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The map label for this gene is corA [H]

Identifier: 114800373

GI number: 114800373

Start: 2948987

End: 2949991

Strand: Reverse

Name: corA [H]

Synonym: HNE_2787

Alternate gene names: 114800373

Gene position: 2949991-2948987 (Counterclockwise)

Preceding gene: 114799604

Following gene: 114798807

Centisome position: 79.62

GC content: 59.2

Gene sequence:

>1005_bases
ATGATCCGCACGTTTACCAATTCCGAGCATCGCTTCGTTCTCTCGGGCGAAACGCTCGAGCATCTCGACACGGCGGTCTG
GGTCGACATCCTGCGGCCGAGCAAGGATGAAGAAACCGCGATCGAGCGCGCGCTTGGCATTGATGTGCCCACCATCGAGG
AAATGAGCGAGATTGAAGTCTCCAGCCGTCTCTATACGGAGGAGGGGGCGACGTTCATGACCACGATGATGCTCTCGCAT
ACCGATGGCGACAATGTGCTGCTGTCACCGATCACCTTCATCCTCAAGGGCGAGCAGCTGATAACGGTGCGCTATGCCGA
GCCGCGTTCCATCGATGCGTTCATCGCGCGCTGCCAGAAGGGCGCAACCTATACCGCCGATGGGGTTGTGGCGGGGTTGC
TGGATGGGCTGATCGAGCGGATCGGGGATGTTCTGGAGCGGACGGGGCATGAGCTGGACGCGCTGTCTGACAACATCTTT
GCCATCAAGGCGCCACTTGTGGACGGGGCGGTGGCGGAGAAGGTGTCGAAGCGGAACAAGGCCCGGCCCCGCAACTATCA
GTCCGTCCTCGAACAGATTGGCCGAAAGGGTGACCTTCTCTCGAAGGTGCGTGAGAGCCTGATTTCGTTTCAGCGGTTGC
TGGCATTCGGAACCGAAATTGCCGTCAGCCGCAAGCCGGGCAAGGAGTATGAAGGACGGTTGCGCACGCTGACGCGAGAC
GTGCAATCGCTGAGCGACCACACGAGCTTCCTTACACAGAAGATCAACTTTCTGCTGGATGCCACGCTTGGCATGATCAA
TATCGAGCAGACGGGCATCATCAAGATTTTCTCGGTGGCGGCGGTTGTGTTCCTGCCGCCGACGCTGATTGCCTCGATCT
ACGGAATGAATTTCGAGGTGATGCCGGAGCTGTCCTGGCCGGTGGGGTATCCGTTGGCGCTCTGCCTGATGGTTCTCTCG
GCGGTCGTGCCCTACCAGTTCTTCAAATGGCGGGGCTGGCTGTAA

Upstream 100 bases:

>100_bases
CGGGCGGCTGATCCGGCTGACACCGGCTGAATAAGCCTCACCTGTTGCCAAGTAAGGCGACTTTACGCAGACATGGGCGG
ACCGTTTTCCGGGGCCGCCC

Downstream 100 bases:

>100_bases
CGTGAAGCGCGGGGCAGGCATGAGCCCGCCCCGCATGTCTCGACGTCTCAGGCGGTGACGCGCAGGCCCGCCATGCGGGT
GATGGTCGCTTCGGCGTCGC

Product: magnesium and cobalt transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MIRTFTNSEHRFVLSGETLEHLDTAVWVDILRPSKDEETAIERALGIDVPTIEEMSEIEVSSRLYTEEGATFMTTMMLSH
TDGDNVLLSPITFILKGEQLITVRYAEPRSIDAFIARCQKGATYTADGVVAGLLDGLIERIGDVLERTGHELDALSDNIF
AIKAPLVDGAVAEKVSKRNKARPRNYQSVLEQIGRKGDLLSKVRESLISFQRLLAFGTEIAVSRKPGKEYEGRLRTLTRD
VQSLSDHTSFLTQKINFLLDATLGMINIEQTGIIKIFSVAAVVFLPPTLIASIYGMNFEVMPELSWPVGYPLALCLMVLS
AVVPYQFFKWRGWL

Sequences:

>Translated_334_residues
MIRTFTNSEHRFVLSGETLEHLDTAVWVDILRPSKDEETAIERALGIDVPTIEEMSEIEVSSRLYTEEGATFMTTMMLSH
TDGDNVLLSPITFILKGEQLITVRYAEPRSIDAFIARCQKGATYTADGVVAGLLDGLIERIGDVLERTGHELDALSDNIF
AIKAPLVDGAVAEKVSKRNKARPRNYQSVLEQIGRKGDLLSKVRESLISFQRLLAFGTEIAVSRKPGKEYEGRLRTLTRD
VQSLSDHTSFLTQKINFLLDATLGMINIEQTGIIKIFSVAAVVFLPPTLIASIYGMNFEVMPELSWPVGYPLALCLMVLS
AVVPYQFFKWRGWL
>Mature_334_residues
MIRTFTNSEHRFVLSGETLEHLDTAVWVDILRPSKDEETAIERALGIDVPTIEEMSEIEVSSRLYTEEGATFMTTMMLSH
TDGDNVLLSPITFILKGEQLITVRYAEPRSIDAFIARCQKGATYTADGVVAGLLDGLIERIGDVLERTGHELDALSDNIF
AIKAPLVDGAVAEKVSKRNKARPRNYQSVLEQIGRKGDLLSKVRESLISFQRLLAFGTEIAVSRKPGKEYEGRLRTLTRD
VQSLSDHTSFLTQKINFLLDATLGMINIEQTGIIKIFSVAAVVFLPPTLIASIYGMNFEVMPELSWPVGYPLALCLMVLS
AVVPYQFFKWRGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=340, Percent_Identity=35, Blast_Score=184, Evalue=8e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 37290; Mature: 37290

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRTFTNSEHRFVLSGETLEHLDTAVWVDILRPSKDEETAIERALGIDVPTIEEMSEIEV
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHH
SSRLYTEEGATFMTTMMLSHTDGDNVLLSPITFILKGEQLITVRYAEPRSIDAFIARCQK
HHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHEECCEEEEEEECCCCCHHHHHHHHHC
GATYTADGVVAGLLDGLIERIGDVLERTGHELDALSDNIFAIKAPLVDGAVAEKVSKRNK
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEECCCCCHHHHHHHHHHCC
ARPRNYQSVLEQIGRKGDLLSKVRESLISFQRLLAFGTEIAVSRKPGKEYEGRLRTLTRD
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHHHHHH
VQSLSDHTSFLTQKINFLLDATLGMINIEQTGIIKIFSVAAVVFLPPTLIASIYGMNFEV
HHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHCHHHHHHHHCCCEEE
MPELSWPVGYPLALCLMVLSAVVPYQFFKWRGWL
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIRTFTNSEHRFVLSGETLEHLDTAVWVDILRPSKDEETAIERALGIDVPTIEEMSEIEV
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHH
SSRLYTEEGATFMTTMMLSHTDGDNVLLSPITFILKGEQLITVRYAEPRSIDAFIARCQK
HHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHEECCEEEEEEECCCCCHHHHHHHHHC
GATYTADGVVAGLLDGLIERIGDVLERTGHELDALSDNIFAIKAPLVDGAVAEKVSKRNK
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEECCCCCHHHHHHHHHHCC
ARPRNYQSVLEQIGRKGDLLSKVRESLISFQRLLAFGTEIAVSRKPGKEYEGRLRTLTRD
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHHHHHH
VQSLSDHTSFLTQKINFLLDATLGMINIEQTGIIKIFSVAAVVFLPPTLIASIYGMNFEV
HHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHCHHHHHHHHCCCEEE
MPELSWPVGYPLALCLMVLSAVVPYQFFKWRGWL
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]