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The map label for this gene is holA

Identifier: 114798351

GI number: 114798351

Start: 3694229

End: 3695260

Strand: Direct

Name: holA

Synonym: HNE_3559

Alternate gene names: NA

Gene position: 3694229-3695260 (Clockwise)

Preceding gene: 114798875

Following gene: NA

Centisome position: 99.71

GC content: 64.53

Gene sequence:

>1032_bases
ATGCTGCACAAGGGGCGCGCGGCCGAAGGCTTCGCCCGGCGGCCCGATCCGGAAGTCTGGGCCGTACTTGCGTTCAGCGA
AGATGAAGGCCTCGCCTTCGATGCCGGCCAGGCGCTGATCGCCGGCTGGGGCGGAAAACCGGGCATGGATGTCACCGTGC
TGGATGACGATGCCATCAAGAAAGAGCCCGCCCTTCTCTTCGATGCGCTCGAAGCTGTCTCGCTGCTGGGGGACTCCCGC
GCGGTTCGCGTGCGCACGAGCGGGGACAAGATCGCGGCTTTGCTGGCCGAAGCCATCGCCGCCGGTGACAAGGATCCCAG
GCGTTTTGCCGCCAAGCTGATCATCGAAGCGGGCAGCCTTCCGGGAAAGTCAAAGCTCCGGGCGGCAGCCGAAGGCGCAA
AGCGCGCCGCCTGTCTTCAGTTCTTCGCCGAGGAAGACACCGATGTTGCGAGCCGGGTGAAGACGGCCCTGCTCGCAGAG
GGCGCGGTTATAGACCCCCCTGCCCTGGACGCTTTCGTGGGCGACCTGCCGGGACATCGCGCACTCGCCAATTCCGAGAT
CGAGAAACTTGCGCTTTATGCCAGAGGCCTGGGACGCCCGCTAAACCTGGAAGACGTTCGGGCGCTGTCAGCGACGGATG
TGAAACAGGCCATCTCCGGCGCCGTGAATGCGGCCCTTGATGGTCACCCCGGCGCGGCGCAGACCGCGCTCGACAAGCTT
TCCGAGAACGGAACGAGCGGCATATCAATTCTGCGGTCCCTCCAGATGGAGGTTCTCCGAATGCTCAGCGCGCATGAAAA
GATTGCCGGCGGAGACGGAAATCCGGGAAAGTACCTTCGCCCGCCGGTCTGGCCCAGCGACTGGCCCGCCTTCCGCGTGC
GCCTTGGCAAGTGGCCCGCGCGGCGCCTGATGCGCGTGATGGAACGAATTCATGATGCCGAGCGCCAGACCAAACTGGCC
GGACCAATCGGGGACCCTGTGGTCCGCCTGCTGATCAACGATCTGGCAAAGGCCGCTGAAAACGTTCGTTAA

Upstream 100 bases:

>100_bases
ATGGCGATATTGCCGCGCAGACGGATGCGGGCGACCGGGCAATGCGGGTTCTGGCCAAGCAGATTGCCGACGACATTCGC
CTGAAGTTCGCAGGCTCCTG

Downstream 100 bases:

>100_bases
CGGATTATTATTCCGCAGTCCGGCGCTTAGCGGTCAAGCGGCGGCAGACTTCATCGAGCTGTTCCAGATCACGATACTTG
ATCCGGATCTCCCCGCCATT

Product: DNA polymerase III subunit delta

Products: diphosphate; DNAn+1

Alternate protein names: DNA Polymerase III Delta Subunit; DNA Polymerase III Delta

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MLHKGRAAEGFARRPDPEVWAVLAFSEDEGLAFDAGQALIAGWGGKPGMDVTVLDDDAIKKEPALLFDALEAVSLLGDSR
AVRVRTSGDKIAALLAEAIAAGDKDPRRFAAKLIIEAGSLPGKSKLRAAAEGAKRAACLQFFAEEDTDVASRVKTALLAE
GAVIDPPALDAFVGDLPGHRALANSEIEKLALYARGLGRPLNLEDVRALSATDVKQAISGAVNAALDGHPGAAQTALDKL
SENGTSGISILRSLQMEVLRMLSAHEKIAGGDGNPGKYLRPPVWPSDWPAFRVRLGKWPARRLMRVMERIHDAERQTKLA
GPIGDPVVRLLINDLAKAAENVR

Sequences:

>Translated_343_residues
MLHKGRAAEGFARRPDPEVWAVLAFSEDEGLAFDAGQALIAGWGGKPGMDVTVLDDDAIKKEPALLFDALEAVSLLGDSR
AVRVRTSGDKIAALLAEAIAAGDKDPRRFAAKLIIEAGSLPGKSKLRAAAEGAKRAACLQFFAEEDTDVASRVKTALLAE
GAVIDPPALDAFVGDLPGHRALANSEIEKLALYARGLGRPLNLEDVRALSATDVKQAISGAVNAALDGHPGAAQTALDKL
SENGTSGISILRSLQMEVLRMLSAHEKIAGGDGNPGKYLRPPVWPSDWPAFRVRLGKWPARRLMRVMERIHDAERQTKLA
GPIGDPVVRLLINDLAKAAENVR
>Mature_343_residues
MLHKGRAAEGFARRPDPEVWAVLAFSEDEGLAFDAGQALIAGWGGKPGMDVTVLDDDAIKKEPALLFDALEAVSLLGDSR
AVRVRTSGDKIAALLAEAIAAGDKDPRRFAAKLIIEAGSLPGKSKLRAAAEGAKRAACLQFFAEEDTDVASRVKTALLAE
GAVIDPPALDAFVGDLPGHRALANSEIEKLALYARGLGRPLNLEDVRALSATDVKQAISGAVNAALDGHPGAAQTALDKL
SENGTSGISILRSLQMEVLRMLSAHEKIAGGDGNPGKYLRPPVWPSDWPAFRVRLGKWPARRLMRVMERIHDAERQTKLA
GPIGDPVVRLLINDLAKAAENVR

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.7

Molecular weight: Translated: 36457; Mature: 36457

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHKGRAAEGFARRPDPEVWAVLAFSEDEGLAFDAGQALIAGWGGKPGMDVTVLDDDAIK
CCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEECCCEEEEECCCCCCCEEEEECCHHHH
KEPALLFDALEAVSLLGDSRAVRVRTSGDKIAALLAEAIAAGDKDPRRFAAKLIIEAGSL
CCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
PGKSKLRAAAEGAKRAACLQFFAEEDTDVASRVKTALLAEGAVIDPPALDAFVGDLPGHR
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCH
ALANSEIEKLALYARGLGRPLNLEDVRALSATDVKQAISGAVNAALDGHPGAAQTALDKL
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SENGTSGISILRSLQMEVLRMLSAHEKIAGGDGNPGKYLRPPVWPSDWPAFRVRLGKWPA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHH
RRLMRVMERIHDAERQTKLAGPIGDPVVRLLINDLAKAAENVR
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLHKGRAAEGFARRPDPEVWAVLAFSEDEGLAFDAGQALIAGWGGKPGMDVTVLDDDAIK
CCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEECCCEEEEECCCCCCCEEEEECCHHHH
KEPALLFDALEAVSLLGDSRAVRVRTSGDKIAALLAEAIAAGDKDPRRFAAKLIIEAGSL
CCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
PGKSKLRAAAEGAKRAACLQFFAEEDTDVASRVKTALLAEGAVIDPPALDAFVGDLPGHR
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCH
ALANSEIEKLALYARGLGRPLNLEDVRALSATDVKQAISGAVNAALDGHPGAAQTALDKL
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SENGTSGISILRSLQMEVLRMLSAHEKIAGGDGNPGKYLRPPVWPSDWPAFRVRLGKWPA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHH
RRLMRVMERIHDAERQTKLAGPIGDPVVRLLINDLAKAAENVR
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA