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The map label for this gene is 114799464

Identifier: 114799464

GI number: 114799464

Start: 2039612

End: 2040907

Strand: Direct

Name: 114799464

Synonym: HNE_1970

Alternate gene names: NA

Gene position: 2039612-2040907 (Clockwise)

Preceding gene: 114799823

Following gene: 114800552

Centisome position: 55.05

GC content: 59.88

Gene sequence:

>1296_bases
ATGAAGAAACTACTCCTGAGCGTGGCGTTTGGCGCACTTCTTACAGCCTGCGCGCCCGACGTGCCGCAGACGGCGGATAC
TGCCGCGGCACCGGCTGCCGAAGCAGAAGCTCCAACGCAAGAGCGGTCCGCCGCTGAGGAGATGCACTTCCGCACGCTGG
TGCTGGATACTCACCTTGATACCCCCGCCTATTTCCATGATCCCAGCTACACCTTCTCAAAGAAGGGCAGCTTCGACGAA
GACGGCACCCATGTGGACCTGCCCCGCATGAATGAAGGCGGCCTGGATGGTGGCTTCTGGGTCATCTTCACCCCGCAAGG
CCCGCTGGATGAAGCCTCCTATCTGGCAGCCCGCAACATGGCGGTGCTCCGCCAGATGTCGATCCGGGAATTTGCGGCGA
AGTATGCAGGCGATGTCGAACTCGCCTTCTCGACCTCCGATGCAGAGCGCATCGCAGCAGCGGGCAAAAAGATCGTCTTC
CAGAGCATGGAGAACTCCTATCCGCTGGGCACTGATATTTCGATGCTCGACACCTTCTATGTCGGCGGCCTTCGGATGAT
TGCCCCGGTACACTTCCGTAACAATCAGTTTGCGGACAGCGCGACCGATGTGAATGAAGTTTTCGGTGGCCTCAGCCCTC
TGGGAGAGGAACTGGTGCGCGAAGCAAACCGGCTTGGCCTTATTCTGGACGGCTCGCACGCATCTGACGGAACCGTGCGC
GACATGCTGGAGATTTCGACGACGCCGCTGATCCTTTCACACTCCGGCCCAAAGGCGGTTTACGACCACCCTCGCAACGT
TCCCGACGACCTGCTGATCGCTATCGCAGAGGACGGCGGCGTCATTCAGATCAATGCTTATGGCAGCTACCTGGAAGCCC
TGCCCGCAAGCCCAGAGCGCCTGGCGGCACTTGCCGAGCTCGAAGCCGAATTTGGCAGCGACACCTCCGCAATGGATGAA
GCAACCATGACGGCCTATCGCGCCGCGTATGAAACGGTGAACACGTCCTTCCCGGCGCCTCGCTCCACCTTTGAGAAGTT
CATGGAACATCTTCTCTACACGCTCGAACTCGTGGGCCCGGAACATGTCGGCGTCGGTGCAGACTGGGATGGCGGCGGCG
GCGTTGATGGAATGAAGGACATTGTCGACCTTCCAAAGGTGACCGCAGCGCTGGTTGAGGCGGGCTACTCTGAGGAAGAC
GTTGCAAATATCTGGGGCGGCAACGTCCTGCGGCTTATGTCGGAAGTGGATGCCGCGCGAAGCGCTGATCTCTCTTCCCC
GCAAGTCCTGAACTGA

Upstream 100 bases:

>100_bases
GGGCCTGACCTTTTCTTTGCATGCCCGGCGGTTGACCGCACGCGCTTACGGGTGAACATCCCGCAATCTTTGGACTCATA
TTCTTGCGGGGCTTGATCGG

Downstream 100 bases:

>100_bases
CGATGGAATGGCTGAGCGTCCTTCCGCCAGTAGCGGCTATTATCGTCGCCATCTGGTCACGGAACGTATATTGGGCGCTC
GGCCTCGCCATTCTTCTTTC

Product: dipeptidase family protein

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MKKLLLSVAFGALLTACAPDVPQTADTAAAPAAEAEAPTQERSAAEEMHFRTLVLDTHLDTPAYFHDPSYTFSKKGSFDE
DGTHVDLPRMNEGGLDGGFWVIFTPQGPLDEASYLAARNMAVLRQMSIREFAAKYAGDVELAFSTSDAERIAAAGKKIVF
QSMENSYPLGTDISMLDTFYVGGLRMIAPVHFRNNQFADSATDVNEVFGGLSPLGEELVREANRLGLILDGSHASDGTVR
DMLEISTTPLILSHSGPKAVYDHPRNVPDDLLIAIAEDGGVIQINAYGSYLEALPASPERLAALAELEAEFGSDTSAMDE
ATMTAYRAAYETVNTSFPAPRSTFEKFMEHLLYTLELVGPEHVGVGADWDGGGGVDGMKDIVDLPKVTAALVEAGYSEED
VANIWGGNVLRLMSEVDAARSADLSSPQVLN

Sequences:

>Translated_431_residues
MKKLLLSVAFGALLTACAPDVPQTADTAAAPAAEAEAPTQERSAAEEMHFRTLVLDTHLDTPAYFHDPSYTFSKKGSFDE
DGTHVDLPRMNEGGLDGGFWVIFTPQGPLDEASYLAARNMAVLRQMSIREFAAKYAGDVELAFSTSDAERIAAAGKKIVF
QSMENSYPLGTDISMLDTFYVGGLRMIAPVHFRNNQFADSATDVNEVFGGLSPLGEELVREANRLGLILDGSHASDGTVR
DMLEISTTPLILSHSGPKAVYDHPRNVPDDLLIAIAEDGGVIQINAYGSYLEALPASPERLAALAELEAEFGSDTSAMDE
ATMTAYRAAYETVNTSFPAPRSTFEKFMEHLLYTLELVGPEHVGVGADWDGGGGVDGMKDIVDLPKVTAALVEAGYSEED
VANIWGGNVLRLMSEVDAARSADLSSPQVLN
>Mature_431_residues
MKKLLLSVAFGALLTACAPDVPQTADTAAAPAAEAEAPTQERSAAEEMHFRTLVLDTHLDTPAYFHDPSYTFSKKGSFDE
DGTHVDLPRMNEGGLDGGFWVIFTPQGPLDEASYLAARNMAVLRQMSIREFAAKYAGDVELAFSTSDAERIAAAGKKIVF
QSMENSYPLGTDISMLDTFYVGGLRMIAPVHFRNNQFADSATDVNEVFGGLSPLGEELVREANRLGLILDGSHASDGTVR
DMLEISTTPLILSHSGPKAVYDHPRNVPDDLLIAIAEDGGVIQINAYGSYLEALPASPERLAALAELEAEFGSDTSAMDE
ATMTAYRAAYETVNTSFPAPRSTFEKFMEHLLYTLELVGPEHVGVGADWDGGGGVDGMKDIVDLPKVTAALVEAGYSEED
VANIWGGNVLRLMSEVDAARSADLSSPQVLN

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI11641269, Length=426, Percent_Identity=26.7605633802817, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI189458885, Length=391, Percent_Identity=26.0869565217391, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI4758190, Length=391, Percent_Identity=26.0869565217391, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI193211608, Length=350, Percent_Identity=26, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI193211610, Length=350, Percent_Identity=26, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI221475880, Length=420, Percent_Identity=27.1428571428571, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281362638, Length=345, Percent_Identity=29.8550724637681, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI281362636, Length=345, Percent_Identity=29.8550724637681, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI161083233, Length=345, Percent_Identity=29.2753623188406, Blast_Score=144, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 46236; Mature: 46236

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLLSVAFGALLTACAPDVPQTADTAAAPAAEAEAPTQERSAAEEMHFRTLVLDTHLD
CHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHEEEEEECCCC
TPAYFHDPSYTFSKKGSFDEDGTHVDLPRMNEGGLDGGFWVIFTPQGPLDEASYLAARNM
CCCEECCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHH
AVLRQMSIREFAAKYAGDVELAFSTSDAERIAAAGKKIVFQSMENSYPLGTDISMLDTFY
HHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
VGGLRMIAPVHFRNNQFADSATDVNEVFGGLSPLGEELVREANRLGLILDGSHASDGTVR
HCCEEEEEEEEECCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHEEEEEECCCCCCCHHH
DMLEISTTPLILSHSGPKAVYDHPRNVPDDLLIAIAEDGGVIQINAYGSYLEALPASPER
HHHHHCCCCEEEECCCCCHHHCCCCCCCCHHEEEEECCCCEEEEECCCHHHHHCCCCHHH
LAALAELEAEFGSDTSAMDEATMTAYRAAYETVNTSFPAPRSTFEKFMEHLLYTLELVGP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
EHVGVGADWDGGGGVDGMKDIVDLPKVTAALVEAGYSEEDVANIWGGNVLRLMSEVDAAR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHH
SADLSSPQVLN
HCCCCCCCCCC
>Mature Secondary Structure
MKKLLLSVAFGALLTACAPDVPQTADTAAAPAAEAEAPTQERSAAEEMHFRTLVLDTHLD
CHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHEEEEEECCCC
TPAYFHDPSYTFSKKGSFDEDGTHVDLPRMNEGGLDGGFWVIFTPQGPLDEASYLAARNM
CCCEECCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHH
AVLRQMSIREFAAKYAGDVELAFSTSDAERIAAAGKKIVFQSMENSYPLGTDISMLDTFY
HHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
VGGLRMIAPVHFRNNQFADSATDVNEVFGGLSPLGEELVREANRLGLILDGSHASDGTVR
HCCEEEEEEEEECCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHEEEEEECCCCCCCHHH
DMLEISTTPLILSHSGPKAVYDHPRNVPDDLLIAIAEDGGVIQINAYGSYLEALPASPER
HHHHHCCCCEEEECCCCCHHHCCCCCCCCHHEEEEECCCCEEEEECCCHHHHHCCCCHHH
LAALAELEAEFGSDTSAMDEATMTAYRAAYETVNTSFPAPRSTFEKFMEHLLYTLELVGP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
EHVGVGADWDGGGGVDGMKDIVDLPKVTAALVEAGYSEEDVANIWGGNVLRLMSEVDAAR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHH
SADLSSPQVLN
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]