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The map label for this gene is ycbL [H]

Identifier: 114799929

GI number: 114799929

Start: 652594

End: 653328

Strand: Reverse

Name: ycbL [H]

Synonym: HNE_0649

Alternate gene names: 114799929

Gene position: 653328-652594 (Counterclockwise)

Preceding gene: 114800365

Following gene: 114800337

Centisome position: 17.63

GC content: 63.54

Gene sequence:

>735_bases
ATGACCGAGCAGACCCCCGCCCCGAAACTCGAGATCCGGATCATTCCGGTGACCCCGCTGCAACAGAATACGTCGATGAT
ATGGTCTACCCAGACCATGGAAGGCGTGTTCGTGGACCCCGGCGGGGAGATCGACAAGCTGATGCAGGCGGCCGATCATT
TCGGCGTGAAGATCGTCGCCGTCTGGCTGACGCATGGCCACCTGGACCATGTGGGCGCCGCCATGGCGGTGAAGGATCGC
ACCGGCTGCCCGATCATCGGACCCCACAAGGACGACCAGTGGCTGCTGGACGAAGTGGAAGCCAGCGGCGCCAGGTATGG
CATCCGCGACGGGAAGAATGTGACACCGGACCGGTATCTGGATGATGGCGATGTGCTGGAGCTGGCCGGCAACAAGTTCG
GCGTGGCCCACTGCCCCGGCCATACGCCGGGCCATGTGGTGATCTATCATCCCGAAGGCGCGCTGGCCTTTGTCGGCGAT
GTTCTGTTCCGTGGCTCGGTCGGGCGCACGGATTTCCCGCGCGGCAATCATCAGCAGCTGATCGATTCCATCACCCAGAA
ACTCTGGCCGCTGGGCGATGACATGCGCTTTGTGCCCGGCCACGGCCCCCTCTCCACTTTCGGGCAGGAACGCCAGGACA
ACCCCTTCGTCGCCGACGCCGTGACCGGCTATAATGGCGCCGAAAAAGGCGAAGTGGACCTGATCAGCCAGCGCACCTCC
AAGCGCTGGAGCTGA

Upstream 100 bases:

>100_bases
CTGAAAAGGTGGCTAACAAACCAGTTAACCCAGCGTCTGGCGAGCGAAAAGACAGGACACGCCGCATTGCGCCAAAGGCC
GGGATCGCTATGTTTCCCAC

Downstream 100 bases:

>100_bases
ACCTTACGAAAAATTTGCCGGAACCAACCCCGCGCCGGCACGTTTCCTTCCCATCGGACAGGAAAGGAACGACCCATGAT
TGGATATCTCAAATTTGCCG

Product: metallo-beta-lactamase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MTEQTPAPKLEIRIIPVTPLQQNTSMIWSTQTMEGVFVDPGGEIDKLMQAADHFGVKIVAVWLTHGHLDHVGAAMAVKDR
TGCPIIGPHKDDQWLLDEVEASGARYGIRDGKNVTPDRYLDDGDVLELAGNKFGVAHCPGHTPGHVVIYHPEGALAFVGD
VLFRGSVGRTDFPRGNHQQLIDSITQKLWPLGDDMRFVPGHGPLSTFGQERQDNPFVADAVTGYNGAEKGEVDLISQRTS
KRWS

Sequences:

>Translated_244_residues
MTEQTPAPKLEIRIIPVTPLQQNTSMIWSTQTMEGVFVDPGGEIDKLMQAADHFGVKIVAVWLTHGHLDHVGAAMAVKDR
TGCPIIGPHKDDQWLLDEVEASGARYGIRDGKNVTPDRYLDDGDVLELAGNKFGVAHCPGHTPGHVVIYHPEGALAFVGD
VLFRGSVGRTDFPRGNHQQLIDSITQKLWPLGDDMRFVPGHGPLSTFGQERQDNPFVADAVTGYNGAEKGEVDLISQRTS
KRWS
>Mature_243_residues
TEQTPAPKLEIRIIPVTPLQQNTSMIWSTQTMEGVFVDPGGEIDKLMQAADHFGVKIVAVWLTHGHLDHVGAAMAVKDRT
GCPIIGPHKDDQWLLDEVEASGARYGIRDGKNVTPDRYLDDGDVLELAGNKFGVAHCPGHTPGHVVIYHPEGALAFVGDV
LFRGSVGRTDFPRGNHQQLIDSITQKLWPLGDDMRFVPGHGPLSTFGQERQDNPFVADAVTGYNGAEKGEVDLISQRTSK
RWS

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=198, Percent_Identity=26.7676767676768, Blast_Score=71, Evalue=8e-13,
Organism=Escherichia coli, GI1787158, Length=212, Percent_Identity=49.5283018867925, Blast_Score=226, Evalue=8e-61,
Organism=Caenorhabditis elegans, GI17538952, Length=197, Percent_Identity=28.4263959390863, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221330176, Length=187, Percent_Identity=26.7379679144385, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 26709; Mature: 26578

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQTPAPKLEIRIIPVTPLQQNTSMIWSTQTMEGVFVDPGGEIDKLMQAADHFGVKIVA
CCCCCCCCEEEEEEEECCCCCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHCCEEEEE
VWLTHGHLDHVGAAMAVKDRTGCPIIGPHKDDQWLLDEVEASGARYGIRDGKNVTPDRYL
EEEECCCHHHHCCEEEEECCCCCCEECCCCCCHHHHHHHHCCCCEECCCCCCCCCCCCCC
DDGDVLELAGNKFGVAHCPGHTPGHVVIYHPEGALAFVGDVLFRGSVGRTDFPRGNHQQL
CCCCEEEECCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCHHHH
IDSITQKLWPLGDDMRFVPGHGPLSTFGQERQDNPFVADAVTGYNGAEKGEVDLISQRTS
HHHHHHHHCCCCCCCEEECCCCCHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHH
KRWS
CCCC
>Mature Secondary Structure 
TEQTPAPKLEIRIIPVTPLQQNTSMIWSTQTMEGVFVDPGGEIDKLMQAADHFGVKIVA
CCCCCCCEEEEEEEECCCCCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHCCEEEEE
VWLTHGHLDHVGAAMAVKDRTGCPIIGPHKDDQWLLDEVEASGARYGIRDGKNVTPDRYL
EEEECCCHHHHCCEEEEECCCCCCEECCCCCCHHHHHHHHCCCCEECCCCCCCCCCCCCC
DDGDVLELAGNKFGVAHCPGHTPGHVVIYHPEGALAFVGDVLFRGSVGRTDFPRGNHQQL
CCCCEEEECCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCHHHH
IDSITQKLWPLGDDMRFVPGHGPLSTFGQERQDNPFVADAVTGYNGAEKGEVDLISQRTS
HHHHHHHHCCCCCCCEEECCCCCHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHH
KRWS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]