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The map label for this gene is yhdH [H]

Identifier: 114799725

GI number: 114799725

Start: 3089214

End: 3090635

Strand: Reverse

Name: yhdH [H]

Synonym: HNE_2932

Alternate gene names: 114799725

Gene position: 3090635-3089214 (Counterclockwise)

Preceding gene: 114797109

Following gene: 114798618

Centisome position: 83.42

GC content: 60.41

Gene sequence:

>1422_bases
ATGGCAGATATTGGTCGCAAGTCGGAAACCTTCAGTTCGCGATTTGGCTTCATCATGGCTTCGGTCGGATCGGCCGTCGG
TCTCGGCAATTTCTGGCGGTTTCCCTACACGGCCGGTGAGAATGGCGGCGGCGCCTTCATCCTCATCTACATTCTCTGCG
TGGCATTCATCGCCTTGCCGCTTCTGATGGCGGAATATGCGATGGGCCGCAAATCCGGCATGTCGGCCATTGAGGGCGTC
CAGTCTCTCGCCCGCGCTGAAAGCCGCAGCCAGAACTGGGGCATCGTCACCTGGATCGGCTCGCTCACAGCCTTCTTCAT
CCTGAGTTTCTACATGGTCATTTCCGCCTGGCTGATCGCCTATGTGATCCAGGCCATCGGCGGAAACCTGAGCGGCACCA
CAGCCGAAGAATCCGGCCAGAACTTCCTCAACACCATCGGGCAGGGCGAACATCCGCTGAACTCGAAATGGTATATCCTG
ATGCTGCTCGGCCTGTTCATCGTGGCTAACATCTATGTCGTCGGCCGGGGCGTGAAGGGCGGGCTGGAGCGCGCCGCCAC
CATCCTGATGCCGCTGTTCTTCGTCATGGTGCTTGTGGTGGTCGGCTTCTCGCTTGCCAATGGCGATGTGGCGCGCACGG
TGTCCTTCATCTTCGAACCCAAATGGGAGGATGTCGGCTTCAAGACCTTCCTCGCCGCCCTCGGTCAGGCCTTCTTCTCC
ATCGGTGTCGGCGTCGGCCTGATGATCACCTATGGCGCCTATCTCGACCGCGCCACCAGCATCCCGAAATCCTCCGTCAT
CATTGCGGGCTCTGACACATTCGTGGCGCTCATCGCCGGCTTTGCCATCTTCCCCATCGTGTTTGCGGCCGGCCTTAATG
AAGGCTCCGGCCCCAGCCTGTTCTTCGTCTCCATGCCGGTGGCCTTCGAGGCCATCCCCGGCGGGGCCATCTTCGCCGTC
ATTTTCTTCTCGCTGGCGCTGTTTGCTGCCTTCACCTCATCCATCTCGCTGATGGAAGTGGGCGTGTCCTGGCTTGAAGA
ACGCCAGGGCGTCACGCGCATCGGCGCAGCGTCCGGCGTCGGCTTTGTCCTCTTCATGGTCGGGGCGGCGTATGTCTTCT
CGCTCGAATATCTCGACTTCATGGACTTCATGACCGAAGGCCTGCTGCTGCCGCTCGGCGGTTTCCTGGCTGCAATCTTT
GCCGGCTGGATTCTCAGCCGCGAGATGCTCACCTCCGAACTCGGCGAGGGCACGATCATGAATGCCTGGCGGTTCCTGAT
CCGCTGGTTCGTGCCGCCCTTCATCGGGCTCGTCCTGGTGTTCGGCTTCATGGACAAGATCCAGGACCAGTATCACGTCC
AGCTGCCTGGCGTGCTCGAGATGCTTCTCGGCCCTAACTATGAACTGGCAGGGCAGGAGTAG

Upstream 100 bases:

>100_bases
ACCCACCGTGTTATCTGACCCGGAATTGCGCCATTTGCGTTGATTTCTGACCGCTTGCCGCTACGGTCCCGCCAAACATT
GCCTCTGGGGAGCGTAATTC

Downstream 100 bases:

>100_bases
TTACGCTTCAACTGGGCCTGTCCTCCCGCGGAGGATGGGCCCGATGTTTAAGCCAGGGTGAGAGGAAGCTAATCGCCGAG
AGCGGTCATTGACTCAGCAC

Product: sodium-dependent symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MADIGRKSETFSSRFGFIMASVGSAVGLGNFWRFPYTAGENGGGAFILIYILCVAFIALPLLMAEYAMGRKSGMSAIEGV
QSLARAESRSQNWGIVTWIGSLTAFFILSFYMVISAWLIAYVIQAIGGNLSGTTAEESGQNFLNTIGQGEHPLNSKWYIL
MLLGLFIVANIYVVGRGVKGGLERAATILMPLFFVMVLVVVGFSLANGDVARTVSFIFEPKWEDVGFKTFLAALGQAFFS
IGVGVGLMITYGAYLDRATSIPKSSVIIAGSDTFVALIAGFAIFPIVFAAGLNEGSGPSLFFVSMPVAFEAIPGGAIFAV
IFFSLALFAAFTSSISLMEVGVSWLEERQGVTRIGAASGVGFVLFMVGAAYVFSLEYLDFMDFMTEGLLLPLGGFLAAIF
AGWILSREMLTSELGEGTIMNAWRFLIRWFVPPFIGLVLVFGFMDKIQDQYHVQLPGVLEMLLGPNYELAGQE

Sequences:

>Translated_473_residues
MADIGRKSETFSSRFGFIMASVGSAVGLGNFWRFPYTAGENGGGAFILIYILCVAFIALPLLMAEYAMGRKSGMSAIEGV
QSLARAESRSQNWGIVTWIGSLTAFFILSFYMVISAWLIAYVIQAIGGNLSGTTAEESGQNFLNTIGQGEHPLNSKWYIL
MLLGLFIVANIYVVGRGVKGGLERAATILMPLFFVMVLVVVGFSLANGDVARTVSFIFEPKWEDVGFKTFLAALGQAFFS
IGVGVGLMITYGAYLDRATSIPKSSVIIAGSDTFVALIAGFAIFPIVFAAGLNEGSGPSLFFVSMPVAFEAIPGGAIFAV
IFFSLALFAAFTSSISLMEVGVSWLEERQGVTRIGAASGVGFVLFMVGAAYVFSLEYLDFMDFMTEGLLLPLGGFLAAIF
AGWILSREMLTSELGEGTIMNAWRFLIRWFVPPFIGLVLVFGFMDKIQDQYHVQLPGVLEMLLGPNYELAGQE
>Mature_472_residues
ADIGRKSETFSSRFGFIMASVGSAVGLGNFWRFPYTAGENGGGAFILIYILCVAFIALPLLMAEYAMGRKSGMSAIEGVQ
SLARAESRSQNWGIVTWIGSLTAFFILSFYMVISAWLIAYVIQAIGGNLSGTTAEESGQNFLNTIGQGEHPLNSKWYILM
LLGLFIVANIYVVGRGVKGGLERAATILMPLFFVMVLVVVGFSLANGDVARTVSFIFEPKWEDVGFKTFLAALGQAFFSI
GVGVGLMITYGAYLDRATSIPKSSVIIAGSDTFVALIAGFAIFPIVFAAGLNEGSGPSLFFVSMPVAFEAIPGGAIFAVI
FFSLALFAAFTSSISLMEVGVSWLEERQGVTRIGAASGVGFVLFMVGAAYVFSLEYLDFMDFMTEGLLLPLGGFLAAIFA
GWILSREMLTSELGEGTIMNAWRFLIRWFVPPFIGLVLVFGFMDKIQDQYHVQLPGVLEMLLGPNYELAGQE

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI188528618, Length=374, Percent_Identity=26.4705882352941, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI4507043, Length=378, Percent_Identity=26.1904761904762, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI289191351, Length=505, Percent_Identity=23.5643564356436, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI4557046, Length=505, Percent_Identity=23.5643564356436, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI289191377, Length=505, Percent_Identity=23.5643564356436, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI92859670, Length=454, Percent_Identity=24.4493392070485, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI21361581, Length=454, Percent_Identity=22.0264317180617, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI4507041, Length=497, Percent_Identity=22.5352112676056, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI134304856, Length=363, Percent_Identity=24.5179063360882, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI7657587, Length=456, Percent_Identity=22.3684210526316, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI171184408, Length=389, Percent_Identity=22.879177377892, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI171184406, Length=389, Percent_Identity=22.879177377892, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI171184404, Length=389, Percent_Identity=22.879177377892, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI194018524, Length=319, Percent_Identity=24.4514106583072, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI33354281, Length=321, Percent_Identity=23.98753894081, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI11181770, Length=311, Percent_Identity=25.4019292604502, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI5032097, Length=370, Percent_Identity=23.5135135135135, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI197276623, Length=353, Percent_Identity=23.5127478753541, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI54607094, Length=353, Percent_Identity=23.5127478753541, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI6005715, Length=506, Percent_Identity=21.3438735177866, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI12408638, Length=289, Percent_Identity=25.2595155709343, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI218563756, Length=370, Percent_Identity=22.7027027027027, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI58219014, Length=317, Percent_Identity=24.6056782334385, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI21361693, Length=124, Percent_Identity=31.4516129032258, Blast_Score=70, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17554804, Length=478, Percent_Identity=24.8953974895398, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI25146584, Length=412, Percent_Identity=24.2718446601942, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17555248, Length=425, Percent_Identity=23.2941176470588, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71998244, Length=452, Percent_Identity=24.7787610619469, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI212642127, Length=139, Percent_Identity=27.3381294964029, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17535731, Length=129, Percent_Identity=32.5581395348837, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17569475, Length=384, Percent_Identity=23.6979166666667, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534083, Length=515, Percent_Identity=20.3883495145631, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI133952791, Length=64, Percent_Identity=45.3125, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI17136952, Length=507, Percent_Identity=23.0769230769231, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281364394, Length=507, Percent_Identity=23.0769230769231, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI28574704, Length=507, Percent_Identity=23.0769230769231, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI17136950, Length=507, Percent_Identity=23.0769230769231, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI28574702, Length=507, Percent_Identity=23.0769230769231, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI45550877, Length=391, Percent_Identity=24.8081841432225, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI19921352, Length=479, Percent_Identity=25.2609603340292, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24584353, Length=479, Percent_Identity=25.2609603340292, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI45551183, Length=391, Percent_Identity=24.8081841432225, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24762620, Length=501, Percent_Identity=22.5548902195609, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI281365034, Length=470, Percent_Identity=24.0425531914894, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24661428, Length=451, Percent_Identity=23.9467849223947, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI45551088, Length=508, Percent_Identity=23.6220472440945, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24652942, Length=508, Percent_Identity=23.6220472440945, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI281363702, Length=496, Percent_Identity=23.3870967741935, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI19921936, Length=425, Percent_Identity=24, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI221329674, Length=372, Percent_Identity=24.1935483870968, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24639514, Length=372, Percent_Identity=24.1935483870968, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24655079, Length=311, Percent_Identity=24.1157556270096, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24639853, Length=415, Percent_Identity=26.5060240963855, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24639516, Length=304, Percent_Identity=24.3421052631579, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281363700, Length=346, Percent_Identity=24.5664739884393, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 50999; Mature: 50868

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADIGRKSETFSSRFGFIMASVGSAVGLGNFWRFPYTAGENGGGAFILIYILCVAFIALP
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LLMAEYAMGRKSGMSAIEGVQSLARAESRSQNWGIVTWIGSLTAFFILSFYMVISAWLIA
HHHHHHHHCHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YVIQAIGGNLSGTTAEESGQNFLNTIGQGEHPLNSKWYILMLLGLFIVANIYVVGRGVKG
HHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCHH
GLERAATILMPLFFVMVLVVVGFSLANGDVARTVSFIFEPKWEDVGFKTFLAALGQAFFS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
IGVGVGLMITYGAYLDRATSIPKSSVIIAGSDTFVALIAGFAIFPIVFAAGLNEGSGPSL
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEE
FFVSMPVAFEAIPGGAIFAVIFFSLALFAAFTSSISLMEVGVSWLEERQGVTRIGAASGV
EEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHH
GFVLFMVGAAYVFSLEYLDFMDFMTEGLLLPLGGFLAAIFAGWILSREMLTSELGEGTIM
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
NAWRFLIRWFVPPFIGLVLVFGFMDKIQDQYHVQLPGVLEMLLGPNYELAGQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ADIGRKSETFSSRFGFIMASVGSAVGLGNFWRFPYTAGENGGGAFILIYILCVAFIALP
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]