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Identifier: 11498153

GI number: 11498153

Start: 492925

End: 494541

Strand: Reverse

Name: Not Available

Synonym: AF0543

Alternate gene names: NA

Gene position: 494541-492925 (Counterclockwise)

Preceding gene: 11498154

Following gene: 11498152

Centisome position: 22.7

GC content: 49.78

Gene sequence:

>1617_bases
ATGGTTTGGAGGAAGAAGGACGAGTTGATTACTGTTCAGGATATAGCCTTACCATACGAAAGGCTAGCTTACATACATCT
TCAGGATTTGCTGAAGCTCCCCCCACCCTACGACAGCGGGGATGAGCCAGAGCTTCAGGAACCAAATCCTGAGTGGAGCG
AGAAGTACGTTACTGAGCTTGACGGCTACATAGCCATAGACGAGCCTTGGAAACCGCAGAATGAGGAAGAGGAAAAGGAG
CTGGTTGAGAGGTTCCTTTCCGGGCTGAGAAAGCTCCTTGACAGGGAGGCAAACTGGACATTCTTGCAGCCTTTAATGCT
TTCCCTTGAGTACTGCGCCCGGTGCCAGACCTGCAGTGAAGCCTGTCCCATTTTCGTGTCAAGCGGGAGGAAGGAAATTT
ACAGACCAACCTACAGGTCGGAAGTATTGAGGAGGATAATCAAAAGATACCTACAGCCCACAGGTGGGTTGCTTGGTAAA
TTTACGGGTGCTGATATCGAGTTGAACGCTCTGACCGTCACAAGGCTCGCTGAACTCGCCTACAGATGCACCCTCTGCAG
AAGATGCACCCAAACCTGCCCCCTCGGAATAGACAACGGCCTGATAACGAGAGAAATAAGGAAGCTCTTCAGCCAGGAGA
TGGGAATAGCTCCTTCATCCCTGCACATGCAGGGGACAGTTCAGCACCTCGAAAAGGGCTCTTCAACGGGCTTAACCACT
GAAGGATTTAAAGACATCATCGAGTTCATTGAGGAGGAGATAGAGGAGAGAACGGGAAAGAAGATAAAGATACCCGTGGA
TGTAAAAGGAGCGGACATCCTTCTCTACCACAATGCAGGAGAATACCTCAGCTGGCCGGAAAACATCGCTGCCTTCGCCA
TAATCTTCGAGGAAGCAGGGCTGGACTGGACGCTTAGCAGTGAGATGGTTGGCTACGATGCTGTTAACTACGGAGTCTGG
TATGATGACGTGCAGTTCTCAAGGATAGCCCTCAAACACGCTGAAATCGCAAGAAAGCTTGATGTAAACAGAATTGTGGT
TGGAGAGTGCGGGCATGCACACAAAGCTCTGACAGTCATTGCCGATAGAATTTTCGTAGATGAGTACCAGATACCGAGAG
AAAGCTGCCTGCCATTGCTCTGGGACATTGTGAGGAAAAAGAAGCTTAACCTCGACCCGGAGAAGAATAACTTCCCGGTC
ACACTGCACGATCCGTGCAACGTTGTTAGGCTGATGGGTATTGTCGAGCCGCAGCGCAGGATTCTCAACGAAATCTGCCC
GCAGTTCAGGGAAATGCATCCAAACGGGGTTTACAACTACTGCTGTGGTGGCGGTAGCGGTTTCGCCATAATGAACTCCA
TGAACTTCCCTGAGTTCAGGGTTAAGGTGGCGAGCAGGATGAAGTTTAAGCAAATTCTTGATGCTTTCCAGGACAGCATC
TCCCCCGAAATAAACAAGTACGTCTGCGCACCCTGCAGCAACTGCAAGGGGGCAATCAGGGACATTCTCACCCACTACAA
CGCAACCGAGAAATGCGGAATCTACTACGGCGGGTTGGTGGAGCTAATTGTAAATGCGATGGTTGATATAGAAGAACCAT
TCATTGAAATGTATTAA

Upstream 100 bases:

>100_bases
ACAGGTTCAATATGAAGTGTGTGGGAATCCCTGAGATTGTTTTGAACTGTGTTGAGAACGTTGAAAAGAAAATTCTCAGT
ATTGTTTAGGAGGTGGTTTA

Downstream 100 bases:

>100_bases
ACTTTTTTAAAATATTTTTTGCTCCCTGAAATTTTTCTTCCTCTAGCTCATCGAGCAATTCTTCGACTCCAAACCGAGTT
TCTTCAGATAACTCTTAAGG

Product: hypothetical protein

Products: NA

Alternate protein names: HMC operon ORF 6 [H]

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MVWRKKDELITVQDIALPYERLAYIHLQDLLKLPPPYDSGDEPELQEPNPEWSEKYVTELDGYIAIDEPWKPQNEEEEKE
LVERFLSGLRKLLDREANWTFLQPLMLSLEYCARCQTCSEACPIFVSSGRKEIYRPTYRSEVLRRIIKRYLQPTGGLLGK
FTGADIELNALTVTRLAELAYRCTLCRRCTQTCPLGIDNGLITREIRKLFSQEMGIAPSSLHMQGTVQHLEKGSSTGLTT
EGFKDIIEFIEEEIEERTGKKIKIPVDVKGADILLYHNAGEYLSWPENIAAFAIIFEEAGLDWTLSSEMVGYDAVNYGVW
YDDVQFSRIALKHAEIARKLDVNRIVVGECGHAHKALTVIADRIFVDEYQIPRESCLPLLWDIVRKKKLNLDPEKNNFPV
TLHDPCNVVRLMGIVEPQRRILNEICPQFREMHPNGVYNYCCGGGSGFAIMNSMNFPEFRVKVASRMKFKQILDAFQDSI
SPEINKYVCAPCSNCKGAIRDILTHYNATEKCGIYYGGLVELIVNAMVDIEEPFIEMY

Sequences:

>Translated_538_residues
MVWRKKDELITVQDIALPYERLAYIHLQDLLKLPPPYDSGDEPELQEPNPEWSEKYVTELDGYIAIDEPWKPQNEEEEKE
LVERFLSGLRKLLDREANWTFLQPLMLSLEYCARCQTCSEACPIFVSSGRKEIYRPTYRSEVLRRIIKRYLQPTGGLLGK
FTGADIELNALTVTRLAELAYRCTLCRRCTQTCPLGIDNGLITREIRKLFSQEMGIAPSSLHMQGTVQHLEKGSSTGLTT
EGFKDIIEFIEEEIEERTGKKIKIPVDVKGADILLYHNAGEYLSWPENIAAFAIIFEEAGLDWTLSSEMVGYDAVNYGVW
YDDVQFSRIALKHAEIARKLDVNRIVVGECGHAHKALTVIADRIFVDEYQIPRESCLPLLWDIVRKKKLNLDPEKNNFPV
TLHDPCNVVRLMGIVEPQRRILNEICPQFREMHPNGVYNYCCGGGSGFAIMNSMNFPEFRVKVASRMKFKQILDAFQDSI
SPEINKYVCAPCSNCKGAIRDILTHYNATEKCGIYYGGLVELIVNAMVDIEEPFIEMY
>Mature_538_residues
MVWRKKDELITVQDIALPYERLAYIHLQDLLKLPPPYDSGDEPELQEPNPEWSEKYVTELDGYIAIDEPWKPQNEEEEKE
LVERFLSGLRKLLDREANWTFLQPLMLSLEYCARCQTCSEACPIFVSSGRKEIYRPTYRSEVLRRIIKRYLQPTGGLLGK
FTGADIELNALTVTRLAELAYRCTLCRRCTQTCPLGIDNGLITREIRKLFSQEMGIAPSSLHMQGTVQHLEKGSSTGLTT
EGFKDIIEFIEEEIEERTGKKIKIPVDVKGADILLYHNAGEYLSWPENIAAFAIIFEEAGLDWTLSSEMVGYDAVNYGVW
YDDVQFSRIALKHAEIARKLDVNRIVVGECGHAHKALTVIADRIFVDEYQIPRESCLPLLWDIVRKKKLNLDPEKNNFPV
TLHDPCNVVRLMGIVEPQRRILNEICPQFREMHPNGVYNYCCGGGSGFAIMNSMNFPEFRVKVASRMKFKQILDAFQDSI
SPEINKYVCAPCSNCKGAIRDILTHYNATEKCGIYYGGLVELIVNAMVDIEEPFIEMY

Specific function: HMWC (high-molecular-weight cytochrome c precursor), ORF2, ORF3, ORF4, ORF5, ORF6 in the HMC operon form a transmembrane protein complex that allows electron flow from the periplasmic hydrogenase to the cytoplasmic enzymes that catalyze reduction of sulfa

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017900
- InterPro:   IPR004017
- InterPro:   IPR012285 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: NA

Molecular weight: Translated: 61581; Mature: 61581

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWRKKDELITVQDIALPYERLAYIHLQDLLKLPPPYDSGDEPELQEPNPEWSEKYVTEL
CCCCCCCCEEEEHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHC
DGYIAIDEPWKPQNEEEEKELVERFLSGLRKLLDREANWTFLQPLMLSLEYCARCQTCSE
CCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
ACPIFVSSGRKEIYRPTYRSEVLRRIIKRYLQPTGGLLGKFTGADIELNALTVTRLAELA
HCCEEECCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHH
YRCTLCRRCTQTCPLGIDNGLITREIRKLFSQEMGIAPSSLHMQGTVQHLEKGSSTGLTT
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCH
EGFKDIIEFIEEEIEERTGKKIKIPVDVKGADILLYHNAGEYLSWPENIAAFAIIFEEAG
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHEEEEEEECCC
LDWTLSSEMVGYDAVNYGVWYDDVQFSRIALKHAEIARKLDVNRIVVGECGHAHKALTVI
CCEEECCCCCCCCCEECCCEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
ADRIFVDEYQIPRESCLPLLWDIVRKKKLNLDPEKNNFPVTLHDPCNVVRLMGIVEPQRR
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHCCCHHHH
ILNEICPQFREMHPNGVYNYCCGGGSGFAIMNSMNFPEFRVKVASRMKFKQILDAFQDSI
HHHHHHHHHHHCCCCCCEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHC
SPEINKYVCAPCSNCKGAIRDILTHYNATEKCGIYYGGLVELIVNAMVDIEEPFIEMY
CCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MVWRKKDELITVQDIALPYERLAYIHLQDLLKLPPPYDSGDEPELQEPNPEWSEKYVTEL
CCCCCCCCEEEEHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHC
DGYIAIDEPWKPQNEEEEKELVERFLSGLRKLLDREANWTFLQPLMLSLEYCARCQTCSE
CCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
ACPIFVSSGRKEIYRPTYRSEVLRRIIKRYLQPTGGLLGKFTGADIELNALTVTRLAELA
HCCEEECCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHH
YRCTLCRRCTQTCPLGIDNGLITREIRKLFSQEMGIAPSSLHMQGTVQHLEKGSSTGLTT
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCH
EGFKDIIEFIEEEIEERTGKKIKIPVDVKGADILLYHNAGEYLSWPENIAAFAIIFEEAG
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHEEEEEEECCC
LDWTLSSEMVGYDAVNYGVWYDDVQFSRIALKHAEIARKLDVNRIVVGECGHAHKALTVI
CCEEECCCCCCCCCEECCCEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
ADRIFVDEYQIPRESCLPLLWDIVRKKKLNLDPEKNNFPVTLHDPCNVVRLMGIVEPQRR
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHCCCHHHH
ILNEICPQFREMHPNGVYNYCCGGGSGFAIMNSMNFPEFRVKVASRMKFKQILDAFQDSI
HHHHHHHHHHHCCCCCCEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHC
SPEINKYVCAPCSNCKGAIRDILTHYNATEKCGIYYGGLVELIVNAMVDIEEPFIEMY
CCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8335628 [H]