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The map label for this gene is nhaA1 [H]

Identifier: 114799585

GI number: 114799585

Start: 2857851

End: 2858591

Strand: Direct

Name: nhaA1 [H]

Synonym: HNE_2697

Alternate gene names: 114799585

Gene position: 2857851-2858591 (Clockwise)

Preceding gene: 114800353

Following gene: 114799951

Centisome position: 77.13

GC content: 60.86

Gene sequence:

>741_bases
ATGCTCCGCTTCACACCCTTTCTCGCGCTCGGCTTTGCGGGCCTTGCCCTGCTGCCTGCCTGCGCGCAGGGCGGCGGTAC
ACCCGACAAGGCCGAAATCGAGACAATCGTGCGGGAATACATCCTCGCCAATCCCGAGATCATTGAGGAGGCGCTGGTCG
CCCTCACCGAGAAGGAACGCCTCGCCCAGGCCAGCGCCACACAGGCCGCCATCGCCGACAGCAAGGACGCCCTCTACAAT
GACAGCAACGATTATTTTGTCGGCCCGGAAGACGCCGCCGTGACGGTCGTCGAGTTTTTTGACTATCGCTGCGGCTATTG
CAAACGGTCTGCTGAATGGACTGCAAACCTGCCCGAGACCTATGACGGCCAGGTCCGCGTCGTGTTCAAGGAATATCCGA
TCTTCGGCGACATCAGCGAGACCGCCGCCCTTGCCGCGCTCGCCTCCGGCCGCCAGGGCAAATACATCGACATGCACCTT
GCCCTGATGGCCCTCAAATCAAACGATGAGCTGACAGAGCAGAAGATCGACGAGCTTGCCATGCAGCTCGGCATCGATGT
CCAGCGCATGCGCGCAGACATGAAATCGGACAGCGTGAAGAACCAGCTTGCTGACATGCAGGCGCTCGGCCGCACGCTGA
ATGTTGGCGGCACACCTGGCTATTTCGTCGGCGATCAGGCCATCGAAGGCGCCAATCTTCCCAAGATCGACGAAGTTATC
CGCGCCGAAATCGCCGGCTGA

Upstream 100 bases:

>100_bases
TAAAAGGGCGGGTAAACCCTCTGTGAGGATGGGTGGACGCGCCCGGCCCGGTGCCTATAGTCCGGCGAGCTGAAATCAGG
GATTCTTCACTATGAACCGT

Downstream 100 bases:

>100_bases
TCAGACCTTCATATTCCGGTCTGCCAGCAGCGTATCGAAATAGGCGATGGTCTTGGAAAGGCCGTCGCGCAACTCGACCG
ACGGCTCCCATTTCAGGATT

Product: outer membrane protein

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 1 [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MLRFTPFLALGFAGLALLPACAQGGGTPDKAEIETIVREYILANPEIIEEALVALTEKERLAQASATQAAIADSKDALYN
DSNDYFVGPEDAAVTVVEFFDYRCGYCKRSAEWTANLPETYDGQVRVVFKEYPIFGDISETAALAALASGRQGKYIDMHL
ALMALKSNDELTEQKIDELAMQLGIDVQRMRADMKSDSVKNQLADMQALGRTLNVGGTPGYFVGDQAIEGANLPKIDEVI
RAEIAG

Sequences:

>Translated_246_residues
MLRFTPFLALGFAGLALLPACAQGGGTPDKAEIETIVREYILANPEIIEEALVALTEKERLAQASATQAAIADSKDALYN
DSNDYFVGPEDAAVTVVEFFDYRCGYCKRSAEWTANLPETYDGQVRVVFKEYPIFGDISETAALAALASGRQGKYIDMHL
ALMALKSNDELTEQKIDELAMQLGIDVQRMRADMKSDSVKNQLADMQALGRTLNVGGTPGYFVGDQAIEGANLPKIDEVI
RAEIAG
>Mature_246_residues
MLRFTPFLALGFAGLALLPACAQGGGTPDKAEIETIVREYILANPEIIEEALVALTEKERLAQASATQAAIADSKDALYN
DSNDYFVGPEDAAVTVVEFFDYRCGYCKRSAEWTANLPETYDGQVRVVFKEYPIFGDISETAALAALASGRQGKYIDMHL
ALMALKSNDELTEQKIDELAMQLGIDVQRMRADMKSDSVKNQLADMQALGRTLNVGGTPGYFVGDQAIEGANLPKIDEVI
RAEIAG

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 26711; Mature: 26711

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRFTPFLALGFAGLALLPACAQGGGTPDKAEIETIVREYILANPEIIEEALVALTEKER
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LAQASATQAAIADSKDALYNDSNDYFVGPEDAAVTVVEFFDYRCGYCKRSAEWTANLPET
HHHHHHHHHHHCCCCHHHCCCCCCEEECCCCHHHHHHHHHHHHCCHHCCCCCCCCCCCCC
YDGQVRVVFKEYPIFGDISETAALAALASGRQGKYIDMHLALMALKSNDELTEQKIDELA
CCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHH
MQLGIDVQRMRADMKSDSVKNQLADMQALGRTLNVGGTPGYFVGDQAIEGANLPKIDEVI
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCEEECCHHCCCCCCCHHHHHH
RAEIAG
HHHCCC
>Mature Secondary Structure
MLRFTPFLALGFAGLALLPACAQGGGTPDKAEIETIVREYILANPEIIEEALVALTEKER
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LAQASATQAAIADSKDALYNDSNDYFVGPEDAAVTVVEFFDYRCGYCKRSAEWTANLPET
HHHHHHHHHHHCCCCHHHCCCCCCEEECCCCHHHHHHHHHHHHCCHHCCCCCCCCCCCCC
YDGQVRVVFKEYPIFGDISETAALAALASGRQGKYIDMHLALMALKSNDELTEQKIDELA
CCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHH
MQLGIDVQRMRADMKSDSVKNQLADMQALGRTLNVGGTPGYFVGDQAIEGANLPKIDEVI
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCEEECCHHCCCCCCCHHHHHH
RAEIAG
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA