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Identifier: 11498468

GI number: 11498468

Start: 767006

End: 768454

Strand: Reverse

Name: Not Available

Synonym: AF0862

Alternate gene names: 11498468

Gene position: 768454-767006 (Counterclockwise)

Preceding gene: 11498469

Following gene: 11498466

Centisome position: 35.28

GC content: 53.55

Gene sequence:

>1449_bases
GTGAACATGGAGGGCATTTTGAAGAAGATTACGGATTACAAGTGGGAACTACCGAAGAGTTACAAGCCTGGAATGAGGGT
TCCCGCTTACTTTTACATAAGCAGGAAGCTGATGCAAATTCTTGAAAAGGATGCGGTTGAGCAGGCTGCAAACGTTGCGA
CAATGCCCGGAATACAGGTGGCATCGCTCGTCATGCCAGATGTTCACGTTGGCTACGGCTTCCCCATCGGTGGGGTTGCC
GGGTTTGATGTTAACGAGGGAGTGGTCTCACCCGGAGGAGTGGGCTTTGACATAAACTGCGGTGTAAGGCTTTTGAGGAG
CAATTTGAATGTTGAGGATGTCAAACCGCTAATCAAAAAGCTGATAGACGAGCTATTCGTTGCTGTGCCTTCGGGAGTGG
GCAGCGAGGGTAGGCTGAGGGTAAGTGATAGAGAGCTTGACGAGATTTTTGTTGAAGGCGCGAGATGGGCTGTTGAGAAC
GGCTACGGATACGAGAGGGACTTGAAGCACTGCGAGGAGGAGGGAGCTTTGGAGGGAGCGAGGCCAGAGGTTGTGAGCAA
GAAGGCGAGGGACAGAGGAAGGCCACAGCTCGGCACTCTCGGCAGCGGAAACCACTTCCTTGAGGTTCAGTATGTTGATA
AGGTCTTTGATGAGAAGGTTGCGGCAAAGTTCGGAATCGAGGAGGGAATGGTTACGGTGATGATACACTGCGGAAGCAGG
GGGCTGGGACATCAGGTCTGCACAGACTTCCTTGAGGTTCTCGACAGAGCTGTTAAAAAGTATGGAATAAAGCTGCCAGA
CAGGCAGCTTGCATGCGCCCCGATAAACAGCAAAGAGGGGCAGGATTACTTCGCAGGCATGGCTGCATCTGCCAACTACG
CATGGTGCAACAGGCAGATTATCGCCCACTGGGTGAGAGAGACCTTCCAGAAGGTAATGGGGATGAGCGAGGATGACTTG
GGCATGGAGCTTGTTTATGATGTGGCCCACAACATAGCGAAGTTCGAGGAGCACAGGGTTGATGGCAAGAAGATGAAGCT
CTGCGTCCACAGGAAGGGAGCTACAAGAGCTTTCGGGCCGGGACTGAAGGAGGTTCCGGAGGACTACAGGGATGTTGGAC
AGCCTGTCCTCATTCCGGGCAGCATGGGAACGCCGAGCTACATCCTCGTCGGGACGGAGAAGGCCATGGAAGAGACTTTC
GGCTCAACCTGCCACGGCAGCGGGAGGGTTATGAGCAGGGCTGCTGCAAAAAGAAAGCTGAGGGGCAACGTTGTGAAGCA
GAATCTCGAAAGAAAGGGAATTTATGTCAGAGCGACGCACGGAGCTTTGCTGGCTGAGGAAGCGCCTGAGGCATACAAGC
TCAGCGACGATGTTGTCGATGTAGTCCACAGAGCGGGCATTTCAAAGCTTGTGGCGAGGCTGAGGCCCTTAGGCGTTGCT
AAAGGGTAA

Upstream 100 bases:

>100_bases
CAGTTATTCTCGGCTGGGTTGCTGTAATGCCTATCACGACGTGCTGGTGGGTTGAGCTTTACAGAAGGAGGAGTAAAACT
TTAAACAGTTTCCCCAATGG

Downstream 100 bases:

>100_bases
TTTTTTTAAATTTCTTCCGAAGCATAAAGTTGATAAGCTGAAGTTCACTAAGCTTGCCTGAGCGGGGGTTGCCGAGTGGC
CAAAGGCGGTGGACTCAAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MNMEGILKKITDYKWELPKSYKPGMRVPAYFYISRKLMQILEKDAVEQAANVATMPGIQVASLVMPDVHVGYGFPIGGVA
GFDVNEGVVSPGGVGFDINCGVRLLRSNLNVEDVKPLIKKLIDELFVAVPSGVGSEGRLRVSDRELDEIFVEGARWAVEN
GYGYERDLKHCEEEGALEGARPEVVSKKARDRGRPQLGTLGSGNHFLEVQYVDKVFDEKVAAKFGIEEGMVTVMIHCGSR
GLGHQVCTDFLEVLDRAVKKYGIKLPDRQLACAPINSKEGQDYFAGMAASANYAWCNRQIIAHWVRETFQKVMGMSEDDL
GMELVYDVAHNIAKFEEHRVDGKKMKLCVHRKGATRAFGPGLKEVPEDYRDVGQPVLIPGSMGTPSYILVGTEKAMEETF
GSTCHGSGRVMSRAAAKRKLRGNVVKQNLERKGIYVRATHGALLAEEAPEAYKLSDDVVDVVHRAGISKLVARLRPLGVA
KG

Sequences:

>Translated_482_residues
MNMEGILKKITDYKWELPKSYKPGMRVPAYFYISRKLMQILEKDAVEQAANVATMPGIQVASLVMPDVHVGYGFPIGGVA
GFDVNEGVVSPGGVGFDINCGVRLLRSNLNVEDVKPLIKKLIDELFVAVPSGVGSEGRLRVSDRELDEIFVEGARWAVEN
GYGYERDLKHCEEEGALEGARPEVVSKKARDRGRPQLGTLGSGNHFLEVQYVDKVFDEKVAAKFGIEEGMVTVMIHCGSR
GLGHQVCTDFLEVLDRAVKKYGIKLPDRQLACAPINSKEGQDYFAGMAASANYAWCNRQIIAHWVRETFQKVMGMSEDDL
GMELVYDVAHNIAKFEEHRVDGKKMKLCVHRKGATRAFGPGLKEVPEDYRDVGQPVLIPGSMGTPSYILVGTEKAMEETF
GSTCHGSGRVMSRAAAKRKLRGNVVKQNLERKGIYVRATHGALLAEEAPEAYKLSDDVVDVVHRAGISKLVARLRPLGVA
KG
>Mature_482_residues
MNMEGILKKITDYKWELPKSYKPGMRVPAYFYISRKLMQILEKDAVEQAANVATMPGIQVASLVMPDVHVGYGFPIGGVA
GFDVNEGVVSPGGVGFDINCGVRLLRSNLNVEDVKPLIKKLIDELFVAVPSGVGSEGRLRVSDRELDEIFVEGARWAVEN
GYGYERDLKHCEEEGALEGARPEVVSKKARDRGRPQLGTLGSGNHFLEVQYVDKVFDEKVAAKFGIEEGMVTVMIHCGSR
GLGHQVCTDFLEVLDRAVKKYGIKLPDRQLACAPINSKEGQDYFAGMAASANYAWCNRQIIAHWVRETFQKVMGMSEDDL
GMELVYDVAHNIAKFEEHRVDGKKMKLCVHRKGATRAFGPGLKEVPEDYRDVGQPVLIPGSMGTPSYILVGTEKAMEETF
GSTCHGSGRVMSRAAAKRKLRGNVVKQNLERKGIYVRATHGALLAEEAPEAYKLSDDVVDVVHRAGISKLVARLRPLGVA
KG

Specific function: Unknown

COG id: COG1690

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0027 (rtcB) family

Homologues:

Organism=Homo sapiens, GI7657015, Length=495, Percent_Identity=49.4949494949495, Blast_Score=482, Evalue=1e-136,
Organism=Escherichia coli, GI2367224, Length=447, Percent_Identity=30.6487695749441, Blast_Score=151, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17506665, Length=495, Percent_Identity=50.9090909090909, Blast_Score=501, Evalue=1e-142,
Organism=Drosophila melanogaster, GI24585217, Length=494, Percent_Identity=50.2024291497976, Blast_Score=480, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y862_ARCFU (O29399)

Other databases:

- EMBL:   AE000782
- PIR:   F69357
- RefSeq:   NP_069696.1
- ProteinModelPortal:   O29399
- SMR:   O29399
- GeneID:   1484082
- GenomeReviews:   AE000782_GR
- KEGG:   afu:AF0862
- NMPDR:   fig|224325.1.peg.855
- TIGR:   AF_0862
- HOGENOM:   HBG364447
- OMA:   IEERGSW
- ProtClustDB:   CLSK2746634
- BioCyc:   AFUL224325:AF_0862-MONOMER
- InterPro:   IPR001233
- PANTHER:   PTHR11118

Pfam domain/function: PF01139 UPF0027; SSF103365 UPF0027

EC number: NA

Molecular weight: Translated: 53026; Mature: 53026

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMEGILKKITDYKWELPKSYKPGMRVPAYFYISRKLMQILEKDAVEQAANVATMPGIQV
CCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
ASLVMPDVHVGYGFPIGGVAGFDVNEGVVSPGGVGFDINCGVRLLRSNLNVEDVKPLIKK
HHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEECCCCHHHHHHCCCHHHHHHHHHH
LIDELFVAVPSGVGSEGRLRVSDRELDEIFVEGARWAVENGYGYERDLKHCEEEGALEGA
HHHHHHHHCCCCCCCCCEEEECHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHCCCCCC
RPEVVSKKARDRGRPQLGTLGSGNHFLEVQYVDKVFDEKVAAKFGIEEGMVTVMIHCGSR
CHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
GLGHQVCTDFLEVLDRAVKKYGIKLPDRQLACAPINSKEGQDYFAGMAASANYAWCNRQI
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHCCCCHHHHHHHH
IAHWVRETFQKVMGMSEDDLGMELVYDVAHNIAKFEEHRVDGKKMKLCVHRKGATRAFGP
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHEEEEEECCCCCCCCCC
GLKEVPEDYRDVGQPVLIPGSMGTPSYILVGTEKAMEETFGSTCHGSGRVMSRAAAKRKL
CHHHCCHHHHHCCCCEEEECCCCCCCEEEEECHHHHHHHHCCCCCCCCHHHHHHHHHHHH
RGNVVKQNLERKGIYVRATHGALLAEEAPEAYKLSDDVVDVVHRAGISKLVARLRPLGVA
HHHHHHHHHHHCCEEEEECCCCHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
KG
CC
>Mature Secondary Structure
MNMEGILKKITDYKWELPKSYKPGMRVPAYFYISRKLMQILEKDAVEQAANVATMPGIQV
CCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
ASLVMPDVHVGYGFPIGGVAGFDVNEGVVSPGGVGFDINCGVRLLRSNLNVEDVKPLIKK
HHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEECCCCHHHHHHCCCHHHHHHHHHH
LIDELFVAVPSGVGSEGRLRVSDRELDEIFVEGARWAVENGYGYERDLKHCEEEGALEGA
HHHHHHHHCCCCCCCCCEEEECHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHCCCCCC
RPEVVSKKARDRGRPQLGTLGSGNHFLEVQYVDKVFDEKVAAKFGIEEGMVTVMIHCGSR
CHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
GLGHQVCTDFLEVLDRAVKKYGIKLPDRQLACAPINSKEGQDYFAGMAASANYAWCNRQI
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHCCCCHHHHHHHH
IAHWVRETFQKVMGMSEDDLGMELVYDVAHNIAKFEEHRVDGKKMKLCVHRKGATRAFGP
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHEEEEEECCCCCCCCCC
GLKEVPEDYRDVGQPVLIPGSMGTPSYILVGTEKAMEETFGSTCHGSGRVMSRAAAKRKL
CHHHCCHHHHHCCCCEEEECCCCCCCEEEEECHHHHHHHHCCCCCCCCHHHHHHHHHHHH
RGNVVKQNLERKGIYVRATHGALLAEEAPEAYKLSDDVVDVVHRAGISKLVARLRPLGVA
HHHHHHHHHHHCCEEEEECCCCHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
KG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475