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The map label for this gene is mdtA [H]

Identifier: 114800257

GI number: 114800257

Start: 2191076

End: 2192266

Strand: Reverse

Name: mdtA [H]

Synonym: HNE_2112

Alternate gene names: 114800257

Gene position: 2192266-2191076 (Counterclockwise)

Preceding gene: 114800097

Following gene: 114799636

Centisome position: 59.17

GC content: 65.24

Gene sequence:

>1191_bases
ATGCGTTCGCGCAATTTTGCAACCGTTTCCGTTCTGGCAACGGCTCTTGTCGTCGGGGCATGCAGTGCGCCGCAGGCTCA
AGAGCAGGGCGGTCCTCCCCCGCCGCAGGTCGATGTCGCAGTCCCACTCTCCTCCCAGGTGGCTGACTGGAACGGCTATA
CCGGCCGTTTCGAGTCCGTGGAACGCGTAGAAGTACGTGCCCGCGTCAGCGGCTATGTGAAGTCGGTCAACTTTGAAGAC
GGCGCCCGTGTAAAGGCGGGCGAACTCCTCTTCACGCTCGATGATCGCCCCTTCCGCGCCGCGCTCGCCCAGGCCGAAGC
CCAGCTCGCCCAGGCGAAAGCCCAGAGCGTCCAGGCTCAGTCCGATCTTGAACGGTCCACAAAGCTTGCTGAATCCGGCG
CTGTCTCGGTCGAAGAACTCGAGCAGAACCGCACAGCGCTCGCCAGCGCCGAAGCTGCCGTCGCTGCGGCCGAGGCCGGT
GTCGACGCCGCCCGGCTCGATCTCAGCTTCACCCGTGTCACTGCCCCCATCGACGGCCGGGTCTCTGCCCGTAACGTAGA
CCCCGGCAACCTCGTCGCGGGCGGCAACTCTTCGGGCGACATCCTCACCACGCTGGTGCGCGATGAAGAACTCTACTTCA
CCTTCAACGTCTCCGAGGCCGACTATCTGCGTTATGCCCGCGCCGAGAAGTCAGACGGCGCCGTCAAAGCTGAAGCCCGC
CTTCAGGACGAAACCTCCTTCACCCGTCCGGGCGAGGTGGTCTTCGCCGACAACCGCATGGGCGACACGACCGGTTCGAT
CCGTGTCCGTGCGCTGATCGACAATGAAGACGGCCTCATCCGCCCCGGCATGACCGGTGAAGTCCGCATCAACGGCTCGG
CCCCGTATTCAGCCCTTATGGTGCCCCAGACGGCGGTGCAGACAGACGGCACCCGCCGCACGCTGTTCCTCGTCAACGAG
CGTAACGAAGTTGAGGCCGCCCCGGTCCAGCTCGGCCCGCTCAGTGGCAACATGCAGGTCATCAGCGGCGGCCTTGAGGC
GAATGACCGGGTCGTGGTCAACGGCCTCCTGCGCGCCCGTCCCGGCGCGGTGGTCAACCCCGTTGCGGTCGAGCTTGATT
ACGAAACCGCGCCTGAAGATCCGGCACAGGTCCTCAGCCGTCCAGCCATGTCTGCCCGCCGCGTGAATTGA

Upstream 100 bases:

>100_bases
ACCTGTTGACTTAGGCCTGTCCCAACGTCATATGCGGTCAACAGCTGATGACTTAAAGGCGTTATTCCACCGTTTCGCCT
TGTTTATGAAGGAAAAATGA

Downstream 100 bases:

>100_bases
CACGCGGCGGCCAGCGCCCGCCTGGCCTCCACCCAATCTCTTCCTCCCAGAGACCCATTCTCCCATGCGCCTTTCCCACT
TTTTCATCCGGCGGCCCATC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MRSRNFATVSVLATALVVGACSAPQAQEQGGPPPPQVDVAVPLSSQVADWNGYTGRFESVERVEVRARVSGYVKSVNFED
GARVKAGELLFTLDDRPFRAALAQAEAQLAQAKAQSVQAQSDLERSTKLAESGAVSVEELEQNRTALASAEAAVAAAEAG
VDAARLDLSFTRVTAPIDGRVSARNVDPGNLVAGGNSSGDILTTLVRDEELYFTFNVSEADYLRYARAEKSDGAVKAEAR
LQDETSFTRPGEVVFADNRMGDTTGSIRVRALIDNEDGLIRPGMTGEVRINGSAPYSALMVPQTAVQTDGTRRTLFLVNE
RNEVEAAPVQLGPLSGNMQVISGGLEANDRVVVNGLLRARPGAVVNPVAVELDYETAPEDPAQVLSRPAMSARRVN

Sequences:

>Translated_396_residues
MRSRNFATVSVLATALVVGACSAPQAQEQGGPPPPQVDVAVPLSSQVADWNGYTGRFESVERVEVRARVSGYVKSVNFED
GARVKAGELLFTLDDRPFRAALAQAEAQLAQAKAQSVQAQSDLERSTKLAESGAVSVEELEQNRTALASAEAAVAAAEAG
VDAARLDLSFTRVTAPIDGRVSARNVDPGNLVAGGNSSGDILTTLVRDEELYFTFNVSEADYLRYARAEKSDGAVKAEAR
LQDETSFTRPGEVVFADNRMGDTTGSIRVRALIDNEDGLIRPGMTGEVRINGSAPYSALMVPQTAVQTDGTRRTLFLVNE
RNEVEAAPVQLGPLSGNMQVISGGLEANDRVVVNGLLRARPGAVVNPVAVELDYETAPEDPAQVLSRPAMSARRVN
>Mature_396_residues
MRSRNFATVSVLATALVVGACSAPQAQEQGGPPPPQVDVAVPLSSQVADWNGYTGRFESVERVEVRARVSGYVKSVNFED
GARVKAGELLFTLDDRPFRAALAQAEAQLAQAKAQSVQAQSDLERSTKLAESGAVSVEELEQNRTALASAEAAVAAAEAG
VDAARLDLSFTRVTAPIDGRVSARNVDPGNLVAGGNSSGDILTTLVRDEELYFTFNVSEADYLRYARAEKSDGAVKAEAR
LQDETSFTRPGEVVFADNRMGDTTGSIRVRALIDNEDGLIRPGMTGEVRINGSAPYSALMVPQTAVQTDGTRRTLFLVNE
RNEVEAAPVQLGPLSGNMQVISGGLEANDRVVVNGLLRARPGAVVNPVAVELDYETAPEDPAQVLSRPAMSARRVN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=328, Percent_Identity=33.5365853658537, Blast_Score=175, Evalue=5e-45,
Organism=Escherichia coli, GI1786668, Length=386, Percent_Identity=33.419689119171, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1789665, Length=359, Percent_Identity=30.6406685236769, Blast_Score=151, Evalue=9e-38,
Organism=Escherichia coli, GI1789929, Length=369, Percent_Identity=28.4552845528455, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI87081796, Length=331, Percent_Identity=26.8882175226586, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87081951, Length=185, Percent_Identity=30.2702702702703, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789637, Length=170, Percent_Identity=31.7647058823529, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790519, Length=217, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42056; Mature: 42056

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSRNFATVSVLATALVVGACSAPQAQEQGGPPPPQVDVAVPLSSQVADWNGYTGRFESV
CCCCCEEHHHHHHHHHHHHCCCCCCHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCH
ERVEVRARVSGYVKSVNFEDGARVKAGELLFTLDDRPFRAALAQAEAQLAQAKAQSVQAQ
HHHHHHHHHHHHEEECCCCCCCEEEECEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
SDLERSTKLAESGAVSVEELEQNRTALASAEAAVAAAEAGVDAARLDLSFTRVTAPIDGR
HHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCC
VSARNVDPGNLVAGGNSSGDILTTLVRDEELYFTFNVSEADYLRYARAEKSDGAVKAEAR
EEECCCCCCCEEECCCCCCCEEEEEEECCEEEEEEECCCHHHHHHHHCCCCCCCEEEEEE
LQDETSFTRPGEVVFADNRMGDTTGSIRVRALIDNEDGLIRPGMTGEVRINGSAPYSALM
ECCCCCCCCCCCEEEECCCCCCCCCCEEEEEEEECCCCEECCCCCEEEEECCCCCCEEEE
VPQTAVQTDGTRRTLFLVNERNEVEAAPVQLGPLSGNMQVISGGLEANDRVVVNGLLRAR
CCCHHHCCCCCEEEEEEEECCCCCEECCEEEECCCCCEEEEECCCCCCCEEEEEEHHHCC
PGAVVNPVAVELDYETAPEDPAQVLSRPAMSARRVN
CCCEECCEEEEEECCCCCCCHHHHHHCCCCHHCCCC
>Mature Secondary Structure
MRSRNFATVSVLATALVVGACSAPQAQEQGGPPPPQVDVAVPLSSQVADWNGYTGRFESV
CCCCCEEHHHHHHHHHHHHCCCCCCHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCH
ERVEVRARVSGYVKSVNFEDGARVKAGELLFTLDDRPFRAALAQAEAQLAQAKAQSVQAQ
HHHHHHHHHHHHEEECCCCCCCEEEECEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
SDLERSTKLAESGAVSVEELEQNRTALASAEAAVAAAEAGVDAARLDLSFTRVTAPIDGR
HHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCC
VSARNVDPGNLVAGGNSSGDILTTLVRDEELYFTFNVSEADYLRYARAEKSDGAVKAEAR
EEECCCCCCCEEECCCCCCCEEEEEEECCEEEEEEECCCHHHHHHHHCCCCCCCEEEEEE
LQDETSFTRPGEVVFADNRMGDTTGSIRVRALIDNEDGLIRPGMTGEVRINGSAPYSALM
ECCCCCCCCCCCEEEECCCCCCCCCCEEEEEEEECCCCEECCCCCEEEEECCCCCCEEEE
VPQTAVQTDGTRRTLFLVNERNEVEAAPVQLGPLSGNMQVISGGLEANDRVVVNGLLRAR
CCCHHHCCCCCEEEEEEEECCCCCEECCEEEECCCCCEEEEECCCCCCCEEEEEEHHHCC
PGAVVNPVAVELDYETAPEDPAQVLSRPAMSARRVN
CCCEECCEEEEEECCCCCCCHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA