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The map label for this gene is yqiG [H]

Identifier: 114799497

GI number: 114799497

Start: 180418

End: 181509

Strand: Reverse

Name: yqiG [H]

Synonym: HNE_0194

Alternate gene names: 114799497

Gene position: 181509-180418 (Counterclockwise)

Preceding gene: 114800272

Following gene: 114798672

Centisome position: 4.9

GC content: 63.74

Gene sequence:

>1092_bases
ATGACCTCACTTCATTCTCAAATGACCCTCACCCGTGGCCCCGCCATGAAGAACCGCTTCATGCTCGCGCCGCTCACCAA
CATGCAGAGCCATGCCGATGGCACGCTCAGCGATGACGAGTTTCACTGGCTGGCGAAGCGCGCCGAAGGCGGCTTTGGCT
TGACGATGACCTGCGCGGCGCATGTGCAAGCTGATGGCCAGGGCTTTCCCGGCCAGCTCGGCGTGTTTGATGACAAGCAC
CTCCCAGGCCTCACGCGGCTGGCAAAGGCGCTGAACAGCAACGACACCCATTCGGTCGTGCAGCTTCACCATGCGGGCAT
GCGCACGCCCCGAGAACTGATCAGCGGACGTGCGCCGCTGTGCCCCTCTGCTGACGAAGAAACCGGCGCGCGGGCGATGA
CGCTTGATGAAGTCAAACAGGTGGCCGACGACTTCGTCGCCGCAGCCAAGCGCAGCGAGAAGGCCGGCTTCCACGGCGTC
GAGCTGCACGGCGCACACGGATACCTGCTCTGCCAGTTCATCAGCGCGGACATCAACAAGCGCGAAGACGAGTATGGCGG
TGACTTTGATGGCCGCACCAGACTGCTGCGCGACATCATTGCGGGCGTGCGGGCAGAATGCGGGAAAGACTTCTCACTCG
GCGTGCGCCTCTCACCGGAACGCTTCGGCATGGACATCGGCGAAATCCGCCGCCTCTCCAGCGACCTGATGACGGGCGGG
GACATCGATTATCTCGACATGTCCCTGTGGGACACGTTCAAGGAACCGGAAGACCCGAGCTTCAAGGGCCGCCCCTTGGT
CGAGTGGTTCACCGGCCTGCCGCGCGGCAATTGCCGCCTGGGCGCCGCCGGCAAGCTGACCACCGGCGAAAGCTGCCAGC
GCGCCATGGACGCCGGGCTCGACTATGTCGTGATCGGGCGCGGCGCGATCCTGCACCATGACTTCCCGAAGAAGGTCGAA
ACAGACGCGGGTTTCACGCCGATTGCCCTGCCTGTTCCAGAAGCGCATCTGGTGGCCGAGGGCCTTGGCCCGGTGTTCGT
GAATTACATGAAGACCTGGAAGGGCTTTGTGGCAGAAGCGGCCACGGCCTGA

Upstream 100 bases:

>100_bases
AGTTCATGAGCCATATGGCGACCCTGGGCGCGGATATTCGGAGCTGACCCTGCCCCGAGGGAAAAATTGACGAACCCGAT
TCCCGCGACAGGATTGGCGC

Downstream 100 bases:

>100_bases
GCCATACTTGACTTGAGCCATACTTGACTTGAGGCGGGGGGTGGATCACTCCCCGGCCTCATGATCATCGCAATTGACGG
CACGACAGCTTCTGGCAAGG

Product: NADH:flavin oxidoreductase/NADH oxidase family protein

Products: NADP; Cytotoxic compound [C]

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MTSLHSQMTLTRGPAMKNRFMLAPLTNMQSHADGTLSDDEFHWLAKRAEGGFGLTMTCAAHVQADGQGFPGQLGVFDDKH
LPGLTRLAKALNSNDTHSVVQLHHAGMRTPRELISGRAPLCPSADEETGARAMTLDEVKQVADDFVAAAKRSEKAGFHGV
ELHGAHGYLLCQFISADINKREDEYGGDFDGRTRLLRDIIAGVRAECGKDFSLGVRLSPERFGMDIGEIRRLSSDLMTGG
DIDYLDMSLWDTFKEPEDPSFKGRPLVEWFTGLPRGNCRLGAAGKLTTGESCQRAMDAGLDYVVIGRGAILHHDFPKKVE
TDAGFTPIALPVPEAHLVAEGLGPVFVNYMKTWKGFVAEAATA

Sequences:

>Translated_363_residues
MTSLHSQMTLTRGPAMKNRFMLAPLTNMQSHADGTLSDDEFHWLAKRAEGGFGLTMTCAAHVQADGQGFPGQLGVFDDKH
LPGLTRLAKALNSNDTHSVVQLHHAGMRTPRELISGRAPLCPSADEETGARAMTLDEVKQVADDFVAAAKRSEKAGFHGV
ELHGAHGYLLCQFISADINKREDEYGGDFDGRTRLLRDIIAGVRAECGKDFSLGVRLSPERFGMDIGEIRRLSSDLMTGG
DIDYLDMSLWDTFKEPEDPSFKGRPLVEWFTGLPRGNCRLGAAGKLTTGESCQRAMDAGLDYVVIGRGAILHHDFPKKVE
TDAGFTPIALPVPEAHLVAEGLGPVFVNYMKTWKGFVAEAATA
>Mature_362_residues
TSLHSQMTLTRGPAMKNRFMLAPLTNMQSHADGTLSDDEFHWLAKRAEGGFGLTMTCAAHVQADGQGFPGQLGVFDDKHL
PGLTRLAKALNSNDTHSVVQLHHAGMRTPRELISGRAPLCPSADEETGARAMTLDEVKQVADDFVAAAKRSEKAGFHGVE
LHGAHGYLLCQFISADINKREDEYGGDFDGRTRLLRDIIAGVRAECGKDFSLGVRLSPERFGMDIGEIRRLSSDLMTGGD
IDYLDMSLWDTFKEPEDPSFKGRPLVEWFTGLPRGNCRLGAAGKLTTGESCQRAMDAGLDYVVIGRGAILHHDFPKKVET
DAGFTPIALPVPEAHLVAEGLGPVFVNYMKTWKGFVAEAATA

Specific function: Unknown

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=339, Percent_Identity=28.6135693215339, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789463, Length=208, Percent_Identity=26.9230769230769, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17559804, Length=357, Percent_Identity=26.890756302521, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17559802, Length=242, Percent_Identity=31.8181818181818, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI72001454, Length=241, Percent_Identity=30.7053941908714, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17565138, Length=242, Percent_Identity=30.5785123966942, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17564188, Length=357, Percent_Identity=26.0504201680672, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17540738, Length=242, Percent_Identity=29.7520661157025, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17566914, Length=340, Percent_Identity=25, Blast_Score=81, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6321973, Length=218, Percent_Identity=29.8165137614679, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6325086, Length=221, Percent_Identity=27.1493212669683, Blast_Score=91, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39471; Mature: 39340

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLHSQMTLTRGPAMKNRFMLAPLTNMQSHADGTLSDDEFHWLAKRAEGGFGLTMTCAA
CCCCHHHEEECCCCCCCCCEEEEECCCCHHCCCCCCCCCHHHHHHHHCCCCCCEEEEEEE
HVQADGQGFPGQLGVFDDKHLPGLTRLAKALNSNDTHSVVQLHHAGMRTPRELISGRAPL
EEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHCCCCCC
CPSADEETGARAMTLDEVKQVADDFVAAAKRSEKAGFHGVELHGAHGYLLCQFISADINK
CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCC
REDEYGGDFDGRTRLLRDIIAGVRAECGKDFSLGVRLSPERFGMDIGEIRRLSSDLMTGG
CCHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHCCCHHHHHHHHHHHCCCC
DIDYLDMSLWDTFKEPEDPSFKGRPLVEWFTGLPRGNCRLGAAGKLTTGESCQRAMDAGL
CCCEEHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHCCC
DYVVIGRGAILHHDFPKKVETDAGFTPIALPVPEAHLVAEGLGPVFVNYMKTWKGFVAEA
CEEEECCCEEEECCCCCHHCCCCCCCEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHH
ATA
CCC
>Mature Secondary Structure 
TSLHSQMTLTRGPAMKNRFMLAPLTNMQSHADGTLSDDEFHWLAKRAEGGFGLTMTCAA
CCCHHHEEECCCCCCCCCEEEEECCCCHHCCCCCCCCCHHHHHHHHCCCCCCEEEEEEE
HVQADGQGFPGQLGVFDDKHLPGLTRLAKALNSNDTHSVVQLHHAGMRTPRELISGRAPL
EEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHCCCCCC
CPSADEETGARAMTLDEVKQVADDFVAAAKRSEKAGFHGVELHGAHGYLLCQFISADINK
CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCC
REDEYGGDFDGRTRLLRDIIAGVRAECGKDFSLGVRLSPERFGMDIGEIRRLSSDLMTGG
CCHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHCCCHHHHHHHHHHHCCCC
DIDYLDMSLWDTFKEPEDPSFKGRPLVEWFTGLPRGNCRLGAAGKLTTGESCQRAMDAGL
CCCEEHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHCCC
DYVVIGRGAILHHDFPKKVETDAGFTPIALPVPEAHLVAEGLGPVFVNYMKTWKGFVAEA
CEEEECCCEEEECCCCCHHCCCCCCCEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHH
ATA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; N-ethylmaleimide [C]

Specific reaction: NADPH + N-ethylmaleimide = NADP + Cytotoxic compound [C]

General reaction: Reduction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]