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The map label for this gene is 114799085

Identifier: 114799085

GI number: 114799085

Start: 1499960

End: 1500718

Strand: Direct

Name: 114799085

Synonym: HNE_1473

Alternate gene names: NA

Gene position: 1499960-1500718 (Clockwise)

Preceding gene: 114800049

Following gene: 114798526

Centisome position: 40.48

GC content: 60.34

Gene sequence:

>759_bases
ATGAACGCGACCGCCCGATCCGCTGAAATGTCCTGTTCGGATGCTGAGTGGAAAGTACGCTGTGATCTGGCTGCCGCCTA
CCGGCTGATCGCCCTGTTCGGATGGGATGACCTGGTCTTCACACACATTTCTGCGCGTGTTCCGGGGCCGGATCACCATT
TCCTGATCAATCCCTACGGCTGGTTGTTCGAGGAGATCACGGCCTCCTCTCTCGTCAAGGTAGATCTGGATGGCCAGAAG
GTCGGGCCGTCTGACGCGATGGTGAATCCGGCCGGGTTCACCATCCACTCTGCGGTGCATGAGGCGCGCGAGGATGCCCA
CTGCGTGCTGCATTTGCATACTGTCGACGGTGTAGCGGTGTCCTGCCTGGAAGAGGGGCTGCTGCCGCTCAACCAGACGG
CCATGCTGCTGAATGGCCAGCTTGCCTACCATGACTATGAAGGCGTCGCGCTCAATCACGATGAGCGCCCGCGCCTTGTT
GCGGATCTGGGCAGCAGCAATGTCATGATCCTTCGGAACCATGGCACAATGTCTGTTGGTCATTCCGTCGCGGCGGCTTT
CTCCTTCATGTATTTTCTGGAGCGGGCCTGCTCGATCCAGATCGCAGCGCAGGGTGGCGGGAAGCTCCGTATGCCGCAGG
ACGACGTGCAGGCCGTTGTCGAGGCGCAATCCAAAAGCATGTCGCAGGCTGCTGACATGCTCGTCTGGCCGGCCCTGTTG
CGCCGGCTCAACCGGGTCAGTCCTGGCTTTGATTCCTGA

Upstream 100 bases:

>100_bases
GGCAACAATATGTGCGTCTTCTGGATATTGAGCTCGACTAGATCTGTCTGCATACCTGCCCAGTCTCAACCGTCAGATGT
CAGACAGAAGGTTTTCTCAA

Downstream 100 bases:

>100_bases
GCCACTCCTTCCGCTCGGCTGGATAACGATATCCTCAGAATACACATTTTAGGATCGGAAGAAAAATGTCTGCCCCTGCA
AAGAAAAGGTTCCGGCTACC

Product: class II aldolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MNATARSAEMSCSDAEWKVRCDLAAAYRLIALFGWDDLVFTHISARVPGPDHHFLINPYGWLFEEITASSLVKVDLDGQK
VGPSDAMVNPAGFTIHSAVHEAREDAHCVLHLHTVDGVAVSCLEEGLLPLNQTAMLLNGQLAYHDYEGVALNHDERPRLV
ADLGSSNVMILRNHGTMSVGHSVAAAFSFMYFLERACSIQIAAQGGGKLRMPQDDVQAVVEAQSKSMSQAADMLVWPALL
RRLNRVSPGFDS

Sequences:

>Translated_252_residues
MNATARSAEMSCSDAEWKVRCDLAAAYRLIALFGWDDLVFTHISARVPGPDHHFLINPYGWLFEEITASSLVKVDLDGQK
VGPSDAMVNPAGFTIHSAVHEAREDAHCVLHLHTVDGVAVSCLEEGLLPLNQTAMLLNGQLAYHDYEGVALNHDERPRLV
ADLGSSNVMILRNHGTMSVGHSVAAAFSFMYFLERACSIQIAAQGGGKLRMPQDDVQAVVEAQSKSMSQAADMLVWPALL
RRLNRVSPGFDS
>Mature_252_residues
MNATARSAEMSCSDAEWKVRCDLAAAYRLIALFGWDDLVFTHISARVPGPDHHFLINPYGWLFEEITASSLVKVDLDGQK
VGPSDAMVNPAGFTIHSAVHEAREDAHCVLHLHTVDGVAVSCLEEGLLPLNQTAMLLNGQLAYHDYEGVALNHDERPRLV
ADLGSSNVMILRNHGTMSVGHSVAAAFSFMYFLERACSIQIAAQGGGKLRMPQDDVQAVVEAQSKSMSQAADMLVWPALL
RRLNRVSPGFDS

Specific function: Unknown

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family [H]

Homologues:

Organism=Homo sapiens, GI29826323, Length=206, Percent_Identity=47.5728155339806, Blast_Score=187, Evalue=7e-48,
Organism=Homo sapiens, GI29826325, Length=206, Percent_Identity=47.5728155339806, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI29826319, Length=206, Percent_Identity=47.5728155339806, Blast_Score=186, Evalue=1e-47,
Organism=Homo sapiens, GI29826321, Length=198, Percent_Identity=48.989898989899, Blast_Score=186, Evalue=1e-47,
Organism=Homo sapiens, GI9943848, Length=195, Percent_Identity=41.025641025641, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI9951927, Length=199, Percent_Identity=40.7035175879397, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI62912453, Length=199, Percent_Identity=40.7035175879397, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI297307158, Length=197, Percent_Identity=39.5939086294416, Blast_Score=151, Evalue=6e-37,
Organism=Homo sapiens, GI9257192, Length=197, Percent_Identity=39.5939086294416, Blast_Score=151, Evalue=6e-37,
Organism=Homo sapiens, GI9257190, Length=197, Percent_Identity=39.5939086294416, Blast_Score=150, Evalue=7e-37,
Organism=Homo sapiens, GI297307160, Length=197, Percent_Identity=39.5939086294416, Blast_Score=150, Evalue=8e-37,
Organism=Homo sapiens, GI89276787, Length=197, Percent_Identity=39.5939086294416, Blast_Score=150, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI115533216, Length=248, Percent_Identity=39.9193548387097, Blast_Score=171, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI115533218, Length=248, Percent_Identity=39.9193548387097, Blast_Score=170, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI71989560, Length=206, Percent_Identity=37.378640776699, Blast_Score=134, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71989544, Length=197, Percent_Identity=38.0710659898477, Blast_Score=134, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71989555, Length=197, Percent_Identity=38.0710659898477, Blast_Score=134, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71989550, Length=206, Percent_Identity=37.378640776699, Blast_Score=134, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI71989541, Length=206, Percent_Identity=37.378640776699, Blast_Score=134, Evalue=4e-32,
Organism=Drosophila melanogaster, GI281363755, Length=195, Percent_Identity=40.5128205128205, Blast_Score=143, Evalue=9e-35,
Organism=Drosophila melanogaster, GI281363751, Length=195, Percent_Identity=40.5128205128205, Blast_Score=143, Evalue=9e-35,
Organism=Drosophila melanogaster, GI24655690, Length=195, Percent_Identity=40.5128205128205, Blast_Score=143, Evalue=9e-35,
Organism=Drosophila melanogaster, GI24655685, Length=195, Percent_Identity=40.5128205128205, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI281363763, Length=195, Percent_Identity=40.5128205128205, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI281363757, Length=195, Percent_Identity=40.5128205128205, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI17136738, Length=195, Percent_Identity=40.5128205128205, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI281363761, Length=195, Percent_Identity=40.5128205128205, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281363759, Length=195, Percent_Identity=40.5128205128205, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281363753, Length=195, Percent_Identity=40.5128205128205, Blast_Score=142, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: NA

Molecular weight: Translated: 27470; Mature: 27470

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNATARSAEMSCSDAEWKVRCDLAAAYRLIALFGWDDLVFTHISARVPGPDHHFLINPYG
CCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCHHHEEHHHEECCCCCCCEEEECCHH
WLFEEITASSLVKVDLDGQKVGPSDAMVNPAGFTIHSAVHEAREDAHCVLHLHTVDGVAV
HHHHHHHHCCEEEEECCCCCCCCCCCEECCCCCHHHHHHHHHCCCCEEEEEEEECCCHHH
SCLEEGLLPLNQTAMLLNGQLAYHDYEGVALNHDERPRLVADLGSSNVMILRNHGTMSVG
HHHHHCCCCCCCEEEEECCEEEEECCCCEEECCCCCCCEEEECCCCCEEEEECCCCCHHH
HSVAAAFSFMYFLERACSIQIAAQGGGKLRMPQDDVQAVVEAQSKSMSQAADMLVWPALL
HHHHHHHHHHHHHHHHCEEEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLNRVSPGFDS
HHHHHCCCCCCC
>Mature Secondary Structure
MNATARSAEMSCSDAEWKVRCDLAAAYRLIALFGWDDLVFTHISARVPGPDHHFLINPYG
CCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCHHHEEHHHEECCCCCCCEEEECCHH
WLFEEITASSLVKVDLDGQKVGPSDAMVNPAGFTIHSAVHEAREDAHCVLHLHTVDGVAV
HHHHHHHHCCEEEEECCCCCCCCCCCEECCCCCHHHHHHHHHCCCCEEEEEEEECCCHHH
SCLEEGLLPLNQTAMLLNGQLAYHDYEGVALNHDERPRLVADLGSSNVMILRNHGTMSVG
HHHHHCCCCCCCEEEEECCEEEEECCCCEEECCCCCCCEEEECCCCCEEEEECCCCCHHH
HSVAAAFSFMYFLERACSIQIAAQGGGKLRMPQDDVQAVVEAQSKSMSQAADMLVWPALL
HHHHHHHHHHHHHHHHCEEEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLNRVSPGFDS
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]