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The map label for this gene is tlpA [H]

Identifier: 114799212

GI number: 114799212

Start: 3602896

End: 3603486

Strand: Direct

Name: tlpA [H]

Synonym: HNE_3466

Alternate gene names: 114799212

Gene position: 3602896-3603486 (Clockwise)

Preceding gene: 114797243

Following gene: 114799390

Centisome position: 97.24

GC content: 61.93

Gene sequence:

>591_bases
ATGACCCGCTACGCCTATCTCGGCCTCTTCTTGATCGGCCTTGGTGCGATTGTCTATGTGCTGATGAGCGCTGCGACAGG
AAAGCCCGCCGGTAATCCGCTTGAAGCCTTCGCCACAGGCCAGATGGAAAAGCTGGATTTCGGCAGCGCCGGCCAGCCAA
TCCCCGCCGGCACATTCACAGATACAGACAACACGTCCCAGACGCTTGAGGTCTTCAAGGGCAAGACGATCCTCGTCAAC
TACTGGGCCACCTGGTGCCCGCCCTGCGAGAAGGAAATGCCCTCTCTCGGCGCCCTGCAGACCGCGCGCAGCGGCGATAC
GTTCGAAGTCGTCGCCCTAAGCGTCGATACGGTTGAAGATGTGGACTATGCCAAACGCCGCCTGACCGAACTGGGCGCCT
CCAATATTCCCTTCCGCCATGCCCCCATGGATGCCGGGGACATCATCTACGGCGCCGGCGTGCGCGGCTTCCCCACAACG
ATCATTTACGGTCCCGATGGTCTGGAGATCGCGCGCCTGGCAGGTGAAGCGGACTGGGCGTCAGCCGAAGCCGTGCAGTT
CATCGACGCGGCTATCAAGGCCGCACGCTAG

Upstream 100 bases:

>100_bases
AGGTGTCGCGGCAAAACGCCCGCCCCACATCATCTGGCCTTTGTCATCTGCCATTGCCATATCCTCTTATTCGTAACCGA
CGTCAGTGAAGGGCCGTCCC

Downstream 100 bases:

>100_bases
GGCAGCGCCTGCAGCGCGGCCTTGATGCGCCCAAACTGCTCCACCATCCGCACTTCTGGTGCCGGTGTCCGGTCTGGCAA
CGGGCCACCGGCAGGCCACA

Product: putative thiol:disulfide interchange protein

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MTRYAYLGLFLIGLGAIVYVLMSAATGKPAGNPLEAFATGQMEKLDFGSAGQPIPAGTFTDTDNTSQTLEVFKGKTILVN
YWATWCPPCEKEMPSLGALQTARSGDTFEVVALSVDTVEDVDYAKRRLTELGASNIPFRHAPMDAGDIIYGAGVRGFPTT
IIYGPDGLEIARLAGEADWASAEAVQFIDAAIKAAR

Sequences:

>Translated_196_residues
MTRYAYLGLFLIGLGAIVYVLMSAATGKPAGNPLEAFATGQMEKLDFGSAGQPIPAGTFTDTDNTSQTLEVFKGKTILVN
YWATWCPPCEKEMPSLGALQTARSGDTFEVVALSVDTVEDVDYAKRRLTELGASNIPFRHAPMDAGDIIYGAGVRGFPTT
IIYGPDGLEIARLAGEADWASAEAVQFIDAAIKAAR
>Mature_195_residues
TRYAYLGLFLIGLGAIVYVLMSAATGKPAGNPLEAFATGQMEKLDFGSAGQPIPAGTFTDTDNTSQTLEVFKGKTILVNY
WATWCPPCEKEMPSLGALQTARSGDTFEVVALSVDTVEDVDYAKRRLTELGASNIPFRHAPMDAGDIIYGAGVRGFPTTI
IYGPDGLEIARLAGEADWASAEAVQFIDAAIKAAR

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 20861; Mature: 20730

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRYAYLGLFLIGLGAIVYVLMSAATGKPAGNPLEAFATGQMEKLDFGSAGQPIPAGTFT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCC
DTDNTSQTLEVFKGKTILVNYWATWCPPCEKEMPSLGALQTARSGDTFEVVALSVDTVED
CCCCCHHHHHHHCCCEEEEEECCCCCCCHHHHCCCCCHHHHCCCCCCEEEEEEECCCHHH
VDYAKRRLTELGASNIPFRHAPMDAGDIIYGAGVRGFPTTIIYGPDGLEIARLAGEADWA
HHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCCCEEHHHCCCCCCC
SAEAVQFIDAAIKAAR
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRYAYLGLFLIGLGAIVYVLMSAATGKPAGNPLEAFATGQMEKLDFGSAGQPIPAGTFT
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCC
DTDNTSQTLEVFKGKTILVNYWATWCPPCEKEMPSLGALQTARSGDTFEVVALSVDTVED
CCCCCHHHHHHHCCCEEEEEECCCCCCCHHHHCCCCCHHHHCCCCCCEEEEEEECCCHHH
VDYAKRRLTELGASNIPFRHAPMDAGDIIYGAGVRGFPTTIIYGPDGLEIARLAGEADWA
HHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCCCEEHHHCCCCCCC
SAEAVQFIDAAIKAAR
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]