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The map label for this gene is pnuC [H]

Identifier: 114798743

GI number: 114798743

Start: 1184459

End: 1185115

Strand: Reverse

Name: pnuC [H]

Synonym: HNE_1176

Alternate gene names: 114798743

Gene position: 1185115-1184459 (Counterclockwise)

Preceding gene: 114799491

Following gene: 114797512

Centisome position: 31.99

GC content: 63.01

Gene sequence:

>657_bases
ATGACCGCATCAGCCGCCCCCCGCCGCCCCGGCACGGCCCTCATCGCCGGTCTCTTCCTCATCTCCGCGACCATCGCAGC
CGCCGCCTGGTACACCGGCGCGGCGAGCTACCTCGAAGCCATCGCCTTCGTCACCGGCGTCTTCTGCGTCTGGCTGGTCA
CCCGCCAGAACATCTGGAACTTCCCCCTCGGCCTGATCACAGTCGGCATCTACGCCGTTGTCTTCTACCTGTCCGACCTC
TTCGCCATGGCCGGGCTCCAGCTCGTCTTCTTCGCCATAAATCTCGTCGGCTGGTATCTCTGGCTCTATGGCGGCGAAAA
CCGCAGCGCCCTGAAAATCCGCCGCGCGCCCCGCCTCGAATGGGCGCTCACCCTCCTCGGTATTGCAGGCGGCACAGCCC
TTCTCTACCGCCTGCTGGATGAAGCCGGCGGGGCCACCAAATTCTGGGACGCCCTCGTCACCTCCATCAGCCTCGCCGCC
CAATGGGCCCAGAGCCGGAAAATCTTCGAATGCTGGTGGCTGTGGATCATTGCCGACATTATCTACATCCCCGTCTGCCT
GTTTAACGGCCTTTACCTGACGGCCCTTCTGTATGCGGTGTTTCTGGCGCTCTCAGTCATGGGCCTGCTGGAATGGCGCA
AATCGGTGAATGCATGA

Upstream 100 bases:

>100_bases
AACCTCGAAATCGAGATGGGCAAAGCGTAACGCACATACAGGTCAGGCCCCTCCCCAAAGGAGGGGCCTCTCCACCAGGC
ACCCAGGGAAGGCGCATTAG

Downstream 100 bases:

>100_bases
CCTGCAACAAACCCCTGCGCGTCGTCCTGATCGGCGCCGAATCCACCGGCAAGACCACGCTCTGCATCGAGCTGGCCGCC
CATTACAACACCGTCTGGGT

Product: nicotinamide mononucleotide transporter PnuC

Products: nicotinamide nucleotide [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTASAAPRRPGTALIAGLFLISATIAAAAWYTGAASYLEAIAFVTGVFCVWLVTRQNIWNFPLGLITVGIYAVVFYLSDL
FAMAGLQLVFFAINLVGWYLWLYGGENRSALKIRRAPRLEWALTLLGIAGGTALLYRLLDEAGGATKFWDALVTSISLAA
QWAQSRKIFECWWLWIIADIIYIPVCLFNGLYLTALLYAVFLALSVMGLLEWRKSVNA

Sequences:

>Translated_218_residues
MTASAAPRRPGTALIAGLFLISATIAAAAWYTGAASYLEAIAFVTGVFCVWLVTRQNIWNFPLGLITVGIYAVVFYLSDL
FAMAGLQLVFFAINLVGWYLWLYGGENRSALKIRRAPRLEWALTLLGIAGGTALLYRLLDEAGGATKFWDALVTSISLAA
QWAQSRKIFECWWLWIIADIIYIPVCLFNGLYLTALLYAVFLALSVMGLLEWRKSVNA
>Mature_217_residues
TASAAPRRPGTALIAGLFLISATIAAAAWYTGAASYLEAIAFVTGVFCVWLVTRQNIWNFPLGLITVGIYAVVFYLSDLF
AMAGLQLVFFAINLVGWYLWLYGGENRSALKIRRAPRLEWALTLLGIAGGTALLYRLLDEAGGATKFWDALVTSISLAAQ
WAQSRKIFECWWLWIIADIIYIPVCLFNGLYLTALLYAVFLALSVMGLLEWRKSVNA

Specific function: Required for nicotinamide riboside transport across the inner membrane [H]

COG id: COG3201

COG function: function code H; Nicotinamide mononucleotide transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786965, Length=206, Percent_Identity=30.0970873786408, Blast_Score=70, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006419 [H]

Pfam domain/function: PF04973 NMN_transporter [H]

EC number: NA

Molecular weight: Translated: 24089; Mature: 23958

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASAAPRRPGTALIAGLFLISATIAAAAWYTGAASYLEAIAFVTGVFCVWLVTRQNIWN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FPLGLITVGIYAVVFYLSDLFAMAGLQLVFFAINLVGWYLWLYGGENRSALKIRRAPRLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHH
WALTLLGIAGGTALLYRLLDEAGGATKFWDALVTSISLAAQWAQSRKIFECWWLWIIADI
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
IYIPVCLFNGLYLTALLYAVFLALSVMGLLEWRKSVNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TASAAPRRPGTALIAGLFLISATIAAAAWYTGAASYLEAIAFVTGVFCVWLVTRQNIWN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FPLGLITVGIYAVVFYLSDLFAMAGLQLVFFAINLVGWYLWLYGGENRSALKIRRAPRLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHH
WALTLLGIAGGTALLYRLLDEAGGATKFWDALVTSISLAAQWAQSRKIFECWWLWIIADI
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
IYIPVCLFNGLYLTALLYAVFLALSVMGLLEWRKSVNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide [Periplasm] [C]

Specific reaction: nicotinamide nucleotide [Periplasm] = nicotinamide nucleotide [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2198247; 11677609 [H]