPRFATNQQRLKHREQLERIIIEKFREKPRDDWIEILLK
AGVPCGAVNTIQEVIEHPQTKHRKTVVEVDYPELGKIKLFNNPVKFSGFEVEVRRPPKLGEHTEEILKSIGLSEEEIADL
RA

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=313, Percent_Identity=32.9073482428115, Blast_Score=202, Evalue=3e-52,
Organism=Homo sapiens, GI300863124, Length=339, Percent_Identity=30.3834808259587, Blast_Score=189, Evalue=2e-48,
Organism=Homo sapiens, GI300863126, Length=312, Percent_Identity=28.525641025641, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI13376042, Length=306, Percent_Identity=29.7385620915033, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI266456254, Length=335, Percent_Identity=28.0597014925373, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI42794625, Length=335, Percent_Identity=28.0597014925373, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI266458393, Length=205, Percent_Identity=27.3170731707317, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI266458397, Length=189, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI87082093, Length=310, Percent_Identity=30.3225806451613, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1788717, Length=350, Percent_Identity=27.4285714285714, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1786222, Length=333, Percent_Identity=26.4264264264264, Blast_Score=86, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24648431, Length=325, Percent_Identity=32.9230769230769, Blast_Score=192, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24585488, Length=273, Percent_Identity=28.2051282051282, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 36713; Mature: 36582

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDLKQEKGREIFFRLAEKADVIIENFVPGVVKKLGVDYEAVKKVKPDIIYCHVSGFGQ
CCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEECCCCC
DGPYRDRPAFDQLIQGEAGIISYTGTRETPCKINVPITDLLASMYGAYAVLAALLRREKT
CCCCCCCHHHHHHHCCCCCEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCC
GEGMEIDISLFDCAVTMMLNLMNMAIVEGMKDEELRMGTKYFLATPYEPYPAGDGKLVNV
CCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCEEEEECCCCCCCCCCCCEEEE
VVATEWHWKEFCKAVGLEELLDDPRFATNQQRLKHREQLERIIIEKFREKPRDDWIEILL
EEECCHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KAGVPCGAVNTIQEVIEHPQTKHRKTVVEVDYPELGKIKLFNNPVKFSGFEVEVRRPPKL
HCCCCCCHHHHHHHHHHCCCHHHCCEEEEECCCCCCEEEEECCCCEECCEEEEECCCCCC
GEHTEEILKSIGLSEEEIADLRA
CHHHHHHHHHCCCCHHHHHHCCC
>Mature Secondary Structure 
TLDLKQEKGREIFFRLAEKADVIIENFVPGVVKKLGVDYEAVKKVKPDIIYCHVSGFGQ
CCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEECCCCC
DGPYRDRPAFDQLIQGEAGIISYTGTRETPCKINVPITDLLASMYGAYAVLAALLRREKT
CCCCCCCHHHHHHHCCCCCEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCC
GEGMEIDISLFDCAVTMMLNLMNMAIVEGMKDEELRMGTKYFLATPYEPYPAGDGKLVNV
CCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCEEEEECCCCCCCCCCCCEEEE
VVATEWHWKEFCKAVGLEELLDDPRFATNQQRLKHREQLERIIIEKFREKPRDDWIEILL
EEECCHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KAGVPCGAVNTIQEVIEHPQTKHRKTVVEVDYPELGKIKLFNNPVKFSGFEVEVRRPPKL
HCCCCCCHHHHHHHHHHCCCHHHCCEEEEECCCCCCEEEEECCCCEECCEEEEECCCCCC
GEHTEEILKSIGLSEEEIADLRA
CHHHHHHHHHCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]