| Definition | Hyphomonas neptunium ATCC 15444 chromosome, complete genome. |
|---|---|
| Accession | NC_008358 |
| Length | 3,705,021 |
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The map label for this gene is fabG [H]
Identifier: 114799002
GI number: 114799002
Start: 2042361
End: 2043104
Strand: Direct
Name: fabG [H]
Synonym: HNE_1972
Alternate gene names: 114799002
Gene position: 2042361-2043104 (Clockwise)
Preceding gene: 114800552
Following gene: 114799737
Centisome position: 55.12
GC content: 61.96
Gene sequence:
>744_bases ATGGCCCGCAACCTGTTCGATCTGACTGGAAAAGTCGCCCTTGTAACCGGCGGCAGCCGCGGTCTCGGCTTTGAGATGGT GAAGGCTTTTGCGGAGAATGGCGCCGATGTGATCATCGCCAGCCGCAAGCTGGATGCGTGTGAGGCGGCCGCTGAAGAAG TGCGAAAGCTCGGCCGGAAGGCCTTTGCGTTTGCCGCCCATTGCGGGCGCTGGGACGACATCGACGCCCTGATCGAGGCC TCCTACGGGCATTTCGGACGGGTCGATATTCTCGTGAACAATGCCGGCTCCGGACCGCGCATGGCCAGCGATGAGGTGAC AGAAAACCTCTTTGATTCCGTGTTGAACCTGAACTTCAAAGGCCCGTTCCGTCTGGCCAGCCAGGTCGCCAAGCGCATGG CAGACGGCGATGGCGGCTCGATCATCAACATCTCGTCGTCAGGCAGCCTAGTGCCCCTGCCCCATGTGGTGCCCTATGGC TCGGCCAAGGCAGCAATCAACGCCATGAGCCTGTCTCTGGCGCATGAGTATGCGCCCAAGGTGCGGGTGAACACGATCTG CCCTGGGCCGTTCCTGACCGACATTGCCAAGGCCTGGCCCGAACAGATGCGCCAGTCTGCGGATAACGCCCTTGGGCGTC CGGGTTACCCCGAGGAGATCGTGACGGCGGCTCTTTATCTGGCGAGTCCGGCCTCAAGTTTCACGACAGGGTCTTTGTTG CGCGTGGATGGCAGCGCCGCCTGA
Upstream 100 bases:
>100_bases CGGCCTGACGCCTCACCTCGCGGCAGGCCGCCCGATTGGCGGTTGATGGCGTTCGCTGGTTGCCTGATGGTCTGGCGCAA GCAGAAACTGGAGGAAACCG
Downstream 100 bases:
>100_bases AAAACCTTAGAAAAACAGCGTCAAAACTGTGACAAGGCCCGCCTCTGGCGGGCCTTTTTGCGTCACCGCCCGGACAAACT TGGACAAAACGGGACAAATT
Product: short chain dehydrogenase/reductase family oxidoreductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 247; Mature: 246
Protein sequence:
>247_residues MARNLFDLTGKVALVTGGSRGLGFEMVKAFAENGADVIIASRKLDACEAAAEEVRKLGRKAFAFAAHCGRWDDIDALIEA SYGHFGRVDILVNNAGSGPRMASDEVTENLFDSVLNLNFKGPFRLASQVAKRMADGDGGSIINISSSGSLVPLPHVVPYG SAKAAINAMSLSLAHEYAPKVRVNTICPGPFLTDIAKAWPEQMRQSADNALGRPGYPEEIVTAALYLASPASSFTTGSLL RVDGSAA
Sequences:
>Translated_247_residues MARNLFDLTGKVALVTGGSRGLGFEMVKAFAENGADVIIASRKLDACEAAAEEVRKLGRKAFAFAAHCGRWDDIDALIEA SYGHFGRVDILVNNAGSGPRMASDEVTENLFDSVLNLNFKGPFRLASQVAKRMADGDGGSIINISSSGSLVPLPHVVPYG SAKAAINAMSLSLAHEYAPKVRVNTICPGPFLTDIAKAWPEQMRQSADNALGRPGYPEEIVTAALYLASPASSFTTGSLL RVDGSAA >Mature_246_residues ARNLFDLTGKVALVTGGSRGLGFEMVKAFAENGADVIIASRKLDACEAAAEEVRKLGRKAFAFAAHCGRWDDIDALIEAS YGHFGRVDILVNNAGSGPRMASDEVTENLFDSVLNLNFKGPFRLASQVAKRMADGDGGSIINISSSGSLVPLPHVVPYGS AKAAINAMSLSLAHEYAPKVRVNTICPGPFLTDIAKAWPEQMRQSADNALGRPGYPEEIVTAALYLASPASSFTTGSLLR VDGSAA
Specific function: Catalyzes A Reversible Reduction Of 5-Ketoglutanate To Form D-Gluconate. Dependent On Nadp, Almost Inactive With NAD. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=31.2757201646091, Blast_Score=123, Evalue=2e-28, Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=31.6205533596838, Blast_Score=122, Evalue=3e-28, Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=31.8897637795276, Blast_Score=116, Evalue=2e-26, Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=31.6872427983539, Blast_Score=114, Evalue=6e-26, Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=33.8541666666667, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI126723191, Length=205, Percent_Identity=32.6829268292683, Blast_Score=104, Evalue=7e-23, Organism=Homo sapiens, GI126723750, Length=246, Percent_Identity=28.0487804878049, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI7705925, Length=243, Percent_Identity=32.0987654320988, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI59889578, Length=230, Percent_Identity=33.4782608695652, Blast_Score=94, Evalue=8e-20, Organism=Homo sapiens, GI40254992, Length=236, Percent_Identity=32.2033898305085, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI4758504, Length=266, Percent_Identity=30.0751879699248, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI209862901, Length=199, Percent_Identity=30.1507537688442, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI19923983, Length=199, Percent_Identity=30.1507537688442, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI7706318, Length=198, Percent_Identity=25.7575757575758, Blast_Score=81, Evalue=7e-16, Organism=Homo sapiens, GI4503301, Length=247, Percent_Identity=28.7449392712551, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI40254986, Length=251, Percent_Identity=26.2948207171315, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI4557649, Length=197, Percent_Identity=30.4568527918782, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI31542939, Length=188, Percent_Identity=31.3829787234043, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI66933014, Length=249, Percent_Identity=28.9156626506024, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI83715985, Length=265, Percent_Identity=28.3018867924528, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI15277342, Length=265, Percent_Identity=30.188679245283, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI210032110, Length=200, Percent_Identity=24, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI7705855, Length=217, Percent_Identity=26.7281105990783, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI4504505, Length=196, Percent_Identity=29.0816326530612, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI142976729, Length=227, Percent_Identity=25.1101321585903, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI302344755, Length=127, Percent_Identity=34.6456692913386, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI224922801, Length=170, Percent_Identity=30.5882352941176, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI20149619, Length=199, Percent_Identity=29.6482412060301, Blast_Score=64, Evalue=9e-11, Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=32.9268292682927, Blast_Score=127, Evalue=6e-31, Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=35.2, Blast_Score=125, Evalue=4e-30, Organism=Escherichia coli, GI1787905, Length=241, Percent_Identity=34.8547717842324, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=30.7053941908714, Blast_Score=103, Evalue=7e-24, Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=31.9838056680162, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=33.2046332046332, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=32.5301204819277, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI2367175, Length=243, Percent_Identity=31.2757201646091, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1788459, Length=240, Percent_Identity=29.5833333333333, Blast_Score=91, Evalue=5e-20, Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=30.5220883534137, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1786812, Length=253, Percent_Identity=29.2490118577075, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1789057, Length=252, Percent_Identity=27.3809523809524, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1787526, Length=236, Percent_Identity=27.1186440677966, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=27.2222222222222, Blast_Score=61, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=30.3149606299213, Blast_Score=117, Evalue=6e-27, Organism=Caenorhabditis elegans, GI17560676, Length=243, Percent_Identity=30.4526748971193, Blast_Score=116, Evalue=8e-27, Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=31.8548387096774, Blast_Score=116, Evalue=8e-27, Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=32.1705426356589, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=32.2448979591837, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI17536025, Length=254, Percent_Identity=31.8897637795276, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=30, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17561272, Length=248, Percent_Identity=32.258064516129, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17562910, Length=256, Percent_Identity=29.6875, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=32.2448979591837, Blast_Score=94, Evalue=4e-20, Organism=Caenorhabditis elegans, GI25147288, Length=243, Percent_Identity=32.9218106995885, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI193204405, Length=272, Percent_Identity=32.7205882352941, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17562906, Length=259, Percent_Identity=29.7297297297297, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=28.0769230769231, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=29.0697674418605, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=29.7297297297297, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562904, Length=250, Percent_Identity=28.8, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562990, Length=267, Percent_Identity=30.7116104868914, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=30.188679245283, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=29.3893129770992, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17560150, Length=270, Percent_Identity=29.2592592592593, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17555612, Length=207, Percent_Identity=32.3671497584541, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=27.0992366412214, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17551412, Length=257, Percent_Identity=29.9610894941634, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17560220, Length=271, Percent_Identity=30.2583025830258, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=29.1187739463602, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17564282, Length=240, Percent_Identity=26.25, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17560332, Length=259, Percent_Identity=26.6409266409266, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=28.735632183908, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71982365, Length=246, Percent_Identity=26.4227642276423, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71997099, Length=208, Percent_Identity=29.3269230769231, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17568967, Length=236, Percent_Identity=27.9661016949153, Blast_Score=68, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17538182, Length=252, Percent_Identity=28.1746031746032, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17538486, Length=199, Percent_Identity=31.1557788944724, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI193203115, Length=243, Percent_Identity=25.9259259259259, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI193203117, Length=245, Percent_Identity=25.3061224489796, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17508895, Length=186, Percent_Identity=26.8817204301075, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=28.8, Blast_Score=84, Evalue=2e-17, Organism=Saccharomyces cerevisiae, GI6322861, Length=232, Percent_Identity=27.5862068965517, Blast_Score=71, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6322227, Length=217, Percent_Identity=27.1889400921659, Blast_Score=62, Evalue=6e-11, Organism=Drosophila melanogaster, GI21357041, Length=244, Percent_Identity=33.1967213114754, Blast_Score=121, Evalue=3e-28, Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=33.4677419354839, Blast_Score=121, Evalue=4e-28, Organism=Drosophila melanogaster, GI21355319, Length=238, Percent_Identity=31.5126050420168, Blast_Score=115, Evalue=2e-26, Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=31.7073170731707, Blast_Score=111, Evalue=4e-25, Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=29.3172690763052, Blast_Score=105, Evalue=2e-23, Organism=Drosophila melanogaster, GI24644337, Length=249, Percent_Identity=30.9236947791165, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=31.1475409836066, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=32.7935222672065, Blast_Score=94, Evalue=7e-20, Organism=Drosophila melanogaster, GI17737361, Length=251, Percent_Identity=29.8804780876494, Blast_Score=91, Evalue=9e-19, Organism=Drosophila melanogaster, GI24640492, Length=198, Percent_Identity=28.2828282828283, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI24580925, Length=202, Percent_Identity=28.7128712871287, Blast_Score=80, Evalue=8e-16, Organism=Drosophila melanogaster, GI21357673, Length=196, Percent_Identity=27.5510204081633, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI21355631, Length=171, Percent_Identity=28.6549707602339, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI28574402, Length=210, Percent_Identity=27.6190476190476, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24584744, Length=210, Percent_Identity=27.6190476190476, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI24584748, Length=208, Percent_Identity=25.9615384615385, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI161076933, Length=208, Percent_Identity=25.9615384615385, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI18859837, Length=189, Percent_Identity=32.2751322751323, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI21358495, Length=197, Percent_Identity=28.4263959390863, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI21356301, Length=181, Percent_Identity=25.9668508287293, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26017; Mature: 25886
Theoretical pI: Translated: 6.52; Mature: 6.52
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MARNLFDLTGKVALVTGGSRGLGFEMVKAFAENGADVIIASRKLDACEAAAEEVRKLGRK CCCCCHHCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHH AFAFAAHCGRWDDIDALIEASYGHFGRVDILVNNAGSGPRMASDEVTENLFDSVLNLNFK HHHHHHHCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCC GPFRLASQVAKRMADGDGGSIINISSSGSLVPLPHVVPYGSAKAAINAMSLSLAHEYAPK CHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCC VRVNTICPGPFLTDIAKAWPEQMRQSADNALGRPGYPEEIVTAALYLASPASSFTTGSLL EEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEE RVDGSAA EECCCCC >Mature Secondary Structure ARNLFDLTGKVALVTGGSRGLGFEMVKAFAENGADVIIASRKLDACEAAAEEVRKLGRK CCCCHHCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHH AFAFAAHCGRWDDIDALIEASYGHFGRVDILVNNAGSGPRMASDEVTENLFDSVLNLNFK HHHHHHHCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCC GPFRLASQVAKRMADGDGGSIINISSSGSLVPLPHVVPYGSAKAAINAMSLSLAHEYAPK CHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCC VRVNTICPGPFLTDIAKAWPEQMRQSADNALGRPGYPEEIVTAALYLASPASSFTTGSLL EEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEE RVDGSAA EECCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9784136 [H]