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The map label for this gene is exsB

Identifier: 11498054

GI number: 11498054

Start: 397392

End: 398111

Strand: Reverse

Name: exsB

Synonym: AF0442

Alternate gene names: 11498054

Gene position: 398111-397392 (Counterclockwise)

Preceding gene: 11498057

Following gene: 11498053

Centisome position: 18.28

GC content: 50.83

Gene sequence:

>720_bases
ATGAAAGCCGTAATGCTCCTGAGTGGTGGGATTGATTCCTCAACACTCCTTTACTACTTGCTCGACGGAGGTTACGAGGT
TCACGCTCTAACGTTCTTCTACGGCCAAAAGCATTCCAAGGAAATCGAAAGCGCCGAAAAAGTTGCAAAGGCTGCTAAAG
TTCGACATCTCAAGGTCGACATCTCTACAATTCACGACCTCATCTCTTACGGGGCCTTGACGGGGGAAGAGGAGGTTCCA
AAGGCATTTTACAGCGAGGAAGTTCAGCGGAGAACAATCGTTCCAAACAGAAACATGATTCTGCTGTCAATAGCAGCAGG
CTATGCGGTAAAAATCGGAGCGAAGGAAGTGCACTATGCAGCACACCTCAGCGACTACAGCATCTACCCAGACTGCAGGA
AGGAGTTCGTTAAAGCTCTTGATACTGCAGTTTATCTTGCAAACATCTGGACGCCTGTGGAGGTTAGGGCGCCCTTCGTG
GACATGACCAAGGCGGACATCGTGAGGCTTGGTTTAAAGCTGGGAGTTCCCTACGAGCTTACCTGGAGCTGCTATGAAGG
GGGCGATAGGCCTTGCTTGAGCTGCGGGACGTGCCTTGAGCGCACTGAAGCCTTCCTTGCCAACGGAGTGAAGGACCCTC
TCCTCAGCGATGAGGAATGGAAAAATGCGGTGAAAATTTACGAGGAGATGAGGGCGAGGAATGAGGGCAAATCTGATTGA

Upstream 100 bases:

>100_bases
CTCGGCAACCCCCGCTCAGATGAAAAATTCTGCATAGGATTTATGAATATTGTGGTTTAAAGGGCGATGACTTCATATAA
CTTTGAAATCCACCTTCTAC

Downstream 100 bases:

>100_bases
AATTTTCGAGTCGATTCAGGGAGAGGGGTTTTACATTGGCGTCAGGCAGCTTTTCGTGAGATTTGCGGGATGCAATCTTA
ACTGCTACTACTGCGACACA

Product: succinoglycan biosynthesis regulator (exsB)

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; Archaeosine biosynthesis protein queC; PreQ(0) synthase

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MKAVMLLSGGIDSSTLLYYLLDGGYEVHALTFFYGQKHSKEIESAEKVAKAAKVRHLKVDISTIHDLISYGALTGEEEVP
KAFYSEEVQRRTIVPNRNMILLSIAAGYAVKIGAKEVHYAAHLSDYSIYPDCRKEFVKALDTAVYLANIWTPVEVRAPFV
DMTKADIVRLGLKLGVPYELTWSCYEGGDRPCLSCGTCLERTEAFLANGVKDPLLSDEEWKNAVKIYEEMRARNEGKSD

Sequences:

>Translated_239_residues
MKAVMLLSGGIDSSTLLYYLLDGGYEVHALTFFYGQKHSKEIESAEKVAKAAKVRHLKVDISTIHDLISYGALTGEEEVP
KAFYSEEVQRRTIVPNRNMILLSIAAGYAVKIGAKEVHYAAHLSDYSIYPDCRKEFVKALDTAVYLANIWTPVEVRAPFV
DMTKADIVRLGLKLGVPYELTWSCYEGGDRPCLSCGTCLERTEAFLANGVKDPLLSDEEWKNAVKIYEEMRARNEGKSD
>Mature_239_residues
MKAVMLLSGGIDSSTLLYYLLDGGYEVHALTFFYGQKHSKEIESAEKVAKAAKVRHLKVDISTIHDLISYGALTGEEEVP
KAFYSEEVQRRTIVPNRNMILLSIAAGYAVKIGAKEVHYAAHLSDYSIYPDCRKEFVKALDTAVYLANIWTPVEVRAPFV
DMTKADIVRLGLKLGVPYELTWSCYEGGDRPCLSCGTCLERTEAFLANGVKDPLLSDEEWKNAVKIYEEMRARNEGKSD

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=217, Percent_Identity=36.405529953917, Blast_Score=105, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_ARCFU (O29807)

Other databases:

- EMBL:   AE000782
- PIR:   B69305
- RefSeq:   NP_069278.1
- ProteinModelPortal:   O29807
- SMR:   O29807
- GeneID:   1483658
- GenomeReviews:   AE000782_GR
- KEGG:   afu:AF0442
- NMPDR:   fig|224325.1.peg.437
- TIGR:   AF_0442
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- ProtClustDB:   CLSK2746436
- BioCyc:   AFUL224325:AF_0442-MONOMER
- HAMAP:   MF_01633_A
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 26726; Mature: 26726

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVMLLSGGIDSSTLLYYLLDGGYEVHALTFFYGQKHSKEIESAEKVAKAAKVRHLKVD
CCEEEEEECCCCCCEEEEEEECCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEH
ISTIHDLISYGALTGEEEVPKAFYSEEVQRRTIVPNRNMILLSIAAGYAVKIGAKEVHYA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEECCHHHHHH
AHLSDYSIYPDCRKEFVKALDTAVYLANIWTPVEVRAPFVDMTKADIVRLGLKLGVPYEL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHCCCCEEE
TWSCYEGGDRPCLSCGTCLERTEAFLANGVKDPLLSDEEWKNAVKIYEEMRARNEGKSD
EEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKAVMLLSGGIDSSTLLYYLLDGGYEVHALTFFYGQKHSKEIESAEKVAKAAKVRHLKVD
CCEEEEEECCCCCCEEEEEEECCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEH
ISTIHDLISYGALTGEEEVPKAFYSEEVQRRTIVPNRNMILLSIAAGYAVKIGAKEVHYA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEECCHHHHHH
AHLSDYSIYPDCRKEFVKALDTAVYLANIWTPVEVRAPFVDMTKADIVRLGLKLGVPYEL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHCCCCEEE
TWSCYEGGDRPCLSCGTCLERTEAFLANGVKDPLLSDEEWKNAVKIYEEMRARNEGKSD
EEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475