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The map label for this gene is ubiA [H]

Identifier: 114799354

GI number: 114799354

Start: 1397975

End: 1399102

Strand: Reverse

Name: ubiA [H]

Synonym: HNE_1368

Alternate gene names: 114799354

Gene position: 1399102-1397975 (Counterclockwise)

Preceding gene: 114797331

Following gene: 114797219

Centisome position: 37.76

GC content: 66.58

Gene sequence:

>1128_bases
ATGACCATACCCCAACCGCCTGAAAACCCCGGAAATTTCGCCGTCCCCGCCGATTCCGCCCTACCCGGCTGGCTCGCGGG
CCTGCCCAAGGCGTGGCAGCCCTACGCCATGCTCGCCCGGCTCGACCGGCCCGTCGGCGTGTGGCTGCTGTTCCTGCCCT
GCCTGATGGGCCTCGGCTTTGCCCGGCTCACCACCGGCCTTTACCTGATCGACCTTCTCTGGACGCTCCTCTTCCTCATC
GGCGCCATCGTGATGCGCGGGGCGGGCTGCACCTGGAACGACATCACCGACAAGGATTTCGACGCCAAGGTCGCCCGCAC
CGCGGCCCGGCCCATCCCCTCGGGCGCCGTCACGACGAAACAGGCCTATATCTTCCTGCTAGCGCAGCTCGCCGTCGGCT
TCCTGATCTGGCTCGCCCTGCCCTGGGACGCAAAGATCGCCGCCCTGCTCGCCCTGCCGCTGGTGGCCATCTACCCTTAC
ACCAAGCGTGTCACCTGGTGGCCGCAGGCCTGGCTGGGGCTCACCTTCAACTGGGGCGTCTTCGTTGGCGCCGCGACCGC
CAGTGTCATCACCGGGCCAGTCTACATCCTCTATGCCGGCCTCATCCTGTGGACGATCGCTTATGACACGATCTATGCCC
TTCAGGACCGGGAAGACGACGCCCTGATCGGTGTCCGCTCCACCGCGCGCCTCTTCGGCGAGCGGGCTGTGCTGATCTCC
TTCGGCTTCCACATGGGCGCCGCCGCCCTCATCGGCTTTGCCGCCTACGCCCAGGGCGCCGGGCGGCTCGGTGCGCTCAC
GGCGCTCCTCTTCCTCGCCCACGGCGCCTGGCAGGCGATGACACTGAAAACCAAAGGCGAAGGCAAGGCGCTGGCGATGT
TCAAATCCAACGTCCATGCCGGCGCCATCGTCGCCATCGGCTTCCTGATCGCCGCGATGTTCCCTCAAGATAATTCCAGC
CGCCTCTACGCCGATCATGAAACGGTTCCCGAAGCCGTGGCCCTGCCCTTCGGCCTTGAGCAACAGCCTGCGCCGGAAGT
CACTTACCCCGACACCTGGTTTGCCAGCGACATGGAACGCGCCCTTGAGGCCGAAGCGGTCAAGCGCGGCGACGCCCCAA
CCCCGTGA

Upstream 100 bases:

>100_bases
CCAGGCCGCCGCTGTTAAGGTGTGGCCTTTGCGCAACGTCCTGTGGTTTTGAAATCACACCCCGTGCGAGTGGCTGCGGG
ATCGCTTATATCATCCTCCT

Downstream 100 bases:

>100_bases
CGCGGGGCGCCTGCGCGCCTATACTCCCCTCAAGCCGGACTGGCAGAAGGAGGCTCTCATGACCGTCGCAATCGAAATGG
TATCAGACCCCGTCTGTCCC

Product: 4-hydroxybenzoate polyprenyl transferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MTIPQPPENPGNFAVPADSALPGWLAGLPKAWQPYAMLARLDRPVGVWLLFLPCLMGLGFARLTTGLYLIDLLWTLLFLI
GAIVMRGAGCTWNDITDKDFDAKVARTAARPIPSGAVTTKQAYIFLLAQLAVGFLIWLALPWDAKIAALLALPLVAIYPY
TKRVTWWPQAWLGLTFNWGVFVGAATASVITGPVYILYAGLILWTIAYDTIYALQDREDDALIGVRSTARLFGERAVLIS
FGFHMGAAALIGFAAYAQGAGRLGALTALLFLAHGAWQAMTLKTKGEGKALAMFKSNVHAGAIVAIGFLIAAMFPQDNSS
RLYADHETVPEAVALPFGLEQQPAPEVTYPDTWFASDMERALEAEAVKRGDAPTP

Sequences:

>Translated_375_residues
MTIPQPPENPGNFAVPADSALPGWLAGLPKAWQPYAMLARLDRPVGVWLLFLPCLMGLGFARLTTGLYLIDLLWTLLFLI
GAIVMRGAGCTWNDITDKDFDAKVARTAARPIPSGAVTTKQAYIFLLAQLAVGFLIWLALPWDAKIAALLALPLVAIYPY
TKRVTWWPQAWLGLTFNWGVFVGAATASVITGPVYILYAGLILWTIAYDTIYALQDREDDALIGVRSTARLFGERAVLIS
FGFHMGAAALIGFAAYAQGAGRLGALTALLFLAHGAWQAMTLKTKGEGKALAMFKSNVHAGAIVAIGFLIAAMFPQDNSS
RLYADHETVPEAVALPFGLEQQPAPEVTYPDTWFASDMERALEAEAVKRGDAPTP
>Mature_374_residues
TIPQPPENPGNFAVPADSALPGWLAGLPKAWQPYAMLARLDRPVGVWLLFLPCLMGLGFARLTTGLYLIDLLWTLLFLIG
AIVMRGAGCTWNDITDKDFDAKVARTAARPIPSGAVTTKQAYIFLLAQLAVGFLIWLALPWDAKIAALLALPLVAIYPYT
KRVTWWPQAWLGLTFNWGVFVGAATASVITGPVYILYAGLILWTIAYDTIYALQDREDDALIGVRSTARLFGERAVLISF
GFHMGAAALIGFAAYAQGAGRLGALTALLFLAHGAWQAMTLKTKGEGKALAMFKSNVHAGAIVAIGFLIAAMFPQDNSSR
LYADHETVPEAVALPFGLEQQPAPEVTYPDTWFASDMERALEAEAVKRGDAPTP

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=315, Percent_Identity=39.6825396825397, Blast_Score=187, Evalue=2e-47,
Organism=Escherichia coli, GI1790473, Length=276, Percent_Identity=35.1449275362319, Blast_Score=137, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17553718, Length=309, Percent_Identity=36.8932038834951, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI32565247, Length=314, Percent_Identity=35.9872611464968, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17553720, Length=371, Percent_Identity=30.9973045822102, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI32565245, Length=159, Percent_Identity=41.5094339622642, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32565243, Length=155, Percent_Identity=41.2903225806452, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6324370, Length=234, Percent_Identity=42.3076923076923, Blast_Score=165, Evalue=9e-42,
Organism=Drosophila melanogaster, GI21355567, Length=309, Percent_Identity=40.1294498381877, Blast_Score=194, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 40526; Mature: 40395

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIPQPPENPGNFAVPADSALPGWLAGLPKAWQPYAMLARLDRPVGVWLLFLPCLMGLGF
CCCCCCCCCCCCEECCCCCCCCHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCH
ARLTTGLYLIDLLWTLLFLIGAIVMRGAGCTWNDITDKDFDAKVARTAARPIPSGAVTTK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHH
QAYIFLLAQLAVGFLIWLALPWDAKIAALLALPLVAIYPYTKRVTWWPQAWLGLTFNWGV
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEECCHHHHCCEEECHH
FVGAATASVITGPVYILYAGLILWTIAYDTIYALQDREDDALIGVRSTARLFGERAVLIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEHHHHHHHHCCCEEEEE
FGFHMGAAALIGFAAYAQGAGRLGALTALLFLAHGAWQAMTLKTKGEGKALAMFKSNVHA
ECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCCC
GAIVAIGFLIAAMFPQDNSSRLYADHETVPEAVALPFGLEQQPAPEVTYPDTWFASDMER
HHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
ALEAEAVKRGDAPTP
HHHHHHHHCCCCCCC
>Mature Secondary Structure 
TIPQPPENPGNFAVPADSALPGWLAGLPKAWQPYAMLARLDRPVGVWLLFLPCLMGLGF
CCCCCCCCCCCEECCCCCCCCHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCH
ARLTTGLYLIDLLWTLLFLIGAIVMRGAGCTWNDITDKDFDAKVARTAARPIPSGAVTTK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHH
QAYIFLLAQLAVGFLIWLALPWDAKIAALLALPLVAIYPYTKRVTWWPQAWLGLTFNWGV
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEECCHHHHCCEEECHH
FVGAATASVITGPVYILYAGLILWTIAYDTIYALQDREDDALIGVRSTARLFGERAVLIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEHHHHHHHHCCCEEEEE
FGFHMGAAALIGFAAYAQGAGRLGALTALLFLAHGAWQAMTLKTKGEGKALAMFKSNVHA
ECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCCC
GAIVAIGFLIAAMFPQDNSSRLYADHETVPEAVALPFGLEQQPAPEVTYPDTWFASDMER
HHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
ALEAEAVKRGDAPTP
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA