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The map label for this gene is hsaB [H]

Identifier: 114800128

GI number: 114800128

Start: 1855670

End: 1856755

Strand: Direct

Name: hsaB [H]

Synonym: HNE_1809

Alternate gene names: 114800128

Gene position: 1855670-1856755 (Clockwise)

Preceding gene: 114797176

Following gene: 114799320

Centisome position: 50.09

GC content: 61.23

Gene sequence:

>1086_bases
ATGGCACAGTTCAGAGGAGTGGGTGGTCTCGCTCTGCAGGGCCAGTTCGCCGGTAATCCGGATGACCCCGCCGTGGTGCT
TCTGGAGCATTCCGGGCAGGGGTCGGGATTCTGGGACGATCTGGCGACCGTGCTGATAAAAGCAGGCAGGCAGGTCATTC
GACTCGCGCCGTTTGATGTGTCCGCCTCGATCATCGCCCGAGATGCAAATACATATACACGGGAAAGCCTTCGCGCCGTC
TTGAGCCAGCTTCCCATGCGACCGGTCATCCTGGCGGCAGCCGACGACGCACCTGCGGCGGCCGGCGCCATAGGTCACGA
CGCGACACTCCTGGCGACAGGCCTCGTTCTGATCGATCCATCCATTCCTGACACTGAAACCCTGGACCATATTCCAGACA
GCCTGCCGGCATTGATAATCGGCGGCGTGCTTGGCGAAAGTTCCAGACGGATCGAGCGCATTGCCCAAAGCATCCCTGGC
GCCGAGGCTGTGGAAATCGGCGGAAACGATAGCCTTTCAGAGGTTGAGTGCTTCGACGCCTTCAGCGCGGTCCTTATCGA
CTTTCTGGAACGGCGCCTTCCGCGCGCAACGCCGGAATATCGCCTTGGGTCAGACGCCCGCACCTTGCGTGACGCCCTTG
GCTGCTTCGCCACCGGCGTTACGATCATGACGGCAAGCGATGCCTCCGGCCAGCCCGTGGGGCTCACGGCGAACTCGTTC
ACGTCTGTCTCCCTTGATCCGCCATTGCTGCTCGCCTGCATCGCCAAAACGGCAGCAAGCTCGGAAGTGTTTCGCGAAGC
CGAGACGTTCGCAGTAAACGTGCTCCATATTGGACAGCAGCCTACCTCAATCCGTTTTTCGCGCCGCGATGAAGATCGCT
TTGGAGCCACGCCGTGGGAACCGGGCCTCAACGGCACGCCAGTGCTGACAGGATCCCTCGCGACGTTCGAGTGCGCACGC
CATGCGGTTCATGACGGCGGGGATCACATCATTCTCATAGGCCAGGTCGAACGCGCACGCTTCGAGCCACGCCGTGATCC
GTTGTTGTATTTCCGCGGCAAGTACCGCCGCCTTCATTTCTCCTGA

Upstream 100 bases:

>100_bases
CCCCTCCATGGGCTGGCCAGCGAGCGCCGCCGCTGTATATGTCTCATATGGCCGGAGCAAATGAGGCATTTGGATTCAAG
GGTTTGGCGATTTGACCAGG

Downstream 100 bases:

>100_bases
GCCTGCGCCAAATCCTTAACAGGATCTGACCGGACGCCTCATCGCGCACCATGCCCGGAAGGGGAAGGGGGTATGCAGGC
AGTTCGCGAGCCAAGGTCGC

Product: flavin reductase family protein

Products: NAD(+); reduced flavin [C]

Alternate protein names: Flavin:NADH reductase [H]

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MAQFRGVGGLALQGQFAGNPDDPAVVLLEHSGQGSGFWDDLATVLIKAGRQVIRLAPFDVSASIIARDANTYTRESLRAV
LSQLPMRPVILAAADDAPAAAGAIGHDATLLATGLVLIDPSIPDTETLDHIPDSLPALIIGGVLGESSRRIERIAQSIPG
AEAVEIGGNDSLSEVECFDAFSAVLIDFLERRLPRATPEYRLGSDARTLRDALGCFATGVTIMTASDASGQPVGLTANSF
TSVSLDPPLLLACIAKTAASSEVFREAETFAVNVLHIGQQPTSIRFSRRDEDRFGATPWEPGLNGTPVLTGSLATFECAR
HAVHDGGDHIILIGQVERARFEPRRDPLLYFRGKYRRLHFS

Sequences:

>Translated_361_residues
MAQFRGVGGLALQGQFAGNPDDPAVVLLEHSGQGSGFWDDLATVLIKAGRQVIRLAPFDVSASIIARDANTYTRESLRAV
LSQLPMRPVILAAADDAPAAAGAIGHDATLLATGLVLIDPSIPDTETLDHIPDSLPALIIGGVLGESSRRIERIAQSIPG
AEAVEIGGNDSLSEVECFDAFSAVLIDFLERRLPRATPEYRLGSDARTLRDALGCFATGVTIMTASDASGQPVGLTANSF
TSVSLDPPLLLACIAKTAASSEVFREAETFAVNVLHIGQQPTSIRFSRRDEDRFGATPWEPGLNGTPVLTGSLATFECAR
HAVHDGGDHIILIGQVERARFEPRRDPLLYFRGKYRRLHFS
>Mature_360_residues
AQFRGVGGLALQGQFAGNPDDPAVVLLEHSGQGSGFWDDLATVLIKAGRQVIRLAPFDVSASIIARDANTYTRESLRAVL
SQLPMRPVILAAADDAPAAAGAIGHDATLLATGLVLIDPSIPDTETLDHIPDSLPALIIGGVLGESSRRIERIAQSIPGA
EAVEIGGNDSLSEVECFDAFSAVLIDFLERRLPRATPEYRLGSDARTLRDALGCFATGVTIMTASDASGQPVGLTANSFT
SVSLDPPLLLACIAKTAASSEVFREAETFAVNVLHIGQQPTSIRFSRRDEDRFGATPWEPGLNGTPVLTGSLATFECARH
AVHDGGDHIILIGQVERARFEPRRDPLLYFRGKYRRLHFS

Specific function: Catalyzes the reduction of free flavins (FMN or FAD) by NADH. Subsequently, the reduced flavins diffuse to the HsaA oxygenase subunit [H]

COG id: COG1853

COG function: function code R; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the non-flavoprotein flavin reductase family [H]

Homologues:

Organism=Escherichia coli, GI87081819, Length=156, Percent_Identity=34.6153846153846, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002563
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF01613 Flavin_Reduct [H]

EC number: 1.6.8.- [C]

Molecular weight: Translated: 38532; Mature: 38401

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQFRGVGGLALQGQFAGNPDDPAVVLLEHSGQGSGFWDDLATVLIKAGRQVIRLAPFDV
CCCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCC
SASIIARDANTYTRESLRAVLSQLPMRPVILAAADDAPAAAGAIGHDATLLATGLVLIDP
CCEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCEEEECC
SIPDTETLDHIPDSLPALIIGGVLGESSRRIERIAQSIPGAEAVEIGGNDSLSEVECFDA
CCCCCHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHH
FSAVLIDFLERRLPRATPEYRLGSDARTLRDALGCFATGVTIMTASDASGQPVGLTANSF
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCCEEEECCCC
TSVSLDPPLLLACIAKTAASSEVFREAETFAVNVLHIGQQPTSIRFSRRDEDRFGATPWE
EEECCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCEEEECCCCCHHCCCCCCC
PGLNGTPVLTGSLATFECARHAVHDGGDHIILIGQVERARFEPRRDPLLYFRGKYRRLHF
CCCCCCCEEECCHHHHHHHHHHHCCCCCEEEEEECCHHHCCCCCCCCEEEEECCCEEECC
S
C
>Mature Secondary Structure 
AQFRGVGGLALQGQFAGNPDDPAVVLLEHSGQGSGFWDDLATVLIKAGRQVIRLAPFDV
CCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCC
SASIIARDANTYTRESLRAVLSQLPMRPVILAAADDAPAAAGAIGHDATLLATGLVLIDP
CCEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCEEEECC
SIPDTETLDHIPDSLPALIIGGVLGESSRRIERIAQSIPGAEAVEIGGNDSLSEVECFDA
CCCCCHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHH
FSAVLIDFLERRLPRATPEYRLGSDARTLRDALGCFATGVTIMTASDASGQPVGLTANSF
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCCEEEECCCC
TSVSLDPPLLLACIAKTAASSEVFREAETFAVNVLHIGQQPTSIRFSRRDEDRFGATPWE
EEECCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCEEEECCCCCHHCCCCCCC
PGLNGTPVLTGSLATFECARHAVHDGGDHIILIGQVERARFEPRRDPLLYFRGKYRRLHF
CCCCCCCEEECCHHHHHHHHHHHCCCCCEEEEEECCHHHCCCCCCCCEEEEECCCEEECC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; flavin [C]

Specific reaction: NADH + flavin = NAD(+) + reduced flavin [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA