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The map label for this gene is phnE [H]

Identifier: 114800354

GI number: 114800354

Start: 2582416

End: 2583438

Strand: Direct

Name: phnE [H]

Synonym: HNE_2461

Alternate gene names: 114800354

Gene position: 2582416-2583438 (Clockwise)

Preceding gene: 114799281

Following gene: 114797479

Centisome position: 69.7

GC content: 52.69

Gene sequence:

>1023_bases
ATGACGGCGATCGCCAACCCGCCGGTTGATCGATTGCCCAATGTCTGGCGCCGAAAGCCAGTATTTGGCGTACGTTCACT
GATCTTTCTGATTGCGGGACTGATATTCATGATCTGGTCTGCTCCGCGCGTGGAGCTAGGTGTTCTGACCGGCAATGCCG
GGGAATTGATTGCGTCCCTGGCGGGCAGGCAGGACACTTCGCAGATCGAACGCGGCCTGACATCTATTTCCGACAAGATG
TTTCCCATTGTTTTAGACGAGCGCACTCTGCTTTCGGCAGATAATATTCCAGGCGACAATAAGCTTCCTGTCTTCGCATA
TGTTGAGCGATCATTTACTCAGGAAACGGCGCTCAATCCCGAAACACTGGAAATTGAAACGCGCCAAATACCTCAAAATG
TCCTTGTACAGCCATTCGGATATGTCTTCTATGTTTGCAGCAAGATGCTTCAATCGATTGAAATGGCCATCTGGGCGAGC
GTGATTGCCATGGTTGCCAGCCTACTGCTGATGCCGTTAGCGGCAATGAATTTTACGCCTCACCCGCTGATCCGCGCTGG
CGTGCGCGCTTTCGTTTCCTTCACACGAACAATTCCTGAGCTTGTCAGCGCTCTGTTTCTCGTCCTTCTGTTTGGCTTTG
GTCCGGTCGCCGGAATTTTGGCTTTGGCTATCCACAGCATTGGATTCCTGGCAAAATTCTATGCCGAGGAAGTAGAGACC
GCCGATATCCGTCCTCAGGAAGCGCTCACTGCACTTGGCGCTGGCCCGCTGACCGTTCTCCGGATTGCGGTTATCCCGAA
TGTGATCCCCTCATTCGTCGCGCTTACACTTTATGTGGTTGACCGCAATATCCGCATGGCAACCGTTATCGGGCTCGTAG
GCGCCGGAGGTATCGGGCAAGAATTGAAGGGCCGCTTCGATATGCTCCAATACGGCCATGTCGGCACGATCCTGCTGATC
ATTTTCATCACGGTTTTAATCCTGGATTTCATTTCGGGAAACCTGCGGCGCCACACTATTTGA

Upstream 100 bases:

>100_bases
TCGTCATGAGAAACGGACGCCCGGTGTTTAATGACTGCCCGGCCGAGTTGTCAGGCTTTCTGGAACGCTCTGCGATCCCC
CCCAAAAGGAGCGGCGCAGC

Downstream 100 bases:

>100_bases
TCTGGCCCCTTTCGCTTGCCAAACCGCGCCAGGTTTCATCGCCCGGCGGGTGGCCCCTATTTGACATCGCGTTCCGTGGC
ACGGGACAATGCAAATCCTG

Product: phosphonate ABC transporter permease

Products: 3-phospho-serine [Cytoplasm]; phosphite [Cytoplasm]; ADP; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTAIANPPVDRLPNVWRRKPVFGVRSLIFLIAGLIFMIWSAPRVELGVLTGNAGELIASLAGRQDTSQIERGLTSISDKM
FPIVLDERTLLSADNIPGDNKLPVFAYVERSFTQETALNPETLEIETRQIPQNVLVQPFGYVFYVCSKMLQSIEMAIWAS
VIAMVASLLLMPLAAMNFTPHPLIRAGVRAFVSFTRTIPELVSALFLVLLFGFGPVAGILALAIHSIGFLAKFYAEEVET
ADIRPQEALTALGAGPLTVLRIAVIPNVIPSFVALTLYVVDRNIRMATVIGLVGAGGIGQELKGRFDMLQYGHVGTILLI
IFITVLILDFISGNLRRHTI

Sequences:

>Translated_340_residues
MTAIANPPVDRLPNVWRRKPVFGVRSLIFLIAGLIFMIWSAPRVELGVLTGNAGELIASLAGRQDTSQIERGLTSISDKM
FPIVLDERTLLSADNIPGDNKLPVFAYVERSFTQETALNPETLEIETRQIPQNVLVQPFGYVFYVCSKMLQSIEMAIWAS
VIAMVASLLLMPLAAMNFTPHPLIRAGVRAFVSFTRTIPELVSALFLVLLFGFGPVAGILALAIHSIGFLAKFYAEEVET
ADIRPQEALTALGAGPLTVLRIAVIPNVIPSFVALTLYVVDRNIRMATVIGLVGAGGIGQELKGRFDMLQYGHVGTILLI
IFITVLILDFISGNLRRHTI
>Mature_339_residues
TAIANPPVDRLPNVWRRKPVFGVRSLIFLIAGLIFMIWSAPRVELGVLTGNAGELIASLAGRQDTSQIERGLTSISDKMF
PIVLDERTLLSADNIPGDNKLPVFAYVERSFTQETALNPETLEIETRQIPQNVLVQPFGYVFYVCSKMLQSIEMAIWASV
IAMVASLLLMPLAAMNFTPHPLIRAGVRAFVSFTRTIPELVSALFLVLLFGFGPVAGILALAIHSIGFLAKFYAEEVETA
DIRPQEALTALGAGPLTVLRIAVIPNVIPSFVALTLYVVDRNIRMATVIGLVGAGGIGQELKGRFDMLQYGHVGTILLII
FITVLILDFISGNLRRHTI

Specific function: Probably forms part of a binding-protein-dependent hypophosphite transporter [H]

COG id: COG3639

COG function: function code P; ABC-type phosphate/phosphonate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37155; Mature: 37023

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAIANPPVDRLPNVWRRKPVFGVRSLIFLIAGLIFMIWSAPRVELGVLTGNAGELIASL
CCCCCCCCHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHH
AGRQDTSQIERGLTSISDKMFPIVLDERTLLSADNIPGDNKLPVFAYVERSFTQETALNP
HCCCCHHHHHHHHHHHHHCCCEEEECCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
ETLEIETRQIPQNVLVQPFGYVFYVCSKMLQSIEMAIWASVIAMVASLLLMPLAAMNFTP
CEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HPLIRAGVRAFVSFTRTIPELVSALFLVLLFGFGPVAGILALAIHSIGFLAKFYAEEVET
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ADIRPQEALTALGAGPLTVLRIAVIPNVIPSFVALTLYVVDRNIRMATVIGLVGAGGIGQ
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCH
ELKGRFDMLQYGHVGTILLIIFITVLILDFISGNLRRHTI
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TAIANPPVDRLPNVWRRKPVFGVRSLIFLIAGLIFMIWSAPRVELGVLTGNAGELIASL
CCCCCCCHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHH
AGRQDTSQIERGLTSISDKMFPIVLDERTLLSADNIPGDNKLPVFAYVERSFTQETALNP
HCCCCHHHHHHHHHHHHHCCCEEEECCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
ETLEIETRQIPQNVLVQPFGYVFYVCSKMLQSIEMAIWASVIAMVASLLLMPLAAMNFTP
CEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HPLIRAGVRAFVSFTRTIPELVSALFLVLLFGFGPVAGILALAIHSIGFLAKFYAEEVET
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ADIRPQEALTALGAGPLTVLRIAVIPNVIPSFVALTLYVVDRNIRMATVIGLVGAGGIGQ
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCH
ELKGRFDMLQYGHVGTILLIIFITVLILDFISGNLRRHTI
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]