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The map label for this gene is katE [H]

Identifier: 114800048

GI number: 114800048

Start: 2592883

End: 2594955

Strand: Direct

Name: katE [H]

Synonym: HNE_2467

Alternate gene names: 114800048

Gene position: 2592883-2594955 (Clockwise)

Preceding gene: 114798985

Following gene: 114798951

Centisome position: 69.98

GC content: 51.42

Gene sequence:

>2073_bases
ATGTCACGACGTTCGATCCAATCGGGCAAAGGAAAAGCCGGAGAGCTGCATCAGACATCATCAGGTCCACGCGATGCTCT
AACGACCAATCATGGAGTTCGGATATCCGATAATCAAAACAGCCTGCGCGCCGGATCGGTGGGGCCGACACTTCTGGAAG
ACTTTGTTCTACGGGAAAAGATCTTCCACTTTGATCATGAGCGCATTCCTGAGCGCATCGTCCACGCACGAGGTAGCGCA
GCACATGGTTATTTTGAATGTACCGATGCGATTCCCGGACTGTCGCGCGCAAGTCTATTTTCTGAAAAAGGAAAGAGGAC
GCCTGTATTTACGCGGTTTTCGACCGTTGCTGGCGGAGCGGGTTCAGTGGACACACCGCGCGATGTGCGTGGATTTGCGG
TGAAATTCTATACTGACGAAGGGAACTGGGATCTCGTTGGAAATAATATTCCGGTGTTTTTCATTCAGGATGCAATCAAA
TTTCCAGACCTTATCCATTCGGTAAAAATGGAAGCTGACAGAGGCTTTCCACAAGCGGCGAGCGCGCACGATACGTTTTG
GGACTTCATCTCGCTGATGCCTGAAACCATGCACACCATGATCTGGGCCATGTCTGATCGCGCGATCCCTCGTTCTTACA
GGATGATGGAAGGATTTGGTGTTCACACTTTCCGGCTGGTGAATGCGAAGGGGAAATCGACTTTTGTGAAGTTCCACTGG
AAGCCAAAGCTTGGCCTGCAATCACTGGTATGGGATGAATCTGCCAAGCTGCAGGGAGCCGACAACGACTTTCACCGCCG
GGACCTTTGGGAGGCGATCGATTCAGGAAATTTTCCGGAATGGAATTTCGGGATTCAGGTAATCTCCGAAAAACTCGCTG
AGGAGCTTCCCTATAATGTGCTCGACCCAACCAAGATCGTGCCCGAGGAAATAGCCCCAGTACGGATCATCGGGCGGATG
GTTCTGGACCGAAACCCCGACAACCACTTTGCTGAAAATGAACAGGCTGCCTTCCTGCCCTCCAATGTCGTTCCTGGAAT
AGATTTCACGAATGATCCCCTTCTTCAAGGCAGACTGTTTTCGTATCTAGACACACAAAAGTCTCGCCTAGGAACAACCA
ATTTCCATCAGATACCCATCAACGCGCCGAAATGCCCATTTGCAAACATGCAGCGCGATGGGATGATGCAGACATTCGTG
CCAAAGGGCCGCGCAAACTATGAGCCGAATACATTGGATGAAGCGGGTGAAGCTGCTGGTCCACGCGCCTCGAAAGAAGG
CTTCCGAACATTCGAGAGCAATACCGAGTTAGGAAACAGCCCAACGGACAAATTAAGGGTGCGGGACGAAACTTTTGGCG
ACCATTTCAGCCAACCCCGCATGTTCTGGCATTCTCAAACCGAAAATGAACAGGCCCATATTGCCTCGGCACTTGTCTTC
GAATTGTCTAAAGTTGGAACTGAACACATCCGCAAGCGCACGCTATCCGTTATTCGGAACATTGATCACGACCTTGCAAA
ACGTGTAGCCGATGGCTTGGGATTGAAAGTGCCAGCTGCGACGCCGCCGTTCAGAGAACCAGTAGACTTGGGATCATCCG
ATTCCCTCTCTATACAGAAGAACTGGCAAACCACGATAAGGGGCCGAACAGTAGCTATCCTCTTTGCGGAAGGATCGGAC
AAGGACGCAATCGATGAATTGACGTCGAGTATTGAAGGCAAGGGTGGCTCGGTATACTTGGTGGCGCCTAAAGTTGGCCC
TCTGAAGGTCAAGGGTGGAATGCTCCAAGCAGATGGCCAGCTTGCAGGCTCACCATCGCCTCTGTTTGATGCTGTCGCAA
TGGTGTTGATGCCGGATCAGGTTGAGAAACTGATGAAAGACTCTGCTGCACGCGGCTGGGTGAGTGACGCATATTCACAT
TTGAAAGCCATTGGGTATTGCCCTGGCTCGAAGGCGCTTCTGGAAGATTGTGGAATTGTGTTTGACGACGGCATCGTGCC
AAATGAAAAATGGGCGAAGGCTGCCGCGCGTCGGTATTGGGATCGTGAATCTAATCTGCGCGATCTGGCTTGA

Upstream 100 bases:

>100_bases
ACGATGCGCCCGGAACCGATGACACTCTGCCGCGTTTATCTGTTCCTGGGGACATTCTTTGAATCCCCCAGGAACTCAAT
CGCAACAAGAGGGTGCAGTT

Downstream 100 bases:

>100_bases
GCCCAAGGGCGCCACTGTAAGGAGGTGCCCGCAATATGGCAAAGCAGAAAGATGATACCCGCAAAGATGATCTGCGAACC
GGTCAACCCTTTTGGCTCAG

Product: catalase HPII

Products: NA

Alternate protein names: KAT2 [H]

Number of amino acids: Translated: 690; Mature: 689

Protein sequence:

>690_residues
MSRRSIQSGKGKAGELHQTSSGPRDALTTNHGVRISDNQNSLRAGSVGPTLLEDFVLREKIFHFDHERIPERIVHARGSA
AHGYFECTDAIPGLSRASLFSEKGKRTPVFTRFSTVAGGAGSVDTPRDVRGFAVKFYTDEGNWDLVGNNIPVFFIQDAIK
FPDLIHSVKMEADRGFPQAASAHDTFWDFISLMPETMHTMIWAMSDRAIPRSYRMMEGFGVHTFRLVNAKGKSTFVKFHW
KPKLGLQSLVWDESAKLQGADNDFHRRDLWEAIDSGNFPEWNFGIQVISEKLAEELPYNVLDPTKIVPEEIAPVRIIGRM
VLDRNPDNHFAENEQAAFLPSNVVPGIDFTNDPLLQGRLFSYLDTQKSRLGTTNFHQIPINAPKCPFANMQRDGMMQTFV
PKGRANYEPNTLDEAGEAAGPRASKEGFRTFESNTELGNSPTDKLRVRDETFGDHFSQPRMFWHSQTENEQAHIASALVF
ELSKVGTEHIRKRTLSVIRNIDHDLAKRVADGLGLKVPAATPPFREPVDLGSSDSLSIQKNWQTTIRGRTVAILFAEGSD
KDAIDELTSSIEGKGGSVYLVAPKVGPLKVKGGMLQADGQLAGSPSPLFDAVAMVLMPDQVEKLMKDSAARGWVSDAYSH
LKAIGYCPGSKALLEDCGIVFDDGIVPNEKWAKAAARRYWDRESNLRDLA

Sequences:

>Translated_690_residues
MSRRSIQSGKGKAGELHQTSSGPRDALTTNHGVRISDNQNSLRAGSVGPTLLEDFVLREKIFHFDHERIPERIVHARGSA
AHGYFECTDAIPGLSRASLFSEKGKRTPVFTRFSTVAGGAGSVDTPRDVRGFAVKFYTDEGNWDLVGNNIPVFFIQDAIK
FPDLIHSVKMEADRGFPQAASAHDTFWDFISLMPETMHTMIWAMSDRAIPRSYRMMEGFGVHTFRLVNAKGKSTFVKFHW
KPKLGLQSLVWDESAKLQGADNDFHRRDLWEAIDSGNFPEWNFGIQVISEKLAEELPYNVLDPTKIVPEEIAPVRIIGRM
VLDRNPDNHFAENEQAAFLPSNVVPGIDFTNDPLLQGRLFSYLDTQKSRLGTTNFHQIPINAPKCPFANMQRDGMMQTFV
PKGRANYEPNTLDEAGEAAGPRASKEGFRTFESNTELGNSPTDKLRVRDETFGDHFSQPRMFWHSQTENEQAHIASALVF
ELSKVGTEHIRKRTLSVIRNIDHDLAKRVADGLGLKVPAATPPFREPVDLGSSDSLSIQKNWQTTIRGRTVAILFAEGSD
KDAIDELTSSIEGKGGSVYLVAPKVGPLKVKGGMLQADGQLAGSPSPLFDAVAMVLMPDQVEKLMKDSAARGWVSDAYSH
LKAIGYCPGSKALLEDCGIVFDDGIVPNEKWAKAAARRYWDRESNLRDLA
>Mature_689_residues
SRRSIQSGKGKAGELHQTSSGPRDALTTNHGVRISDNQNSLRAGSVGPTLLEDFVLREKIFHFDHERIPERIVHARGSAA
HGYFECTDAIPGLSRASLFSEKGKRTPVFTRFSTVAGGAGSVDTPRDVRGFAVKFYTDEGNWDLVGNNIPVFFIQDAIKF
PDLIHSVKMEADRGFPQAASAHDTFWDFISLMPETMHTMIWAMSDRAIPRSYRMMEGFGVHTFRLVNAKGKSTFVKFHWK
PKLGLQSLVWDESAKLQGADNDFHRRDLWEAIDSGNFPEWNFGIQVISEKLAEELPYNVLDPTKIVPEEIAPVRIIGRMV
LDRNPDNHFAENEQAAFLPSNVVPGIDFTNDPLLQGRLFSYLDTQKSRLGTTNFHQIPINAPKCPFANMQRDGMMQTFVP
KGRANYEPNTLDEAGEAAGPRASKEGFRTFESNTELGNSPTDKLRVRDETFGDHFSQPRMFWHSQTENEQAHIASALVFE
LSKVGTEHIRKRTLSVIRNIDHDLAKRVADGLGLKVPAATPPFREPVDLGSSDSLSIQKNWQTTIRGRTVAILFAEGSDK
DAIDELTSSIEGKGGSVYLVAPKVGPLKVKGGMLQADGQLAGSPSPLFDAVAMVLMPDQVEKLMKDSAARGWVSDAYSHL
KAIGYCPGSKALLEDCGIVFDDGIVPNEKWAKAAARRYWDRESNLRDLA

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Could protect cells in nodules which have a high potential to produce hydrogen peroxide because of the strong reducing conditions requ

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family. HPII subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=398, Percent_Identity=48.7437185929648, Blast_Score=375, Evalue=1e-104,
Organism=Escherichia coli, GI48994891, Length=673, Percent_Identity=51.5601783060921, Blast_Score=665, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25151141, Length=448, Percent_Identity=45.0892857142857, Blast_Score=374, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI25147792, Length=449, Percent_Identity=44.7661469933185, Blast_Score=373, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI71998444, Length=443, Percent_Identity=43.3408577878104, Blast_Score=369, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6320462, Length=395, Percent_Identity=44.3037974683544, Blast_Score=322, Evalue=2e-88,
Organism=Saccharomyces cerevisiae, GI6321525, Length=532, Percent_Identity=36.0902255639098, Blast_Score=310, Evalue=5e-85,
Organism=Drosophila melanogaster, GI17981717, Length=494, Percent_Identity=41.2955465587045, Blast_Score=358, Evalue=1e-98,
Organism=Drosophila melanogaster, GI19920968, Length=491, Percent_Identity=39.1038696537678, Blast_Score=353, Evalue=3e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 76615; Mature: 76484

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRSIQSGKGKAGELHQTSSGPRDALTTNHGVRISDNQNSLRAGSVGPTLLEDFVLREK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHH
IFHFDHERIPERIVHARGSAAHGYFECTDAIPGLSRASLFSEKGKRTPVFTRFSTVAGGA
HHHCCHHHHHHHHHHCCCCCCCCCEEEHHCCCCCHHHHHHHHCCCCCCEEEEHHHHCCCC
GSVDTPRDVRGFAVKFYTDEGNWDLVGNNIPVFFIQDAIKFPDLIHSVKMEADRGFPQAA
CCCCCCCCCCEEEEEEEECCCCEEEECCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCC
SAHDTFWDFISLMPETMHTMIWAMSDRAIPRSYRMMEGFGVHTFRLVNAKGKSTFVKFHW
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEEECCCCCEEEEEEE
KPKLGLQSLVWDESAKLQGADNDFHRRDLWEAIDSGNFPEWNFGIQVISEKLAEELPYNV
CCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCC
LDPTKIVPEEIAPVRIIGRMVLDRNPDNHFAENEQAAFLPSNVVPGIDFTNDPLLQGRLF
CCCCCCCHHHCCHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHH
SYLDTQKSRLGTTNFHQIPINAPKCPFANMQRDGMMQTFVPKGRANYEPNTLDEAGEAAG
HHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHCCCCC
PRASKEGFRTFESNTELGNSPTDKLRVRDETFGDHFSQPRMFWHSQTENEQAHIASALVF
CCCCHHHHHHHCCCCCCCCCCCHHEEECCHHHHHCCCCCCEEECCCCCCCHHHHHHHHHH
ELSKVGTEHIRKRTLSVIRNIDHDLAKRVADGLGLKVPAATPPFREPVDLGSSDSLSIQK
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCEEEEC
NWQTTIRGRTVAILFAEGSDKDAIDELTSSIEGKGGSVYLVAPKVGPLKVKGGMLQADGQ
CCHHEECCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCEEEECCC
LAGSPSPLFDAVAMVLMPDQVEKLMKDSAARGWVSDAYSHLKAIGYCPGSKALLEDCGIV
CCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHCCEE
FDDGIVPNEKWAKAAARRYWDRESNLRDLA
EECCCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SRRSIQSGKGKAGELHQTSSGPRDALTTNHGVRISDNQNSLRAGSVGPTLLEDFVLREK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHH
IFHFDHERIPERIVHARGSAAHGYFECTDAIPGLSRASLFSEKGKRTPVFTRFSTVAGGA
HHHCCHHHHHHHHHHCCCCCCCCCEEEHHCCCCCHHHHHHHHCCCCCCEEEEHHHHCCCC
GSVDTPRDVRGFAVKFYTDEGNWDLVGNNIPVFFIQDAIKFPDLIHSVKMEADRGFPQAA
CCCCCCCCCCEEEEEEEECCCCEEEECCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCC
SAHDTFWDFISLMPETMHTMIWAMSDRAIPRSYRMMEGFGVHTFRLVNAKGKSTFVKFHW
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEEECCCCCEEEEEEE
KPKLGLQSLVWDESAKLQGADNDFHRRDLWEAIDSGNFPEWNFGIQVISEKLAEELPYNV
CCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCC
LDPTKIVPEEIAPVRIIGRMVLDRNPDNHFAENEQAAFLPSNVVPGIDFTNDPLLQGRLF
CCCCCCCHHHCCHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHH
SYLDTQKSRLGTTNFHQIPINAPKCPFANMQRDGMMQTFVPKGRANYEPNTLDEAGEAAG
HHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHCCCCC
PRASKEGFRTFESNTELGNSPTDKLRVRDETFGDHFSQPRMFWHSQTENEQAHIASALVF
CCCCHHHHHHHCCCCCCCCCCCHHEEECCHHHHHCCCCCCEEECCCCCCCHHHHHHHHHH
ELSKVGTEHIRKRTLSVIRNIDHDLAKRVADGLGLKVPAATPPFREPVDLGSSDSLSIQK
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCEEEEC
NWQTTIRGRTVAILFAEGSDKDAIDELTSSIEGKGGSVYLVAPKVGPLKVKGGMLQADGQ
CCHHEECCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCEEEECCC
LAGSPSPLFDAVAMVLMPDQVEKLMKDSAARGWVSDAYSHLKAIGYCPGSKALLEDCGIV
CCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHCCEE
FDDGIVPNEKWAKAAARRYWDRESNLRDLA
EECCCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10198032; 11481431 [H]