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The map label for this gene is cdhD

Identifier: 11497989

GI number: 11497989

Start: 341214

End: 342572

Strand: Reverse

Name: cdhD

Synonym: AF0377

Alternate gene names: 11497989

Gene position: 342572-341214 (Counterclockwise)

Preceding gene: 11497990

Following gene: 11497988

Centisome position: 15.73

GC content: 54.67

Gene sequence:

>1359_bases
TTGAAAAAGTTCACGCTTGAGGAGTTTTTGGATTTGCTGAAAAAGTATAATGTAGAGGAGATAGAAGGGGTGAAAATTGA
GGGCGACCTCGAAATAGAGTTCGAGGGATCGTCGATAGACCTATCAGCAATTGCCCCTCTTTACTCAATGCTTTCCGAAT
TCGGTAACTTCCTGTATCACGCAAACATGGCACTCGGCTATCTGCAGAGGCTTTCTGCAGCCCTTGGCATCCCAACACCC
TTCGCTGCACAGCCTCAGCTTGCCCCTGCGGCTCCTGCTGCACCGGCTGAGGTTCCGGCAGTCGAGGAGCTGAAGATTCC
AGCAGAGCTTGTAAGGGCAAAGTTTGAGCCATACAAGGAGGAGTATCCGGGCAAGATAGAGGAGGTTGTTCTTGGCGCAA
CCAAGGCTGATGGGGGAACCAGGGAGTACACTGTCACGCTTGGTGGAGAGAGGAGTCTCGCTTTCTACACCTTCGACGCC
CCACAGCCCCACCTTCCCGCAATAGCCATTGACGTCTTCGACAGAAGGCCCATGCTCGCAAAGGCGGTGAGGATGCACTA
CGAGGATGTGCTGGACAACCCTGCAGAGTGGGCGAGGAAGTGTGTTAAGAAGTTCGGTGCTGACCTAGTAACGCTCCACC
TCATCAGCACGGACCCCCTGCTGGACGACACACCTGCAAGCGAGGCCGTGAAGGTTCTTGAGGACGTTCTGCAGGCGGTG
AAGTGCCCCATAATCGTTGGAGGTAGCGGAAACAAGGAGAAGGACCCCGAGGTTCTTGAGAAGGCCGCGGAGGTAGCTGA
GGGAGAGAGAATCATGCTTGCCTCAGCAACTCTCGACATGGACTGGGAAAGGATTGCCAACGCAGCCAAGAAGTACGGCC
ATGTCGTTTTGAGCTGGACCCAGATGGACATAAACAACCAGAAGACGCTCAACAGGTACCTGCTGAAGAGGGTCGAGATG
CCGAGAGACAGCATCGTCATGGACCCAACGACCGCAGCCCTCGGTTATGGCCTTGACTATGCCTTCACGAACATGGAGAG
AATCAGAATCAGCGGTTTGAAGGGAGACACAGACCTGAACTTCCCGATATCAAGCGGTACGACCAACGCGTGGGGAGCGA
GAGAGGCCTGGATGGTGGACTCACCGATTGAAGAGGACACGCCCTGGGGGCCAAGAGAGCTCAGAGGCCCAATCTGGGAG
ATTATAACTGGTCTGACACTCTCCCTTGCCGGAGTCGATCTCTTCATGATGATGCATCCAGTAGCAGTTGCCGTCCTCAA
GGAGGTCTTCAACACACTCGGCGGTAAGGTTAGCGGAGGAGTGGCTGACCCTGGCGAGTGGATTTTCATGGAGGTGTAA

Upstream 100 bases:

>100_bases
AACCTGTAAGCAAGATAGACAAGAATTCTGAAGTCTATAGGAAAATGAAGGATGTAGCTAATTTAATGCTCAATTTGTCA
GCCAAAGCGAGGTGATTAAT

Downstream 100 bases:

>100_bases
TGAATGAAGGTAAAGAGCCCCCTTGAGGTTTACAACTACCTGCCGAGAACTAACTGCGGAGAATGCGGCTTCGACACCTG
CATGAGCTTTGCAGCCCACA

Product: acetyl-CoA decarbonylase/synthase complex subunit delta

Products: CO2; AH2

Alternate protein names: ACDS complex subunit delta; Corrinoid/iron-sulfur component small subunit

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKKFTLEEFLDLLKKYNVEEIEGVKIEGDLEIEFEGSSIDLSAIAPLYSMLSEFGNFLYHANMALGYLQRLSAALGIPTP
FAAQPQLAPAAPAAPAEVPAVEELKIPAELVRAKFEPYKEEYPGKIEEVVLGATKADGGTREYTVTLGGERSLAFYTFDA
PQPHLPAIAIDVFDRRPMLAKAVRMHYEDVLDNPAEWARKCVKKFGADLVTLHLISTDPLLDDTPASEAVKVLEDVLQAV
KCPIIVGGSGNKEKDPEVLEKAAEVAEGERIMLASATLDMDWERIANAAKKYGHVVLSWTQMDINNQKTLNRYLLKRVEM
PRDSIVMDPTTAALGYGLDYAFTNMERIRISGLKGDTDLNFPISSGTTNAWGAREAWMVDSPIEEDTPWGPRELRGPIWE
IITGLTLSLAGVDLFMMMHPVAVAVLKEVFNTLGGKVSGGVADPGEWIFMEV

Sequences:

>Translated_452_residues
MKKFTLEEFLDLLKKYNVEEIEGVKIEGDLEIEFEGSSIDLSAIAPLYSMLSEFGNFLYHANMALGYLQRLSAALGIPTP
FAAQPQLAPAAPAAPAEVPAVEELKIPAELVRAKFEPYKEEYPGKIEEVVLGATKADGGTREYTVTLGGERSLAFYTFDA
PQPHLPAIAIDVFDRRPMLAKAVRMHYEDVLDNPAEWARKCVKKFGADLVTLHLISTDPLLDDTPASEAVKVLEDVLQAV
KCPIIVGGSGNKEKDPEVLEKAAEVAEGERIMLASATLDMDWERIANAAKKYGHVVLSWTQMDINNQKTLNRYLLKRVEM
PRDSIVMDPTTAALGYGLDYAFTNMERIRISGLKGDTDLNFPISSGTTNAWGAREAWMVDSPIEEDTPWGPRELRGPIWE
IITGLTLSLAGVDLFMMMHPVAVAVLKEVFNTLGGKVSGGVADPGEWIFMEV
>Mature_452_residues
MKKFTLEEFLDLLKKYNVEEIEGVKIEGDLEIEFEGSSIDLSAIAPLYSMLSEFGNFLYHANMALGYLQRLSAALGIPTP
FAAQPQLAPAAPAAPAEVPAVEELKIPAELVRAKFEPYKEEYPGKIEEVVLGATKADGGTREYTVTLGGERSLAFYTFDA
PQPHLPAIAIDVFDRRPMLAKAVRMHYEDVLDNPAEWARKCVKKFGADLVTLHLISTDPLLDDTPASEAVKVLEDVLQAV
KCPIIVGGSGNKEKDPEVLEKAAEVAEGERIMLASATLDMDWERIANAAKKYGHVVLSWTQMDINNQKTLNRYLLKRVEM
PRDSIVMDPTTAALGYGLDYAFTNMERIRISGLKGDTDLNFPISSGTTNAWGAREAWMVDSPIEEDTPWGPRELRGPIWE
IITGLTLSLAGVDLFMMMHPVAVAVLKEVFNTLGGKVSGGVADPGEWIFMEV

Specific function: Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex

COG id: COG2069

COG function: function code C; CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CdhD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDD_ARCFU (O29870)

Other databases:

- EMBL:   AE000782
- PIR:   A69297
- RefSeq:   NP_069213.1
- ProteinModelPortal:   O29870
- SMR:   O29870
- GeneID:   1483592
- GenomeReviews:   AE000782_GR
- KEGG:   afu:AF0377
- NMPDR:   fig|224325.1.peg.372
- TIGR:   AF_0377
- HOGENOM:   HBG456967
- OMA:   IVMDPTT
- ProtClustDB:   PRK04452
- BioCyc:   AFUL224325:AF_0377-MONOMER
- HAMAP:   MF_01135
- InterPro:   IPR016041
- InterPro:   IPR004486
- InterPro:   IPR011005
- InterPro:   IPR000489
- Gene3D:   G3DSA:3.20.20.20
- TIGRFAMs:   TIGR00381

Pfam domain/function: PF03599 CdhD; SSF51717 DHP_synth_like

EC number: 1.2.99.2

Molecular weight: Translated: 49748; Mature: 49748

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFTLEEFLDLLKKYNVEEIEGVKIEGDLEIEFEGSSIDLSAIAPLYSMLSEFGNFLYH
CCCCCHHHHHHHHHHCCCCHHCCEEEECCEEEEECCCEECHHHHHHHHHHHHHHHHHHHH
ANMALGYLQRLSAALGIPTPFAAQPQLAPAAPAAPAEVPAVEELKIPAELVRAKFEPYKE
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHCCCHHH
EYPGKIEEVVLGATKADGGTREYTVTLGGERSLAFYTFDAPQPHLPAIAIDVFDRRPMLA
HCCCHHHHHEEECCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCEEEEEECCCCHHHH
KAVRMHYEDVLDNPAEWARKCVKKFGADLVTLHLISTDPLLDDTPASEAVKVLEDVLQAV
HHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
KCPIIVGGSGNKEKDPEVLEKAAEVAEGERIMLASATLDMDWERIANAAKKYGHVVLSWT
CCCEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEE
QMDINNQKTLNRYLLKRVEMPRDSIVMDPTTAALGYGLDYAFTNMERIRISGLKGDTDLN
EECCCCHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCCHHHHCCCEEEEEECCCCCCCCC
FPISSGTTNAWGAREAWMVDSPIEEDTPWGPRELRGPIWEIITGLTLSLAGVDLFMMMHP
CCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
VAVAVLKEVFNTLGGKVSGGVADPGEWIFMEV
HHHHHHHHHHHHHCCEECCCCCCCCCEEEEEC
>Mature Secondary Structure
MKKFTLEEFLDLLKKYNVEEIEGVKIEGDLEIEFEGSSIDLSAIAPLYSMLSEFGNFLYH
CCCCCHHHHHHHHHHCCCCHHCCEEEECCEEEEECCCEECHHHHHHHHHHHHHHHHHHHH
ANMALGYLQRLSAALGIPTPFAAQPQLAPAAPAAPAEVPAVEELKIPAELVRAKFEPYKE
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHCCCHHH
EYPGKIEEVVLGATKADGGTREYTVTLGGERSLAFYTFDAPQPHLPAIAIDVFDRRPMLA
HCCCHHHHHEEECCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCEEEEEECCCCHHHH
KAVRMHYEDVLDNPAEWARKCVKKFGADLVTLHLISTDPLLDDTPASEAVKVLEDVLQAV
HHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
KCPIIVGGSGNKEKDPEVLEKAAEVAEGERIMLASATLDMDWERIANAAKKYGHVVLSWT
CCCEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEE
QMDINNQKTLNRYLLKRVEMPRDSIVMDPTTAALGYGLDYAFTNMERIRISGLKGDTDLN
EECCCCHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCCHHHHCCCEEEEEECCCCCCCCC
FPISSGTTNAWGAREAWMVDSPIEEDTPWGPRELRGPIWEIITGLTLSLAGVDLFMMMHP
CCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
VAVAVLKEVFNTLGGKVSGGVADPGEWIFMEV
HHHHHHHHHHHHHCCEECCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CO; H2O; A

Specific reaction: CO + H2O + A = CO2 + AH2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475; 9575239