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Identifier: 11498474

GI number: 11498474

Start: 773034

End: 774377

Strand: Reverse

Name: Not Available

Synonym: AF0868

Alternate gene names: 11498474

Gene position: 774377-773034 (Counterclockwise)

Preceding gene: 11498475

Following gene: 11498473

Centisome position: 35.55

GC content: 53.94

Gene sequence:

>1344_bases
GTGATAGCCATCGAAAAAGCTCTTGAGGAAATCAGGGCTGCTGGGATAGCGGTCTCCACAAACATGGAGGACAGAATTGC
CTACTGCAAGGACTACAATCCCCTTCACCTTCCCAAGCTGCTCAGGCGAGAGTTTTCTGCAATGCCTGACGCTGTTGTTT
TCCCGAAGAGCACTGAGGAGGTTTCAGTCATTCTCAAGGTCGCAAACACCTACGGCATACCTGTGTACGTTTTCGGCGGT
GGGAGCGGGGTTATAGATGCAGCAACTCCCTACGAGGGGGGAATAGCTCTCTCCACGCTCTCCCTCGACCAGATAGAGAT
TGATGAGGAGAACATGGTTGTTAGAGCGGGAGCTGGGGTTGTTGGGGGAAGGCTGGAGAAGATTCTGAACCATCGGGGCT
TCACGCTCCGCCACTCTCCCCAGAGCCTCTACTGCTCGACCGTTGGCGGCTGGGTTGCTACGGCAGCGAGCGGGCAGTTC
TCAACTGGCTACGGCAACATCGAGAACCTTCTTGTCTCCCTAACGGCTGTTCTCCCGGATGGTGAAGTGGTTACGGAGAG
GGCAACTCCCAGAAGGGCTGGGCCCGATTTAAAGAAAATTTTTGTGGGAAGCGAGGGGCTGCTCGGTGTTGTTACCGAAG
CGGTAATGAAGATTTTTCCATTGCCGGAAGAGTTTCTAACGCTCTCAGTCGAATACGATGGTATTGGTGAGGCTGTGAGG
GATGCAAAGGCTTTGATGCAGCTAAGACCAGCTCTCATGAGAATTTTCGACGATGAGGAGAGTCTGAGGTACTTCGACTC
GGAAAGCTTCACTCTGATAGCGGTTTTCGAGGGAAGGGCTGCGTCTGCAAAGCTGAAGGAGGCCAGAAATCTCGTTAGGG
GAAGGTTGGTTGAGGGAAGGGCGGAGAAGTGGCTTGAGAAGAGGTTCGACGTTTCGGATATAAGCCGAATCGTCCCCCTC
GGCTTCATCTTCGACACCATAGAGGTTGCGTGCTTCTGGAAGGATGCGGAGAGAGTTTACTCAGAGGTTTTGAAGGCCAT
AAGGAGCGTTGAGGGAACAGTCACAGCCTCAGCCCACGCATCGCACTTCTACGAGAGCGGTTTGTGCTTCTACTTCACCT
TTGCCGGTTTGCCGGCAGACATAGAGAGCTACTACTTTGAAGTATGGAGGAGGGCCATCGAGGCTTCGCTGAAGAACGGT
GGGAATCTGACGCACCACCACGGCGTGGGGAGGTTGAGGAAGAGGTGGCTTTCGGCAGAGATTGGGGGATACTATCCTCT
GCTGAGAGACCTGAAGAGCGTTCTGGACAGGAGGAACATCCTCAACAGGGGGGTGATGCTGTGA

Upstream 100 bases:

>100_bases
AGCTCGGCGCTGATGCAGTGGTAAACGTTCGATTCACAACTTCACAAACAATGGCTGGAGCTGCTGAACTTCTCGCCTAC
GGAACGGCTGTGAGGCTGAG

Downstream 100 bases:

>100_bases
TAAATCCGAAGGTCATAACGAGAATTCTGGCCAACACCGACCTGAAGACGAAAATGAGGCTGGCAAAGGTGGTTCCAAAG
CTCGGCAAGTCTGATGACGT

Product: alkyldihydroxyacetonephosphate synthase

Products: alkyl-glycerone 3-phosphate; long-chain acid anion

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MIAIEKALEEIRAAGIAVSTNMEDRIAYCKDYNPLHLPKLLRREFSAMPDAVVFPKSTEEVSVILKVANTYGIPVYVFGG
GSGVIDAATPYEGGIALSTLSLDQIEIDEENMVVRAGAGVVGGRLEKILNHRGFTLRHSPQSLYCSTVGGWVATAASGQF
STGYGNIENLLVSLTAVLPDGEVVTERATPRRAGPDLKKIFVGSEGLLGVVTEAVMKIFPLPEEFLTLSVEYDGIGEAVR
DAKALMQLRPALMRIFDDEESLRYFDSESFTLIAVFEGRAASAKLKEARNLVRGRLVEGRAEKWLEKRFDVSDISRIVPL
GFIFDTIEVACFWKDAERVYSEVLKAIRSVEGTVTASAHASHFYESGLCFYFTFAGLPADIESYYFEVWRRAIEASLKNG
GNLTHHHGVGRLRKRWLSAEIGGYYPLLRDLKSVLDRRNILNRGVML

Sequences:

>Translated_447_residues
MIAIEKALEEIRAAGIAVSTNMEDRIAYCKDYNPLHLPKLLRREFSAMPDAVVFPKSTEEVSVILKVANTYGIPVYVFGG
GSGVIDAATPYEGGIALSTLSLDQIEIDEENMVVRAGAGVVGGRLEKILNHRGFTLRHSPQSLYCSTVGGWVATAASGQF
STGYGNIENLLVSLTAVLPDGEVVTERATPRRAGPDLKKIFVGSEGLLGVVTEAVMKIFPLPEEFLTLSVEYDGIGEAVR
DAKALMQLRPALMRIFDDEESLRYFDSESFTLIAVFEGRAASAKLKEARNLVRGRLVEGRAEKWLEKRFDVSDISRIVPL
GFIFDTIEVACFWKDAERVYSEVLKAIRSVEGTVTASAHASHFYESGLCFYFTFAGLPADIESYYFEVWRRAIEASLKNG
GNLTHHHGVGRLRKRWLSAEIGGYYPLLRDLKSVLDRRNILNRGVML
>Mature_447_residues
MIAIEKALEEIRAAGIAVSTNMEDRIAYCKDYNPLHLPKLLRREFSAMPDAVVFPKSTEEVSVILKVANTYGIPVYVFGG
GSGVIDAATPYEGGIALSTLSLDQIEIDEENMVVRAGAGVVGGRLEKILNHRGFTLRHSPQSLYCSTVGGWVATAASGQF
STGYGNIENLLVSLTAVLPDGEVVTERATPRRAGPDLKKIFVGSEGLLGVVTEAVMKIFPLPEEFLTLSVEYDGIGEAVR
DAKALMQLRPALMRIFDDEESLRYFDSESFTLIAVFEGRAASAKLKEARNLVRGRLVEGRAEKWLEKRFDVSDISRIVPL
GFIFDTIEVACFWKDAERVYSEVLKAIRSVEGTVTASAHASHFYESGLCFYFTFAGLPADIESYYFEVWRRAIEASLKNG
GNLTHHHGVGRLRKRWLSAEIGGYYPLLRDLKSVLDRRNILNRGVML

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI4501993, Length=505, Percent_Identity=30.2970297029703, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI37595756, Length=433, Percent_Identity=25.1732101616628, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI37595754, Length=456, Percent_Identity=23.6842105263158, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI119964728, Length=183, Percent_Identity=28.9617486338798, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI48994907, Length=432, Percent_Identity=31.712962962963, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1789351, Length=433, Percent_Identity=26.0969976905312, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1787977, Length=302, Percent_Identity=26.4900662251656, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17556096, Length=492, Percent_Identity=30.6910569105691, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI71992373, Length=485, Percent_Identity=27.6288659793814, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71992381, Length=485, Percent_Identity=27.0103092783505, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71992392, Length=392, Percent_Identity=26.530612244898, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17534361, Length=223, Percent_Identity=27.8026905829596, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320027, Length=478, Percent_Identity=25.5230125523013, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6320023, Length=250, Percent_Identity=28, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320764, Length=173, Percent_Identity=29.4797687861272, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24653753, Length=485, Percent_Identity=30.1030927835052, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI18921117, Length=427, Percent_Identity=25.0585480093677, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24639277, Length=427, Percent_Identity=25.0585480093677, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24639275, Length=427, Percent_Identity=25.0585480093677, Blast_Score=92, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: 2.5.1.26

Molecular weight: Translated: 49415; Mature: 49415

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAIEKALEEIRAAGIAVSTNMEDRIAYCKDYNPLHLPKLLRREFSAMPDAVVFPKSTEE
CCCHHHHHHHHHHCCEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEECCCCCHH
VSVILKVANTYGIPVYVFGGGSGVIDAATPYEGGIALSTLSLDQIEIDEENMVVRAGAGV
HHHHHEECCCCCCEEEEEECCCCCEECCCCCCCCEEEEEEECCEEEECCCCEEEEECCCH
VGGRLEKILNHRGFTLRHSPQSLYCSTVGGWVATAASGQFSTGYGNIENLLVSLTAVLPD
HHHHHHHHHHCCCCEEECCCCHHHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHHCCCC
GEVVTERATPRRAGPDLKKIFVGSEGLLGVVTEAVMKIFPLPEEFLTLSVEYDGIGEAVR
CCEEECCCCCCCCCCCHHEEEECCCCHHHHHHHHHHHHCCCCHHHEEEEEEECCHHHHHH
DAKALMQLRPALMRIFDDEESLRYFDSESFTLIAVFEGRAASAKLKEARNLVRGRLVEGR
HHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCH
AEKWLEKRFDVSDISRIVPLGFIFDTIEVACFWKDAERVYSEVLKAIRSVEGTVTASAHA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHCCCCEEECHHH
SHFYESGLCFYFTFAGLPADIESYYFEVWRRAIEASLKNGGNLTHHHGVGRLRKRWLSAE
HHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
IGGYYPLLRDLKSVLDRRNILNRGVML
CCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIAIEKALEEIRAAGIAVSTNMEDRIAYCKDYNPLHLPKLLRREFSAMPDAVVFPKSTEE
CCCHHHHHHHHHHCCEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEECCCCCHH
VSVILKVANTYGIPVYVFGGGSGVIDAATPYEGGIALSTLSLDQIEIDEENMVVRAGAGV
HHHHHEECCCCCCEEEEEECCCCCEECCCCCCCCEEEEEEECCEEEECCCCEEEEECCCH
VGGRLEKILNHRGFTLRHSPQSLYCSTVGGWVATAASGQFSTGYGNIENLLVSLTAVLPD
HHHHHHHHHHCCCCEEECCCCHHHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHHCCCC
GEVVTERATPRRAGPDLKKIFVGSEGLLGVVTEAVMKIFPLPEEFLTLSVEYDGIGEAVR
CCEEECCCCCCCCCCCHHEEEECCCCHHHHHHHHHHHHCCCCHHHEEEEEEECCHHHHHH
DAKALMQLRPALMRIFDDEESLRYFDSESFTLIAVFEGRAASAKLKEARNLVRGRLVEGR
HHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCH
AEKWLEKRFDVSDISRIVPLGFIFDTIEVACFWKDAERVYSEVLKAIRSVEGTVTASAHA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHCCCCEEECHHH
SHFYESGLCFYFTFAGLPADIESYYFEVWRRAIEASLKNGGNLTHHHGVGRLRKRWLSAE
HHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
IGGYYPLLRDLKSVLDRRNILNRGVML
CCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 1-acyl-glycerone 3-phosphate; long-chain alcohol

Specific reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = an alkyl-glycerone 3-phosphate + a long-chain acid anion

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]