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The map label for this gene is hpyA1-1

Identifier: 11497949

GI number: 11497949

Start: 308265

End: 308483

Strand: Reverse

Name: hpyA1-1

Synonym: AF0337

Alternate gene names: 11497949

Gene position: 308483-308265 (Counterclockwise)

Preceding gene: 11497950

Following gene: 11497944

Centisome position: 14.16

GC content: 50.23

Gene sequence:

>219_bases
ATGGAGGTGTTAAGGGTGGAGCTTCCACTTGCTCCTGTGGAAAGGCTTCTGAGAAAGGCTGGAGCTTCAAGGGTCAGTGA
GGATGCAAAGGTGGAACTGGCGAAGGCCATAGAAGAATACGCCATGCAAATTGGCAAAAAGGCTGCTGAGCTGGCAAAAC
ATGCTGGGAGAAAGACGGTAAAGGTGGATGACATCAAGCTTGCTCTGAGGGAGCTTTAA

Upstream 100 bases:

>100_bases
CAGATTCCCAATACGATATTTTTGCCTCCTGAAAAGTCCATTTCATGAAAAAATTTATATAGGATTTTGGCACATTAATC
ATTGGTTAGTCTGAACCAGA

Downstream 100 bases:

>100_bases
AACCTTCAACTTTTCGATTTACATTTTTTATAATAAATTAAGGGATGCGAAACCCTGCAATCGGCAACGCAGTTGCTGTA
GGTTCTCATTGTGTCGCACG

Product: histone A1 (hpyA1-1)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 72; Mature: 72

Protein sequence:

>72_residues
MEVLRVELPLAPVERLLRKAGASRVSEDAKVELAKAIEEYAMQIGKKAAELAKHAGRKTVKVDDIKLALREL

Sequences:

>Translated_72_residues
MEVLRVELPLAPVERLLRKAGASRVSEDAKVELAKAIEEYAMQIGKKAAELAKHAGRKTVKVDDIKLALREL
>Mature_72_residues
MEVLRVELPLAPVERLLRKAGASRVSEDAKVELAKAIEEYAMQIGKKAAELAKHAGRKTVKVDDIKLALREL

Specific function: Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation

COG id: COG2036

COG function: function code B; Histones H3 and H4

Gene ontology:

Cell location: Cytoplasm (Potential). Chromosome (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal histone HMF family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HAF1_ARCFU (O29910)

Other databases:

- EMBL:   AE000782
- PIR:   A69292
- RefSeq:   NP_069173.1
- ProteinModelPortal:   O29910
- SMR:   O29910
- GeneID:   1483551
- GenomeReviews:   AE000782_GR
- KEGG:   afu:AF0337
- NMPDR:   fig|224325.1.peg.332
- TIGR:   AF_0337
- HOGENOM:   HBG392052
- OMA:   IRTAGAH
- ProtClustDB:   CLSK2746383
- BioCyc:   AFUL224325:AF_0337-MONOMER
- GO:   GO:0005694
- GO:   GO:0005737
- InterPro:   IPR003958
- InterPro:   IPR009072
- Gene3D:   G3DSA:1.10.20.10

Pfam domain/function: PF00808 CBFD_NFYB_HMF; SSF47113 Histone-fold

EC number: NA

Molecular weight: Translated: 7966; Mature: 7966

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVLRVELPLAPVERLLRKAGASRVSEDAKVELAKAIEEYAMQIGKKAAELAKHAGRKTV
CCCEEEECCHHHHHHHHHHHCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KVDDIKLALREL
CHHHHHHHHHCC
>Mature Secondary Structure
MEVLRVELPLAPVERLLRKAGASRVSEDAKVELAKAIEEYAMQIGKKAAELAKHAGRKTV
CCCEEEECCHHHHHHHHHHHCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KVDDIKLALREL
CHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475