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The map label for this gene is corA

Identifier: 11498392

GI number: 11498392

Start: 699898

End: 700953

Strand: Reverse

Name: corA

Synonym: AF0786

Alternate gene names: 11498392

Gene position: 700953-699898 (Counterclockwise)

Preceding gene: 11498396

Following gene: 11498391

Centisome position: 32.18

GC content: 48.01

Gene sequence:

>1056_bases
ATGCGGATTCCAGCGACAATCAAAAAGAAGATGGCCCTTCCACCCGCAACTCCCGTCTTCACCGGCGAAAAGAAAGTTGA
GGAAACTAAAATTACTGCGGCAATTTACGACGAGAAATCGGTGGAGTTTAAGGAGCTAGAGGTGGGGGAGCTTGAAAGTG
TGGTCAGAAGCGCGCTCGCACTCAATAAAAAGCTCTGGATTGATGTCGTTGGTGTTCACGATGAAAGTCTTATCGCTAAA
ATCTGCGAATTCCTGGGAATCCACCCTCTCGCTGCTGAGGACATTCTCAACACAGCCCAGAGGGTAAAAATTGAAGACTA
CGACGACCACCTTTTTCTTGTACTTAAAATTCTGCTTTACAACGAGACCCTTGAAATTGACCAGCTCAGCCTGGTTTTGA
AGAAAAACCTTGTGGCGACGTTTGAAGAAAGAGAGTACTGGATTCTCGACTCCATCCGCTCAAGGCTTAAGTCCGGGGGG
AGAATGAGAAAGCTCGCTGGCGATTATCTTGCCTATACCATACTCGACGCGGTTGTTGACAGCTACTTCGAAGCACTTCT
GAAAATTTCGGATGAGATTGAGGTGTTGGAGGATGAGGTTGTTTCTGGGGACAGCACACTCATCGGGAAGATTCACAGCC
TGAAGAGGGAAATACTTGCCTTCAGAAACGCCGTATGGCCCCTAAGAGATGTTCTCAGCTTCTTTACCAGAGTTGAGCAC
GAGCTTATAGGTGAGGAGGTAAAGGTGTATTACAGGGACGTTTACGACCACGCTGTTCGACTCATGGAGGTTCTTGAGAC
GCAGAGAGAGCTGCTGGTGAGCTTGAGAGACTTATTTCTGTCAGCGGTCAGCAACAAGCTCAACGAGATAATGAAGGTGC
TCACTATGATTGCGACCATATTCATTCCCCTGAGCTTCATTGCGGGTGTTTATGGGATGAATTTTAAGTACATGCCTGAG
CTGGAGTGGAAGTACGGGTATCCGGCCGTTCTGACAGTTATGGCCGTCATCGCACTGGTAATGATTGCCTTCTTCAGGAG
GAAGGGGTGGTTATGA

Upstream 100 bases:

>100_bases
TCACACCTCTTTACCCTCAATCCCATCCTACTTCTTTACAAAATTAACTTCGCCAAAATCTTGGAGCAAAGCGTTATATT
TTATTAATTAAACAAAATTC

Downstream 100 bases:

>100_bases
GAAAAATCATAGTCAGGGGGAGGAAGGAAGACCTAGAGGAGATAGCGAGGGAATTGGGAGATAGAGCTTTCATTTACGAT
GACAGAATCGAGCTATACGT

Product: magnesium and cobalt transporter (corA)

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MRIPATIKKKMALPPATPVFTGEKKVEETKITAAIYDEKSVEFKELEVGELESVVRSALALNKKLWIDVVGVHDESLIAK
ICEFLGIHPLAAEDILNTAQRVKIEDYDDHLFLVLKILLYNETLEIDQLSLVLKKNLVATFEEREYWILDSIRSRLKSGG
RMRKLAGDYLAYTILDAVVDSYFEALLKISDEIEVLEDEVVSGDSTLIGKIHSLKREILAFRNAVWPLRDVLSFFTRVEH
ELIGEEVKVYYRDVYDHAVRLMEVLETQRELLVSLRDLFLSAVSNKLNEIMKVLTMIATIFIPLSFIAGVYGMNFKYMPE
LEWKYGYPAVLTVMAVIALVMIAFFRRKGWL

Sequences:

>Translated_351_residues
MRIPATIKKKMALPPATPVFTGEKKVEETKITAAIYDEKSVEFKELEVGELESVVRSALALNKKLWIDVVGVHDESLIAK
ICEFLGIHPLAAEDILNTAQRVKIEDYDDHLFLVLKILLYNETLEIDQLSLVLKKNLVATFEEREYWILDSIRSRLKSGG
RMRKLAGDYLAYTILDAVVDSYFEALLKISDEIEVLEDEVVSGDSTLIGKIHSLKREILAFRNAVWPLRDVLSFFTRVEH
ELIGEEVKVYYRDVYDHAVRLMEVLETQRELLVSLRDLFLSAVSNKLNEIMKVLTMIATIFIPLSFIAGVYGMNFKYMPE
LEWKYGYPAVLTVMAVIALVMIAFFRRKGWL
>Mature_351_residues
MRIPATIKKKMALPPATPVFTGEKKVEETKITAAIYDEKSVEFKELEVGELESVVRSALALNKKLWIDVVGVHDESLIAK
ICEFLGIHPLAAEDILNTAQRVKIEDYDDHLFLVLKILLYNETLEIDQLSLVLKKNLVATFEEREYWILDSIRSRLKSGG
RMRKLAGDYLAYTILDAVVDSYFEALLKISDEIEVLEDEVVSGDSTLIGKIHSLKREILAFRNAVWPLRDVLSFFTRVEH
ELIGEEVKVYYRDVYDHAVRLMEVLETQRELLVSLRDLFLSAVSNKLNEIMKVLTMIATIFIPLSFIAGVYGMNFKYMPE
LEWKYGYPAVLTVMAVIALVMIAFFRRKGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=64, Percent_Identity=40.625, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1787604, Length=294, Percent_Identity=19.047619047619, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 40273; Mature: 40273

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIPATIKKKMALPPATPVFTGEKKVEETKITAAIYDEKSVEFKELEVGELESVVRSALA
CCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHEEECCCCCCHHHCCHHHHHHHHHHHHH
LNKKLWIDVVGVHDESLIAKICEFLGIHPLAAEDILNTAQRVKIEDYDDHLFLVLKILLY
HCHHHEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
NETLEIDQLSLVLKKNLVATFEEREYWILDSIRSRLKSGGRMRKLAGDYLAYTILDAVVD
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
SYFEALLKISDEIEVLEDEVVSGDSTLIGKIHSLKREILAFRNAVWPLRDVLSFFTRVEH
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ELIGEEVKVYYRDVYDHAVRLMEVLETQRELLVSLRDLFLSAVSNKLNEIMKVLTMIATI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIPLSFIAGVYGMNFKYMPELEWKYGYPAVLTVMAVIALVMIAFFRRKGWL
HHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRIPATIKKKMALPPATPVFTGEKKVEETKITAAIYDEKSVEFKELEVGELESVVRSALA
CCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHEEECCCCCCHHHCCHHHHHHHHHHHHH
LNKKLWIDVVGVHDESLIAKICEFLGIHPLAAEDILNTAQRVKIEDYDDHLFLVLKILLY
HCHHHEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
NETLEIDQLSLVLKKNLVATFEEREYWILDSIRSRLKSGGRMRKLAGDYLAYTILDAVVD
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
SYFEALLKISDEIEVLEDEVVSGDSTLIGKIHSLKREILAFRNAVWPLRDVLSFFTRVEH
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ELIGEEVKVYYRDVYDHAVRLMEVLETQRELLVSLRDLFLSAVSNKLNEIMKVLTMIATI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIPLSFIAGVYGMNFKYMPELEWKYGYPAVLTVMAVIALVMIAFFRRKGWL
HHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]