Click here to switch to the map view.

The map label for this gene is divJ [H]

Identifier: 114798414

GI number: 114798414

Start: 754650

End: 756269

Strand: Direct

Name: divJ [H]

Synonym: HNE_0746

Alternate gene names: 114798414

Gene position: 754650-756269 (Clockwise)

Preceding gene: 114800191

Following gene: 114799583

Centisome position: 20.37

GC content: 66.36

Gene sequence:

>1620_bases
TTGGACCCCCGCATGTCGCAGAAGCGATTACAGTTTGTTCACGTTGCCTGGCTCGCTATGTGCGGCGGCAGCGGCCTTGC
GGGCCTGATCGCGGGTGCGCCTCTGTGGCCGTTGCTCGCGATTATGGTTACCGCGATCCTTCCCGGACTGGCTGGAATGG
CACTCCCGGCGGGTGATTCGCCCTGGCGGGGGCTTGTAGTAATTTCCTGGACCCTGATCGCGCTGGCGGGCCTGATTCTC
AGTGGCGGGGGCGGTTCGCCGTTAACCGTACTGCTTCTTGCCGCGCCGCTGGCAGGGCTTCTCGCTGGCGCGCGCCGGAT
GGCCGCTGAGGCGGGCGTGTTTGCTGCGCTGGCCCTGTTCATGGCGTTAGTGGCGGGCGGTCTGGGCTGGTTACCGGCGC
CCGCCCCCTGGGCTGGCGCCTTGTCCGTCCCGTTCGCCTTCTCCGGACTCGTCGTATCGGCACTGATGATCTGGATGCTG
GTCCATTCCGGAATGGCGGAAAAACTCCAACCGGTCCTCGAGCGTAGTGAGCGCCTCCCGCCGGAGAACTCCAGCCAGAC
AGCTCCTACAGCCCCTATACGCGCGCCTCTGCCCCAGATGCCTGAAGCGGGCGTTGCGTTGCTCGACGTGACCCTTGAGG
GACGCTTGCGGGCCGTCGCGGGCGACAGCTTCGCCCTCCCTGCATTCCGCCCCGGCGCCGCGCTTGCTGCATTGTTCGCG
CCGGACGGCCTGCCGGAAAATTTCGGCATTGCCGATGGGCGGGTGACGGGCGAGGCCACCCTGGTGTCCGGTCAGAGGGT
TTTGATAACGGCAGAGACAGGCTCAGCTGGCTCTGCAATCGTTCTGTTTGCGCCGCCGGAGACCGTGGCCGACCCCGCCG
AAGATGCCCGCACGGCGTTTGAGACCGAGCTGAAAAAACGCACTGCCTTCTTCGCTTCGCTGGGTCACGATCTGCGCACA
CCGCTGCATGCGATCCTGGGCTATGCCGAGATCATGCAGGCCGAGCTGATGGGCCCGATGCCGGAAGTCTATGCAGACTA
TCCCTCGATCATCCACGAAAGCGGCACAGACCTCTTGCTCCTCGTCGATGACATCCTCGATCTGGCGCGCTCTGAAGCTG
GCCAGCCGCGGCTCGACCCGGAGCCGGTCGATCTTGCCGCCTCTGCCGAGTCGGTCATCCGCCAGCTGACGGGCCATGCA
GACCGCGCCGGGGTCACGCTGAAGCTGAAGGCGCAGGGGGAGGCATGGGCCGAGGCAGATGCCCGCGCCGTGCGCCAGAT
CTGGCAGAACCTCGTCTCCAACGCGATCAAGTATTCGGGCAGCGGCAAGACCGTAACGCTCGAAACCCGCATTGAAGGGG
GCGCGGCCATCCTCAGCGTGCAGGACCGGGGCGCGGGCATTCCTGCGGCCGATCTGGCGCGCATGACGCTGCCCTTCGAG
CAGGCAACCGGCGCAAAGCCCGGCACGGGCCTTGGCCTCTCGGTCGTGCGCCGCTTCGCCGAGCTGCATGGCGGCGAACT
GCGCCTCACCTCCAAGCCAGGACGGGGCACCAAAGCCGAAGTCATTCTGCCCCGCGCCAGTGAAGCGGATCTGTTGCCGC
TCGACGAAGCCGCCGAATAG

Upstream 100 bases:

>100_bases
TGACGGGGGAACCTCACCTTGTCTGTTTGCGACATTACAAATACAGCAGGTGCTCGTTCGGGCTGAAAATGCCTAATAAA
TCTCTCTGGGGTGTTAACGC

Downstream 100 bases:

>100_bases
GCCGCCGTCAGGCGCTTTCCAAAAACCTGTGGCCTCGTCTGGCGAAGCATGTAACCCTCGCGGGGTTATTATCAGCCAAG
GGGAATCTCAGATGAGAATG

Product: putative sensor histidine kinase DivJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MDPRMSQKRLQFVHVAWLAMCGGSGLAGLIAGAPLWPLLAIMVTAILPGLAGMALPAGDSPWRGLVVISWTLIALAGLIL
SGGGGSPLTVLLLAAPLAGLLAGARRMAAEAGVFAALALFMALVAGGLGWLPAPAPWAGALSVPFAFSGLVVSALMIWML
VHSGMAEKLQPVLERSERLPPENSSQTAPTAPIRAPLPQMPEAGVALLDVTLEGRLRAVAGDSFALPAFRPGAALAALFA
PDGLPENFGIADGRVTGEATLVSGQRVLITAETGSAGSAIVLFAPPETVADPAEDARTAFETELKKRTAFFASLGHDLRT
PLHAILGYAEIMQAELMGPMPEVYADYPSIIHESGTDLLLLVDDILDLARSEAGQPRLDPEPVDLAASAESVIRQLTGHA
DRAGVTLKLKAQGEAWAEADARAVRQIWQNLVSNAIKYSGSGKTVTLETRIEGGAAILSVQDRGAGIPAADLARMTLPFE
QATGAKPGTGLGLSVVRRFAELHGGELRLTSKPGRGTKAEVILPRASEADLLPLDEAAE

Sequences:

>Translated_539_residues
MDPRMSQKRLQFVHVAWLAMCGGSGLAGLIAGAPLWPLLAIMVTAILPGLAGMALPAGDSPWRGLVVISWTLIALAGLIL
SGGGGSPLTVLLLAAPLAGLLAGARRMAAEAGVFAALALFMALVAGGLGWLPAPAPWAGALSVPFAFSGLVVSALMIWML
VHSGMAEKLQPVLERSERLPPENSSQTAPTAPIRAPLPQMPEAGVALLDVTLEGRLRAVAGDSFALPAFRPGAALAALFA
PDGLPENFGIADGRVTGEATLVSGQRVLITAETGSAGSAIVLFAPPETVADPAEDARTAFETELKKRTAFFASLGHDLRT
PLHAILGYAEIMQAELMGPMPEVYADYPSIIHESGTDLLLLVDDILDLARSEAGQPRLDPEPVDLAASAESVIRQLTGHA
DRAGVTLKLKAQGEAWAEADARAVRQIWQNLVSNAIKYSGSGKTVTLETRIEGGAAILSVQDRGAGIPAADLARMTLPFE
QATGAKPGTGLGLSVVRRFAELHGGELRLTSKPGRGTKAEVILPRASEADLLPLDEAAE
>Mature_539_residues
MDPRMSQKRLQFVHVAWLAMCGGSGLAGLIAGAPLWPLLAIMVTAILPGLAGMALPAGDSPWRGLVVISWTLIALAGLIL
SGGGGSPLTVLLLAAPLAGLLAGARRMAAEAGVFAALALFMALVAGGLGWLPAPAPWAGALSVPFAFSGLVVSALMIWML
VHSGMAEKLQPVLERSERLPPENSSQTAPTAPIRAPLPQMPEAGVALLDVTLEGRLRAVAGDSFALPAFRPGAALAALFA
PDGLPENFGIADGRVTGEATLVSGQRVLITAETGSAGSAIVLFAPPETVADPAEDARTAFETELKKRTAFFASLGHDLRT
PLHAILGYAEIMQAELMGPMPEVYADYPSIIHESGTDLLLLVDDILDLARSEAGQPRLDPEPVDLAASAESVIRQLTGHA
DRAGVTLKLKAQGEAWAEADARAVRQIWQNLVSNAIKYSGSGKTVTLETRIEGGAAILSVQDRGAGIPAADLARMTLPFE
QATGAKPGTGLGLSVVRRFAELHGGELRLTSKPGRGTKAEVILPRASEADLLPLDEAAE

Specific function: Kinase required for the regulation of cell division and differentiation. Makes part of a signal transduction pathway, activating pleD by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=238, Percent_Identity=34.0336134453782, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1789149, Length=221, Percent_Identity=29.4117647058824, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI48994928, Length=234, Percent_Identity=32.4786324786325, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI145693157, Length=230, Percent_Identity=28.2608695652174, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1788713, Length=245, Percent_Identity=26.1224489795918, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1786912, Length=252, Percent_Identity=29.7619047619048, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI87082128, Length=225, Percent_Identity=28.4444444444444, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1786600, Length=224, Percent_Identity=29.0178571428571, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788549, Length=249, Percent_Identity=26.5060240963855, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1790861, Length=219, Percent_Identity=31.9634703196347, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788393, Length=231, Percent_Identity=26.8398268398268, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790551, Length=245, Percent_Identity=27.3469387755102, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=26.271186440678, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788279, Length=212, Percent_Identity=24.5283018867925, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786783, Length=230, Percent_Identity=24.7826086956522, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55900; Mature: 55900

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPRMSQKRLQFVHVAWLAMCGGSGLAGLIAGAPLWPLLAIMVTAILPGLAGMALPAGDS
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
PWRGLVVISWTLIALAGLILSGGGGSPLTVLLLAAPLAGLLAGARRMAAEAGVFAALALF
CCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MALVAGGLGWLPAPAPWAGALSVPFAFSGLVVSALMIWMLVHSGMAEKLQPVLERSERLP
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
PENSSQTAPTAPIRAPLPQMPEAGVALLDVTLEGRLRAVAGDSFALPAFRPGAALAALFA
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCEEEECCCCEECCCCCCCHHHHHHHC
PDGLPENFGIADGRVTGEATLVSGQRVLITAETGSAGSAIVLFAPPETVADPAEDARTAF
CCCCCCCCCCCCCEECCCEEEECCCEEEEEEECCCCCCEEEEECCCHHHCCCHHHHHHHH
ETELKKRTAFFASLGHDLRTPLHAILGYAEIMQAELMGPMPEVYADYPSIIHESGTDLLL
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHCCCCCEEE
LVDDILDLARSEAGQPRLDPEPVDLAASAESVIRQLTGHADRAGVTLKLKAQGEAWAEAD
EHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHH
ARAVRQIWQNLVSNAIKYSGSGKTVTLETRIEGGAAILSVQDRGAGIPAADLARMTLPFE
HHHHHHHHHHHHHHHHEECCCCCEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHCCCHH
QATGAKPGTGLGLSVVRRFAELHGGELRLTSKPGRGTKAEVILPRASEADLLPLDEAAE
HHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MDPRMSQKRLQFVHVAWLAMCGGSGLAGLIAGAPLWPLLAIMVTAILPGLAGMALPAGDS
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
PWRGLVVISWTLIALAGLILSGGGGSPLTVLLLAAPLAGLLAGARRMAAEAGVFAALALF
CCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MALVAGGLGWLPAPAPWAGALSVPFAFSGLVVSALMIWMLVHSGMAEKLQPVLERSERLP
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
PENSSQTAPTAPIRAPLPQMPEAGVALLDVTLEGRLRAVAGDSFALPAFRPGAALAALFA
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCEEEECCCCEECCCCCCCHHHHHHHC
PDGLPENFGIADGRVTGEATLVSGQRVLITAETGSAGSAIVLFAPPETVADPAEDARTAF
CCCCCCCCCCCCCEECCCEEEECCCEEEEEEECCCCCCEEEEECCCHHHCCCHHHHHHHH
ETELKKRTAFFASLGHDLRTPLHAILGYAEIMQAELMGPMPEVYADYPSIIHESGTDLLL
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHCCCCCEEE
LVDDILDLARSEAGQPRLDPEPVDLAASAESVIRQLTGHADRAGVTLKLKAQGEAWAEAD
EHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHH
ARAVRQIWQNLVSNAIKYSGSGKTVTLETRIEGGAAILSVQDRGAGIPAADLARMTLPFE
HHHHHHHHHHHHHHHHEECCCCCEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHCCCHH
QATGAKPGTGLGLSVVRRFAELHGGELRLTSKPGRGTKAEVILPRASEADLLPLDEAAE
HHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1438215; 11259647 [H]