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The map label for this gene is cdd [H]

Identifier: 114798713

GI number: 114798713

Start: 1327938

End: 1328333

Strand: Direct

Name: cdd [H]

Synonym: HNE_1295

Alternate gene names: 114798713

Gene position: 1327938-1328333 (Clockwise)

Preceding gene: 114797261

Following gene: 114799075

Centisome position: 35.84

GC content: 69.19

Gene sequence:

>396_bases
ATGAGCATCGACTGGGACGCGCTGAAGGCTGCCGCGCGGGAGATGCAGGCGCGGGCGTATGTGCCGTATTCGGAGTATCG
GGTCGGGGCGGCGCTGCTCACGGCCGATGGCACGGTGGTGACCGGGTGTAATGTCGAGAATGCGTCTTTCGGGGCGACGT
GCTGCGCGGAGCGGACGGCGGTGTTTACGGCGGTGGCGGCAGGGCACCGGGACTTCCGGGCGATTGCGGTGGCCACAAAC
GGGGCGGACGCGGGCACGCCGTGCGGGATCTGCCGGCAGGTCCTGGCGGAGTTTTCCGCCGATGGCGCGCTGGAAGTGGT
GTGCTTTACGCCGGAGGGGGCAGAGGCGCGCTACACGCTGGCGGAATTGCTGCCGCATGCGTTCAGGCTGGGCTAG

Upstream 100 bases:

>100_bases
GGATCGAGACGCTGGAACGGCTGAGCGAAGATGGCGGGGCCGCGCTGCACAGCCGCAAGCTGCGCGCGTTTGATGAGCCG
CCGTTTAGATGAGCGGGCAG

Downstream 100 bases:

>100_bases
GCGCTTGCCCCGGCGTTAGCGGGGGGCGACACGGGATTGTCACTGGACGAGTGGGGAGGGGCGCGTTACCTCCCTTGTAT
GACGATGACACGACCGCGAC

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 131; Mature: 130

Protein sequence:

>131_residues
MSIDWDALKAAAREMQARAYVPYSEYRVGAALLTADGTVVTGCNVENASFGATCCAERTAVFTAVAAGHRDFRAIAVATN
GADAGTPCGICRQVLAEFSADGALEVVCFTPEGAEARYTLAELLPHAFRLG

Sequences:

>Translated_131_residues
MSIDWDALKAAAREMQARAYVPYSEYRVGAALLTADGTVVTGCNVENASFGATCCAERTAVFTAVAAGHRDFRAIAVATN
GADAGTPCGICRQVLAEFSADGALEVVCFTPEGAEARYTLAELLPHAFRLG
>Mature_130_residues
SIDWDALKAAAREMQARAYVPYSEYRVGAALLTADGTVVTGCNVENASFGATCCAERTAVFTAVAAGHRDFRAIAVATNG
ADAGTPCGICRQVLAEFSADGALEVVCFTPEGAEARYTLAELLPHAFRLG

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=122, Percent_Identity=45.0819672131148, Blast_Score=108, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17540514, Length=118, Percent_Identity=50.8474576271186, Blast_Score=111, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17551074, Length=112, Percent_Identity=48.2142857142857, Blast_Score=102, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6323274, Length=126, Percent_Identity=38.8888888888889, Blast_Score=92, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24582741, Length=123, Percent_Identity=43.9024390243902, Blast_Score=99, Evalue=9e-22,
Organism=Drosophila melanogaster, GI19920920, Length=94, Percent_Identity=50, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24582744, Length=124, Percent_Identity=37.9032258064516, Blast_Score=76, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 13695; Mature: 13563

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDWDALKAAAREMQARAYVPYSEYRVGAALLTADGTVVTGCNVENASFGATCCAERTA
CCCCHHHHHHHHHHHHHHCCCCHHHHCCCEEEEECCCCEEECCCCCCCCCCCHHHHHHHH
VFTAVAAGHRDFRAIAVATNGADAGTPCGICRQVLAEFSADGALEVVCFTPEGAEARYTL
HHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHH
AELLPHAFRLG
HHHHHHHHCCC
>Mature Secondary Structure 
SIDWDALKAAAREMQARAYVPYSEYRVGAALLTADGTVVTGCNVENASFGATCCAERTA
CCCHHHHHHHHHHHHHHCCCCHHHHCCCEEEEECCCCEEECCCCCCCCCCCHHHHHHHH
VFTAVAAGHRDFRAIAVATNGADAGTPCGICRQVLAEFSADGALEVVCFTPEGAEARYTL
HHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHH
AELLPHAFRLG
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]