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The map label for this gene is cpsA1 [H]

Identifier: 114799798

GI number: 114799798

Start: 705219

End: 706517

Strand: Reverse

Name: cpsA1 [H]

Synonym: HNE_0694

Alternate gene names: 114799798

Gene position: 706517-705219 (Counterclockwise)

Preceding gene: 114797080

Following gene: 114799423

Centisome position: 19.07

GC content: 63.13

Gene sequence:

>1299_bases
ATGCCGCAGGGCGAGCTGCGCACGGCGGACCCGAGCCTGGTGGAGCTTTACAAGAAGCTGCACGCCAACCCCGAGCTTTC
GTTCCGTGAGGTGGAGACGTCCAAGCTGATGGCGGATGAGCTGCGCGCGCTGGGCTTTACGGTGACCGAGGGCCTGGGCG
ACGATTGGGTGCGCGAGAAGGCGATGAAGGATATAGGGCAGGTGCTGCCCGGCGTGGGCGGCTATGGGGTCGTGGGCGTG
TTCGAGAACGGGCGCGGGCCGACGATCCTGATCCGCGCGGACATGGACGGCCTGCCTGTACCCGACCAGACGGGCTTTGA
ATTTGCCTCCACGATTGTCTCGCAGACCTGGACAGGCGTTGAGAGCCCGGTGATGCATGCCTGCGCCCATGATATTCACA
TGACGGTCTGGGTGGGCACGGCGCGGCGGCTGGTGGCCGAAGCTGACAAATGGAAGGGCACGCTGGTGATGATCGCCCAG
CCTGCCGAGGAGATTGGCCTGGGCGCGCAGGCGATGCTGGCCGATGGGCTGTATTCGGATTTTCCGCTGCCGGACTATAA
CCTTGCCCTGCATGTTTCAGCCGGCGCGCCGGCCGGCGTGATCAACTATTCTTCGGGCTATGCGCTGGCCAATGTCGACA
GTGTGGACATCACCGTGAAAGGCGCGGGCGGGCACGGGGCCTATCCGCACACGACACGCGACCCGATCCTGATCGCCAGC
CATATCGTTACCGCGTTGCAGAGCCTTGTCTCGCGCAATACCAATCCGCTGGAGTCTGCGGTTGTAACGGTCGGCTCGTT
CAAGGCGGGCGCGAAACACAACATCATTCCCGATGAAGCCGAACTGCTGATCACCGTGCGCTCCTATGATGACAAGACCC
GGCAGATGCTGCTGGATGGCATCACGCGGATTGCCGAGGGGACAGCGGCCGCCTTTGGCGCGCCCGAGCCTGAGATTACG
GTGGAGAGCGATTATACGCCGGCGACCTATAACGATCCGGAACTGACCAAGCGGGCGATGGCAGCCGTGGCCAGGAAACT
CGGCGAAGGCAATGTGCGCTCTGTGCCGCCGGTGATGGGCGGGGAAGATTTCAGCCAGTTTGCGCGTACCGATGAGGAAG
TGCCCGGTGTGATCTTCTGGCTGGGCGCGGTTGACCCCGACAAATATGCCGCCTCGCAGATTGACGGGATGCCCCTGCCC
TCGCTGCATTCGCCGCTGTTTGGCCCGGACTATGACCCGGCGATTGCCACAGGCGTGGAAGCGATGACGACAGCGGCGAT
TGATCTGTTCAAGGAGTAA

Upstream 100 bases:

>100_bases
CGCATGTGGAGGCGATGATCGCGACGCCGCCGAGGGCGGGCCGCGCGAGCTGCGGCCGGATGAGGGCGCGGGCGTTTCGA
CCGAGAGCGCCGTCAGCGGG

Downstream 100 bases:

>100_bases
CCATCCGCCGGAAGCGGCGAGAAGGAAAAGAGAGGCTGTCATGCTCCGAAACGCCCTGCTGATCGCCGCCGCTTTTGTTT
GCCTCCTGGGGCAGCCGGCG

Product: amidohydrolase, carboxypeptidase-type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MPQGELRTADPSLVELYKKLHANPELSFREVETSKLMADELRALGFTVTEGLGDDWVREKAMKDIGQVLPGVGGYGVVGV
FENGRGPTILIRADMDGLPVPDQTGFEFASTIVSQTWTGVESPVMHACAHDIHMTVWVGTARRLVAEADKWKGTLVMIAQ
PAEEIGLGAQAMLADGLYSDFPLPDYNLALHVSAGAPAGVINYSSGYALANVDSVDITVKGAGGHGAYPHTTRDPILIAS
HIVTALQSLVSRNTNPLESAVVTVGSFKAGAKHNIIPDEAELLITVRSYDDKTRQMLLDGITRIAEGTAAAFGAPEPEIT
VESDYTPATYNDPELTKRAMAAVARKLGEGNVRSVPPVMGGEDFSQFARTDEEVPGVIFWLGAVDPDKYAASQIDGMPLP
SLHSPLFGPDYDPAIATGVEAMTTAAIDLFKE

Sequences:

>Translated_432_residues
MPQGELRTADPSLVELYKKLHANPELSFREVETSKLMADELRALGFTVTEGLGDDWVREKAMKDIGQVLPGVGGYGVVGV
FENGRGPTILIRADMDGLPVPDQTGFEFASTIVSQTWTGVESPVMHACAHDIHMTVWVGTARRLVAEADKWKGTLVMIAQ
PAEEIGLGAQAMLADGLYSDFPLPDYNLALHVSAGAPAGVINYSSGYALANVDSVDITVKGAGGHGAYPHTTRDPILIAS
HIVTALQSLVSRNTNPLESAVVTVGSFKAGAKHNIIPDEAELLITVRSYDDKTRQMLLDGITRIAEGTAAAFGAPEPEIT
VESDYTPATYNDPELTKRAMAAVARKLGEGNVRSVPPVMGGEDFSQFARTDEEVPGVIFWLGAVDPDKYAASQIDGMPLP
SLHSPLFGPDYDPAIATGVEAMTTAAIDLFKE
>Mature_431_residues
PQGELRTADPSLVELYKKLHANPELSFREVETSKLMADELRALGFTVTEGLGDDWVREKAMKDIGQVLPGVGGYGVVGVF
ENGRGPTILIRADMDGLPVPDQTGFEFASTIVSQTWTGVESPVMHACAHDIHMTVWVGTARRLVAEADKWKGTLVMIAQP
AEEIGLGAQAMLADGLYSDFPLPDYNLALHVSAGAPAGVINYSSGYALANVDSVDITVKGAGGHGAYPHTTRDPILIASH
IVTALQSLVSRNTNPLESAVVTVGSFKAGAKHNIIPDEAELLITVRSYDDKTRQMLLDGITRIAEGTAAAFGAPEPEITV
ESDYTPATYNDPELTKRAMAAVARKLGEGNVRSVPPVMGGEDFSQFARTDEEVPGVIFWLGAVDPDKYAASQIDGMPLPS
LHSPLFGPDYDPAIATGVEAMTTAAIDLFKE

Specific function: Can release basic, acidic, aromatic, and, to a lesser extent, aliphatic amino acids [H]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=324, Percent_Identity=26.5432098765432, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: NA

Molecular weight: Translated: 46046; Mature: 45914

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQGELRTADPSLVELYKKLHANPELSFREVETSKLMADELRALGFTVTEGLGDDWVREK
CCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHH
AMKDIGQVLPGVGGYGVVGVFENGRGPTILIRADMDGLPVPDQTGFEFASTIVSQTWTGV
HHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCC
ESPVMHACAHDIHMTVWVGTARRLVAEADKWKGTLVMIAQPAEEIGLGAQAMLADGLYSD
CHHHHHHHHHHCEEEEEECHHHHHHHHHHCCCCEEEEEECCHHHHCCCHHHHHHCCCCCC
FPLPDYNLALHVSAGAPAGVINYSSGYALANVDSVDITVKGAGGHGAYPHTTRDPILIAS
CCCCCCCEEEEEECCCCCCEEECCCCEEEEECCEEEEEEEECCCCCCCCCCCCCCHHHHH
HIVTALQSLVSRNTNPLESAVVTVGSFKAGAKHNIIPDEAELLITVRSYDDKTRQMLLDG
HHHHHHHHHHHCCCCCHHHHHEEEECCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHH
ITRIAEGTAAAFGAPEPEITVESDYTPATYNDPELTKRAMAAVARKLGEGNVRSVPPVMG
HHHHHCCCHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GEDFSQFARTDEEVPGVIFWLGAVDPDKYAASQIDGMPLPSLHSPLFGPDYDPAIATGVE
CCHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
AMTTAAIDLFKE
HHHHHHHHHHCC
>Mature Secondary Structure 
PQGELRTADPSLVELYKKLHANPELSFREVETSKLMADELRALGFTVTEGLGDDWVREK
CCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHH
AMKDIGQVLPGVGGYGVVGVFENGRGPTILIRADMDGLPVPDQTGFEFASTIVSQTWTGV
HHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCC
ESPVMHACAHDIHMTVWVGTARRLVAEADKWKGTLVMIAQPAEEIGLGAQAMLADGLYSD
CHHHHHHHHHHCEEEEEECHHHHHHHHHHCCCCEEEEEECCHHHHCCCHHHHHHCCCCCC
FPLPDYNLALHVSAGAPAGVINYSSGYALANVDSVDITVKGAGGHGAYPHTTRDPILIAS
CCCCCCCEEEEEECCCCCCEEECCCCEEEEECCEEEEEEEECCCCCCCCCCCCCCHHHHH
HIVTALQSLVSRNTNPLESAVVTVGSFKAGAKHNIIPDEAELLITVRSYDDKTRQMLLDG
HHHHHHHHHHHCCCCCHHHHHEEEECCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHH
ITRIAEGTAAAFGAPEPEITVESDYTPATYNDPELTKRAMAAVARKLGEGNVRSVPPVMG
HHHHHCCCHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GEDFSQFARTDEEVPGVIFWLGAVDPDKYAASQIDGMPLPSLHSPLFGPDYDPAIATGVE
CCHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
AMTTAAIDLFKE
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7559343; 11427726; 1597179 [H]