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The map label for this gene is sdaA [H]

Identifier: 114798834

GI number: 114798834

Start: 1941686

End: 1943062

Strand: Reverse

Name: sdaA [H]

Synonym: HNE_1878

Alternate gene names: 114798834

Gene position: 1943062-1941686 (Counterclockwise)

Preceding gene: 114799387

Following gene: 114800058

Centisome position: 52.44

GC content: 59.55

Gene sequence:

>1377_bases
ATGTTGTCGGTATTGGATATTTTTCGGGTTGGCATTGGGCCTTCGAGTTCGCACACGGTGGGTCCGATCCGCATTGCAAA
CCGGTTCATGGCGCATCTGGCCAGTTCGGAAAAGCTATCGCGAACGGCACGGATTGAGGCAGAGTTGCAGGGGTCACTCG
CGCTGACGGGTGTGGGGCACGCGACGCCCAAAGCCGTGGTGCTGGGTCTGCTGGGGCTCGACCCTGAAACGCTGGATGCG
GAGGAAGCAGACCGGCTGGTCGCGCAAGCGTATGAGCAGAAGGTGCTGCCATTGCCCGATGGCCGGAAGATGAAATTCGA
TCCGGAGACGGATATTCGGTTTGCCTATGATGTCATGCCAGACCTGCACCCGAACGGGCTTCGGATCAAGGCATATGACG
AAGGCGGCGAAGTGATTGCCGACGAGACGTGGTATTCCACGGGAGGCGGATTTATCGCGACGCGCAAACAGCTGGAAAAG
CCTGTCGAGGATGACATTCTGCCGGTGGGGGACCCTGTGCCGTTTGGTTTTACCTCGGCTGCTCAATTGCTGGAACTCTG
CCAGACAAATGGCCTCGGCATTTATGAGGTCATCCTGGCGAATGAAGACGCCAAACGGCCACGCGAGAAAACAGAAGCCG
CGCTGGACCGGATTGCGGCGGTGATGATGGCTTGCATTGATCGTGGATTGATGCGGAAGGGGGAGCTGCCGGGCGGCTTG
AAGGTTCGCCGCCGCGCCCCGGAGATCTGGCAGAAATTGCAGGAGGGCCCGCCCTCCAATGAGCGCGAGCAGTTGTTCGA
TTGGCTGAATGTTTATGCCATGGCTGTGAATGAAGAAAACGCTGCGGGCGGGCAGGTGGTGACGGCGCCAACAAATGGCG
CGGCCGGTATCATACCGTCCGTAATCCGGCATTATTGTGCCGATACCGAAGACGCGCCGGAGCGTATGCGGAAGTTTCTG
CTGACCGCCGGCGGGATTGGGCTGCTTTACAAGCAGCGGGCGTCAATTTCGGGCGCTGAGATGGGATGCCAGGGTGAGGT
GGGGGTCGCTTGCTCGATGGCGGCGGGCGGTCTTGCGGCGGTTTGGGGCGGCACGCCACAACAGGTGGCTAATGCGGCGG
AGATCGGGATGGAGCACAATCTGGGGCTTACCTGCGATCCTGTAGGCGGCCTTGTGCAAATTCCCTGTATTGAGCGGAAC
GCGATTGGCGCCGTGAAAGCGGCCAATGCTGCCCGCCTGGCGCTGCATTCCCTCGAACAGACGAAAGTCTCTCTGGATCA
GGTTATCGAGACGATGCGGCAGACCGGATTGGACATGTCATCCAAATATAAGGAGACCAGCCAGGGCGGTCTCGCGGTCA
ATGTGATCGAATGCTAG

Upstream 100 bases:

>100_bases
TGGCCTTGATGTGACGGAGCCTGACTGACGCGGGTTGCGGGGGCGGGCTAATTCGGTCACCACTTTGAAAAGTGTTACGC
AGAGGAAACGGCCCCTTCAG

Downstream 100 bases:

>100_bases
TGCATTGACACAAAACATTATCACAGCCGACACCGAAGTGTAGCGGAACCGCAGTAGCGCTGCATCCTGTATGACAGGGG
CAGCGGACAAAATGCACGAT

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MLSVLDIFRVGIGPSSSHTVGPIRIANRFMAHLASSEKLSRTARIEAELQGSLALTGVGHATPKAVVLGLLGLDPETLDA
EEADRLVAQAYEQKVLPLPDGRKMKFDPETDIRFAYDVMPDLHPNGLRIKAYDEGGEVIADETWYSTGGGFIATRKQLEK
PVEDDILPVGDPVPFGFTSAAQLLELCQTNGLGIYEVILANEDAKRPREKTEAALDRIAAVMMACIDRGLMRKGELPGGL
KVRRRAPEIWQKLQEGPPSNEREQLFDWLNVYAMAVNEENAAGGQVVTAPTNGAAGIIPSVIRHYCADTEDAPERMRKFL
LTAGGIGLLYKQRASISGAEMGCQGEVGVACSMAAGGLAAVWGGTPQQVANAAEIGMEHNLGLTCDPVGGLVQIPCIERN
AIGAVKAANAARLALHSLEQTKVSLDQVIETMRQTGLDMSSKYKETSQGGLAVNVIEC

Sequences:

>Translated_458_residues
MLSVLDIFRVGIGPSSSHTVGPIRIANRFMAHLASSEKLSRTARIEAELQGSLALTGVGHATPKAVVLGLLGLDPETLDA
EEADRLVAQAYEQKVLPLPDGRKMKFDPETDIRFAYDVMPDLHPNGLRIKAYDEGGEVIADETWYSTGGGFIATRKQLEK
PVEDDILPVGDPVPFGFTSAAQLLELCQTNGLGIYEVILANEDAKRPREKTEAALDRIAAVMMACIDRGLMRKGELPGGL
KVRRRAPEIWQKLQEGPPSNEREQLFDWLNVYAMAVNEENAAGGQVVTAPTNGAAGIIPSVIRHYCADTEDAPERMRKFL
LTAGGIGLLYKQRASISGAEMGCQGEVGVACSMAAGGLAAVWGGTPQQVANAAEIGMEHNLGLTCDPVGGLVQIPCIERN
AIGAVKAANAARLALHSLEQTKVSLDQVIETMRQTGLDMSSKYKETSQGGLAVNVIEC
>Mature_458_residues
MLSVLDIFRVGIGPSSSHTVGPIRIANRFMAHLASSEKLSRTARIEAELQGSLALTGVGHATPKAVVLGLLGLDPETLDA
EEADRLVAQAYEQKVLPLPDGRKMKFDPETDIRFAYDVMPDLHPNGLRIKAYDEGGEVIADETWYSTGGGFIATRKQLEK
PVEDDILPVGDPVPFGFTSAAQLLELCQTNGLGIYEVILANEDAKRPREKTEAALDRIAAVMMACIDRGLMRKGELPGGL
KVRRRAPEIWQKLQEGPPSNEREQLFDWLNVYAMAVNEENAAGGQVVTAPTNGAAGIIPSVIRHYCADTEDAPERMRKFL
LTAGGIGLLYKQRASISGAEMGCQGEVGVACSMAAGGLAAVWGGTPQQVANAAEIGMEHNLGLTCDPVGGLVQIPCIERN
AIGAVKAANAARLALHSLEQTKVSLDQVIETMRQTGLDMSSKYKETSQGGLAVNVIEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=458, Percent_Identity=48.2532751091703, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI48994925, Length=461, Percent_Identity=49.8915401301518, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1789161, Length=461, Percent_Identity=47.5054229934924, Blast_Score=405, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49025; Mature: 49025

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVLDIFRVGIGPSSSHTVGPIRIANRFMAHLASSEKLSRTARIEAELQGSLALTGVGH
CCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEECCC
ATPKAVVLGLLGLDPETLDAEEADRLVAQAYEQKVLPLPDGRKMKFDPETDIRFAYDVMP
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCEEEEECCC
DLHPNGLRIKAYDEGGEVIADETWYSTGGGFIATRKQLEKPVEDDILPVGDPVPFGFTSA
CCCCCCEEEEEECCCCCEEECCCEECCCCCCCEEHHHHCCCHHHCCCCCCCCCCCCHHHH
AQLLELCQTNGLGIYEVILANEDAKRPREKTEAALDRIAAVMMACIDRGLMRKGELPGGL
HHHHHHHHCCCCCEEEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
KVRRRAPEIWQKLQEGPPSNEREQLFDWLNVYAMAVNEENAAGGQVVTAPTNGAAGIIPS
HHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCCCCCCCEEEECCCCCCCHHHHH
VIRHYCADTEDAPERMRKFLLTAGGIGLLYKQRASISGAEMGCQGEVGVACSMAAGGLAA
HHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEE
VWGGTPQQVANAAEIGMEHNLGLTCDPVGGLVQIPCIERNAIGAVKAANAARLALHSLEQ
ECCCCHHHHHHHHHHCCCCCCCEEECCCCCEEECCEECCCCCCHHHHCCHHHHHHHHHHH
TKVSLDQVIETMRQTGLDMSSKYKETSQGGLAVNVIEC
HHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure
MLSVLDIFRVGIGPSSSHTVGPIRIANRFMAHLASSEKLSRTARIEAELQGSLALTGVGH
CCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEECCC
ATPKAVVLGLLGLDPETLDAEEADRLVAQAYEQKVLPLPDGRKMKFDPETDIRFAYDVMP
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCEEEEECCC
DLHPNGLRIKAYDEGGEVIADETWYSTGGGFIATRKQLEKPVEDDILPVGDPVPFGFTSA
CCCCCCEEEEEECCCCCEEECCCEECCCCCCCEEHHHHCCCHHHCCCCCCCCCCCCHHHH
AQLLELCQTNGLGIYEVILANEDAKRPREKTEAALDRIAAVMMACIDRGLMRKGELPGGL
HHHHHHHHCCCCCEEEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
KVRRRAPEIWQKLQEGPPSNEREQLFDWLNVYAMAVNEENAAGGQVVTAPTNGAAGIIPS
HHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCCCCCCCEEEECCCCCCCHHHHH
VIRHYCADTEDAPERMRKFLLTAGGIGLLYKQRASISGAEMGCQGEVGVACSMAAGGLAA
HHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEE
VWGGTPQQVANAAEIGMEHNLGLTCDPVGGLVQIPCIERNAIGAVKAANAARLALHSLEQ
ECCCCHHHHHHHHHHCCCCCCCEEECCCCCEEECCEECCCCCCHHHHCCHHHHHHHHHHH
TKVSLDQVIETMRQTGLDMSSKYKETSQGGLAVNVIEC
HHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]