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The map label for this gene is steT [H]

Identifier: 114798685

GI number: 114798685

Start: 1374767

End: 1376086

Strand: Direct

Name: steT [H]

Synonym: HNE_1338

Alternate gene names: 114798685

Gene position: 1374767-1376086 (Clockwise)

Preceding gene: 114799350

Following gene: 114797504

Centisome position: 37.11

GC content: 66.82

Gene sequence:

>1320_bases
GTGACCGAACCTTCCGCCTATCCCGTCCGTAGCCTGACGACGCGCTATGTTGTGGTGGTGACGATTGCGATGGTGATCGG
GGCGGGGATATTCAAATCTCCGGCGCTGGTGGCGGCCAATGCAGGGTCGGAGACGGCGGTGTATCTGCTGTGGCTGGCGG
GCGGATTTATCTCGCTGATGGGGGCGCTGTGCTATTCAGAGCTGGCGGCGGCGTTTCCCCATGCGGGCGGGGATTATCAT
TTCCTGGAGCGGGCCTGGGGGCGGCGCTTTGCGTTTCTGTTTGCGTGGGCGCGCTTTGCGGTGATCAATACCGGCGCGAT
TGCGCTGCTCGGCTTTGTCATCGGCGATTATATGAACCGCGTGATCGATCTGGGGGCGCATGGCCCGGCGATCTATGCCT
TTGCCAGCGTGCTGGGGCTGAGCGCGCTGAAGCTGCGGCCGACGGGCGAGGCGGGCGATAGCGGGCTGGTGATCATTCTT
GTGGTGGGGCTGCTGGTGCTGGTGGCGGCGGGGGCGAAGATTGCGCTGTCGGGCACGCCGCCGCTCGCGCCGGGCGCGCC
CTACATGCCGGGCTTTGGCGGCATCGGCTACGGCCTCGTCTTTGTGTTGCTGGCCTTTGGCGGGTGGACGGAATCGGCGA
CGCTTTCCTCTGAAGTGAAGGATGGCGAGCGGGGCATGGTGCGCGCGCTCGTCATCGCGATTTCGCTCATCACGGGGCTT
TACCTGCTGACGGCCTGGGCGATGCTGCGCGGGCTGGGGCTCGATGGCCTGGCGGGGGCGGATGCGCCGGCGGCGGATCT
GATGGCGCTGGCGTTTGGGGAAAGCGCCGGTGTGGTGCTGGCCCTCGCGGTGGTCGCGGCGGCGGTGACCTCTGTGAACG
CCACGATCATCGTGGGGGCGCGCACCACCTATGCGGCGGCCGCGCGCCTGCCGGCCCTGTCGTGGCTTGGCCGCTGGAAC
GAAACCACGCGCAGCCCGCGCAACGCCATTCTGGCGCAGGGGGCGATCTCGCTGGCGCTGGTTGGATTTGGCGCGGCGTA
TCGCGGGTTTGAAACGCTGGTGGATTATACGGCGCCGGTTTACTGGGTGTTCCTGATTGCCAGTGGGATGGCGCTGATCC
GCTTGCGGATGAAGGAGCCTGCGGCGGCGCGACCTTTCCGTGTGCCGCTTTATCCGCTGGTTCCGGCGCTGTTCATTCTC
TCGAGCGGCGCGATGCTGGTTTCGGCCATTCTTTATGTGCAGGGCGGGGCGTTCTTCGGGCTCGGCGTGCTGGTGGCGGG
GCTGGCGCTGCTGCCGGTTCTGGGGCGCAGCGGCAGATAA

Upstream 100 bases:

>100_bases
GGAGGGCGGGCCGTCTGGTCCGCCCTTTTTCTTTGCGCCGATGTCGCCGGGGGCAATCTTCGTGTAAGCGGGAAGGCGAA
TTGACCGGGGCGCCCAGATT

Downstream 100 bases:

>100_bases
TCCGGAACCCTGCGCTGGCCCCCGCGTTGGTTTTGCAAGTGACCGCCACAAAGGCGGCATGATGCCAAATCGGGAGGCCC
TCCATGAGCAACTCCAAGAA

Product: amino acid permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MTEPSAYPVRSLTTRYVVVVTIAMVIGAGIFKSPALVAANAGSETAVYLLWLAGGFISLMGALCYSELAAAFPHAGGDYH
FLERAWGRRFAFLFAWARFAVINTGAIALLGFVIGDYMNRVIDLGAHGPAIYAFASVLGLSALKLRPTGEAGDSGLVIIL
VVGLLVLVAAGAKIALSGTPPLAPGAPYMPGFGGIGYGLVFVLLAFGGWTESATLSSEVKDGERGMVRALVIAISLITGL
YLLTAWAMLRGLGLDGLAGADAPAADLMALAFGESAGVVLALAVVAAAVTSVNATIIVGARTTYAAAARLPALSWLGRWN
ETTRSPRNAILAQGAISLALVGFGAAYRGFETLVDYTAPVYWVFLIASGMALIRLRMKEPAAARPFRVPLYPLVPALFIL
SSGAMLVSAILYVQGGAFFGLGVLVAGLALLPVLGRSGR

Sequences:

>Translated_439_residues
MTEPSAYPVRSLTTRYVVVVTIAMVIGAGIFKSPALVAANAGSETAVYLLWLAGGFISLMGALCYSELAAAFPHAGGDYH
FLERAWGRRFAFLFAWARFAVINTGAIALLGFVIGDYMNRVIDLGAHGPAIYAFASVLGLSALKLRPTGEAGDSGLVIIL
VVGLLVLVAAGAKIALSGTPPLAPGAPYMPGFGGIGYGLVFVLLAFGGWTESATLSSEVKDGERGMVRALVIAISLITGL
YLLTAWAMLRGLGLDGLAGADAPAADLMALAFGESAGVVLALAVVAAAVTSVNATIIVGARTTYAAAARLPALSWLGRWN
ETTRSPRNAILAQGAISLALVGFGAAYRGFETLVDYTAPVYWVFLIASGMALIRLRMKEPAAARPFRVPLYPLVPALFIL
SSGAMLVSAILYVQGGAFFGLGVLVAGLALLPVLGRSGR
>Mature_438_residues
TEPSAYPVRSLTTRYVVVVTIAMVIGAGIFKSPALVAANAGSETAVYLLWLAGGFISLMGALCYSELAAAFPHAGGDYHF
LERAWGRRFAFLFAWARFAVINTGAIALLGFVIGDYMNRVIDLGAHGPAIYAFASVLGLSALKLRPTGEAGDSGLVIILV
VGLLVLVAAGAKIALSGTPPLAPGAPYMPGFGGIGYGLVFVLLAFGGWTESATLSSEVKDGERGMVRALVIAISLITGLY
LLTAWAMLRGLGLDGLAGADAPAADLMALAFGESAGVVLALAVVAAAVTSVNATIIVGARTTYAAAARLPALSWLGRWNE
TTRSPRNAILAQGAISLALVGFGAAYRGFETLVDYTAPVYWVFLIASGMALIRLRMKEPAAARPFRVPLYPLVPALFILS
SGAMLVSAILYVQGGAFFGLGVLVAGLALLPVLGRSGR

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI187423910, Length=414, Percent_Identity=24.8792270531401, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI7657591, Length=414, Percent_Identity=24.8792270531401, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI115648063, Length=427, Percent_Identity=22.9508196721311, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI115648022, Length=427, Percent_Identity=22.9508196721311, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI33286428, Length=398, Percent_Identity=25.1256281407035, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI186910308, Length=430, Percent_Identity=23.953488372093, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI186910306, Length=430, Percent_Identity=23.953488372093, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI186910304, Length=430, Percent_Identity=23.953488372093, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI71979932, Length=405, Percent_Identity=22.7160493827161, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI7657683, Length=384, Percent_Identity=23.1770833333333, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI9790235, Length=348, Percent_Identity=21.8390804597701, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI87082250, Length=342, Percent_Identity=24.2690058479532, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17540018, Length=440, Percent_Identity=26.5909090909091, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI32566699, Length=379, Percent_Identity=25.3298153034301, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71982612, Length=443, Percent_Identity=27.313769751693, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71982608, Length=443, Percent_Identity=27.313769751693, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71995388, Length=439, Percent_Identity=24.8291571753986, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71995382, Length=439, Percent_Identity=24.8291571753986, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17568033, Length=400, Percent_Identity=23, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71993915, Length=437, Percent_Identity=24.9427917620137, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357367, Length=435, Percent_Identity=24.367816091954, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI221331183, Length=404, Percent_Identity=27.4752475247525, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17647653, Length=404, Percent_Identity=27.4752475247525, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24664379, Length=404, Percent_Identity=27.4752475247525, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI45550968, Length=438, Percent_Identity=26.027397260274, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI19921172, Length=438, Percent_Identity=26.027397260274, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24641993, Length=384, Percent_Identity=24.7395833333333, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24641995, Length=384, Percent_Identity=24.7395833333333, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24651635, Length=384, Percent_Identity=23.1770833333333, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24651633, Length=384, Percent_Identity=23.1770833333333, Blast_Score=94, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 45385; Mature: 45254

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPSAYPVRSLTTRYVVVVTIAMVIGAGIFKSPALVAANAGSETAVYLLWLAGGFISLM
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEECCCCCHHHHHHHHHHHHHHHH
GALCYSELAAAFPHAGGDYHFLERAWGRRFAFLFAWARFAVINTGAIALLGFVIGDYMNR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VIDLGAHGPAIYAFASVLGLSALKLRPTGEAGDSGLVIILVVGLLVLVAAGAKIALSGTP
HHHCCCCCHHHHHHHHHHCCHHEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCC
PLAPGAPYMPGFGGIGYGLVFVLLAFGGWTESATLSSEVKDGERGMVRALVIAISLITGL
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHH
YLLTAWAMLRGLGLDGLAGADAPAADLMALAFGESAGVVLALAVVAAAVTSVNATIIVGA
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEEC
RTTYAAAARLPALSWLGRWNETTRSPRNAILAQGAISLALVGFGAAYRGFETLVDYTAPV
CHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YWVFLIASGMALIRLRMKEPAAARPFRVPLYPLVPALFILSSGAMLVSAILYVQGGAFFG
HHHHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHH
LGVLVAGLALLPVLGRSGR
HHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TEPSAYPVRSLTTRYVVVVTIAMVIGAGIFKSPALVAANAGSETAVYLLWLAGGFISLM
CCCCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEECCCCCHHHHHHHHHHHHHHHH
GALCYSELAAAFPHAGGDYHFLERAWGRRFAFLFAWARFAVINTGAIALLGFVIGDYMNR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VIDLGAHGPAIYAFASVLGLSALKLRPTGEAGDSGLVIILVVGLLVLVAAGAKIALSGTP
HHHCCCCCHHHHHHHHHHCCHHEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCC
PLAPGAPYMPGFGGIGYGLVFVLLAFGGWTESATLSSEVKDGERGMVRALVIAISLITGL
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHH
YLLTAWAMLRGLGLDGLAGADAPAADLMALAFGESAGVVLALAVVAAAVTSVNATIIVGA
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEEC
RTTYAAAARLPALSWLGRWNETTRSPRNAILAQGAISLALVGFGAAYRGFETLVDYTAPV
CHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YWVFLIASGMALIRLRMKEPAAARPFRVPLYPLVPALFILSSGAMLVSAILYVQGGAFFG
HHHHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHH
LGVLVAGLALLPVLGRSGR
HHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]