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The map label for this gene is yjjL [H]

Identifier: 114800311

GI number: 114800311

Start: 3224701

End: 3225987

Strand: Direct

Name: yjjL [H]

Synonym: HNE_3053

Alternate gene names: 114800311

Gene position: 3224701-3225987 (Clockwise)

Preceding gene: 114799036

Following gene: 114797891

Centisome position: 87.04

GC content: 62.86

Gene sequence:

>1287_bases
ATGACAAGTCCCGCCTTGCCTGTGGCCGCGCCCAAGATTTCCGGCCGGGCCTGGATACTTGCCGTCCTGACCCTGACATA
CACCTTCAATCATGTGGACCGGCAGATTCTCGTGATCCTTCTGGAGCCGATCAAGACCGAGCTTGGCCTGCGTGACAGCC
AGCTGGGTATGCTCTCCGGCCTCGCCTTTGCCGCTTTCTACGCGACGCTTGGCATTCCCGTGGCGATGTGGGCCGACCGG
GGCAACCGGCGCAACATCATCGCGCTCGCCCTGGGGCTCTGGTCTGCGATGACAGCGTTCTCCGGCCTCGCTCAGAATTA
CTGGCAACTTCTTCTCGCGCGCATGGGCGTCGGCGTGGGTGAAGCCGGTGGAACCCCGCCGGCGACCTCCATGATCGCAG
ACCTCTATCCGCCGCAGGAACGCGCCACGGCGCTTGGCATATATACGGCCGGGATTGGCCTCGGCATCATGGCCGGCTTC
GCGCTTGGCGGCTACGTTTACGAGCTTTACGGCTGGCGCGTGGCCTTCTTCGTGGCCGGCATCCCCGGATTAATCCTTGC
CCTGATCGTCCGCTTCGGCATCCGCGAACCGGTCCGCGGGCTGGCTGACCAGCGCCAGGATGACAGCCCAGCGCCGTCGC
TGGGGGAAACGCTGAAGTTCATCTTCGGCCAGTCGTCATATCTATGGCTGATGGCGGGCTGCCTTCTGATCTGCATTTCA
GCCAACGCCTTTCTGGTTTTCACGTCCAGCCTGCTTCAGCGCACCTATGATCTCTCTCCCGGCCAGGTCTCCCTGCCCCT
CGGGGTGTTGATCGGCGGGGTGGGCAGCATCGGGGCCATCGTACTGGGCCGGGTGTGCGATACGCTGTCAAAGAAAGACC
TGCGCTGGCGGCCGCTGATTATTGCCCTGTGCGCTGCGGTTGCCCTGCCTTTTGCCTGGATGTTCCTGCGCGCGCCCAGC
GTTGAGCTGGCCTATGCCTGGAACATCGTGCCCAGCTTCATCGGGCTGATCTATGCCAGCGTTGCCTATACGGCTTCGCA
GGAGCTGGTGAAGCTGCGCATGCGCTCCTTTGCATCGGCCTTCATGTTGTTCTGCCTGACGCTGATCGGCATTGGCTGCG
GTCCCTGGATCGCAGGTGAGCTTTCCGACCATTTCCTGCGTGGCGGCGCCGAGCGGCCGCTTGCGCGCGCCCTGGAAGTG
ATCTTGCTGTTCAATGCCGCCAGCATTGTCTGCCTGCTGATGGCGACACGCAAATACAGGTCAGATGCCGAAAGGGCGGC
ACTTTGA

Upstream 100 bases:

>100_bases
GGCTGGCCACGGTGCCGCGGGTGGGCCATGCCCCGATCCTCGACGAGCCCCAGGCCGTTTCCGCTATTTCAGATTTTCTC
AGCCGCCTGGAGACCACGGC

Downstream 100 bases:

>100_bases
ACTGTTCTCGTTCAGCTGCAGGCATTGCCGCGCGGGCTCTTGCGGCCGTCTGCGCCGCCGCTTATCGCTGCTGAAGAAGA
CGGAGTGGGTGATGACATAT

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MTSPALPVAAPKISGRAWILAVLTLTYTFNHVDRQILVILLEPIKTELGLRDSQLGMLSGLAFAAFYATLGIPVAMWADR
GNRRNIIALALGLWSAMTAFSGLAQNYWQLLLARMGVGVGEAGGTPPATSMIADLYPPQERATALGIYTAGIGLGIMAGF
ALGGYVYELYGWRVAFFVAGIPGLILALIVRFGIREPVRGLADQRQDDSPAPSLGETLKFIFGQSSYLWLMAGCLLICIS
ANAFLVFTSSLLQRTYDLSPGQVSLPLGVLIGGVGSIGAIVLGRVCDTLSKKDLRWRPLIIALCAAVALPFAWMFLRAPS
VELAYAWNIVPSFIGLIYASVAYTASQELVKLRMRSFASAFMLFCLTLIGIGCGPWIAGELSDHFLRGGAERPLARALEV
ILLFNAASIVCLLMATRKYRSDAERAAL

Sequences:

>Translated_428_residues
MTSPALPVAAPKISGRAWILAVLTLTYTFNHVDRQILVILLEPIKTELGLRDSQLGMLSGLAFAAFYATLGIPVAMWADR
GNRRNIIALALGLWSAMTAFSGLAQNYWQLLLARMGVGVGEAGGTPPATSMIADLYPPQERATALGIYTAGIGLGIMAGF
ALGGYVYELYGWRVAFFVAGIPGLILALIVRFGIREPVRGLADQRQDDSPAPSLGETLKFIFGQSSYLWLMAGCLLICIS
ANAFLVFTSSLLQRTYDLSPGQVSLPLGVLIGGVGSIGAIVLGRVCDTLSKKDLRWRPLIIALCAAVALPFAWMFLRAPS
VELAYAWNIVPSFIGLIYASVAYTASQELVKLRMRSFASAFMLFCLTLIGIGCGPWIAGELSDHFLRGGAERPLARALEV
ILLFNAASIVCLLMATRKYRSDAERAAL
>Mature_427_residues
TSPALPVAAPKISGRAWILAVLTLTYTFNHVDRQILVILLEPIKTELGLRDSQLGMLSGLAFAAFYATLGIPVAMWADRG
NRRNIIALALGLWSAMTAFSGLAQNYWQLLLARMGVGVGEAGGTPPATSMIADLYPPQERATALGIYTAGIGLGIMAGFA
LGGYVYELYGWRVAFFVAGIPGLILALIVRFGIREPVRGLADQRQDDSPAPSLGETLKFIFGQSSYLWLMAGCLLICISA
NAFLVFTSSLLQRTYDLSPGQVSLPLGVLIGGVGSIGAIVLGRVCDTLSKKDLRWRPLIIALCAAVALPFAWMFLRAPSV
ELAYAWNIVPSFIGLIYASVAYTASQELVKLRMRSFASAFMLFCLTLIGIGCGPWIAGELSDHFLRGGAERPLARALEVI
LLFNAASIVCLLMATRKYRSDAERAAL

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI185136021, Length=399, Percent_Identity=25.5639097744361, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI215490096, Length=413, Percent_Identity=26.1501210653753, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI14042968, Length=413, Percent_Identity=26.1501210653753, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI215490100, Length=398, Percent_Identity=25.3768844221106, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI215490102, Length=197, Percent_Identity=30.9644670050761, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI2367379, Length=275, Percent_Identity=26.9090909090909, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082320, Length=195, Percent_Identity=31.2820512820513, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87082404, Length=185, Percent_Identity=28.6486486486486, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789152, Length=211, Percent_Identity=24.6445497630332, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87082231, Length=191, Percent_Identity=27.2251308900524, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17557872, Length=439, Percent_Identity=23.6902050113895, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17539092, Length=403, Percent_Identity=25.5583126550869, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193209775, Length=442, Percent_Identity=23.5294117647059, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640209, Length=327, Percent_Identity=25.6880733944954, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24654041, Length=403, Percent_Identity=22.5806451612903, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24654037, Length=403, Percent_Identity=22.5806451612903, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17864456, Length=404, Percent_Identity=23.2673267326733, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24654039, Length=404, Percent_Identity=23.2673267326733, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24654044, Length=247, Percent_Identity=23.4817813765182, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46018; Mature: 45887

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPALPVAAPKISGRAWILAVLTLTYTFNHVDRQILVILLEPIKTELGLRDSQLGMLSG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LAFAAFYATLGIPVAMWADRGNRRNIIALALGLWSAMTAFSGLAQNYWQLLLARMGVGVG
HHHHHHHHHHCCHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EAGGTPPATSMIADLYPPQERATALGIYTAGIGLGIMAGFALGGYVYELYGWRVAFFVAG
CCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPGLILALIVRFGIREPVRGLADQRQDDSPAPSLGETLKFIFGQSSYLWLMAGCLLICIS
HHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHC
ANAFLVFTSSLLQRTYDLSPGQVSLPLGVLIGGVGSIGAIVLGRVCDTLSKKDLRWRPLI
CCHHHHHHHHHHHHHHCCCCCCEECCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHH
IALCAAVALPFAWMFLRAPSVELAYAWNIVPSFIGLIYASVAYTASQELVKLRMRSFASA
HHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMLFCLTLIGIGCGPWIAGELSDHFLRGGAERPLARALEVILLFNAASIVCLLMATRKYR
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDAERAAL
CCHHHHCC
>Mature Secondary Structure 
TSPALPVAAPKISGRAWILAVLTLTYTFNHVDRQILVILLEPIKTELGLRDSQLGMLSG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LAFAAFYATLGIPVAMWADRGNRRNIIALALGLWSAMTAFSGLAQNYWQLLLARMGVGVG
HHHHHHHHHHCCHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EAGGTPPATSMIADLYPPQERATALGIYTAGIGLGIMAGFALGGYVYELYGWRVAFFVAG
CCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPGLILALIVRFGIREPVRGLADQRQDDSPAPSLGETLKFIFGQSSYLWLMAGCLLICIS
HHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHC
ANAFLVFTSSLLQRTYDLSPGQVSLPLGVLIGGVGSIGAIVLGRVCDTLSKKDLRWRPLI
CCHHHHHHHHHHHHHHCCCCCCEECCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHH
IALCAAVALPFAWMFLRAPSVELAYAWNIVPSFIGLIYASVAYTASQELVKLRMRSFASA
HHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMLFCLTLIGIGCGPWIAGELSDHFLRGGAERPLARALEVILLFNAASIVCLLMATRKYR
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDAERAAL
CCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]