Click here to switch to the map view.

The map label for this gene is infA

Identifier: 114800246

GI number: 114800246

Start: 1387584

End: 1387802

Strand: Direct

Name: infA

Synonym: HNE_1354

Alternate gene names: 114800246

Gene position: 1387584-1387802 (Clockwise)

Preceding gene: 114799556

Following gene: 114797086

Centisome position: 37.45

GC content: 54.34

Gene sequence:

>219_bases
ATGTCAAAAGAAGAACTGATTGAATTTGAAGGCACAGTCGTCGAACTGCTGCCCAACGCCACGTTCCGGGTAAAGCTCGA
GAACGACCATGAGATCATCGCCCACACCGCCGGCAAGATGCGCAAAAACCGCATCCGCGTGCTCACGGGCGACAAGGTCA
TGGTCGAAATGACCCCTTACGACCTCACCAAGGGCCGTATCACCTACCGCTTCAAGTAA

Upstream 100 bases:

>100_bases
CCTCTCCGCTTGCCGGAATCTGCTGAAACCTGTATGGCGCCCGGCTAGTGATACGTGGAAAAAGCGGCTTTCCTGCCGCA
GCCCCAGATCTGGATAGAGA

Downstream 100 bases:

>100_bases
TCGCCATGCCGGGCAGCGCGCCGCTCATTCTCGCCAGCGCGAGCCCCCGGCGTCTCGAGCTTCTGGCCCAGATCGGCATT
GTGCCGGATCGGGTCGCCCC

Product: translation initiation factor IF-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 72; Mature: 71

Protein sequence:

>72_residues
MSKEELIEFEGTVVELLPNATFRVKLENDHEIIAHTAGKMRKNRIRVLTGDKVMVEMTPYDLTKGRITYRFK

Sequences:

>Translated_72_residues
MSKEELIEFEGTVVELLPNATFRVKLENDHEIIAHTAGKMRKNRIRVLTGDKVMVEMTPYDLTKGRITYRFK
>Mature_71_residues
SKEELIEFEGTVVELLPNATFRVKLENDHEIIAHTAGKMRKNRIRVLTGDKVMVEMTPYDLTKGRITYRFK

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain

Homologues:

Organism=Escherichia coli, GI1787110, Length=70, Percent_Identity=67.1428571428571, Blast_Score=102, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF1_HYPNA (Q0C2H2)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_760071.1
- ProteinModelPortal:   Q0C2H2
- SMR:   Q0C2H2
- STRING:   Q0C2H2
- GeneID:   4287481
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_1354
- NMPDR:   fig|228405.5.peg.1315
- TIGR:   HNE_1354
- eggNOG:   COG0361
- HOGENOM:   HBG286099
- OMA:   VQLDAGH
- ProtClustDB:   PRK00276
- BioCyc:   HNEP81032:HNE_1354-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00075
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00316
- TIGRFAMs:   TIGR00008

Pfam domain/function: PF01176 eIF-1a; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 8410; Mature: 8279

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEELIEFEGTVVELLPNATFRVKLENDHEIIAHTAGKMRKNRIRVLTGDKVMVEMTPY
CCCHHEEEECCEEEEECCCCEEEEEECCCCEEEEECCCCCCCCEEEEEECCEEEEEECCC
DLTKGRITYRFK
CCCCCEEEEEEC
>Mature Secondary Structure 
SKEELIEFEGTVVELLPNATFRVKLENDHEIIAHTAGKMRKNRIRVLTGDKVMVEMTPY
CCHHEEEECCEEEEECCCCEEEEEECCCCEEEEECCCCCCCCEEEEEECCEEEEEECCC
DLTKGRITYRFK
CCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA