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The map label for this gene is yfhM [H]

Identifier: 114800471

GI number: 114800471

Start: 2911879

End: 2912862

Strand: Direct

Name: yfhM [H]

Synonym: HNE_2751

Alternate gene names: 114800471

Gene position: 2911879-2912862 (Clockwise)

Preceding gene: 114799657

Following gene: 114800515

Centisome position: 78.59

GC content: 63.31

Gene sequence:

>984_bases
ATGCCGGAATTCCGGATGATTGATGCGGGCGAAGCGAAGATCCGGGTGGCGTTGGAAGGCTCAGGCCCGCTGGCCCTGAT
GGTGCATGGCTTTCCCGAGAGCTGGTATTCCTGGCGCCACCAGATTGGCCCTATAGCGGCGGCGGGCTTCACCGCGGCGG
CGATGGATGTGCGCGGCTATGGCGGCTCTTCCAAGTTCGATGGCGTGCCCGATTTCCGCATGGAAGCGCTGATCGGCGAT
ATTTTGGGCGTCGGCGCAGCGCTTTCCCCGGACTCGCCCTTTGTGCTGATCGGGCATGATTGGGGCGCGCCGCAGGTGTG
GAACACCTCGCTGATCCATCCCGATCGGATCGCCGCGGTGGCGGCGATGTCGGTGCCCTATTTCGGGGTGCCGCAGGTGT
CGTTTGATCTGGTGATCAAGCAGGTGTGGGACGACAAGAACAAGTTCTTCTACCAGTCCTATTTCCGGGAGCCGGGCCGC
GCAGAGGCCGCTTTCGAGGCCGAGCCGCGCCGGTTCCTGAAGGGCTTCTACCATTCGATTTCCGGCGAAGCGAAGACGGG
CGATTTCCCTGTTGGCCAGCCATCGGACTTCCCGCTGCTCGAGGGCCTGAACCCGCCCGAGACGATCGGCGCCTGGATGA
GCGAAGAGGACCTTGATTACTATACCAGCGAATTCACGGCGTCGGGCTTCTTCGGTCCGCTCTCGCGCTATCGCAACCAT
ACGCGCGACTGGGAATTCCTGCTGCCCTACAAGGACCGGAAGATCGAGCAGCCGGCCTGTTTCATTGCCGGCGACAAGGA
CCCGGCCTATTCCGGCTTTGGCATGATCGAGGACCCGATTGGCCGCATGCGGAGCGTTGTGCCCAATCTGGAAACGGCGC
TTGTGCTGCCCGGCTGTGGCCACTGGACCCAGCAGGAACGCCCGGCGGAAGTGAACGCGGCGCTGATCCCCTGGCTGACA
TCGCTGAAAGGCCGCGCTCTCTAG

Upstream 100 bases:

>100_bases
GCGCTGAATCCCTCTCTGGCAAGGGGTGACGCGAGGGTGATGCTTGCCAGACCCGCGCCCCTGACGCAGCTTTGCCGGCA
AAGAACCAGGAGGGTAAGCG

Downstream 100 bases:

>100_bases
AGACGGGCTTGCACAAGTTCAAAAGATATACCAAAGTCTGCAAAGGATATATCAAAGCCCCTGGCCTGCTTGCGTAAGCC
GGGGGGCTCAACTTGCTGCA

Product: putative epoxide hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MPEFRMIDAGEAKIRVALEGSGPLALMVHGFPESWYSWRHQIGPIAAAGFTAAAMDVRGYGGSSKFDGVPDFRMEALIGD
ILGVGAALSPDSPFVLIGHDWGAPQVWNTSLIHPDRIAAVAAMSVPYFGVPQVSFDLVIKQVWDDKNKFFYQSYFREPGR
AEAAFEAEPRRFLKGFYHSISGEAKTGDFPVGQPSDFPLLEGLNPPETIGAWMSEEDLDYYTSEFTASGFFGPLSRYRNH
TRDWEFLLPYKDRKIEQPACFIAGDKDPAYSGFGMIEDPIGRMRSVVPNLETALVLPGCGHWTQQERPAEVNAALIPWLT
SLKGRAL

Sequences:

>Translated_327_residues
MPEFRMIDAGEAKIRVALEGSGPLALMVHGFPESWYSWRHQIGPIAAAGFTAAAMDVRGYGGSSKFDGVPDFRMEALIGD
ILGVGAALSPDSPFVLIGHDWGAPQVWNTSLIHPDRIAAVAAMSVPYFGVPQVSFDLVIKQVWDDKNKFFYQSYFREPGR
AEAAFEAEPRRFLKGFYHSISGEAKTGDFPVGQPSDFPLLEGLNPPETIGAWMSEEDLDYYTSEFTASGFFGPLSRYRNH
TRDWEFLLPYKDRKIEQPACFIAGDKDPAYSGFGMIEDPIGRMRSVVPNLETALVLPGCGHWTQQERPAEVNAALIPWLT
SLKGRAL
>Mature_326_residues
PEFRMIDAGEAKIRVALEGSGPLALMVHGFPESWYSWRHQIGPIAAAGFTAAAMDVRGYGGSSKFDGVPDFRMEALIGDI
LGVGAALSPDSPFVLIGHDWGAPQVWNTSLIHPDRIAAVAAMSVPYFGVPQVSFDLVIKQVWDDKNKFFYQSYFREPGRA
EAAFEAEPRRFLKGFYHSISGEAKTGDFPVGQPSDFPLLEGLNPPETIGAWMSEEDLDYYTSEFTASGFFGPLSRYRNHT
RDWEFLLPYKDRKIEQPACFIAGDKDPAYSGFGMIEDPIGRMRSVVPNLETALVLPGCGHWTQQERPAEVNAALIPWLTS
LKGRAL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=305, Percent_Identity=37.3770491803279, Blast_Score=190, Evalue=1e-48,
Organism=Homo sapiens, GI218777840, Length=306, Percent_Identity=28.4313725490196, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI13376164, Length=306, Percent_Identity=28.4313725490196, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI218777837, Length=318, Percent_Identity=28.3018867924528, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17554012, Length=323, Percent_Identity=24.7678018575851, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17562298, Length=318, Percent_Identity=25.7861635220126, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 36203; Mature: 36072

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00133 CARBOXYPEPT_ZN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEFRMIDAGEAKIRVALEGSGPLALMVHGFPESWYSWRHQIGPIAAAGFTAAAMDVRGY
CCCCEEEECCCEEEEEEEECCCCEEEEEECCCHHHHHHHHHCCCCHHCCHHHEEEEEECC
GGSSKFDGVPDFRMEALIGDILGVGAALSPDSPFVLIGHDWGAPQVWNTSLIHPDRIAAV
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHH
AAMSVPYFGVPQVSFDLVIKQVWDDKNKFFYQSYFREPGRAEAAFEAEPRRFLKGFYHSI
HHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
SGEAKTGDFPVGQPSDFPLLEGLNPPETIGAWMSEEDLDYYTSEFTASGFFGPLSRYRNH
CCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHCC
TRDWEFLLPYKDRKIEQPACFIAGDKDPAYSGFGMIEDPIGRMRSVVPNLETALVLPGCG
CCCEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCC
HWTQQERPAEVNAALIPWLTSLKGRAL
CCCCCCCCCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PEFRMIDAGEAKIRVALEGSGPLALMVHGFPESWYSWRHQIGPIAAAGFTAAAMDVRGY
CCCEEEECCCEEEEEEEECCCCEEEEEECCCHHHHHHHHHCCCCHHCCHHHEEEEEECC
GGSSKFDGVPDFRMEALIGDILGVGAALSPDSPFVLIGHDWGAPQVWNTSLIHPDRIAAV
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHH
AAMSVPYFGVPQVSFDLVIKQVWDDKNKFFYQSYFREPGRAEAAFEAEPRRFLKGFYHSI
HHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
SGEAKTGDFPVGQPSDFPLLEGLNPPETIGAWMSEEDLDYYTSEFTASGFFGPLSRYRNH
CCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHCC
TRDWEFLLPYKDRKIEQPACFIAGDKDPAYSGFGMIEDPIGRMRSVVPNLETALVLPGCG
CCCEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCC
HWTQQERPAEVNAALIPWLTSLKGRAL
CCCCCCCCCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]