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The map label for this gene is ppiD [H]

Identifier: 114799881

GI number: 114799881

Start: 1835028

End: 1836941

Strand: Reverse

Name: ppiD [H]

Synonym: HNE_1791

Alternate gene names: 114799881

Gene position: 1836941-1835028 (Counterclockwise)

Preceding gene: 114799922

Following gene: 114799062

Centisome position: 49.58

GC content: 59.51

Gene sequence:

>1914_bases
ATGCTCGCACTTATGAAGAAGATGACCCGTTCCCCGGTGGGGAAGCTGGTTTTGATGATCGTCATCGTCGGAATGGCGTT
CTGGGGCGTCGATGCGATCGTGAATCAGATGCGCAGCGGGCTGGGCGCGAACGTTGTCAGCGCCGGTTCTCGCGGGCTTG
ATCCGGCAGATCTGGATTTTCGGGTGGAAACCGTCCTGCGCAATATCAATGCGACCGCTGAGCGGCCGCTGAGCAAGTCT
GAAGCGCTGGAGCAAGGCCTGATCGACCAGATTGTTGAGGTCGAAAAAGCACGCATAACACGCCTCGGTTACGGTGAAAG
CATTGGTATTTCTCCGTCGCCAGAAGCTGTTGTCGAGGAAATGAACAGCATCCCGGCCTTCCAGAACCCCCTGACCGGTG
AGCTGGACCCCGCGATGTTCCGGGACCGTATTTCTCAGCTGGGCATGTCGCCAGCTCAATTCGAGCGTCAACTGCAGGAC
GACATTCTTATCCGGGCATTGAGCCAGGCAGGTCGATCAGCGGTTTATGGCCCTCAGGTCATTGCAAATATCCAGGCAAA
TTATCTTGGCGAGACGCGGGAGGTTGCATGGTTTTTCTTCGATGCATCAGACGCACCCGCGCCGGAGGTGCCCACCGATG
CCGAGATCAAGGCTTACTATGACGAGCATCTGGAACGGCTGAAACAGCCTGAACGCCGCGCGCTCGACATCCTGCGTATG
TCGACGGATGACTTTACCGGCAAAGTGGAAGTAACTGACCAGGAAGTGGCAACTGTTTACGAAGCCACCAAATCGGAACG
GTTTGCGGCGCCAGATCAACGTACTTACGCGGAGCTCCTGTTCCCGACACGGGACGCTGCGCGCACGGCCTTTGGCCTGC
TTGCCGGCGGCGCCGACCCCAACAGCGTAACAGGTGCGAATTCCGTTCAGATGCGCACGGCGCGCGCCGAAGACATTTCG
GATCAGGCTTTGCAGGACGCCATGTTTGGGCCCGGCAGACAGAGCGGCGCGATGTATGGCCCGCGGGAAGTTGACGGCCA
GTGGCTGGTCGCCCGATTGATTTCGGTCCAGCCCGGCGCAGTGAAACCTCTCGAAGAAGTCGCCGAAGAGATCCGTCTTG
GGCTGGCGCGAGAGCGTGCGCAGCTCCTTTTTTCCGCCGCCCTTGAGACATTGGATGAAGCCCTTGCCGCGGGGAACGAT
CTCTCGCAGGTGGCCGAAGACATCGGCGTTCCAATCATAAGCATCGCACCCGTTGATCAGAACGGAATCACCGAGCAGGG
CAATCAGTTCACAATCCTTTCGGAGGTTCCTGAGGCGCTACCCCAGGCTTTCCGGCTGCCCGAGAACGAAATCGGTAGCC
GCTTTGACGTTGCGAGTTCCGTGGTCCTCGTCGCGCCCCGACGGATTGTTCCGGCTGCTACGCCCGAGCTTGATGCGATC
AAGGACCGGGTAAGCGCGATGATCGTCTCGGAGCGCACTGCCAATGCAGCGGAAGCTGCGGTGGAGGCGCTTACTGAGCG
CGTCCGCGCCGGGTCAGTAACACTCGATGCCGCAGCTGCGGAGAGTGGCGCGCAGGTGGATCGCTTGCCCGAACCGGTAT
CGCGCTCAAACGCTCAGGCTATGGGTGTGCCAGGGCCGCTGATGCAGGCTACATTCAATAACCCGGCTGGCAGCGTCATC
AGTCTGCCGACAGGTGATGGATCTGTATTTGCCATCCTCAAGATCCTGAGTGTTTCCCCGCCAACGCCGGAAATGATTGC
AAGCATGGGCACTGCCGCCTCTGCCGATGTCACAGAGTCGCTCACGGCCGATCTGGAAGCCGCTGTGGATGACGAAATTC
GCCGGGCGGTCAAGGTCAAGGAGAATGCTTCGGCGATCGCCTCTTACAAGCGAACGATAACGGCTGCCCAATGA

Upstream 100 bases:

>100_bases
GCGTGCGTGGCATGCGGCCTTCCCTCTCTTGCAAGTCATAAACCGGTCGCCTAGCAAGCTGTGAGCCACCCGGCAAACCC
CAGAAATAGAGAAGCGCCGT

Downstream 100 bases:

>100_bases
CGGCGCGACTGATCGTAAGACGGTGCATCGGCGATATTGAAACGCCGGTTGGCGCCATGATGAAGCTCGGAGCAGACGAG
CCGGGCAGTTTTCTGTTTGA

Product: peptidylprolyl cis-trans isomerase-like protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MLALMKKMTRSPVGKLVLMIVIVGMAFWGVDAIVNQMRSGLGANVVSAGSRGLDPADLDFRVETVLRNINATAERPLSKS
EALEQGLIDQIVEVEKARITRLGYGESIGISPSPEAVVEEMNSIPAFQNPLTGELDPAMFRDRISQLGMSPAQFERQLQD
DILIRALSQAGRSAVYGPQVIANIQANYLGETREVAWFFFDASDAPAPEVPTDAEIKAYYDEHLERLKQPERRALDILRM
STDDFTGKVEVTDQEVATVYEATKSERFAAPDQRTYAELLFPTRDAARTAFGLLAGGADPNSVTGANSVQMRTARAEDIS
DQALQDAMFGPGRQSGAMYGPREVDGQWLVARLISVQPGAVKPLEEVAEEIRLGLARERAQLLFSAALETLDEALAAGND
LSQVAEDIGVPIISIAPVDQNGITEQGNQFTILSEVPEALPQAFRLPENEIGSRFDVASSVVLVAPRRIVPAATPELDAI
KDRVSAMIVSERTANAAEAAVEALTERVRAGSVTLDAAAAESGAQVDRLPEPVSRSNAQAMGVPGPLMQATFNNPAGSVI
SLPTGDGSVFAILKILSVSPPTPEMIASMGTAASADVTESLTADLEAAVDDEIRRAVKVKENASAIASYKRTITAAQ

Sequences:

>Translated_637_residues
MLALMKKMTRSPVGKLVLMIVIVGMAFWGVDAIVNQMRSGLGANVVSAGSRGLDPADLDFRVETVLRNINATAERPLSKS
EALEQGLIDQIVEVEKARITRLGYGESIGISPSPEAVVEEMNSIPAFQNPLTGELDPAMFRDRISQLGMSPAQFERQLQD
DILIRALSQAGRSAVYGPQVIANIQANYLGETREVAWFFFDASDAPAPEVPTDAEIKAYYDEHLERLKQPERRALDILRM
STDDFTGKVEVTDQEVATVYEATKSERFAAPDQRTYAELLFPTRDAARTAFGLLAGGADPNSVTGANSVQMRTARAEDIS
DQALQDAMFGPGRQSGAMYGPREVDGQWLVARLISVQPGAVKPLEEVAEEIRLGLARERAQLLFSAALETLDEALAAGND
LSQVAEDIGVPIISIAPVDQNGITEQGNQFTILSEVPEALPQAFRLPENEIGSRFDVASSVVLVAPRRIVPAATPELDAI
KDRVSAMIVSERTANAAEAAVEALTERVRAGSVTLDAAAAESGAQVDRLPEPVSRSNAQAMGVPGPLMQATFNNPAGSVI
SLPTGDGSVFAILKILSVSPPTPEMIASMGTAASADVTESLTADLEAAVDDEIRRAVKVKENASAIASYKRTITAAQ
>Mature_637_residues
MLALMKKMTRSPVGKLVLMIVIVGMAFWGVDAIVNQMRSGLGANVVSAGSRGLDPADLDFRVETVLRNINATAERPLSKS
EALEQGLIDQIVEVEKARITRLGYGESIGISPSPEAVVEEMNSIPAFQNPLTGELDPAMFRDRISQLGMSPAQFERQLQD
DILIRALSQAGRSAVYGPQVIANIQANYLGETREVAWFFFDASDAPAPEVPTDAEIKAYYDEHLERLKQPERRALDILRM
STDDFTGKVEVTDQEVATVYEATKSERFAAPDQRTYAELLFPTRDAARTAFGLLAGGADPNSVTGANSVQMRTARAEDIS
DQALQDAMFGPGRQSGAMYGPREVDGQWLVARLISVQPGAVKPLEEVAEEIRLGLARERAQLLFSAALETLDEALAAGND
LSQVAEDIGVPIISIAPVDQNGITEQGNQFTILSEVPEALPQAFRLPENEIGSRFDVASSVVLVAPRRIVPAATPELDAI
KDRVSAMIVSERTANAAEAAVEALTERVRAGSVTLDAAAAESGAQVDRLPEPVSRSNAQAMGVPGPLMQATFNNPAGSVI
SLPTGDGSVFAILKILSVSPPTPEMIASMGTAASADVTESLTADLEAAVDDEIRRAVKVKENASAIASYKRTITAAQ

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=497, Percent_Identity=22.5352112676056, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 68111; Mature: 68111

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLALMKKMTRSPVGKLVLMIVIVGMAFWGVDAIVNQMRSGLGANVVSAGSRGLDPADLDF
CHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCH
RVETVLRNINATAERPLSKSEALEQGLIDQIVEVEKARITRLGYGESIGISPSPEAVVEE
HHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
MNSIPAFQNPLTGELDPAMFRDRISQLGMSPAQFERQLQDDILIRALSQAGRSAVYGPQV
HHCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
IANIQANYLGETREVAWFFFDASDAPAPEVPTDAEIKAYYDEHLERLKQPERRALDILRM
HHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
STDDFTGKVEVTDQEVATVYEATKSERFAAPDQRTYAELLFPTRDAARTAFGLLAGGADP
CCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCC
NSVTGANSVQMRTARAEDISDQALQDAMFGPGRQSGAMYGPREVDGQWLVARLISVQPGA
CCCCCCCCCEEEHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
VKPLEEVAEEIRLGLARERAQLLFSAALETLDEALAAGNDLSQVAEDIGVPIISIAPVDQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECCCC
NGITEQGNQFTILSEVPEALPQAFRLPENEIGSRFDVASSVVLVAPRRIVPAATPELDAI
CCCCCCCCEEEEHHHHHHHHHHHHCCCCHHHCCHHHHHCCEEEECCCHHCCCCCCCHHHH
KDRVSAMIVSERTANAAEAAVEALTERVRAGSVTLDAAAAESGAQVDRLPEPVSRSNAQA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEHHHCCCCCCHHCCCCCHHCCCCCC
MGVPGPLMQATFNNPAGSVISLPTGDGSVFAILKILSVSPPTPEMIASMGTAASADVTES
CCCCCHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHH
LTADLEAAVDDEIRRAVKVKENASAIASYKRTITAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLALMKKMTRSPVGKLVLMIVIVGMAFWGVDAIVNQMRSGLGANVVSAGSRGLDPADLDF
CHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCH
RVETVLRNINATAERPLSKSEALEQGLIDQIVEVEKARITRLGYGESIGISPSPEAVVEE
HHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
MNSIPAFQNPLTGELDPAMFRDRISQLGMSPAQFERQLQDDILIRALSQAGRSAVYGPQV
HHCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
IANIQANYLGETREVAWFFFDASDAPAPEVPTDAEIKAYYDEHLERLKQPERRALDILRM
HHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
STDDFTGKVEVTDQEVATVYEATKSERFAAPDQRTYAELLFPTRDAARTAFGLLAGGADP
CCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCC
NSVTGANSVQMRTARAEDISDQALQDAMFGPGRQSGAMYGPREVDGQWLVARLISVQPGA
CCCCCCCCCEEEHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
VKPLEEVAEEIRLGLARERAQLLFSAALETLDEALAAGNDLSQVAEDIGVPIISIAPVDQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECCCC
NGITEQGNQFTILSEVPEALPQAFRLPENEIGSRFDVASSVVLVAPRRIVPAATPELDAI
CCCCCCCCEEEEHHHHHHHHHHHHCCCCHHHCCHHHHHCCEEEECCCHHCCCCCCCHHHH
KDRVSAMIVSERTANAAEAAVEALTERVRAGSVTLDAAAAESGAQVDRLPEPVSRSNAQA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEHHHCCCCCCHHCCCCCHHCCCCCC
MGVPGPLMQATFNNPAGSVISLPTGDGSVFAILKILSVSPPTPEMIASMGTAASADVTES
CCCCCHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHH
LTADLEAAVDDEIRRAVKVKENASAIASYKRTITAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]