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The map label for this gene is napA-1

Identifier: 11497833

GI number: 11497833

Start: 193282

End: 194415

Strand: Reverse

Name: napA-1

Synonym: AF0217

Alternate gene names: 11497833

Gene position: 194415-193282 (Counterclockwise)

Preceding gene: 11497834

Following gene: 11497829

Centisome position: 8.92

GC content: 49.12

Gene sequence:

>1134_bases
GTGAGTGAGGTAGAGCAGTTCGCCACCATCGCTTTAATCTCCCTAACCGCCTTCATTTCCCCTTTAATCGCAGACAAGCT
AAGGGTTCCGGTAGTTGTTCTTGAGATCGTGCTCGGCATGATTTTCGGTGTTAGCTTCCTTAACGTAATCTACGCTTCCG
AATGGCTTTCATTTCTCTCACTTTTCGGCCTCATTTTTCTCATGTTCCTTGCCGGGCTTGAGATTGACGCAGATGTGGTT
TTGAAGAGCGGCCATTTAAAGAGGGTTGTAGCGTTCTTCGCCCTCTCACTCGCTCTCAGCGTCGCGTTAACAGCTCTAAT
GGGATTAAACCTCTTTTACGCTATCATCCTTACAAACGTGGCGGTGGGTGTTGTAGTCTCTGTGCTGAGGGAAATTGGAC
TGGAAAAGGAGGATTTCGGGCAGCTGAACATAGTAACCGCTCTGGTTTCCGATTTCTCTACGATGTTTCTGCTTTCCATT
TACTTCATAACTGGCTACCTGCAGGTAGCCTTTGCCTTCCTGATAATTCTTGTTTTCCTCGCAGCCTACCGCTTCGGTAA
GCTGGTGATATGGCACTTTCCTGACTTCATATCGAGGTGGTTCTCGGATGAGCCTTCTGAAATCGGAGTGAGGGGGAGCC
TGGCCATCATGATTCTCTTCGTTGGCCTGAGCTCCCTCCTCGGAGTTGAGGCAATTCTGGGAGCTTTCCTTGCGGGAGTT
CTGCTTTCGATAACCTTCAGGGGCGGAAAGAAGCTCTACGACAAGCTCTACGGTATGGGTTTTGGATTCTTCATCCCCAT
CTTCTTCATCAAAACGGGTAGTGAGCTCAATATCACGCAGGCCGGAGAGGGGATTGGTTTCATTCTCCTTCTGCTTGCCG
TATCTGTTGCAGTTAAGGGAATTCCATCCCTGATTTTTGCCTCAAACTTCGGTTTGAGAAGGGCGATTTCGATGGGTATG
CTTCAGTCCACGAAGCTGAGCCTTACAATCGCCGGTGTGGCAATCGGAGTCTCCTCAGGAGTTATTACCGAGTTCGAGAG
CACCGCATTGGTGACATTCACTATAATATCGTGCCTGCTTTCCCCAACGCTTTTCCGCTTCCTCTATCCCAGATACCTTC
CAAAAACGAGGTAG

Upstream 100 bases:

>100_bases
ACCTCGTCATTCTCTCCCTCTCCAATGACATCGGGAACATTGACAGAGACATTCTCTGGAAAATAATTCTCGACAAGGAG
TCTTCCGTTCTGGTGGTAGA

Downstream 100 bases:

>100_bases
CCTGTGTGCCAGACCTTCGTTGAGGTTCTCGTCCCAACTCTTTTGATGTCTAGGTCCACTCTAAGCAACTCGAACGCTTC
GAGCTCCTTGAATCCGCGCC

Product: Na+/H+ antiporter (napA-1)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MSEVEQFATIALISLTAFISPLIADKLRVPVVVLEIVLGMIFGVSFLNVIYASEWLSFLSLFGLIFLMFLAGLEIDADVV
LKSGHLKRVVAFFALSLALSVALTALMGLNLFYAIILTNVAVGVVVSVLREIGLEKEDFGQLNIVTALVSDFSTMFLLSI
YFITGYLQVAFAFLIILVFLAAYRFGKLVIWHFPDFISRWFSDEPSEIGVRGSLAIMILFVGLSSLLGVEAILGAFLAGV
LLSITFRGGKKLYDKLYGMGFGFFIPIFFIKTGSELNITQAGEGIGFILLLLAVSVAVKGIPSLIFASNFGLRRAISMGM
LQSTKLSLTIAGVAIGVSSGVITEFESTALVTFTIISCLLSPTLFRFLYPRYLPKTR

Sequences:

>Translated_377_residues
MSEVEQFATIALISLTAFISPLIADKLRVPVVVLEIVLGMIFGVSFLNVIYASEWLSFLSLFGLIFLMFLAGLEIDADVV
LKSGHLKRVVAFFALSLALSVALTALMGLNLFYAIILTNVAVGVVVSVLREIGLEKEDFGQLNIVTALVSDFSTMFLLSI
YFITGYLQVAFAFLIILVFLAAYRFGKLVIWHFPDFISRWFSDEPSEIGVRGSLAIMILFVGLSSLLGVEAILGAFLAGV
LLSITFRGGKKLYDKLYGMGFGFFIPIFFIKTGSELNITQAGEGIGFILLLLAVSVAVKGIPSLIFASNFGLRRAISMGM
LQSTKLSLTIAGVAIGVSSGVITEFESTALVTFTIISCLLSPTLFRFLYPRYLPKTR
>Mature_376_residues
SEVEQFATIALISLTAFISPLIADKLRVPVVVLEIVLGMIFGVSFLNVIYASEWLSFLSLFGLIFLMFLAGLEIDADVVL
KSGHLKRVVAFFALSLALSVALTALMGLNLFYAIILTNVAVGVVVSVLREIGLEKEDFGQLNIVTALVSDFSTMFLLSIY
FITGYLQVAFAFLIILVFLAAYRFGKLVIWHFPDFISRWFSDEPSEIGVRGSLAIMILFVGLSSLLGVEAILGAFLAGVL
LSITFRGGKKLYDKLYGMGFGFFIPIFFIKTGSELNITQAGEGIGFILLLLAVSVAVKGIPSLIFASNFGLRRAISMGML
QSTKLSLTIAGVAIGVSSGVITEFESTALVTFTIISCLLSPTLFRFLYPRYLPKTR

Specific function: Probable Na(+)/H(+) antiporter [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322367, Length=388, Percent_Identity=23.9690721649485, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 41027; Mature: 40896

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVEQFATIALISLTAFISPLIADKLRVPVVVLEIVLGMIFGVSFLNVIYASEWLSFLS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFGLIFLMFLAGLEIDADVVLKSGHLKRVVAFFALSLALSVALTALMGLNLFYAIILTNV
HHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGVVVSVLREIGLEKEDFGQLNIVTALVSDFSTMFLLSIYFITGYLQVAFAFLIILVFL
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAYRFGKLVIWHFPDFISRWFSDEPSEIGVRGSLAIMILFVGLSSLLGVEAILGAFLAGV
HHHHHCCEEEEECHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSITFRGGKKLYDKLYGMGFGFFIPIFFIKTGSELNITQAGEGIGFILLLLAVSVAVKG
HHHHHHCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHC
IPSLIFASNFGLRRAISMGMLQSTKLSLTIAGVAIGVSSGVITEFESTALVTFTIISCLL
CHHHHHHCCCCHHHHHHHHHHHHCHHEEEEHHHHHHCCCCCHHHHCCHHHHHHHHHHHHH
SPTLFRFLYPRYLPKTR
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SEVEQFATIALISLTAFISPLIADKLRVPVVVLEIVLGMIFGVSFLNVIYASEWLSFLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFGLIFLMFLAGLEIDADVVLKSGHLKRVVAFFALSLALSVALTALMGLNLFYAIILTNV
HHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGVVVSVLREIGLEKEDFGQLNIVTALVSDFSTMFLLSIYFITGYLQVAFAFLIILVFL
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAYRFGKLVIWHFPDFISRWFSDEPSEIGVRGSLAIMILFVGLSSLLGVEAILGAFLAGV
HHHHHCCEEEEECHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSITFRGGKKLYDKLYGMGFGFFIPIFFIKTGSELNITQAGEGIGFILLLLAVSVAVKG
HHHHHHCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHC
IPSLIFASNFGLRRAISMGMLQSTKLSLTIAGVAIGVSSGVITEFESTALVTFTIISCLL
CHHHHHHCCCCHHHHHHHHHHHHCHHEEEEHHHHHHCCCCCHHHHCCHHHHHHHHHHHHH
SPTLFRFLYPRYLPKTR
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]