Click here to switch to the map view.

The map label for this gene is bcd [H]

Identifier: 114800356

GI number: 114800356

Start: 228064

End: 229284

Strand: Reverse

Name: bcd [H]

Synonym: HNE_0237

Alternate gene names: 114800356

Gene position: 229284-228064 (Counterclockwise)

Preceding gene: 114800069

Following gene: 114797940

Centisome position: 6.19

GC content: 62.33

Gene sequence:

>1221_bases
ATGAACCTCTCCTTCACCCGCGAAGAAGAAGCCTTCCGCCAGGAAGTTCGCACCTTTCTGGACGCGCACCTGACCGACGA
CCTGCGCGCCTACGCAAAGCGCATGACCAGCGTCTATTCGACCAAGCCCATCGGCATGAAGTGGCAGCAAATTCTGGTGA
AGCAGGGCTGGGCCTGCCCCTCCTGGCCCGTCGAATATGGCGGCACGGGCTGGACCCCGGCGCAGCGCTACATCTTTGAT
GTTGAAATGGCCCGCGCGGGCGCCCCGCCGCTCTCACCCATGGGCATCGGCATGTGCGGCCCCGCCCTCATCGGCCACGG
CTCAAAGGAACAGAAGGATTACTACCTGCCCCGCATTCTCTCAGGCGAGGATTTCTGGTGCCAGGGCTATTCAGAGCCCC
ATGCCGGCTCAGACCTCGCCGCGCTGACCATGTCAGCGGTTGATGATGGCGATGCCTTCATCTGCAATGGCTCCAAAATC
TGGACCACCCACGCCCATGAAGCAAACATGATGTTCTGCCTCGTGCGCACCGACAATTCCGGCAAGCTGCAACAGGGCAT
CACCTTCGTCCTGATCGACATGACCGCGCCCGGCGTCAAAGTGGACCCGATCATCATGCTCTCGGGCGAGCATATCCAGA
ATGCCGTCTTCTTCACCGATGTGCGCGTGCCCAAGGCGAATGTGGTCGGCAAGATCAATGAAGGCTGGACGGTCGCCAAA
TACCTGCTCGAATTCGAGCGTGGCGGATCCTCTTATGGCCCCCGCCTGCTCGCCCGCGTGCGCGCCATCCGCGCCACTGC
CGCCGAAGAGGGTCTGCTGGATGCTGGCTTTGCCCGCAAACTCTCCCTCGCCGAGGCAGAGATCATGGCCCTCGAGGCAG
CAGAACTTCAACAGATGGCAGACCTCGCAAAAGGCGGCACGCCCGGCCTCAAGGCCTCGATGATGAAAATCCGCGGCACC
GAGCTCAGCCAGCACCTGACCGAGCTGGCAATTGAACTGGCCGGTGTCTATGTCGCGCCCTTCCAGCCGCAGCACACCTC
CCCCGGCGGGCCGGTTCCTGTCCCGGAGTGTCTCAATCTGTCCCGGAATGTCCCGGTGGTGGGGCCTGAAAGTGCCGTCA
CCGCCTCGGCCAAGTACCTCAATGACCGGGCCGGATCGATCTATGCCGGCTCCAACGAAATCCAGCGCGGCATCCTTTCC
AAGGGGCAGCTAGGTCTCTGA

Upstream 100 bases:

>100_bases
GCATCGGCCTGCCACGCAGCTTTGTCTGGAAATCTGAAACTCAACGCCGCCGCCTTGTTGAGGCCGCACGCACTGCATCC
ATGGCCAAGGAGGCCCCCGC

Downstream 100 bases:

>100_bases
TTTTACTCAGAAACCCCCGCCCGTCTTGAACCCGCCACCGCCCTTCCTTCCCCGGCCCGAAGGGAAGGAGCGGCCGCCGC
TGCGCGATGGCCGGGATGTC

Product: acyl-CoA dehydrogenase family protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MNLSFTREEEAFRQEVRTFLDAHLTDDLRAYAKRMTSVYSTKPIGMKWQQILVKQGWACPSWPVEYGGTGWTPAQRYIFD
VEMARAGAPPLSPMGIGMCGPALIGHGSKEQKDYYLPRILSGEDFWCQGYSEPHAGSDLAALTMSAVDDGDAFICNGSKI
WTTHAHEANMMFCLVRTDNSGKLQQGITFVLIDMTAPGVKVDPIIMLSGEHIQNAVFFTDVRVPKANVVGKINEGWTVAK
YLLEFERGGSSYGPRLLARVRAIRATAAEEGLLDAGFARKLSLAEAEIMALEAAELQQMADLAKGGTPGLKASMMKIRGT
ELSQHLTELAIELAGVYVAPFQPQHTSPGGPVPVPECLNLSRNVPVVGPESAVTASAKYLNDRAGSIYAGSNEIQRGILS
KGQLGL

Sequences:

>Translated_406_residues
MNLSFTREEEAFRQEVRTFLDAHLTDDLRAYAKRMTSVYSTKPIGMKWQQILVKQGWACPSWPVEYGGTGWTPAQRYIFD
VEMARAGAPPLSPMGIGMCGPALIGHGSKEQKDYYLPRILSGEDFWCQGYSEPHAGSDLAALTMSAVDDGDAFICNGSKI
WTTHAHEANMMFCLVRTDNSGKLQQGITFVLIDMTAPGVKVDPIIMLSGEHIQNAVFFTDVRVPKANVVGKINEGWTVAK
YLLEFERGGSSYGPRLLARVRAIRATAAEEGLLDAGFARKLSLAEAEIMALEAAELQQMADLAKGGTPGLKASMMKIRGT
ELSQHLTELAIELAGVYVAPFQPQHTSPGGPVPVPECLNLSRNVPVVGPESAVTASAKYLNDRAGSIYAGSNEIQRGILS
KGQLGL
>Mature_406_residues
MNLSFTREEEAFRQEVRTFLDAHLTDDLRAYAKRMTSVYSTKPIGMKWQQILVKQGWACPSWPVEYGGTGWTPAQRYIFD
VEMARAGAPPLSPMGIGMCGPALIGHGSKEQKDYYLPRILSGEDFWCQGYSEPHAGSDLAALTMSAVDDGDAFICNGSKI
WTTHAHEANMMFCLVRTDNSGKLQQGITFVLIDMTAPGVKVDPIIMLSGEHIQNAVFFTDVRVPKANVVGKINEGWTVAK
YLLEFERGGSSYGPRLLARVRAIRATAAEEGLLDAGFARKLSLAEAEIMALEAAELQQMADLAKGGTPGLKASMMKIRGT
ELSQHLTELAIELAGVYVAPFQPQHTSPGGPVPVPECLNLSRNVPVVGPESAVTASAKYLNDRAGSIYAGSNEIQRGILS
KGQLGL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=257, Percent_Identity=29.9610894941634, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI226958414, Length=214, Percent_Identity=31.7757009345794, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI4501859, Length=420, Percent_Identity=25.4761904761905, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4557233, Length=352, Percent_Identity=26.7045454545455, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI4557235, Length=296, Percent_Identity=28.7162162162162, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI76496475, Length=296, Percent_Identity=28.7162162162162, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI21361497, Length=296, Percent_Identity=26.3513513513513, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4557231, Length=244, Percent_Identity=26.2295081967213, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI187960098, Length=244, Percent_Identity=26.2295081967213, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI7656849, Length=144, Percent_Identity=31.9444444444444, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI211971008, Length=254, Percent_Identity=25.5905511811024, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI48976061, Length=254, Percent_Identity=25.5905511811024, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI4501857, Length=236, Percent_Identity=23.728813559322, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87081958, Length=250, Percent_Identity=24.4, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17538396, Length=256, Percent_Identity=29.6875, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17551932, Length=192, Percent_Identity=32.8125, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17570075, Length=255, Percent_Identity=29.4117647058824, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17505929, Length=181, Percent_Identity=32.5966850828729, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17506239, Length=250, Percent_Identity=31.6, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=187, Percent_Identity=35.2941176470588, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508101, Length=361, Percent_Identity=25.4847645429363, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17534899, Length=194, Percent_Identity=31.9587628865979, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17569725, Length=207, Percent_Identity=30.4347826086957, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71990804, Length=193, Percent_Identity=27.4611398963731, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21355753, Length=249, Percent_Identity=29.3172690763052, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI281363737, Length=296, Percent_Identity=27.3648648648649, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24646207, Length=348, Percent_Identity=25.8620689655172, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21356377, Length=345, Percent_Identity=26.3768115942029, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24660351, Length=147, Percent_Identity=31.9727891156463, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 44040; Mature: 44040

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSFTREEEAFRQEVRTFLDAHLTDDLRAYAKRMTSVYSTKPIGMKWQQILVKQGWACP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
SWPVEYGGTGWTPAQRYIFDVEMARAGAPPLSPMGIGMCGPALIGHGSKEQKDYYLPRIL
CCCCCCCCCCCCCHHHEEEEEEHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCEEE
SGEDFWCQGYSEPHAGSDLAALTMSAVDDGDAFICNGSKIWTTHAHEANMMFCLVRTDNS
CCCCCEECCCCCCCCCCCHHHEEEEECCCCCEEEECCCEEEEEECCCCCEEEEEEEECCC
GKLQQGITFVLIDMTAPGVKVDPIIMLSGEHIQNAVFFTDVRVPKANVVGKINEGWTVAK
CCHHCCCEEEEEEECCCCCEECEEEEECCCHHCCEEEEEEECCCCCCEEEECCCCHHHHH
YLLEFERGGSSYGPRLLARVRAIRATAAEEGLLDAGFARKLSLAEAEIMALEAAELQQMA
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DLAKGGTPGLKASMMKIRGTELSQHLTELAIELAGVYVAPFQPQHTSPGGPVPVPECLNL
HHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCHHHHCC
SRNVPVVGPESAVTASAKYLNDRAGSIYAGSNEIQRGILSKGQLGL
CCCCCCCCCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNLSFTREEEAFRQEVRTFLDAHLTDDLRAYAKRMTSVYSTKPIGMKWQQILVKQGWACP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
SWPVEYGGTGWTPAQRYIFDVEMARAGAPPLSPMGIGMCGPALIGHGSKEQKDYYLPRIL
CCCCCCCCCCCCCHHHEEEEEEHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCEEE
SGEDFWCQGYSEPHAGSDLAALTMSAVDDGDAFICNGSKIWTTHAHEANMMFCLVRTDNS
CCCCCEECCCCCCCCCCCHHHEEEEECCCCCEEEECCCEEEEEECCCCCEEEEEEEECCC
GKLQQGITFVLIDMTAPGVKVDPIIMLSGEHIQNAVFFTDVRVPKANVVGKINEGWTVAK
CCHHCCCEEEEEEECCCCCEECEEEEECCCHHCCEEEEEEECCCCCCEEEECCCCHHHHH
YLLEFERGGSSYGPRLLARVRAIRATAAEEGLLDAGFARKLSLAEAEIMALEAAELQQMA
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DLAKGGTPGLKASMMKIRGTELSQHLTELAIELAGVYVAPFQPQHTSPGGPVPVPECLNL
HHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCHHHHCC
SRNVPVVGPESAVTASAKYLNDRAGSIYAGSNEIQRGILSKGQLGL
CCCCCCCCCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]