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The map label for this gene is pgi [H]

Identifier: 114798439

GI number: 114798439

Start: 1774739

End: 1776289

Strand: Reverse

Name: pgi [H]

Synonym: HNE_1733

Alternate gene names: 114798439

Gene position: 1776289-1774739 (Counterclockwise)

Preceding gene: 114800212

Following gene: 114797667

Centisome position: 47.94

GC content: 62.73

Gene sequence:

>1551_bases
ATGCGTAACGAACTCAAAGTGCACGCCGCCCGCCTGAGTCGGCAGCCCCTGAAGGCTCTTTCAGCCGCGCGTGCCGGCAC
CGAGCCCCTGTCCGCAGCGGGCTGGAAAATCAGCCTGGCGCGGCATTTCCTCGACACTGAAGCGGAGCAAAGCCTGCTCG
ACTTTGGCGCCGAGGCCCGGCTGACAAAGGCCGCAGAGGCCCTCTTTGGCGAAGCCATTGTGAACCCGTCTGAGGGCCGC
CCGGCCCTGCACTGGGCATTGCGCGCGCCCGCCCGCCTGATGGGCGAAGCAGAAAGTGTCCGGCAGAGCGTCATCGACGC
GCTTGAATTTGCAGGGAAAGTTCAAACCGGCGAAGTGCGCACGGCCGGCGGCGAAGCCTTCACCGCAGTCTTGCACATCG
GCATTGGCGGATCGGATTTCGGGCCACGGCTGATTGCGGATGCCTTCGAAGACCTCGCCCACCCCGCCATCAAGCTGCGC
TTTGCGGCGAACGTAGACCCTTATGATCTCGACCGCGCCATGGCGGGGCTGAAACCCGAGAACACGCTGGTGGTAGGCGT
TTCCAAATCCTTCGGCACCGAAGAAACCCTTTATAATCTGGGGCGTGCGCGCCGGTGGCTGGAGGAAAAGCTGGGAGATG
ATGCCAGCAAGCATCTGGCCTTAGTGACGGCCAATCCGGACAAGGCCAAAGCCTGGCTTGGCGGGCGCGCGGCCTACACC
TTCGACATGCCAATCTCCGTCGGAGGGCGATTTTCGCTCTGGTCGGCGGCGTCGCTGGCCTGCATGATTTATCTGGGGCC
TGAGAATTTCCGGAGCATTCTCAATGGCGCCAATGAGATGGATGAACATGTACGTACGGCGCCGCTGGCGCAGAATGCCG
CGATGCGGCTGGCGCTGCTCGATTTCTGGAATACCTCGATCCGCGAGAAGCCGATGCGGGTGTTGCTGGCCTACGCCAAC
CGCCTGCGGCTGCTGCCGACATATCTGCAACAGCTGGAGATGGAATCGAACGGAAAGTCCGTTGATTCCCAAGGCAATTC
GGTGGCTCCGCCTACGGCGCCAGCCCTCTGGGGCGGCGAAGGATCTGTGGGTCAGCACTCCTATCACCAGTGGCTGCATC
AAGGGTCGCAGGATGTGCCCTGCGAGTTCATCCTGGCGCCTGACTACAACAGAGATTCTGAGGGGCTCGACGCGCTGACC
GCCCATGCATTGGCACAAGCCGAAGTGCTCGCGAACGGCCGTAGCATCGCGGAAGTACGCGCTGAGGAGCCGGGGATAAG
CGACGCGGTCGCCCCGCAGAAAGTGCATGCCGGCGGGCGGCCTTCCACCCTCTTTTCCCACGCCAGTTTCGGTCCTGAGG
CGTTTGGCGCGCTGGTGGCGCTGTATGAACACCGCACATATTTTGCGGGACAGCTGTGGGGCCTCAACCCCTTCGACCAG
TGGGGCGTGGAGCGTGGCAAGACGATGGCCGGGCGCATCAAGGCGGTGTTGAAAACCCCTGAGATTGCCGCCGATCCTGT
AACGGCTGCGCTGCTCAAGCAGATTTTCTGA

Upstream 100 bases:

>100_bases
GCGGGGTTTTGCGGGGGAAAGCTCCGCCTCTGCAGGCCTTGCGAAGCCAAACGACGCAGCCGATAAGCAGCCGGTCTGCC
TTTAGGGAATTGAGGACCGA

Downstream 100 bases:

>100_bases
GCGGATGACAGTTGCCCGGTTCTTGCGAGAAGCCACGCTGGGCGAGACCCGTTGGGCGGCGCTCGATTTGCAGGACAGGC
CGCTCGCGCTCTATATTGAA

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MRNELKVHAARLSRQPLKALSAARAGTEPLSAAGWKISLARHFLDTEAEQSLLDFGAEARLTKAAEALFGEAIVNPSEGR
PALHWALRAPARLMGEAESVRQSVIDALEFAGKVQTGEVRTAGGEAFTAVLHIGIGGSDFGPRLIADAFEDLAHPAIKLR
FAANVDPYDLDRAMAGLKPENTLVVGVSKSFGTEETLYNLGRARRWLEEKLGDDASKHLALVTANPDKAKAWLGGRAAYT
FDMPISVGGRFSLWSAASLACMIYLGPENFRSILNGANEMDEHVRTAPLAQNAAMRLALLDFWNTSIREKPMRVLLAYAN
RLRLLPTYLQQLEMESNGKSVDSQGNSVAPPTAPALWGGEGSVGQHSYHQWLHQGSQDVPCEFILAPDYNRDSEGLDALT
AHALAQAEVLANGRSIAEVRAEEPGISDAVAPQKVHAGGRPSTLFSHASFGPEAFGALVALYEHRTYFAGQLWGLNPFDQ
WGVERGKTMAGRIKAVLKTPEIAADPVTAALLKQIF

Sequences:

>Translated_516_residues
MRNELKVHAARLSRQPLKALSAARAGTEPLSAAGWKISLARHFLDTEAEQSLLDFGAEARLTKAAEALFGEAIVNPSEGR
PALHWALRAPARLMGEAESVRQSVIDALEFAGKVQTGEVRTAGGEAFTAVLHIGIGGSDFGPRLIADAFEDLAHPAIKLR
FAANVDPYDLDRAMAGLKPENTLVVGVSKSFGTEETLYNLGRARRWLEEKLGDDASKHLALVTANPDKAKAWLGGRAAYT
FDMPISVGGRFSLWSAASLACMIYLGPENFRSILNGANEMDEHVRTAPLAQNAAMRLALLDFWNTSIREKPMRVLLAYAN
RLRLLPTYLQQLEMESNGKSVDSQGNSVAPPTAPALWGGEGSVGQHSYHQWLHQGSQDVPCEFILAPDYNRDSEGLDALT
AHALAQAEVLANGRSIAEVRAEEPGISDAVAPQKVHAGGRPSTLFSHASFGPEAFGALVALYEHRTYFAGQLWGLNPFDQ
WGVERGKTMAGRIKAVLKTPEIAADPVTAALLKQIF
>Mature_516_residues
MRNELKVHAARLSRQPLKALSAARAGTEPLSAAGWKISLARHFLDTEAEQSLLDFGAEARLTKAAEALFGEAIVNPSEGR
PALHWALRAPARLMGEAESVRQSVIDALEFAGKVQTGEVRTAGGEAFTAVLHIGIGGSDFGPRLIADAFEDLAHPAIKLR
FAANVDPYDLDRAMAGLKPENTLVVGVSKSFGTEETLYNLGRARRWLEEKLGDDASKHLALVTANPDKAKAWLGGRAAYT
FDMPISVGGRFSLWSAASLACMIYLGPENFRSILNGANEMDEHVRTAPLAQNAAMRLALLDFWNTSIREKPMRVLLAYAN
RLRLLPTYLQQLEMESNGKSVDSQGNSVAPPTAPALWGGEGSVGQHSYHQWLHQGSQDVPCEFILAPDYNRDSEGLDALT
AHALAQAEVLANGRSIAEVRAEEPGISDAVAPQKVHAGGRPSTLFSHASFGPEAFGALVALYEHRTYFAGQLWGLNPFDQ
WGVERGKTMAGRIKAVLKTPEIAADPVTAALLKQIF

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=478, Percent_Identity=33.4728033472803, Blast_Score=285, Evalue=6e-77,
Organism=Homo sapiens, GI296080693, Length=474, Percent_Identity=31.2236286919831, Blast_Score=247, Evalue=2e-65,
Organism=Escherichia coli, GI1790457, Length=495, Percent_Identity=35.3535353535354, Blast_Score=282, Evalue=4e-77,
Organism=Caenorhabditis elegans, GI71996708, Length=492, Percent_Identity=33.130081300813, Blast_Score=251, Evalue=8e-67,
Organism=Caenorhabditis elegans, GI71996703, Length=492, Percent_Identity=33.130081300813, Blast_Score=251, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6319673, Length=493, Percent_Identity=34.0770791075051, Blast_Score=268, Evalue=2e-72,
Organism=Drosophila melanogaster, GI24651916, Length=475, Percent_Identity=34.9473684210526, Blast_Score=276, Evalue=3e-74,
Organism=Drosophila melanogaster, GI24651914, Length=475, Percent_Identity=34.9473684210526, Blast_Score=276, Evalue=3e-74,
Organism=Drosophila melanogaster, GI17737445, Length=475, Percent_Identity=34.9473684210526, Blast_Score=276, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 55744; Mature: 55744

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNELKVHAARLSRQPLKALSAARAGTEPLSAAGWKISLARHFLDTEAEQSLLDFGAEAR
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHCCCHHH
LTKAAEALFGEAIVNPSEGRPALHWALRAPARLMGEAESVRQSVIDALEFAGKVQTGEVR
HHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCEE
TAGGEAFTAVLHIGIGGSDFGPRLIADAFEDLAHPAIKLRFAANVDPYDLDRAMAGLKPE
ECCCCEEEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCC
NTLVVGVSKSFGTEETLYNLGRARRWLEEKLGDDASKHLALVTANPDKAKAWLGGRAAYT
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHCEEEEECCCCHHHHHCCCCEEEE
FDMPISVGGRFSLWSAASLACMIYLGPENFRSILNGANEMDEHVRTAPLAQNAAMRLALL
EECCCCCCCCCCHHHHCCEEEEEEECHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHH
DFWNTSIREKPMRVLLAYANRLRLLPTYLQQLEMESNGKSVDSQGNSVAPPTAPALWGGE
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECCC
GSVGQHSYHQWLHQGSQDVPCEFILAPDYNRDSEGLDALTAHALAQAEVLANGRSIAEVR
CCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
AEEPGISDAVAPQKVHAGGRPSTLFSHASFGPEAFGALVALYEHRTYFAGQLWGLNPFDQ
CCCCCCCCCCCCHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCHHH
WGVERGKTMAGRIKAVLKTPEIAADPVTAALLKQIF
HHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MRNELKVHAARLSRQPLKALSAARAGTEPLSAAGWKISLARHFLDTEAEQSLLDFGAEAR
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHCCCHHH
LTKAAEALFGEAIVNPSEGRPALHWALRAPARLMGEAESVRQSVIDALEFAGKVQTGEVR
HHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCEE
TAGGEAFTAVLHIGIGGSDFGPRLIADAFEDLAHPAIKLRFAANVDPYDLDRAMAGLKPE
ECCCCEEEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCC
NTLVVGVSKSFGTEETLYNLGRARRWLEEKLGDDASKHLALVTANPDKAKAWLGGRAAYT
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHCEEEEECCCCHHHHHCCCCEEEE
FDMPISVGGRFSLWSAASLACMIYLGPENFRSILNGANEMDEHVRTAPLAQNAAMRLALL
EECCCCCCCCCCHHHHCCEEEEEEECHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHH
DFWNTSIREKPMRVLLAYANRLRLLPTYLQQLEMESNGKSVDSQGNSVAPPTAPALWGGE
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECCC
GSVGQHSYHQWLHQGSQDVPCEFILAPDYNRDSEGLDALTAHALAQAEVLANGRSIAEVR
CCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
AEEPGISDAVAPQKVHAGGRPSTLFSHASFGPEAFGALVALYEHRTYFAGQLWGLNPFDQ
CCCCCCCCCCCCHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCHHH
WGVERGKTMAGRIKAVLKTPEIAADPVTAALLKQIF
HHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA